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CL2008003261A1 - Composición farmaceutica en forma de suspension que comprende carisbamato, hipromelosa y agua; proceso para prepararla y su uso para tratar enfermedades tales como epilepsia, dolor neuropatico, temblor y esquizofrenia, entre otras. - Google Patents

Composición farmaceutica en forma de suspension que comprende carisbamato, hipromelosa y agua; proceso para prepararla y su uso para tratar enfermedades tales como epilepsia, dolor neuropatico, temblor y esquizofrenia, entre otras.

Info

Publication number
CL2008003261A1
CL2008003261A1 CL2008003261A CL2008003261A CL2008003261A1 CL 2008003261 A1 CL2008003261 A1 CL 2008003261A1 CL 2008003261 A CL2008003261 A CL 2008003261A CL 2008003261 A CL2008003261 A CL 2008003261A CL 2008003261 A1 CL2008003261 A1 CL 2008003261A1
Authority
CL
Chile
Prior art keywords
carisbamate
hypromellose
tremor
schizophrenia
epilepsy
Prior art date
Application number
CL2008003261A
Other languages
English (en)
Inventor
Roger EMBRECHTS
Leersnijder Cedric De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40386492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008003261(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2008003261A1 publication Critical patent/CL2008003261A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composición farmacéutica en forma de suspensión que comprende carisbamato, hipromelosa, agua, un agente de suspensión, un agente humectante, uno o varios conservantes, un buffer, un endulzante y un saborizante, proceso para prepararla y su uso para tratar enfermedades, tales como, epilepsia, dolor neuropático, temblor y esquizofrenia, entre otras.
CL2008003261A 2007-10-31 2008-10-30 Composición farmaceutica en forma de suspension que comprende carisbamato, hipromelosa y agua; proceso para prepararla y su uso para tratar enfermedades tales como epilepsia, dolor neuropatico, temblor y esquizofrenia, entre otras. CL2008003261A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98414407P 2007-10-31 2007-10-31

Publications (1)

Publication Number Publication Date
CL2008003261A1 true CL2008003261A1 (es) 2009-10-16

Family

ID=40386492

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003261A CL2008003261A1 (es) 2007-10-31 2008-10-30 Composición farmaceutica en forma de suspension que comprende carisbamato, hipromelosa y agua; proceso para prepararla y su uso para tratar enfermedades tales como epilepsia, dolor neuropatico, temblor y esquizofrenia, entre otras.

Country Status (26)

Country Link
US (4) US8263652B2 (es)
EP (1) EP2214637B1 (es)
JP (3) JP5841333B2 (es)
KR (1) KR101568681B1 (es)
CN (2) CN104840971A (es)
AR (1) AR069125A1 (es)
AU (1) AU2008320458B2 (es)
BR (1) BRPI0818118B8 (es)
CA (1) CA2703971C (es)
CL (1) CL2008003261A1 (es)
CO (1) CO6270300A2 (es)
CR (1) CR11550A (es)
EA (1) EA019881B1 (es)
EC (1) ECSP10010208A (es)
ES (1) ES2432666T3 (es)
IL (1) IL205352A (es)
MX (1) MX2010004889A (es)
MY (1) MY154063A (es)
NI (1) NI201000076A (es)
PA (1) PA8801901A1 (es)
PE (1) PE20090951A1 (es)
PL (1) PL2214637T3 (es)
TW (1) TW200934531A (es)
UY (1) UY31444A1 (es)
WO (1) WO2009056980A1 (es)
ZA (1) ZA201003848B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263652B2 (en) * 2007-10-31 2012-09-11 Sk Biopharmaceuticals Co., Ltd. Stabilized pediatric suspension of carisbamate
WO2011107855A2 (en) 2010-03-04 2011-09-09 Torrent Pharmaceuticals Limited Sustained release oral liquid suspension dosage form
HRP20150105T1 (hr) * 2010-04-30 2015-03-13 Bristol-Myers Squibb Company Farmaceutske kompozicije koje sadrže n-(4-(2-amino-3-hloropiridin-4-iloksi)-3-fluorofenil-l-(4-fluorofenil)-2-okso-1,2-dihidropiridin-3-karboksamid
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
JO3190B1 (ar) * 2011-10-19 2018-03-08 Otsuka Pharma Co Ltd محلول للتناول عن طريق الفم
TWI660748B (zh) * 2013-03-01 2019-06-01 日商大塚製藥股份有限公司 用於口服投藥之包含非晶型托伐普坦（Ｔｏｌｖａｐｔａｎ）的懸浮液
CN103966680A (zh) * 2014-05-04 2014-08-06 东华大学 一种药物缓释纳米纤维的制备方法
TW201717929A (zh) * 2015-05-22 2017-06-01 愛思開生物製藥股份有限公司 包括卡立胺酯之藥物及其於預防、緩解或治療疼痛或癲癎之用途
ITUB20155193A1 (it) * 2015-11-03 2017-05-03 Italfarmaco Spa Sospensioni orali di Givinostat fisicamente e chimicamente stabili
CN105997866B (zh) * 2016-07-13 2019-08-20 成都明慈医药科技有限公司 一种含地塞米松的混悬剂及其制备方法
US10336679B2 (en) * 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
KR102369827B1 (ko) 2020-09-04 2022-03-04 (주)피알지에스앤텍 프로게리닌을 포함하는 나노현탁액 및 이의 제조방법
US20220213802A1 (en) * 2021-01-06 2022-07-07 General Electric Company System for controlling blade clearances within a gas turbine engine
KR102686558B1 (ko) 2022-01-25 2024-07-22 (주)피알지에스앤텍 프로게리닌을 포함하는 과립제 및 이를 이용한 샤셋제

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265728A (en) 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
HUT77362A (hu) * 1994-10-14 1998-03-30 Janssen Pharmaceutica N.V. Sabeluzolt tartalmazó vizes orális szuszpenziók és eljárás előállításukra
US5698588A (en) 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
AU782759B2 (en) * 1999-08-20 2005-08-25 Ortho-Mcneil Pharmaceutical, Inc. Composition comprising a tramadol material and an anticonvulsant drug
CZ20032311A3 (cs) * 2001-02-27 2005-02-16 Ortho-Mcneil Pharmaceutical, Inc. Karbamátová sloučenina a léčivo pro prevenci a léčení úzkosti
KR100803796B1 (ko) * 2003-06-17 2008-02-14 화이자 인코포레이티드 세로토닌 및 노르아드레날린 재흡수 억제제로서의ｎ-피롤리딘-3-일-아미드 유도체
WO2008021666A2 (en) * 2006-08-18 2008-02-21 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
JP2010506846A (ja) * 2006-10-13 2010-03-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ フェニルアルキルカルバメート組成物
US8263652B2 (en) * 2007-10-31 2012-09-11 Sk Biopharmaceuticals Co., Ltd. Stabilized pediatric suspension of carisbamate

Also Published As

Publication number Publication date
TW200934531A (en) 2009-08-16
ECSP10010208A (es) 2010-06-29
BRPI0818118B1 (pt) 2020-05-12
EP2214637A1 (en) 2010-08-11
BRPI0818118A2 (pt) 2015-08-04
US20170112798A1 (en) 2017-04-27
MY154063A (en) 2015-04-30
US20160008476A1 (en) 2016-01-14
CA2703971A1 (en) 2009-05-07
ES2432666T3 (es) 2013-12-04
BRPI0818118B8 (pt) 2021-05-25
ZA201003848B (en) 2011-08-31
CO6270300A2 (es) 2011-04-20
CR11550A (es) 2011-01-14
CN101848699A (zh) 2010-09-29
JP2014193913A (ja) 2014-10-09
CA2703971C (en) 2017-10-10
PL2214637T3 (pl) 2013-10-31
US20120309826A1 (en) 2012-12-06
KR20100092944A (ko) 2010-08-23
PE20090951A1 (es) 2009-07-13
NI201000076A (es) 2010-11-10
US8263652B2 (en) 2012-09-11
EA019881B1 (ru) 2014-07-30
JP5841333B2 (ja) 2016-01-13
JP2016216486A (ja) 2016-12-22
MX2010004889A (es) 2010-05-19
US9161913B2 (en) 2015-10-20
CN104840971A (zh) 2015-08-19
UY31444A1 (es) 2009-04-30
AU2008320458A1 (en) 2009-05-07
US10201519B2 (en) 2019-02-12
IL205352A0 (en) 2010-12-30
KR101568681B1 (ko) 2015-11-12
EA201070534A1 (ru) 2010-12-30
WO2009056980A1 (en) 2009-05-07
AU2008320458B2 (en) 2014-01-23
JP2011500870A (ja) 2011-01-06
IL205352A (en) 2014-09-30
US20090111872A1 (en) 2009-04-30
EP2214637B1 (en) 2013-05-08
PA8801901A1 (es) 2009-06-23
JP6273589B2 (ja) 2018-02-07
AR069125A1 (es) 2009-12-30

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