CL2012002012A1 - Anticuerpo anti-cd38 o fragmento de este, capaz de destruir una célula cd38+ por apoptosis, citotoxicidad celular adcc y citotoxicidad cdc; anticuerpo humanizado; polinucleótido, vector y célula huésped que lo codifican; conjugado del anticuerpo con un compuesto citotóxico; composición farmacéutica con dichos anticuerpos; uso de los anticuerpos para tratar cáncer o enfermedad autoinmune; método para diagnosticar cáncer. - Google Patents
Anticuerpo anti-cd38 o fragmento de este, capaz de destruir una célula cd38+ por apoptosis, citotoxicidad celular adcc y citotoxicidad cdc; anticuerpo humanizado; polinucleótido, vector y célula huésped que lo codifican; conjugado del anticuerpo con un compuesto citotóxico; composición farmacéutica con dichos anticuerpos; uso de los anticuerpos para tratar cáncer o enfermedad autoinmune; método para diagnosticar cáncer.Info
- Publication number
- CL2012002012A1 CL2012002012A1 CL2012002012A CL2012002012A CL2012002012A1 CL 2012002012 A1 CL2012002012 A1 CL 2012002012A1 CL 2012002012 A CL2012002012 A CL 2012002012A CL 2012002012 A CL2012002012 A CL 2012002012A CL 2012002012 A1 CL2012002012 A1 CL 2012002012A1
- Authority
- CL
- Chile
- Prior art keywords
- antibody
- antibodies
- cell
- cytotoxicity
- cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 230000003013 cytotoxicity Effects 0.000 title abstract 4
- 231100000135 cytotoxicity Toxicity 0.000 title abstract 4
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 2
- 230000006907 apoptotic process Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 231100000433 cytotoxic Toxicity 0.000 title abstract 2
- 230000001472 cytotoxic effect Effects 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title abstract 2
- 229940127121 immunoconjugate Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 abstract 1
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 abstract 1
- 230000010056 antibody-dependent cellular cytotoxicity Effects 0.000 abstract 1
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Abstract
Anticuerpo anti-CD38 O fragmento de éste, capaz de destruir una célula CD38+ por apoptosis, citotoxicidad celular ADCC y citotoxicidad CDC; anticuerpo humanizado; polinucleótido, vector y célula huésped que lo codifican; conjugado del anticuerpo con un compuesto citotóxico; composición farmacéutica con dichos anticuerpos; uso de los anticuerpos para tratar cáncer o enfermedad autoinmune; método para diagnosticar cáncer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06291628A EP1914242A1 (en) | 2006-10-19 | 2006-10-19 | Novel anti-CD38 antibodies for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012002012A1 true CL2012002012A1 (es) | 2012-11-05 |
Family
ID=37831721
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200702995A CL2007002995A1 (es) | 2006-10-19 | 2007-10-18 | Anticuerpo o fragmento anti-cd38; dicho anticuerpo humanizado; conjugado del anticuerpo con un compuesto citotoxico; composicion farmaceutica con dichos anticuerpos; uso de los anticuerpos para tratar cancer o enfermedad autoinmune; metodo para diagn |
| CL2012002012A CL2012002012A1 (es) | 2006-10-19 | 2012-07-19 | Anticuerpo anti-cd38 o fragmento de este, capaz de destruir una célula cd38+ por apoptosis, citotoxicidad celular adcc y citotoxicidad cdc; anticuerpo humanizado; polinucleótido, vector y célula huésped que lo codifican; conjugado del anticuerpo con un compuesto citotóxico; composición farmacéutica con dichos anticuerpos; uso de los anticuerpos para tratar cáncer o enfermedad autoinmune; método para diagnosticar cáncer. |
| CL2017001580A CL2017001580A1 (es) | 2006-10-19 | 2017-06-16 | Anticuerpo o fragmento de anticuerpo contra cd38 anticuerpo humanizado, conjugado del anticuerpo con un compuesto citotoxico composición farmacéutica con dichos anticuerpos uso de los anticuerpos para tratar cáncer o enfermedad autoinmune método para diagnosticar cáncer polinucleotido vector y célula huésped. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200702995A CL2007002995A1 (es) | 2006-10-19 | 2007-10-18 | Anticuerpo o fragmento anti-cd38; dicho anticuerpo humanizado; conjugado del anticuerpo con un compuesto citotoxico; composicion farmaceutica con dichos anticuerpos; uso de los anticuerpos para tratar cancer o enfermedad autoinmune; metodo para diagn |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2017001580A CL2017001580A1 (es) | 2006-10-19 | 2017-06-16 | Anticuerpo o fragmento de anticuerpo contra cd38 anticuerpo humanizado, conjugado del anticuerpo con un compuesto citotoxico composición farmacéutica con dichos anticuerpos uso de los anticuerpos para tratar cáncer o enfermedad autoinmune método para diagnosticar cáncer polinucleotido vector y célula huésped. |
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