CO5160319A1 - Formulaciones de liberacion controlada de metamizol - Google Patents
Formulaciones de liberacion controlada de metamizolInfo
- Publication number
- CO5160319A1 CO5160319A1 CO99068639A CO99068639A CO5160319A1 CO 5160319 A1 CO5160319 A1 CO 5160319A1 CO 99068639 A CO99068639 A CO 99068639A CO 99068639 A CO99068639 A CO 99068639A CO 5160319 A1 CO5160319 A1 CO 5160319A1
- Authority
- CO
- Colombia
- Prior art keywords
- controlled release
- release formulations
- metamizol
- subjecting
- fatty acid
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940120889 dipyrone Drugs 0.000 title abstract 2
- LVWZTYCIRDMTEY-UHFFFAOYSA-N metamizole Chemical compound O=C1C(N(CS(O)(=O)=O)C)=C(C)N(C)N1C1=CC=CC=C1 LVWZTYCIRDMTEY-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- -1 fatty acid compound Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 238000007909 melt granulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
FORMULACIONES DE LIBERACIÓN CONTROLADA DE METAMIZOLSe obtienen formulaciones de liberación controlada sólidas, de administración por vía oral al someter el ingrediente activo y un compuesto de ácido graso a proceso de granulación por fusión y mezclado posterior del granulado obtenido con un polímero hidrofílico y excipientes convencionales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI002365A IT1303693B1 (it) | 1998-11-03 | 1998-11-03 | Composizioni a rilascio controllato di metamizolo. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5160319A1 true CO5160319A1 (es) | 2002-05-30 |
Family
ID=11380995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99068639A CO5160319A1 (es) | 1998-11-03 | 1999-10-29 | Formulaciones de liberacion controlada de metamizol |
Country Status (6)
| Country | Link |
|---|---|
| AR (1) | AR020998A1 (es) |
| AU (1) | AU1155000A (es) |
| CO (1) | CO5160319A1 (es) |
| IT (1) | IT1303693B1 (es) |
| PE (1) | PE20001231A1 (es) |
| WO (1) | WO2000025750A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19920415A1 (de) * | 1999-05-04 | 2000-11-09 | Hexal Ag | Metamizol enthaltende, kontrolliert freisetzende pharmazeutische Zusammensetzung |
| DE102008022520A1 (de) * | 2008-05-07 | 2009-11-12 | Bayer Animal Health Gmbh | Feste Arzneimittelformulierung mit verzögerter Freisetzung |
| EP3265097A4 (en) * | 2015-03-03 | 2018-11-07 | Kindred Biosciences Inc. | Compositions and methods for treatment and prevention of pyrexia in horses |
| WO2018087109A1 (de) | 2016-11-08 | 2018-05-17 | Grünenthal GmbH | Multipartikuläre arzneiform mit kontrollierter freisetzung von metamizol |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0971743B1 (de) * | 1997-04-18 | 2006-07-12 | Fritz Stanislaus | Stabilisiertes arzneimittel enthaltend cysteinylderivate |
-
1998
- 1998-11-03 IT IT1998MI002365A patent/IT1303693B1/it active
-
1999
- 1999-10-27 WO PCT/EP1999/008120 patent/WO2000025750A1/en not_active Ceased
- 1999-10-27 AU AU11550/00A patent/AU1155000A/en not_active Abandoned
- 1999-10-28 AR ARP990105435A patent/AR020998A1/es unknown
- 1999-10-29 CO CO99068639A patent/CO5160319A1/es unknown
- 1999-11-03 PE PE1999001101A patent/PE20001231A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20001231A1 (es) | 2000-11-29 |
| AU1155000A (en) | 2000-05-22 |
| WO2000025750A1 (en) | 2000-05-11 |
| AR020998A1 (es) | 2002-06-05 |
| ITMI982365A1 (it) | 2000-05-03 |
| IT1303693B1 (it) | 2001-02-23 |
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