CA2762819A1 - Systeme de cassette rotative pour inhalateur de poudre seche - Google Patents
Systeme de cassette rotative pour inhalateur de poudre seche Download PDFInfo
- Publication number
- CA2762819A1 CA2762819A1 CA2762819A CA2762819A CA2762819A1 CA 2762819 A1 CA2762819 A1 CA 2762819A1 CA 2762819 A CA2762819 A CA 2762819A CA 2762819 A CA2762819 A CA 2762819A CA 2762819 A1 CA2762819 A1 CA 2762819A1
- Authority
- CA
- Canada
- Prior art keywords
- inhaler
- blister pack
- dry powder
- blister
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940112141 dry powder inhaler Drugs 0.000 title claims description 16
- 239000003814 drug Substances 0.000 claims abstract description 58
- 230000033001 locomotion Effects 0.000 claims abstract description 22
- 229940079593 drug Drugs 0.000 claims description 41
- 239000000843 powder Substances 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 5
- 230000004913 activation Effects 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 description 13
- 239000002775 capsule Substances 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 3
- 210000002345 respiratory system Anatomy 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000004067 bulking agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000012254 powdered material Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229960002052 salbutamol Drugs 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/06—Containers or packages with special means for dispensing contents for dispensing powdered or granular material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/001—Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0063—Storages for pre-packed dosages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0075—Mechanical counters having a display or indicator on a disc
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0294—Piezoelectric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/587—Lighting arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Mechanical Engineering (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Basic Packing Technique (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Moulding By Coating Moulds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18039609P | 2009-05-21 | 2009-05-21 | |
| US61/180,396 | 2009-05-21 | ||
| PCT/US2010/035817 WO2010135672A1 (fr) | 2009-05-21 | 2010-05-21 | Système de cassette rotative pour inhalateur de poudre sèche |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2762819A1 true CA2762819A1 (fr) | 2010-11-25 |
| CA2762819C CA2762819C (fr) | 2016-12-20 |
Family
ID=43123719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2762819A Expired - Fee Related CA2762819C (fr) | 2009-05-21 | 2010-05-21 | Systeme de cassette rotative pour inhalateur de poudre seche |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8763606B2 (fr) |
| EP (1) | EP2432536B1 (fr) |
| JP (2) | JP5752679B2 (fr) |
| KR (1) | KR101585707B1 (fr) |
| CN (1) | CN102438685B (fr) |
| AU (1) | AU2010249402B2 (fr) |
| BR (1) | BRPI1011194A2 (fr) |
| CA (1) | CA2762819C (fr) |
| CL (1) | CL2011002900A1 (fr) |
| EA (1) | EA026215B1 (fr) |
| ES (1) | ES2682996T3 (fr) |
| MX (1) | MX2011012265A (fr) |
| MY (1) | MY159925A (fr) |
| NZ (1) | NZ596564A (fr) |
| PE (1) | PE20121146A1 (fr) |
| WO (1) | WO2010135672A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110167618A (zh) * | 2016-12-09 | 2019-08-23 | 微计量医疗公司 | 吸入器 |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2761559B2 (ja) | 1989-11-13 | 1998-06-04 | 株式会社アドバンテスト | 半導体メモリ試験用データ発生装置 |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| AU2003220125B2 (en) | 2002-03-20 | 2006-06-15 | Mannkind Corporation | Inhalation apparatus |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| EP2314298B1 (fr) | 2004-08-23 | 2015-05-27 | MannKind Corporation | Microparticules comprenant des sels de diketopiperazine permettant l'administration de médicaments |
| AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
| DK1986679T3 (da) | 2006-02-22 | 2017-11-20 | Mannkind Corp | Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof |
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| WO2009079078A1 (fr) | 2007-12-14 | 2009-06-25 | Labogroup S.A.S. | Administration de produits alimentaires sous forme d'aérosols |
| CN103252007B (zh) | 2008-06-13 | 2016-06-22 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| JP5479465B2 (ja) | 2008-06-20 | 2014-04-23 | マンカインド コーポレイション | 吸入努力をリアルタイムにプロファイルする対話式機器および方法 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2676695A3 (fr) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Appareil, système et procédé de mesure de résistance d'un inhalateur |
| US8985101B2 (en) * | 2009-05-21 | 2015-03-24 | Microdose Therapeutx, Inc. | Method and device for clamping a blister within a dry powder inhaler |
| KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| WO2011056889A1 (fr) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | Appareil et méthode de simulation d'efforts d'inhalation |
| CN105381524A (zh) | 2010-01-05 | 2016-03-09 | 微剂量治疗技术公司 | 吸入设备和方法 |
| RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
| BR112013007371A2 (pt) * | 2010-09-30 | 2016-07-12 | Novartis Ag | inalador. |
| CA3114582A1 (fr) | 2010-12-22 | 2012-06-28 | Syqe Medical Ltd. | Procede et systeme d'administration de medicament |
| EP2756835B1 (fr) * | 2011-01-14 | 2019-11-27 | Yuyama Mfg. Co., Ltd. | Cassette de comprimés |
| CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
| WO2012174472A1 (fr) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | Microparticules de dicétopipérazine de capacité élevée |
| WO2013063160A1 (fr) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Procédés et compositions pour traiter la douleur |
| SG11201500218VA (en) | 2012-07-12 | 2015-03-30 | Mannkind Corp | Dry powder drug delivery systems and methods |
| EP2911690A1 (fr) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Compositions et procédés de vaccin antigrippal inhalable |
| EP2970149B1 (fr) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Compositions de dicétopipérazine microcristallines et procédés |
| CN105451716A (zh) | 2013-07-18 | 2016-03-30 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
| WO2015021064A1 (fr) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Appareil d'insufflation et procédés |
| USD804015S1 (en) * | 2013-12-23 | 2017-11-28 | Glenmark Pharmaceuticals Limited | Inhaler |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| WO2016001921A2 (fr) | 2014-06-30 | 2016-01-07 | Syqe Medical Ltd. | Procédé et dispositif utilisables en vue de la vaporisation et de l'inhalation de substances isolées |
| IL273507B2 (en) | 2014-06-30 | 2024-06-01 | Syqe Medical Ltd | Methods, devices and systems for administering active substances through the lungs |
| US11298477B2 (en) | 2014-06-30 | 2022-04-12 | Syqe Medical Ltd. | Methods, devices and systems for pulmonary delivery of active agents |
| PL3160565T3 (pl) | 2014-06-30 | 2022-01-10 | Syqe Medical Ltd. | Urządzenia i systemy do dopłucnego dostarczania środków aktywnych |
| CN106604755B (zh) | 2014-06-30 | 2020-08-11 | Syqe医药有限公司 | 流量调节的吸入器装置 |
| KR102561375B1 (ko) * | 2014-06-30 | 2023-08-01 | 사이키 메디컬 엘티디. | 흡입기용 투약 카트리지를 클램핑하기 위한 클램핑 챔버 |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| TWI597079B (zh) | 2015-04-10 | 2017-09-01 | 微劑量醫療公司 | 泡殼帶進給機構 |
| CN108144168A (zh) * | 2015-05-16 | 2018-06-12 | 苏州汉方医药有限公司 | 一种手动悬浮微颗粒发生器与化学药物制剂组成的治疗药盒 |
| JP6818008B2 (ja) | 2015-07-20 | 2021-01-20 | パール セラピューティクス，インコーポレイテッド | エアロゾル送達システムおよび関連する方法 |
| MX2018005336A (es) * | 2015-10-30 | 2018-05-17 | Johnson & Johnson Consumer Inc | Nebulizador de aerosol aseptico de dosis unitaria. |
| JP6957454B2 (ja) | 2015-11-06 | 2021-11-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザと容器とを有するシステム |
| ES2874087T3 (es) | 2016-01-06 | 2021-11-04 | Syqe Medical Ltd | Tratamiento terapéutico con dosis bajas |
| CA169756S (en) | 2016-02-08 | 2017-09-01 | Nicoventures Holdings Ltd | Electronic cigarette |
| EP3419708B1 (fr) * | 2016-02-24 | 2019-11-20 | Boehringer Ingelheim International GmbH | Inhalateur |
| GB201605100D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Vapour provision system |
| GB201605105D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Vapour provision apparatus |
| GB201605101D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Electronic vapour provision system |
| GB201605102D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Mechanical connector for electronic vapour provision system |
| JP2019516485A (ja) | 2016-05-19 | 2019-06-20 | マンカインド コーポレイション | 吸入を検出および監視するための機器、システム、および方法 |
| RU2741664C2 (ru) | 2016-07-22 | 2021-01-28 | Никовенчерс Трейдинг Лимитед | Футляр для устройства предоставления пара |
| WO2018071427A1 (fr) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhalateur et ses méthodes d'utilisation |
| TR201803793A2 (tr) * | 2018-03-16 | 2018-06-21 | Inofab Saglik Teknolojileri Anonim Sirketi | İnhalatör eklenti̇si̇ |
| DE102020100551A1 (de) * | 2019-01-14 | 2020-07-16 | Alfred Von Schuckmann | Vorrichtung zum Inhalieren pulverförmiger Substanzen |
| DE102020100550A1 (de) * | 2019-01-14 | 2020-07-16 | Alfred Von Schuckmann | Vorrichtung zum Inhalieren pulverförmiger Substanzen, Substanzbehälter für eine solche Vorrichtung sowie Verfahren zum Befüllen einer derartigen Vorrichtung |
| CN119607338B (zh) * | 2024-12-25 | 2025-07-22 | 杭州畅溪制药有限公司 | 一种干粉吸入器械 |
Family Cites Families (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2517482A (en) | 1949-04-09 | 1950-08-01 | Sharp & Dohme Inc | Inhaler |
| GB1182779A (en) | 1966-09-17 | 1970-03-04 | Fisons Pharmaceuticals Ltd | Inhalation Device |
| US3507277A (en) | 1966-09-17 | 1970-04-21 | Fisons Pharmaceuticals Ltd | Inhalation device |
| GB1268051A (en) | 1968-06-07 | 1972-03-22 | Fisons Pharmaceuticals Ltd | Inhalation device |
| US3653380A (en) | 1970-02-16 | 1972-04-04 | American Cyanamid Co | Aerosol powder dosage dispensing device |
| US3831606A (en) | 1971-02-19 | 1974-08-27 | Alza Corp | Auto inhaler |
| IT941426B (it) | 1971-07-17 | 1973-03-01 | Isf Spa | Inalatore a camera di turbinio per sostanze medicamentose polveriformi |
| US3795244A (en) | 1973-02-02 | 1974-03-05 | Syntex Corp | Inhalation device |
| YU41046B (en) | 1974-08-22 | 1986-10-31 | Schering Ag | Medicine inholating device |
| US3948264A (en) | 1975-05-21 | 1976-04-06 | Mead Johnson & Company | Inhalation device |
| US4094317A (en) | 1976-06-11 | 1978-06-13 | Wasnich Richard D | Nebulization system |
| ZA811942B (en) | 1980-03-25 | 1983-02-23 | H Malem | Nebulising apparatus |
| ES286422Y (es) * | 1982-10-08 | 1986-09-16 | Glaxo Group Limited | Dispositivo para administrar medicamentos a pacientes |
| US5260321A (en) | 1984-11-12 | 1993-11-09 | Sandoz Ltd. | Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins |
| US4733797A (en) | 1986-09-22 | 1988-03-29 | Haber Terry M | Dosage sealing, monitoring and dispensing assembly |
| IT1228460B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore monouso con capsula pre-forata |
| GB8909891D0 (en) | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
| US5110008A (en) | 1989-09-29 | 1992-05-05 | Moulding Jr Thomas S | Dispenser adapted to isolate the dispensed objects by compression between two moveable structures |
| MY105368A (en) | 1990-03-02 | 1994-09-30 | Glaxo Group Ltd | Inhalation device. |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| SK280967B6 (sk) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Inhalačný prístroj |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| GB9021433D0 (en) | 1990-10-02 | 1990-11-14 | Atomic Energy Authority Uk | Power inhaler |
| US6629646B1 (en) | 1991-04-24 | 2003-10-07 | Aerogen, Inc. | Droplet ejector with oscillating tapered aperture |
| CA2112674C (fr) | 1991-07-02 | 2005-10-04 | John S. Patton | Methode et instrument pour la delivrance de medicaments en aerosol |
| DE69327733T2 (de) | 1992-10-16 | 2000-08-10 | Sheiman Ultrasonic Research Foundation Pty. Ltd., Sydney | Ultraschall-vernebelungsvorrichtung |
| US5429302A (en) | 1993-05-19 | 1995-07-04 | Fisons Corporation | Nebulizing element and device |
| US5709202A (en) * | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| US5349947A (en) | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
| US5727546A (en) | 1993-08-18 | 1998-03-17 | Fisons Plc | Powder inhaler with breath flow regulation valve |
| AU3002495A (en) * | 1994-06-30 | 1996-01-25 | Minnesota Mining And Manufacturing Company | Cure-indicating molding and coating composition |
| DK0778758T3 (da) * | 1994-08-30 | 1999-06-21 | Pharmacia & Upjohn Ab | Fremgangsmåde til fremstilling af en dirigeret strøm af små dråber |
| US5503869A (en) * | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
| US5758823A (en) | 1995-06-12 | 1998-06-02 | Georgia Tech Research Corporation | Synthetic jet actuator and applications thereof |
| US6457654B1 (en) | 1995-06-12 | 2002-10-01 | Georgia Tech Research Corporation | Micromachined synthetic jet actuators and applications thereof |
| US6209538B1 (en) | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
| US5647357A (en) | 1995-09-08 | 1997-07-15 | Respironics, Inc. | Respiratory mask facial seal |
| US5694920A (en) | 1996-01-25 | 1997-12-09 | Abrams; Andrew L. | Inhalation device |
| US6026809A (en) * | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
| US6312909B1 (en) | 1996-03-29 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Compositions and methods for the diagnosis prevention and treatment of tumor progression |
| US5699649A (en) | 1996-07-02 | 1997-12-23 | Abrams; Andrew L. | Metering and packaging device for dry powders |
| US5906202A (en) | 1996-11-21 | 1999-05-25 | Aradigm Corporation | Device and method for directing aerosolized mist to a specific area of the respiratory tract |
| GB9626263D0 (en) | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| SE9700424D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Powder inhaler |
| US5823434A (en) | 1997-05-05 | 1998-10-20 | The United States Of America As Represented By The Secretary Of The Navy | Electromechanical driver for an aerosol dispensing apparatus which dispenses a medicated vapor into the lungs of a patient |
| US6237590B1 (en) | 1997-09-18 | 2001-05-29 | Delsys Pharmaceutical Corporation | Dry powder delivery system apparatus |
| US6152130A (en) | 1998-06-12 | 2000-11-28 | Microdose Technologies, Inc. | Inhalation device with acoustic control |
| US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
| GB2343122B (en) | 1998-10-26 | 2003-01-08 | Medic Aid Ltd | Improvements in and relating to nebulisers |
| US6070575A (en) | 1998-11-16 | 2000-06-06 | Aradigm Corporation | Aerosol-forming porous membrane with certain pore structure |
| US6328033B1 (en) | 1999-06-04 | 2001-12-11 | Zohar Avrahami | Powder inhaler |
| NZ521051A (en) | 2000-02-11 | 2003-07-25 | Profile Respiratory Systems Lt | Drug delivery apparatus |
| US8820316B2 (en) | 2000-02-11 | 2014-09-02 | Respironics Respiratory Drug Delivery (Uk) Ltd | Drug delivery apparatus |
| DE10011120A1 (de) | 2000-03-09 | 2001-09-13 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
| PL201275B1 (pl) * | 2000-03-10 | 2009-03-31 | Univ North Carolina | Inhalator suchego proszku |
| US6971383B2 (en) * | 2001-01-24 | 2005-12-06 | University Of North Carolina At Chapel Hill | Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods |
| US6759159B1 (en) | 2000-06-14 | 2004-07-06 | The Gillette Company | Synthetic jet for admitting and expelling reactant air |
| US7080644B2 (en) | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
| US6622720B2 (en) | 2000-12-18 | 2003-09-23 | Xerox Corporation | Using capillary wave driven droplets to deliver a pharmaceutical product |
| US6546927B2 (en) | 2001-03-13 | 2003-04-15 | Aerogen, Inc. | Methods and apparatus for controlling piezoelectric vibration |
| AU2002327052B2 (en) | 2001-09-06 | 2007-10-18 | Microdose Therapeutx, Inc. | Adaptors for inhalers to improve performance |
| WO2003024514A1 (fr) | 2001-09-19 | 2003-03-27 | Advent Pharmaceuticals Pty Ltd | Inhaleur |
| US6722581B2 (en) | 2001-10-24 | 2004-04-20 | General Electric Company | Synthetic jet actuators |
| SE524990C2 (sv) | 2002-04-12 | 2004-11-09 | Microdrug Ag | Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver |
| SE524957C2 (sv) | 2002-04-12 | 2004-11-02 | Microdrug Ag | Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament |
| JP4740589B2 (ja) | 2002-04-29 | 2011-08-03 | グラクソ グループ リミテッド | 警告システム |
| US6889690B2 (en) | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
| JP4425795B2 (ja) | 2002-06-27 | 2010-03-03 | オリエル・セラピューティクス，インコーポレイテッド | 乾燥粉末の分注方法およびシステム |
| GB0217196D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicament dispenser |
| US6962266B2 (en) | 2002-10-04 | 2005-11-08 | Ecolab Inc. | Method and apparatus for using a unit dose dispenser |
| GB2395437C (en) | 2002-11-20 | 2010-10-20 | Profile Respiratory Systems Ltd | Improved inhalation method and apparatus |
| JP2006522634A (ja) | 2003-04-14 | 2006-10-05 | ベクトゥラ・リミテッド | 投与効率を向上させるデバイス及び製薬組成 |
| EP1468748A1 (fr) | 2003-04-15 | 2004-10-20 | Microflow Engineering SA | Générateur de gouttelettes de liquide et sa buse |
| US8545463B2 (en) | 2003-05-20 | 2013-10-01 | Optimyst Systems Inc. | Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device |
| GB0315509D0 (en) * | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| GB2407042B (en) | 2003-10-17 | 2007-10-24 | Vectura Ltd | Inhaler |
| US7377277B2 (en) * | 2003-10-27 | 2008-05-27 | Oriel Therapeutics, Inc. | Blister packages with frames and associated methods of fabricating dry powder drug containment systems |
| US7451761B2 (en) | 2003-10-27 | 2008-11-18 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances |
| SE0303269L (sv) | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| KR101315690B1 (ko) | 2003-12-03 | 2013-10-22 | 베링거 인겔하임 인터내셔날 게엠베하 | 습기 민감성 의약용 기-계량된 건조 분말 흡입기 |
| SE0303570L (sv) | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
| WO2005072803A1 (fr) | 2004-01-16 | 2005-08-11 | Biodel, Inc. | Dispositif d'administration sublinguale de medicaments |
| US7607435B2 (en) | 2004-01-21 | 2009-10-27 | Battelle Memorial Institute | Gas or liquid flow sensor |
| US7538473B2 (en) | 2004-02-03 | 2009-05-26 | S.C. Johnson & Son, Inc. | Drive circuits and methods for ultrasonic piezoelectric actuators |
| WO2005076872A2 (fr) | 2004-02-06 | 2005-08-25 | Microdose Technologies, Inc. | Emballage-coque a utiliser avec un dispositif d'inhalation |
| MXPA06009516A (es) * | 2004-02-24 | 2007-03-26 | Microdose Technologies Inc | Inhalador con sensor de flujo direccional. |
| CN100589849C (zh) | 2004-02-24 | 2010-02-17 | 微计量技术有限公司 | 基于合成射流的药物输送方法和装置 |
| DE102005005540B4 (de) | 2005-02-07 | 2007-10-04 | Pari GmbH Spezialisten für effektive Inhalation | In verschiedenen Moden ansteuerbare Inhalationstherapievorrichtung |
| GB0518355D0 (en) * | 2005-09-08 | 2005-10-19 | Glaxo Group Ltd | An inhaler |
| AU2007210177C1 (en) * | 2006-01-31 | 2012-11-01 | Oriel Therapeutics, Inc. | Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods |
| BRPI0708109A2 (pt) | 2006-02-20 | 2011-05-17 | Boehringer Ingelheim Int | inalador |
| SG170835A1 (en) * | 2006-04-05 | 2011-05-30 | Microdose Therapeutx Inc | Variable dose inhalation device |
| US8196576B2 (en) * | 2007-02-28 | 2012-06-12 | Microdose Therapeutx, Inc. | Inhaler |
| US20100252032A1 (en) | 2007-07-06 | 2010-10-07 | Boehringer Ingelheim International Gmbh | Inhaler |
| US8297280B2 (en) | 2007-07-20 | 2012-10-30 | Canon Kabushiki Kaisha | Inhaler |
| US8196579B2 (en) * | 2007-08-29 | 2012-06-12 | Smiths Medical Asd, Inc. | Nose cannula heated/humidified gas delivery system |
| GB0800709D0 (en) | 2008-01-16 | 2008-02-20 | Dunne Stephen T | Double jet impinging nozzle |
| CN103252007B (zh) | 2008-06-13 | 2016-06-22 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| DE102009005048A1 (de) | 2009-01-13 | 2010-07-15 | Borm, Hans-Jürgen | Verfahren und Einrichtung zur automatischen Ermittlung eines inspiratorischen Leckagevolumens bei der maschinellen Beatmung |
-
2010
- 2010-05-21 MY MYPI2011005573A patent/MY159925A/en unknown
- 2010-05-21 ES ES10778482.9T patent/ES2682996T3/es active Active
- 2010-05-21 JP JP2012512067A patent/JP5752679B2/ja not_active Expired - Fee Related
- 2010-05-21 US US12/785,082 patent/US8763606B2/en not_active Expired - Fee Related
- 2010-05-21 KR KR1020117030462A patent/KR101585707B1/ko not_active Expired - Fee Related
- 2010-05-21 MX MX2011012265A patent/MX2011012265A/es active IP Right Grant
- 2010-05-21 NZ NZ596564A patent/NZ596564A/xx unknown
- 2010-05-21 EA EA201171452A patent/EA026215B1/ru not_active IP Right Cessation
- 2010-05-21 WO PCT/US2010/035817 patent/WO2010135672A1/fr not_active Ceased
- 2010-05-21 PE PE2011001991A patent/PE20121146A1/es not_active Application Discontinuation
- 2010-05-21 BR BRPI1011194A patent/BRPI1011194A2/pt not_active Application Discontinuation
- 2010-05-21 CA CA2762819A patent/CA2762819C/fr not_active Expired - Fee Related
- 2010-05-21 AU AU2010249402A patent/AU2010249402B2/en not_active Ceased
- 2010-05-21 CN CN201080022180.3A patent/CN102438685B/zh not_active Expired - Fee Related
- 2010-05-21 EP EP10778482.9A patent/EP2432536B1/fr not_active Not-in-force
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2011
- 2011-11-18 CL CL2011002900A patent/CL2011002900A1/es unknown
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- 2014-06-03 JP JP2014114763A patent/JP5804583B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110167618A (zh) * | 2016-12-09 | 2019-08-23 | 微计量医疗公司 | 吸入器 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010249402B2 (en) | 2014-08-21 |
| EA201171452A1 (ru) | 2012-05-30 |
| BRPI1011194A2 (pt) | 2016-12-27 |
| JP5752679B2 (ja) | 2015-07-22 |
| KR101585707B1 (ko) | 2016-01-14 |
| JP2014193390A (ja) | 2014-10-09 |
| CN102438685A (zh) | 2012-05-02 |
| EP2432536A1 (fr) | 2012-03-28 |
| PE20121146A1 (es) | 2012-08-27 |
| US20100294278A1 (en) | 2010-11-25 |
| AU2010249402A1 (en) | 2011-12-15 |
| MX2011012265A (es) | 2012-04-11 |
| US8763606B2 (en) | 2014-07-01 |
| EP2432536A4 (fr) | 2015-12-23 |
| EP2432536B1 (fr) | 2018-07-04 |
| CL2011002900A1 (es) | 2012-09-07 |
| KR20120036873A (ko) | 2012-04-18 |
| MY159925A (en) | 2017-02-15 |
| ES2682996T3 (es) | 2018-09-24 |
| NZ596564A (en) | 2012-11-30 |
| JP2012527329A (ja) | 2012-11-08 |
| CN102438685B (zh) | 2014-07-02 |
| CA2762819C (fr) | 2016-12-20 |
| WO2010135672A1 (fr) | 2010-11-25 |
| JP5804583B2 (ja) | 2015-11-04 |
| EA026215B1 (ru) | 2017-03-31 |
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