CL2011000845A1 - Uso de dl-metionil-dl-metionina y sus sales como aditivo para productos alimenticios para animales mantenidos en cultivos marinos; mezcla de alimentos que lo comprende; procedimiento para la preparacion de dl-metionil-dl-metionina; procedimiento para la aislacion de la mezcla de diasteromeros de dd/ll/dl/ld- metionilmetionina y procedimiento para la disociacion de la mezcla de diasteromeros de dd/ll/dl/ld-metionilmetionina. - Google Patents
Uso de dl-metionil-dl-metionina y sus sales como aditivo para productos alimenticios para animales mantenidos en cultivos marinos; mezcla de alimentos que lo comprende; procedimiento para la preparacion de dl-metionil-dl-metionina; procedimiento para la aislacion de la mezcla de diasteromeros de dd/ll/dl/ld- metionilmetionina y procedimiento para la disociacion de la mezcla de diasteromeros de dd/ll/dl/ld-metionilmetionina.Info
- Publication number
- CL2011000845A1 CL2011000845A1 CL2011000845A CL2011000845A CL2011000845A1 CL 2011000845 A1 CL2011000845 A1 CL 2011000845A1 CL 2011000845 A CL2011000845 A CL 2011000845A CL 2011000845 A CL2011000845 A CL 2011000845A CL 2011000845 A1 CL2011000845 A1 CL 2011000845A1
- Authority
- CL
- Chile
- Prior art keywords
- methionine
- methionylmethionine
- mixture
- diasteromers
- methionyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- 235000013305 food Nutrition 0.000 title abstract 4
- 241001465754 Metazoa Species 0.000 title abstract 2
- 239000000654 additive Substances 0.000 title abstract 2
- 230000000996 additive effect Effects 0.000 title abstract 2
- 238000010494 dissociation reaction Methods 0.000 title abstract 2
- 230000005593 dissociations Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- ZYTPOUNUXRBYGW-UHFFFAOYSA-N methionyl-methionine Chemical compound CSCCC(N)C(=O)NC(C(O)=O)CCSC ZYTPOUNUXRBYGW-UHFFFAOYSA-N 0.000 title 2
- 238000002955 isolation Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 239000004470 DL Methionine Substances 0.000 abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 3
- 230000009466 transformation Effects 0.000 abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000009413 insulation Methods 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- Marine Sciences & Fisheries (AREA)
- Insects & Arthropods (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCIÓN SE REFIERE AL USO DE DL-METIONINA-DL-METIONINA Y SALES DE LA MISMA COMO ADITIVO DE PRODUCTOS ALIMENTICIOS PARA ANIMALES MANTENIDOS EN CULTIVOS MARINOS, MEZCLAS DE PRODUCTOS ALIMENTICIOS QUE LA COMPRENDE Y PROCEDIMIENTOS PARA LA PREPARACIÓN DE DL-METIONIL-DL- METIONINA (I) CON LA FORMULA<br /> QUE SE LLEVA A CABO MEDIANTE TRANSFORMACIÓN DE UN DERIVADO DE UREA DE LA FORMULA GENERAL II (II) DONDE LOS RESTOS R1 Y R2 EN LOS DERIVADOS DE UREA LLA, IIB, IIC, LID, LIE, IIF Y IIG SON LO DEFINIDO EN EL PLIEGO DE REIVINDICACIONES.E DEFINEN EIERON DE LA SIGUIENTE MANERA:<br /> EN DL-METIONIL-DL-METIONINA, EN DONDE METIONINHIDANTOLNA SE UTILIZA COMO PRODUCTO DE PARTIDA O SE FORMA COMO INTERMEDIARIO Y UNA SOLUCIÓN QUE CONTIENE METIONINHIDANTOINA Y AGUA ES TRANSFORMADA CON METIONINA EN CONDICIONES BÁSICAS, SIENDO EL VALOR DE PH DE LA SOLUCIÓN QUE CONTIENE EL DERIVADO DE LA UREA AJUSTADO A UN VALOR DE 8 A 14, DE PREFERENCIA A UN VALOR DE 10 A 13 Y DONDE LA TRANSFORMACION SE REALIZA A UNA TEMPERATURA DE 50 A 200"C, DE PREFERENCIA A UNA TEMPERATURA DE 80 A 170°C Y DE PREFERENCIA ESPECIAL A UNA TEMPERATURA DE 130 A 160"C, BAJO PRESIÓN.<br /> TAMBIÉN SE REVELAN PROCEDIMIENTOS PARA LA AISLACIÓN DE LA MEZCLA DE DIASTEREOMEROS DE DD/LL/DL/LD-METIONILMETIONINA MEDIANTE CRISTALIZACIÓN DE SOLUCIONES DE REACCIÓN ÁCIDAS Y BÁSICAS PROCEDIMIENTOS PARA LA DISOCIACIÓN DE LA MEZCLA DE DIASTEREOMEROS DE DD/LL/DL/LD-METIONILMETIONINA MEDIANTE CRISTALIZACIÓN FRACCIONADA, EN DONDE SE OBTIENEN LOS DOS PARES DE ENANTIÓMEROS DD/LL/DL/LD-METIONILMETIONINA Y DL/LD-METIONILMETIONINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008042932A DE102008042932A1 (de) | 2008-10-17 | 2008-10-17 | Herstellung und Verwendung von Methionylmethionin als Futtermitteladditiv für Fische und Krustentiere |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011000845A1 true CL2011000845A1 (es) | 2011-08-26 |
Family
ID=41396092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011000845A CL2011000845A1 (es) | 2008-10-17 | 2011-04-15 | Uso de dl-metionil-dl-metionina y sus sales como aditivo para productos alimenticios para animales mantenidos en cultivos marinos; mezcla de alimentos que lo comprende; procedimiento para la preparacion de dl-metionil-dl-metionina; procedimiento para la aislacion de la mezcla de diasteromeros de dd/ll/dl/ld- metionilmetionina y procedimiento para la disociacion de la mezcla de diasteromeros de dd/ll/dl/ld-metionilmetionina. |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US8968817B2 (es) |
| EP (1) | EP2348881B1 (es) |
| JP (2) | JP5693457B2 (es) |
| CN (4) | CN101720858A (es) |
| BR (1) | BRPI0920882B1 (es) |
| CA (1) | CA2740663C (es) |
| CL (1) | CL2011000845A1 (es) |
| DE (1) | DE102008042932A1 (es) |
| ES (1) | ES2437602T3 (es) |
| MX (1) | MX2011003946A (es) |
| MY (1) | MY155599A (es) |
| PL (1) | PL2348881T3 (es) |
| RU (1) | RU2599783C2 (es) |
| WO (1) | WO2010043558A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7704521B2 (en) * | 2007-04-11 | 2010-04-27 | Zinpro Corporation | Rumen protected essential amino acids |
| DE102008042932A1 (de) | 2008-10-17 | 2010-04-22 | Evonik Degussa Gmbh | Herstellung und Verwendung von Methionylmethionin als Futtermitteladditiv für Fische und Krustentiere |
| CA2993690C (en) | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| EA035287B1 (ru) | 2011-07-21 | 2020-05-25 | ДСМ АйПи АССЕТС Б.В. | Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения |
| WO2013119955A1 (en) | 2012-02-09 | 2013-08-15 | Novus International Inc. | Functionalized polymer compositions |
| CN107753462B (zh) | 2012-07-12 | 2021-01-08 | 诺华丝国际股份有限公司 | 用于保护生物活性剂的基质和层组合物 |
| US20160122701A1 (en) * | 2013-02-01 | 2016-05-05 | Carnegie Mellon University | Methods, Devices and Systems for Algae Lysis and Content Extraction |
| DE102013215434A1 (de) | 2013-08-06 | 2015-02-12 | Evonik Industries Ag | Methionyl-Methionin-Stereoisomere und deren Verwendung in Kosmetika |
| WO2015198247A1 (en) * | 2014-06-24 | 2015-12-30 | John O'halloran | Fish feed compositions containing a neonicotinoid for preventing and treating parasite infections |
| DE102014225211A1 (de) * | 2014-12-09 | 2016-06-09 | Henkel Ag & Co. Kgaa | Leistungsstarke kosmetische Mittel mit Proteolipid und einem Dipeptid |
| US20180194804A1 (en) * | 2015-07-09 | 2018-07-12 | Evonik Degussa Gmbh | Simplified and scalable method for synthesis of 2,6-bis(methionyl)- 1,4-diketopiperazine |
| EP3339289A1 (de) * | 2016-12-21 | 2018-06-27 | Evonik Degussa GmbH | Verfahren zur herstellung von methionin |
| US10266512B2 (en) | 2017-08-10 | 2019-04-23 | Novus International, Inc. | Processes for preparing heteroatom containing cyclic dimers |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| CN109485589B (zh) * | 2018-11-09 | 2022-02-11 | 天宝动物营养科技股份有限公司 | 一种含碳酸钾或碳酸氢钾的蛋氨酸母液制备蛋氨酸锌螯合物的方法 |
| CN111323522B (zh) * | 2020-04-22 | 2022-01-04 | 中国海洋大学 | 一种食品中白鲢成分的鉴真方法及应用 |
| EP4023637A1 (de) * | 2020-12-30 | 2022-07-06 | Evonik Operations GmbH | Verfahren zur diastereomerenreinen herstellung von dl/ld-methionyl-methionin |
| EP4023662A1 (de) | 2020-12-30 | 2022-07-06 | Evonik Operations GmbH | Verfahren zur erzeugung von partikelförmigem methionyl-methionin |
| CN113896667A (zh) * | 2021-09-27 | 2022-01-07 | 湖北泓肽生物科技有限公司 | 羟基蛋氨酸-蛋氨酸二肽类似物及其制备方法和应用 |
| WO2023067059A1 (en) | 2021-10-20 | 2023-04-27 | Evonik Operations Gmbh | Process for producing dl-methionine and dlld-methionylmethionine |
| WO2023067061A1 (en) | 2021-10-20 | 2023-04-27 | Evonik Operations Gmbh | Precursors for the preparation of dl-methionine and dlld-methionylmethionine |
| WO2023180282A1 (en) | 2022-03-24 | 2023-09-28 | Evonik Operations Gmbh | Co-precipitates of methionylmethionine with organic compounds |
| CN114685603A (zh) * | 2022-05-07 | 2022-07-01 | 宁夏紫光天化蛋氨酸有限责任公司 | 蛋氨酰蛋氨酸的制备方法 |
| EP4286399A1 (en) | 2022-06-03 | 2023-12-06 | Evonik Operations GmbH | Recovery of methionylmethionine from aqueous alkali metal ions containing media |
| EP4299581A1 (de) | 2022-06-30 | 2024-01-03 | Evonik Operations GmbH | Verfahren zur herstellung von dl-methionin und zur diastereomerenreinen herstellung von dlld-methionyl-methionin |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1059323A (en) * | 1962-09-11 | 1967-02-15 | Ass Elect Ind | Improvements relating to waveguide shutters |
| JPS4931792B1 (es) * | 1966-08-11 | 1974-08-24 | ||
| US3657423A (en) * | 1970-11-18 | 1972-04-18 | Amburgo Co Inc The | Chicken feed composition containing fly ash for weight gain |
| DE2261926C3 (de) | 1972-12-18 | 1978-11-30 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Verfahren zur Herstellung von DL-Methionyl-DL-methionin |
| CH589047A5 (es) * | 1972-10-23 | 1977-06-30 | Degussa | |
| DE2251877C3 (de) * | 1972-10-23 | 1981-01-08 | Degussa Ag, 6000 Frankfurt | Lebensmittel- und Futtermittelzusatzstoff |
| DE2430617C2 (de) * | 1974-06-26 | 1987-01-15 | Degussa Ag, 6000 Frankfurt | Verfahren zur Herstellung von 3,6-Bis- (2-Methylmercaptoäthyl)-2,5-piperazindion |
| US4235942A (en) * | 1979-02-22 | 1980-11-25 | Standard Oil Company (Indiana) | Digestible polyamino acids |
| DE3335218A1 (de) * | 1983-09-29 | 1985-04-11 | Degussa Ag, 6000 Frankfurt | Verfahren zur hydrolyse von 5-(ss-methylmercaptoethyl) -hydantoin |
| US4608257A (en) * | 1984-01-03 | 1986-08-26 | Board Of Regents For Oklahoma State University | Composition and method for treating heat stress |
| JPH01191650A (ja) * | 1988-01-23 | 1989-08-01 | Kyowa Hakko Kogyo Co Ltd | 養魚用飼料 |
| DE4235295A1 (de) * | 1992-10-20 | 1994-04-21 | Degussa | Kontinuierlich durchführbares Verfahren zur Herstellung von Methionin oder Methioninderivaten |
| JPH0731380A (ja) * | 1993-07-17 | 1995-02-03 | Central Res Inst Of Electric Power Ind | ヒラメの養殖方法およびその飼料 |
| JPH09241227A (ja) * | 1996-03-08 | 1997-09-16 | Ajinomoto Co Inc | 新規光学分割剤 |
| JP3620243B2 (ja) * | 1996-10-31 | 2005-02-16 | 住友化学株式会社 | メチオニンの製造方法 |
| DE19822099A1 (de) * | 1998-05-16 | 1999-11-18 | Degussa | Verfahren zur Herstellung von wäßrigen Natriummethioninat-Lösungen und Verwendung dieser Lösungen zur Herstellung eines Granulats |
| JP2001231461A (ja) * | 2000-02-28 | 2001-08-28 | San Baiorekkusu:Kk | 魚介類用飼料添加剤およびこれを含む魚介類用飼料 |
| WO2002088667A2 (en) | 2001-05-02 | 2002-11-07 | Novus International, Inc. | ENANTIOSELECTIVE OLIGOMERIZATION OF α-HYDROXY CARBOXYLIC ACIDS AND α-AMINO ACIDS |
| US20030099689A1 (en) | 2001-08-31 | 2003-05-29 | Ohio State Research Foundation | Dietary formulations including peptides |
| WO2003045904A1 (en) * | 2001-11-29 | 2003-06-05 | Nippon Soda Co.,Ltd. | Process for production of methionine |
| EP1413573A1 (en) * | 2002-10-24 | 2004-04-28 | Adisseo France S.A.S. | Process for the production of 3-methylthiopropanal |
| JP2004175715A (ja) * | 2002-11-27 | 2004-06-24 | Nippon Soda Co Ltd | メチオニンの晶析方法 |
| ES2365849T3 (es) * | 2004-02-14 | 2011-10-11 | Evonik Degussa Gmbh | Procedimiento para producir metionina. |
| JP4997729B2 (ja) * | 2005-08-29 | 2012-08-08 | 住友化学株式会社 | メチオニンの製造方法 |
| DE102006055470A1 (de) * | 2006-11-24 | 2008-05-29 | Evonik Degussa Gmbh | Ketomethioninketale und deren Derivate |
| DE102007031917A1 (de) * | 2007-07-09 | 2009-01-15 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Ketosäuren und deren Derivaten |
| DE102007062199A1 (de) * | 2007-12-21 | 2009-06-25 | Evonik Degussa Gmbh | 2-Methylthioethyl-substituierte Heterocyclen als Futtermitteladditive |
| DE102008042932A1 (de) | 2008-10-17 | 2010-04-22 | Evonik Degussa Gmbh | Herstellung und Verwendung von Methionylmethionin als Futtermitteladditiv für Fische und Krustentiere |
| DE102009002044A1 (de) | 2009-03-31 | 2010-10-07 | Evonik Degussa Gmbh | Dipeptide als Futtermitteladditive |
| DE102010029399A1 (de) | 2010-05-27 | 2011-12-01 | Evonik Degussa Gmbh | Cyclische Dipeptide als Futtermitteladditive |
-
2008
- 2008-10-17 DE DE102008042932A patent/DE102008042932A1/de not_active Withdrawn
-
2009
- 2009-03-23 CN CN200910128896A patent/CN101720858A/zh active Pending
- 2009-10-09 MX MX2011003946A patent/MX2011003946A/es active IP Right Grant
- 2009-10-09 MY MYPI2011001656A patent/MY155599A/en unknown
- 2009-10-09 ES ES09737390.6T patent/ES2437602T3/es active Active
- 2009-10-09 RU RU2011119472/04A patent/RU2599783C2/ru not_active IP Right Cessation
- 2009-10-09 JP JP2011531453A patent/JP5693457B2/ja not_active Expired - Fee Related
- 2009-10-09 PL PL09737390T patent/PL2348881T3/pl unknown
- 2009-10-09 CN CN201510390203.0A patent/CN105061555B/zh active Active
- 2009-10-09 EP EP09737390.6A patent/EP2348881B1/de active Active
- 2009-10-09 WO PCT/EP2009/063160 patent/WO2010043558A1/de not_active Ceased
- 2009-10-09 BR BRPI0920882-8A patent/BRPI0920882B1/pt active IP Right Grant
- 2009-10-09 CN CN200980141377.6A patent/CN102186358B/zh active Active
- 2009-10-09 CA CA2740663A patent/CA2740663C/en not_active Expired - Fee Related
- 2009-10-09 CN CN201510390212.XA patent/CN105053577B/zh active Active
- 2009-10-16 US US12/580,283 patent/US8968817B2/en active Active
-
2011
- 2011-04-15 CL CL2011000845A patent/CL2011000845A1/es unknown
-
2012
- 2012-09-14 US US13/616,341 patent/US9095161B2/en active Active
- 2012-09-14 US US13/616,533 patent/US9078459B2/en active Active
-
2014
- 2014-05-26 JP JP2014108562A patent/JP6033254B2/ja active Active
-
2015
- 2015-04-21 US US14/691,813 patent/US20150223495A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9095161B2 (en) | 2015-08-04 |
| CA2740663C (en) | 2017-01-17 |
| US20150223495A1 (en) | 2015-08-13 |
| JP2012505646A (ja) | 2012-03-08 |
| CN102186358A (zh) | 2011-09-14 |
| CN101720858A (zh) | 2010-06-09 |
| MY155599A (en) | 2015-11-13 |
| JP2014193176A (ja) | 2014-10-09 |
| EP2348881A1 (de) | 2011-08-03 |
| RU2011119472A (ru) | 2013-03-20 |
| BRPI0920882A2 (pt) | 2017-02-21 |
| WO2010043558A1 (de) | 2010-04-22 |
| US20130011514A1 (en) | 2013-01-10 |
| US20100098801A1 (en) | 2010-04-22 |
| CN105061555B (zh) | 2019-07-30 |
| MX2011003946A (es) | 2011-05-19 |
| CN105061555A (zh) | 2015-11-18 |
| CN102186358B (zh) | 2015-06-03 |
| US9078459B2 (en) | 2015-07-14 |
| CA2740663A1 (en) | 2010-04-22 |
| EP2348881B1 (de) | 2013-09-04 |
| JP5693457B2 (ja) | 2015-04-01 |
| US20130008384A1 (en) | 2013-01-10 |
| US8968817B2 (en) | 2015-03-03 |
| CN105053577B (zh) | 2019-05-07 |
| ES2437602T3 (es) | 2014-01-13 |
| CN105053577A (zh) | 2015-11-18 |
| JP6033254B2 (ja) | 2016-11-30 |
| PL2348881T3 (pl) | 2014-03-31 |
| DE102008042932A1 (de) | 2010-04-22 |
| BRPI0920882B1 (pt) | 2018-04-10 |
| RU2599783C2 (ru) | 2016-10-20 |
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