|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
IL47062A
(en)
|
1975-04-10 |
1979-07-25 |
Yeda Res & Dev |
Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
|
|
US4665077A
(en)
|
1979-03-19 |
1987-05-12 |
The Upjohn Company |
Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4737456A
(en)
|
1985-05-09 |
1988-04-12 |
Syntex (U.S.A.) Inc. |
Reducing interference in ligand-receptor binding assays
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5811310A
(en)
|
1986-09-30 |
1998-09-22 |
Albert Einstein College Of Medicine Of Yeshiva Univ. |
The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease
|
|
US6893625B1
(en)
|
1986-10-27 |
2005-05-17 |
Royalty Pharma Finance Trust |
Chimeric antibody with specificity to human B cell surface antigen
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US5231000A
(en)
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
US4892538A
(en)
|
1987-11-17 |
1990-01-09 |
Brown University Research Foundation |
In vivo delivery of neurotransmitters by implanted, encapsulated cells
|
|
US5283187A
(en)
|
1987-11-17 |
1994-02-01 |
Brown University Research Foundation |
Cell culture-containing tubular capsule produced by co-extrusion
|
|
US5506126A
(en)
|
1988-02-25 |
1996-04-09 |
The General Hospital Corporation |
Rapid immunoselection cloning method
|
|
HUT53672A
(en)
|
1988-02-25 |
1990-11-28 |
Gen Hospital Corp |
Quick immunoselective cloning process
|
|
IL85746A
(en)
|
1988-03-15 |
1994-05-30 |
Yeda Res & Dev |
Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases
|
|
US4861579A
(en)
|
1988-03-17 |
1989-08-29 |
American Cyanamid Company |
Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
|
|
FI891226A7
(fi)
|
1988-04-28 |
1989-10-29 |
The Board Of Trustees Of The Leland |
Anti-T-solun reseptorideterminantit autoimmuunisairauden hoitoon
|
|
WO1990008187A1
(en)
|
1989-01-19 |
1990-07-26 |
Dana Farber Cancer Institute |
Soluble two domain cd2 protein
|
|
CA2046909A1
(en)
|
1989-03-21 |
1990-09-22 |
Mark D. Howell |
Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
|
|
AU652540B2
(en)
|
1989-07-19 |
1994-09-01 |
Xoma Corporation |
T cell receptor peptides as therapeutics for autoimmune and malignant disease
|
|
US5154924A
(en)
|
1989-09-07 |
1992-10-13 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
NZ236819A
(en)
|
1990-02-03 |
1993-07-27 |
Max Planck Gesellschaft |
Enzymatic cleavage of fusion proteins; fusion proteins; recombinant dna and pharmaceutical compositions
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
JP2780507B2
(ja)
|
1991-03-29 |
1998-07-30 |
松下電器産業株式会社 |
内燃機関用フィルタ再生装置
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
WO1993006217A1
(en)
|
1991-09-19 |
1993-04-01 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES
|
|
JPH07509444A
(ja)
|
1991-11-26 |
1995-10-19 |
アルカーメス・インコーポレーテツド |
トランスフェリンセレプター特異的抗体−神経薬又は診断薬複合体の製造法
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
AU4528493A
(en)
|
1992-06-04 |
1994-01-04 |
Regents Of The University Of California, The |
In vivo gene therapy with intron-free sequence of interest
|
|
ATE191853T1
(de)
|
1992-07-27 |
2000-05-15 |
Us Health |
Zielgerichte liposome zur blut-hirne schranke
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
ES2091684T3
(es)
|
1992-11-13 |
1996-11-01 |
Idec Pharma Corp |
Aplicacion terapeutica de anticuerpos quimericos y radiomarcados contra el antigeno de diferenciacion restringida de los linfocitos b humanos para el tratamiento del linfoma de las celulas b.
|
|
US7744877B2
(en)
|
1992-11-13 |
2010-06-29 |
Biogen Idec Inc. |
Expression and use of anti-CD20 Antibodies
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
WO1994017197A1
(fr)
|
1993-01-25 |
1994-08-04 |
Takeda Chemical Industries, Ltd. |
ANTICORPS DIRIGE CONTRE LE β-AMYLOIDE OU UN DERIVE DE CE DERNIER ET SON UTILISATION
|
|
US5955317A
(en)
|
1993-01-25 |
1999-09-21 |
Takeda Chemical Industries, Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
US5417972A
(en)
|
1993-08-02 |
1995-05-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM
|
|
US5595721A
(en)
|
1993-09-16 |
1997-01-21 |
Coulter Pharmaceutical, Inc. |
Radioimmunotherapy of lymphoma using anti-CD20
|
|
US5443953A
(en)
|
1993-12-08 |
1995-08-22 |
Immunomedics, Inc. |
Preparation and use of immunoconjugates
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5910486A
(en)
|
1994-09-06 |
1999-06-08 |
Uab Research Foundation |
Methods for modulating protein function in cells using, intracellular antibody homologues
|
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
US5688651A
(en)
|
1994-12-16 |
1997-11-18 |
Ramot University Authority For Applied Research And Development Ltd. |
Prevention of protein aggregation
|
|
US5586553A
(en)
|
1995-02-16 |
1996-12-24 |
Minimed Inc. |
Transcutaneous sensor insertion set
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US6015555A
(en)
|
1995-05-19 |
2000-01-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
|
AU5976996A
(en)
|
1995-06-06 |
1996-12-24 |
Stemcell Therapeutics L.L.C. |
Glycoprotein gp105 on bl3 hematopoietic stem cells
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
MX9800684A
(es)
|
1995-07-27 |
1998-04-30 |
Genentech Inc |
Formulacion de proteinas liofilizadas isotonicas estables.
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
DE19528388A1
(de)
|
1995-08-02 |
1997-02-06 |
Hans Peter Prof Dr Med Zenner |
Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs
|
|
CA2229043C
(en)
|
1995-08-18 |
2016-06-07 |
Morphosys Gesellschaft Fur Proteinoptimierung Mbh |
Protein/(poly)peptide libraries
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
US20010056066A1
(en)
|
1996-07-26 |
2001-12-27 |
Smithkline Beecham Corporation |
Method of treating immune cell mediated systemic diseases
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
DK0999853T3
(da)
|
1997-06-13 |
2003-04-22 |
Genentech Inc |
Stabiliseret antostofformulering
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
EP0994903B1
(en)
|
1997-06-24 |
2005-05-25 |
Genentech, Inc. |
Methods and compositions for galactosylated glycoproteins
|
|
WO1999002567A2
(en)
|
1997-07-08 |
1999-01-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods for producing homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
|
AU759779B2
(en)
|
1997-10-31 |
2003-05-01 |
Genentech Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
JP4460155B2
(ja)
|
1997-12-05 |
2010-05-12 |
ザ・スクリプス・リサーチ・インステイチユート |
マウス抗体のヒト化
|
|
DE69937291T2
(de)
|
1998-04-02 |
2008-07-10 |
Genentech, Inc., South San Francisco |
Antikörpervarianten und fragmente davon
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US6242195B1
(en)
|
1998-04-02 |
2001-06-05 |
Genentech, Inc. |
Methods for determining binding of an analyte to a receptor
|
|
JP4334141B2
(ja)
|
1998-04-20 |
2009-09-30 |
グリカート バイオテクノロジー アクチェンゲゼルシャフト |
抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
|
|
JP2002522511A
(ja)
|
1998-08-11 |
2002-07-23 |
アイデック ファーマスーティカルズ コーポレイション |
抗ｃｄ２０抗体の投与を含むｂ細胞リンパ腫の併用療法
|
|
US6224866B1
(en)
|
1998-10-07 |
2001-05-01 |
Biocrystal Ltd. |
Immunotherapy of B cell involvement in progression of solid, nonlymphoid tumors
|
|
ES2265693T3
(es)
|
1998-10-16 |
2007-02-16 |
Biogen Idec Ma Inc. |
Proteinas de fusion con interferon-beta y usos.
|
|
TR200101302T2
(tr)
|
1998-11-09 |
2001-10-22 |
Idec Pharmaceuticals Corporation |
BMT yada PBSC transplantı alan hastalarda in vitro ya da in vivo temizleyici madde olarak kimerik anti-CD20 antikorunun kullanımı.
|
|
ES2543819T3
(es)
|
1998-11-09 |
2015-08-24 |
Biogen Inc. |
Tratamiento de neoplasias hematológicas asociadas con células tumorales circulantes utilizando anticuerpo quimérico dirigido contra CD20
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
BR0008758A
(pt)
|
1999-01-15 |
2001-12-04 |
Genentech Inc |
Variantes de polipeptìdeos parentais com funçãoefetora alterada, polipeptìdeos, composição ácidonucleico isolado, vetor, célula hospedeira,método para produzir uma variante depolipeptìdeo, método para o tratamento de umadesordem em mamìferos e método para produziruma região fc variante
|
|
US6897044B1
(en)
|
1999-01-28 |
2005-05-24 |
Biogen Idec, Inc. |
Production of tetravalent antibodies
|
|
EP1035172A3
(en)
|
1999-03-12 |
2002-11-27 |
Fuji Photo Film Co., Ltd. |
Azomethine compound and oily magenta ink
|
|
CA2369292C
(en)
|
1999-04-09 |
2010-09-21 |
Kyowa Hakko Kogyo Co. Ltd. |
Method of modulating the activity of functional immune molecules
|
|
IL129427A0
(en)
|
1999-04-13 |
2000-02-17 |
Yeda Res & Dev |
Preparation of biologically active molecules
|
|
SE9901428D0
(sv)
|
1999-04-21 |
1999-04-21 |
Karolinska Innovations Ab |
Amphibodies
|
|
KR20020027311A
(ko)
|
1999-05-07 |
2002-04-13 |
제넨테크, 인크. |
Ｂ 세포 표면 마커에 결합하는 길항물질을 이용한자가면역 질환의 치료
|
|
WO2000074718A1
(en)
|
1999-06-09 |
2000-12-14 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
ITMI991299A1
(it)
|
1999-06-11 |
2000-12-11 |
Consiglio Nazionale Ricerche |
Uso di anticorpi contro antigeni di superficie per il trattamento della malattia trapianto contro ospite
|
|
DK1409654T3
(da)
|
1999-06-16 |
2008-12-08 |
Boston Biomedical Res Inst |
Immunologisk styring af beta-amyloid-niveauer in vivo
|
|
DE19930748C2
(de)
|
1999-07-02 |
2001-05-17 |
Infineon Technologies Ag |
Verfahren zur Herstellung von EEPROM- und DRAM-Grabenspeicherzellbereichen auf einem Chip
|
|
HK1047702A1
(zh)
|
1999-07-12 |
2003-03-07 |
Genentech Inc. |
用与cd20结合的拮抗剂阻断对外来抗原的免疫应答
|
|
US8557244B1
(en)
|
1999-08-11 |
2013-10-15 |
Biogen Idec Inc. |
Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
|
|
WO2001010462A1
(en)
|
1999-08-11 |
2001-02-15 |
Idec Pharmaceuticals Corporation |
Treatment of patients having non-hodgkins lymphoma with bone marrow involvement with anti-cd20 antibodies
|
|
US6451284B1
(en)
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
AU6929100A
(en)
|
1999-08-23 |
2001-03-19 |
Biocrystal Limited |
Methods and compositions for immunotherapy of b cell involvement in promotion ofa disease condition comprising multiple sclerosis
|
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
|
JP2003512821A
(ja)
|
1999-10-04 |
2003-04-08 |
メディカゴ インコーポレイテッド |
外来性遺伝子の転写調節方法
|
|
WO2001029246A1
(fr)
|
1999-10-19 |
2001-04-26 |
Kyowa Hakko Kogyo Co., Ltd. |
Procede de production d'un polypeptide
|
|
US20020006404A1
(en)
|
1999-11-08 |
2002-01-17 |
Idec Pharmaceuticals Corporation |
Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
WO2002004021A1
(en)
|
2000-07-12 |
2002-01-17 |
Idec Pharmaceuticals Corporation |
Treatment of b cell malignancies using combination of b cell depleting antibody and immune modulating antibody related applications
|
|
IL149500A0
(en)
|
1999-11-08 |
2002-11-10 |
Idec Pharma Corp |
Treatment of b cell malignancies using anti-cd40l antibodies in combination with anti-cd20 antibodies and/or chemotherapeutics and radiotherapy
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
AU784312B2
(en)
|
1999-11-29 |
2006-03-09 |
Bellus Health (International) Limited |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
CA2395660A1
(en)
|
1999-12-29 |
2001-07-12 |
Immunogen, Inc. |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
|
US20020127652A1
(en)
|
2000-02-11 |
2002-09-12 |
Schambye Hans Thalsgard |
Follicle stimulating hormones
|
|
EP1125905A1
(en)
|
2000-02-16 |
2001-08-22 |
Pepscan Systems B.V. |
Segment synthesis
|
|
IL151906A0
(en)
|
2000-03-24 |
2003-04-10 |
Chiron Corp |
Methods of therapy for non-hodgkin's lymphoma using a combination of an antibody to cd20 and interleukin-2
|
|
US20030185796A1
(en)
|
2000-03-24 |
2003-10-02 |
Chiron Corporation |
Methods of therapy for non-hodgkin's lymphoma
|
|
EP1283722A1
(en)
|
2000-03-31 |
2003-02-19 |
Idec Pharmaceuticals Corporation |
Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma
|
|
DK1272647T3
(en)
|
2000-04-11 |
2014-12-15 |
Genentech Inc |
Multivalent antibodies and uses thereof
|
|
MXPA02010507A
(es)
|
2000-04-25 |
2003-05-14 |
Idec Pharma Corp |
Administracion intratecal de rituximab para el tratamiento de linfomas del sistema nervioso central.
|
|
CA2411102A1
(en)
|
2000-06-20 |
2001-12-27 |
Idec Pharmaceutical Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
US7534772B2
(en)
|
2000-06-22 |
2009-05-19 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
WO2002002597A2
(en)
|
2000-06-30 |
2002-01-10 |
Maxygen Aps |
Peptide extended glycosylated polypeptides
|
|
US20030148404A1
(en)
|
2000-07-27 |
2003-08-07 |
Ramot University Authority For Applied Research & Industrial Development Ltd. |
Peptides and substances, methods and devices using same for diagnosing and treating neurodegenerative disorders
|
|
CA2313828A1
(en)
|
2000-08-01 |
2002-02-01 |
Institut De Recherches Cliniques De Montreal/Ircm |
Post-translational processing of .beta.-secretase (bace): the pro-and transmembrane/cytosolic domains affect its cellular activity and amyloid a.beta. production
|
|
CN1592645A
(zh)
|
2000-09-18 |
2005-03-09 |
拜奥根Idec公司 |
使用b细胞耗尽/免疫调节抗体组合治疗自身免疫病的联合疗法
|
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
EA013563B1
(ru)
|
2000-10-06 |
2010-06-30 |
Киова Хакко Кирин Ко., Лтд. |
Трансгенное животное, продуцирующее антитела с измененными углеводными цепями, способ получения антител и содержащее антитела лекарственное средство
|
|
AU2002213357A1
(en)
|
2000-10-20 |
2002-05-06 |
Idec Pharmaceuticals Corporation |
Variant igg3 rituxan r and therapeutic use thereof
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
DK1354034T3
(da)
|
2000-11-30 |
2008-03-25 |
Medarex Inc |
Transgene transchromosomale gnavere til fremstilling af humane antistoffer
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
CA2436789A1
(en)
|
2000-12-19 |
2002-08-22 |
Palatin Technologies, Inc. |
Identification of target-specific folding sites in peptides and proteins
|
|
KR20030074693A
(ko)
|
2000-12-28 |
2003-09-19 |
알투스 바이올로직스 인코포레이티드 |
전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
NZ545176A
(en)
|
2001-01-29 |
2008-05-30 |
Biogen Idec Inc |
Modified antibodies reactive with CD20 and methods of use
|
|
US20030103971A1
(en)
|
2001-11-09 |
2003-06-05 |
Kandasamy Hariharan |
Immunoregulatory antibodies and uses thereof
|
|
WO2002078766A2
(en)
|
2001-04-02 |
2002-10-10 |
Genentech, Inc. |
Combination therapy
|
|
JP2005500018A
(ja)
|
2001-04-02 |
2005-01-06 |
アイデック ファーマスーティカルズ コーポレイション |
ＧｎＴＩＩＩと同時発現する組換え抗体
|
|
ES2312569T3
(es)
|
2001-04-30 |
2009-03-01 |
Eli Lilly And Company |
Anticuerpos humanizados.
|
|
ATE420114T1
(de)
|
2001-04-30 |
2009-01-15 |
Lilly Co Eli |
Humanisierte antikörper die das beta-amyloid peptid erkennen& x9;
|
|
DE10121982B4
(de)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
|
|
WO2003061694A1
(en)
|
2001-05-10 |
2003-07-31 |
Seattle Genetics, Inc. |
Immunosuppression of the humoral immune response by anti-cd20 antibodies
|
|
AU2002315168A1
(en)
|
2001-06-14 |
2003-01-02 |
Intermune, Inc. |
Combination therapy of gamma-interferon and b cell specific antibodies
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
ATE454137T1
(de)
|
2001-07-25 |
2010-01-15 |
Facet Biotech Corp |
Stabile lyophilisierte pharmazeutische formulierung des igg-antikörpers daclizumab
|
|
CA2455365C
(en)
|
2001-08-03 |
2014-07-29 |
Glycart Biotechnology Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
ES2391905T3
(es)
|
2001-08-17 |
2012-11-30 |
Washington University |
Método de ensayo para la enfermedad de alzheimer
|
|
US20040192898A1
(en)
|
2001-08-17 |
2004-09-30 |
Jia Audrey Yunhua |
Anti-abeta antibodies
|
|
JP4424987B2
(ja)
|
2001-09-20 |
2010-03-03 |
ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム |
Ｅｌｉｓａアッセイを用いた循環する治療抗体、抗原および抗原／抗体複合体の測定
|
|
ATE430580T1
(de)
|
2001-10-25 |
2009-05-15 |
Genentech Inc |
Glycoprotein-zusammensetzungen
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
JP2005538034A
(ja)
|
2001-12-07 |
2005-12-15 |
カイロン コーポレイション |
非ホジキンリンパ腫の治療方法
|
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
|
CN100522999C
(zh)
|
2002-02-14 |
2009-08-05 |
免疫医疗公司 |
抗cd20抗体及其融合蛋白和使用方法
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20030180292A1
(en)
|
2002-03-14 |
2003-09-25 |
Idec Pharmaceuticals |
Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy
|
|
WO2003085119A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
METHOD OF ENHANCING ACTIVITY OF ANTIBODY COMPOSITION OF BINDING TO FcϜ RECEPTOR IIIa
|
|
CN1930288B
(zh)
|
2002-04-09 |
2012-08-08 |
协和发酵麒麟株式会社 |
基因组被修饰的细胞
|
|
ES2362419T3
(es)
|
2002-04-09 |
2011-07-05 |
Kyowa Hakko Kirin Co., Ltd. |
Células con depresión o deleción de la actividad de la proteína que participa en el transporte de gdp-fucosa.
|
|
CA2481920A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Antibody composition-containing medicament
|
|
WO2003084570A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
DRUG CONTAINING ANTIBODY COMPOSITION APPROPRIATE FOR PATIENT SUFFERING FROM FcϜRIIIa POLYMORPHISM
|
|
JPWO2003085118A1
(ja)
|
2002-04-09 |
2005-08-11 |
協和醗酵工業株式会社 |
抗体組成物の製造方法
|
|
US20030219818A1
(en)
|
2002-05-10 |
2003-11-27 |
Bohen Sean P. |
Methods and compositions for determining neoplastic disease responsiveness to antibody therapy
|
|
CA2494104A1
(en)
|
2002-07-31 |
2004-04-22 |
Seattle Genetics, Inc. |
Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
AR040778A1
(es)
|
2002-08-06 |
2005-04-20 |
Glaxo Group Ltd |
Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
|
|
WO2004020454A2
(en)
|
2002-08-30 |
2004-03-11 |
Biorexis Pharmaceutical Corporation |
Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains
|
|
MXPA05003621A
(es)
|
2002-10-09 |
2005-10-19 |
Rinat Neuroscience Corp |
Metodos de tratamiento de la enfermedad de alzheimer usando anticuerpos dirigidos contra el peptido beta amiloide y composiciones de los mismos.
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
WO2004035607A2
(en)
|
2002-10-17 |
2004-04-29 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
KR101186210B1
(ko)
|
2002-12-03 |
2012-10-08 |
블랜체트 록펠러 뉴로사이언시즈 인스티튜트 |
혈뇌장벽을 통과하는 물질 수송용 인공 저밀도 지단백질 운반체
|
|
PT1572744E
(pt)
|
2002-12-16 |
2010-09-07 |
Genentech Inc |
Variantes de imunoglobulina e utilizações destas
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
DK1610820T4
(da)
|
2003-04-04 |
2013-11-04 |
Genentech Inc |
Høj-koncentration antistof- og proteinformuleringer
|
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
|
AU2004279742A1
(en)
|
2003-10-08 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Fused protein composition
|
|
EP1705251A4
(en)
|
2003-10-09 |
2009-10-28 |
Kyowa Hakko Kirin Co Ltd |
PROCESS FOR PRODUCING ANTIBODY COMPOSITION BY RNA INHIBITION OF FUNCTION OF $ G (A) 1,6-FUCOSYLTRANSFERASE
|
|
ME01775B
(me)
|
2003-11-05 |
2011-02-28 |
Glycart Biotechnology Ag |
Cd20 antitijela sa povećanim afinitetom vezivanja za fc receptor i efektornom funkcijom
|
|
NZ583292A
(en)
|
2003-11-06 |
2012-03-30 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugation to ligands
|
|
EP1701979A2
(en)
|
2003-12-03 |
2006-09-20 |
Xencor, Inc. |
Optimized antibodies that target the epidermal growth factor receptor
|
|
JPWO2005053742A1
(ja)
|
2003-12-04 |
2007-06-28 |
協和醗酵工業株式会社 |
抗体組成物を含有する医薬
|
|
AU2004297616B2
(en)
|
2003-12-04 |
2008-12-18 |
Xencor, Inc. |
Methods of generating variant proteins with increased host string content and compositions thereof
|
|
EP2053062A1
(en)
*
|
2004-03-24 |
2009-04-29 |
Xencor, Inc. |
Immunoglobin variants outside the Fc region
|
|
CA2561686C
(en)
|
2004-03-31 |
2014-12-02 |
Genentech, Inc. |
Humanized anti-tgf-beta antibodies
|
|
BR122019012028B1
(pt)
|
2004-04-13 |
2023-09-26 |
F. Hoffmann-La Roche Ag |
Anticorpos anti-p-selectina, molécula de ácido nucléico, vetor, e composição
|
|
GB0412186D0
(en)
|
2004-05-28 |
2004-06-30 |
Univ Cambridge Tech |
Production of recombinant protein
|
|
TWI380996B
(zh)
|
2004-09-17 |
2013-01-01 |
Hoffmann La Roche |
抗ｏｘ４０ｌ抗體
|
|
CN101061140B
(zh)
|
2004-09-17 |
2015-07-01 |
多曼蒂斯有限公司 |
单价结合cd40l的组合物和应用方法
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
US7697967B2
(en)
|
2005-12-28 |
2010-04-13 |
Abbott Diabetes Care Inc. |
Method and apparatus for providing analyte sensor insertion
|
|
CA2595380A1
(en)
|
2005-01-28 |
2006-08-03 |
Wyeth |
Stabilized liquid polypeptide formulations
|
|
GT200600031A
(es)
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
|
ES2424042T3
(es)
|
2005-06-07 |
2013-09-26 |
Esbatech - A Novartis Company Llc |
Anticuerpos estables y solubles que inhiben TNF±
|
|
US8142781B2
(en)
|
2005-10-07 |
2012-03-27 |
Armagen Technologies, Inc. |
Fusion proteins for blood-brain barrier delivery
|
|
BRPI0619605B8
(pt)
|
2005-12-12 |
2021-05-25 |
Hoffmann La Roche |
composições compreendendo moléculas de anticorpos contra amilóide beta4 com glicosilação na região variável, usos das mesmas, método de preparação de uma molécula de anticorpo, e kit
|
|
DE102006013531A1
(de)
|
2006-03-24 |
2007-09-27 |
Lts Lohmann Therapie-Systeme Ag |
Polylactid-Nanopartikel
|
|
RU2008142359A
(ru)
|
2006-03-28 |
2010-05-10 |
Ф.Хоффманн-Ля Рош Аг (Ch) |
Композиция человеческого моноклонального антитела к igf-1r
|
|
EP2029621A2
(en)
|
2006-06-07 |
2009-03-04 |
Wisconsin Alumni Research Foundation |
Blood-brain barrier targeting antibodies
|
|
US20080070251A1
(en)
|
2006-06-30 |
2008-03-20 |
Kaufman Randal J |
Method of Producing Factor VIII Proteins by Recombinant Methods
|
|
WO2008022349A2
(en)
|
2006-08-18 |
2008-02-21 |
Armagen Technologies, Inc. |
Agents for blood-brain barrier delivery
|
|
KR101106795B1
(ko)
|
2006-08-31 |
2012-01-18 |
에프. 호프만-라 로슈 아게 |
인슐린-유사 성장 인자-ｉ의 제조 방법
|
|
US9382327B2
(en)
*
|
2006-10-10 |
2016-07-05 |
Vaccinex, Inc. |
Anti-CD20 antibodies and methods of use
|
|
CN101553504A
(zh)
|
2006-12-11 |
2009-10-07 |
豪夫迈·罗氏有限公司 |
Aβ抗体胃肠外制剂
|
|
US20080226635A1
(en)
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
|
CN101245107B
(zh)
|
2007-02-14 |
2010-10-13 |
中国人民解放军军事医学科学院生物工程研究所 |
抗人转铁蛋白受体人源抗体及其应用
|
|
US9745367B2
(en)
|
2007-03-23 |
2017-08-29 |
Novelmed Theraputics, Inc. |
Alternative pathway specific antibodies for treating arthritis
|
|
WO2008135380A1
(en)
|
2007-05-02 |
2008-11-13 |
F. Hoffmann-La Roche Ag |
Method for stabilizing a protein
|
|
US8062864B2
(en)
|
2007-05-21 |
2011-11-22 |
Alderbio Holdings Llc |
Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
|
|
WO2009018411A1
(en)
|
2007-07-31 |
2009-02-05 |
Regeneron Pharmaceuticals, Inc. |
Human antibodies to human cd20 and method of using thereof
|
|
UA100699C2
(ru)
|
2007-07-31 |
2013-01-25 |
Ридженерон Фармасьютикалз, Инк. |
Антитело к cd20 человека и его применение для лечения заболевания или состояния опосредованного cd20
|
|
ES2667729T3
(es)
|
2007-09-26 |
2018-05-14 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
WO2009126616A2
(en)
|
2008-04-07 |
2009-10-15 |
Zymogenetics, Inc. |
Thrombin activator compostions and methods of making and using the same
|
|
CA2731435A1
(en)
|
2008-07-21 |
2010-01-28 |
Arstasis, Inc. |
Devices, methods, and kits for forming tracts in tissue
|
|
US20100077498A1
(en)
|
2008-09-11 |
2010-03-25 |
Pardridge William M |
Compositions and methods for blood-brain barrier delivery in the mouse
|
|
TW201438738A
(zh)
*
|
2008-09-16 |
2014-10-16 |
Genentech Inc |
治療進展型多發性硬化症之方法
|
|
CN102164960A
(zh)
|
2008-09-26 |
2011-08-24 |
罗氏格黎卡特股份公司 |
双特异性抗-egfr/抗-igf-1r抗体
|
|
US20100098693A1
(en)
|
2008-10-07 |
2010-04-22 |
Pardridge William M |
Compositions and methods for blood-brain barrier delivery of organophosphatases
|
|
US20130090457A1
(en)
|
2008-10-31 |
2013-04-11 |
Janssen Biotech, Inc. |
Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases
|
|
US8323649B2
(en)
|
2008-11-25 |
2012-12-04 |
Alderbio Holdings Llc |
Antibodies to IL-6 and use thereof
|
|
PE20160653A1
(es)
|
2009-03-05 |
2016-07-24 |
Abbvie Inc |
Proteinas de union a il-17
|
|
BRPI1014089A2
(pt)
|
2009-04-02 |
2016-04-19 |
Roche Glycart Ag |
anticorpos multiespecíficos que compreendem anticorpos de comprimento completo e fragmentos fab de cadeia simples
|
|
MX2011010158A
(es)
|
2009-04-07 |
2011-10-17 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-2/anti-c-met.
|
|
US8703132B2
(en)
*
|
2009-06-18 |
2014-04-22 |
Hoffmann-La Roche, Inc. |
Bispecific, tetravalent antigen binding proteins
|
|
WO2011066371A2
(en)
|
2009-11-24 |
2011-06-03 |
Alder Biopharmaceuticals, Inc. |
Antibodies to il-6 and use thereof
|
|
US9775921B2
(en)
|
2009-11-24 |
2017-10-03 |
Alderbio Holdings Llc |
Subcutaneously administrable composition containing anti-IL-6 antibody
|
|
FR2953841B1
(fr)
|
2009-12-16 |
2011-12-30 |
Centre Nat Rech Scient |
Anticorps diriges contre le recepteur de la transferrine et leurs utilisations pour l'immunotherapie des tumeurs qui dependent du fer
|
|
WO2011116387A1
(en)
*
|
2010-03-19 |
2011-09-22 |
Tetragenetics, Inc. |
Production of aglycosylated monoclonal antibodies in ciliates
|
|
EP2558494B1
(en)
|
2010-04-15 |
2018-05-23 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
|
RU2439160C1
(ru)
|
2010-06-25 |
2012-01-10 |
Государственное общеобразовательное учреждение высшего профессионального образования "Российский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО РГМУ Росздрава) |
Способ получения моноклональных антител к аблюминальному мембранному антигену церебральных эндотелиоцитов
|
|
TW201206473A
(en)
*
|
2010-08-03 |
2012-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
EA034333B1
(ru)
|
2010-11-30 |
2020-01-29 |
Дженентек, Инк. |
Варианты антитела для переноса соединения через гематоэнцефалический барьер
|
|
WO2012075340A2
(en)
|
2010-12-01 |
2012-06-07 |
Alderbio Holdings Llc |
Anti-ngf compositions and use thereof
|
|
WO2012087835A2
(en)
|
2010-12-22 |
2012-06-28 |
Boston Biomedical Research Institute |
Compositions and methods for enhancing protein folding
|
|
WO2012088247A2
(en)
|
2010-12-22 |
2012-06-28 |
Medimmune, Llc |
Anti-c5/c5a/c5adesr antibodies and fragments
|
|
MX2013007936A
(es)
|
2011-01-06 |
2013-08-09 |
Glaxo Group Ltd |
Ligandos que se unen al receptor ii del factor de crecimiento transformante-beta.
|
|
JP2014506258A
(ja)
*
|
2011-01-10 |
2014-03-13 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
新規使用
|
|
AU2012222833B2
(en)
|
2011-03-03 |
2017-03-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
|
KR20160044598A
(ko)
|
2011-03-29 |
2016-04-25 |
로슈 글리카트 아게 |
항체 Fc 변이체
|
|
BR112013026306A2
(pt)
|
2011-04-20 |
2017-09-05 |
Roche Glycart Ag |
MÉTODO E CONSTRUTOS PARA A PASSAGEM DE PENDENTE DO pH DA BARREIRA SANGUE-CÉREBRO
|
|
JP5980202B2
(ja)
|
2011-05-09 |
2016-08-31 |
株式会社ペルセウスプロテオミクス |
トランスフェリン受容体を特異的に認識できる抗体
|
|
WO2013006244A1
(en)
|
2011-06-08 |
2013-01-10 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
Bispecific monoclonal antibody therapeutics against west nile virus with improved cns penetration
|
|
WO2013009471A1
(en)
|
2011-07-08 |
2013-01-17 |
Lubrigreen Biosynthetics, Llc |
Compositions and products containing estolide compounds
|
|
WO2013012733A1
(en)
*
|
2011-07-15 |
2013-01-24 |
Biogen Idec Ma Inc. |
Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
|
|
MX2014001766A
(es)
|
2011-08-17 |
2014-05-01 |
Genentech Inc |
Anticuerpos de neuregulina y sus usos.
|
|
PT2748201T
(pt)
*
|
2011-08-23 |
2018-02-08 |
Roche Glycart Ag |
Moléculas de ligação ao antigénio biespecíficas que ativam as células t
|
|
JP5925893B2
(ja)
|
2011-08-23 |
2016-05-25 |
ロシュ グリクアート アーゲー |
二重特異性抗原結合分子
|
|
CA2855955A1
(en)
|
2011-09-12 |
2013-03-21 |
Janssen Biotech, Inc. |
Toll-like receptor 3 antagonists
|
|
WO2013038156A1
(en)
|
2011-09-16 |
2013-03-21 |
Ucb Pharma S.A. |
Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile
|
|
US11851476B2
(en)
*
|
2011-10-31 |
2023-12-26 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain
|
|
EP2785375B1
(en)
|
2011-11-28 |
2020-07-22 |
Merck Patent GmbH |
Anti-pd-l1 antibodies and uses thereof
|
|
RU2693264C2
(ru)
|
2012-02-03 |
2019-07-01 |
Ф.Хоффман-Ля Рош Аг |
Молекулы биспецифических антител и т-клетки, трансфецированные антигеном, и их применение в медицине
|
|
JP2015508664A
(ja)
|
2012-02-29 |
2015-03-23 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
カラムでの酵素的切断
|
|
NZ626955A
(en)
|
2012-03-08 |
2016-01-29 |
Hoffmann La Roche |
Abeta antibody formulation
|
|
PE20142422A1
(es)
|
2012-04-05 |
2015-01-21 |
Hoffmann La Roche |
Anticuerpos biespecificos contra tweak humana e il 17 humana y usos de los mismos
|
|
EA201491920A1
(ru)
|
2012-05-21 |
2016-03-31 |
Дженентек, Инк. |
Способы повышения безопасности транспорта через гематоэнцефалический барьер
|
|
EP2668901A1
(en)
|
2012-05-31 |
2013-12-04 |
Roche Diagniostics GmbH |
Sensor insertion assembly, sensor cartridge, and inserter
|
|
US9438547B2
(en)
|
2012-07-10 |
2016-09-06 |
Microsoft Technology Licensing, Llc |
Uniform policy for security and information protection
|
|
US9382329B2
(en)
*
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
CA2879496C
(en)
*
|
2012-08-29 |
2024-01-09 |
F. Hoffmann-La Roche Ag |
Blood brain barrier shuttle
|
|
MX2015002947A
(es)
|
2012-09-07 |
2015-09-23 |
Genentech Inc |
Terapia de combinacion de un anticuerpo ant-cd20 tipo ii con un inhibidor blc-2 selectivo.
|
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
|
WO2014059442A2
(en)
|
2012-10-12 |
2014-04-17 |
Arizona Board Agents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University |
Antibody based reagents that specifically recognize toxic oligomeric forms of tau
|
|
UY35148A
(es)
*
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
KR102545617B1
(ko)
*
|
2012-11-28 |
2023-06-20 |
자임워크스 비씨 인코포레이티드 |
가공된 면역글로불린 중쇄-경쇄 쌍 및 이들의 용도
|
|
CA2890455A1
(en)
|
2012-12-04 |
2014-06-12 |
Abbvie, Inc. |
Blood-brain barrier (bbb) penetrating dual specific binding proteins
|
|
RU2015140915A
(ru)
|
2013-02-26 |
2017-04-03 |
Роше Гликарт Аг |
Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
|
|
WO2014131711A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
JP2016519081A
(ja)
|
2013-03-14 |
2016-06-30 |
バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ |
ヘパリンと結合体化した抗トロンビンβに対するモノクローナル抗体
|
|
US9732150B2
(en)
|
2013-03-14 |
2017-08-15 |
Alderbio Holdings Llc |
Therapeutic use of antibodies to HGF
|
|
US9481725B2
(en)
|
2013-03-14 |
2016-11-01 |
Alderbio Holdings, Llc |
Antibodies to HGF and compositions containing
|
|
EP2970985A1
(en)
|
2013-03-14 |
2016-01-20 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to modify cells for therapeutic objectives
|
|
DE102013208865A1
(de)
|
2013-05-14 |
2014-11-20 |
Beiersdorf Ag |
Stabilisierte Zubereitungen mit einem Gehalt an Ascorbinsäure und Phosphationen
|
|
EP4324480A3
(en)
*
|
2013-05-20 |
2024-05-08 |
F. Hoffmann-La Roche AG |
Anti-transferrin receptor antibodies and methods of use
|
|
PE20160720A1
(es)
|
2013-08-02 |
2016-07-28 |
Hoffmann La Roche |
Proteina de fusion terapeutica
|
|
RU2016115866A
(ru)
|
2013-10-11 |
2017-11-16 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифические антитела с обменянными доменами и одинаковыми вариабельными доменами легкой цепи
|
|
BR112016009919A2
(pt)
|
2013-11-04 |
2017-12-05 |
Glenmark Pharmaceuticals Sa |
imunoglobulina hetero-dimérica ou fragmento da mesma e método para produzir in vitro uma imunoglobulina hetero-dimérica ou fragmento da mesma
|
|
HK1222803A1
(zh)
|
2013-11-07 |
2017-07-14 |
豪夫迈．罗氏有限公司 |
抗cd20抗体与btk抑制剂的组合疗法
|
|
CA2924268C
(en)
|
2013-11-21 |
2021-05-18 |
F. Hoffmann-La Roche Ag |
Anti-alpha-synuclein antibodies and methods of use
|
|
KR102357961B1
(ko)
|
2013-12-17 |
2022-02-08 |
제넨테크, 인크. |
항-cd3 항체 및 이의 사용 방법
|
|
US10370692B2
(en)
|
2013-12-20 |
2019-08-06 |
Hoffmann-La Roche Inc. |
Recombinant polypeptide production methods
|
|
BR112016015589A2
(pt)
|
2014-01-06 |
2017-10-31 |
Hoffmann La Roche |
módulos de trânsito monovalentes para a barreira hematoencefálica
|
|
US9629801B2
(en)
|
2014-01-10 |
2017-04-25 |
Wisconsin Alumni Research Foundation |
Blood-brain barrier targeting antibodies
|
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
|
KR102411972B1
(ko)
|
2014-08-04 |
2022-06-23 |
에프. 호프만-라 로슈 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
|
CN116333153A
(zh)
|
2014-11-26 |
2023-06-27 |
森科股份有限公司 |
结合cd3和肿瘤抗原的异二聚体抗体
|
|
WO2016160032A1
(en)
|
2015-04-03 |
2016-10-06 |
Entropic Communications, Inc. |
Low power adc with pulsed bias
|
|
US20160297581A1
(en)
|
2015-04-13 |
2016-10-13 |
Aplix Inc |
Closable container
|
|
CN107531788B
(zh)
|
2015-06-24 |
2022-06-21 |
豪夫迈·罗氏有限公司 |
对her2和血脑屏障受体特异性的三特异性抗体及使用方法
|
|
IL302486A
(en)
|
2015-06-24 |
2023-06-01 |
Hoffmann La Roche |
Antibodies against the transnephrine receptor with adapted affinity
|
|
EA039366B1
(ru)
|
2015-06-24 |
2022-01-19 |
Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. |
Антитело к рецептору трансферрина человека, проникающее через гематоэнцефалический барьер
|
|
JP6657392B2
(ja)
|
2015-10-02 |
2020-03-04 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗ヒトｃｄ２０／ヒトトランスフェリン受容体抗体及び使用方法
|
|
AR106189A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
|
|
JP2017187722A
(ja)
|
2016-04-08 |
2017-10-12 |
株式会社リコー |
画像濃度検出装置及び画像形成装置
|
|
SG11201908127WA
(en)
*
|
2017-03-10 |
2019-10-30 |
Hoffmann La Roche |
Method for producing multispecific antibodies
|