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CA2587848A1 - Lipopeptides anti-infectieux - Google Patents

Lipopeptides anti-infectieux Download PDF

Info

Publication number
CA2587848A1
CA2587848A1 CA002587848A CA2587848A CA2587848A1 CA 2587848 A1 CA2587848 A1 CA 2587848A1 CA 002587848 A CA002587848 A CA 002587848A CA 2587848 A CA2587848 A CA 2587848A CA 2587848 A1 CA2587848 A1 CA 2587848A1
Authority
CA
Canada
Prior art keywords
amino
compound
formula
carbamoyl
protecting group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002587848A
Other languages
English (en)
Inventor
Dylan Christopher Alexander
Richard H. Baltz
Paul Brian
Marie-Francoise Coeffet-Le Gal
Sascha Doekel
Xiaowei He
Vidya Kulkarni
Christopher Leitheiser
Vivian Pak Woon Miao
Kien Trung Nguyen
Ian Barrie Parr
Daniel Ritz
Yanzhi Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cubist Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2587848A1 publication Critical patent/CA2587848A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002587848A 2004-11-12 2005-11-11 Lipopeptides anti-infectieux Abandoned CA2587848A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62705604P 2004-11-12 2004-11-12
US60/627,056 2004-11-12
US71070505P 2005-08-23 2005-08-23
US60/710,705 2005-08-23
PCT/US2005/040919 WO2006110185A2 (fr) 2004-11-12 2005-11-11 Lipopeptides anti-infectieux

Publications (1)

Publication Number Publication Date
CA2587848A1 true CA2587848A1 (fr) 2006-10-19

Family

ID=37087468

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002587848A Abandoned CA2587848A1 (fr) 2004-11-12 2005-11-11 Lipopeptides anti-infectieux

Country Status (10)

Country Link
EP (1) EP1814588A2 (fr)
JP (1) JP2008519848A (fr)
KR (1) KR20070086038A (fr)
AU (1) AU2005330517A1 (fr)
BR (1) BRPI0517830A (fr)
CA (1) CA2587848A1 (fr)
IL (1) IL183109A0 (fr)
NO (1) NO20072634L (fr)
RU (1) RU2007121705A (fr)
WO (1) WO2006110185A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2512396C2 (ru) * 2008-12-22 2014-04-10 Кьюбист Фармасьютикалз, Инк. Новые противобактериальные средства для лечения грамположительных инфекций
RU2013157188A (ru) * 2011-05-26 2015-07-10 Кьюбист Фармасьютикалз, Инк. Композиции св-183,315 и относящиеся к ним способы
KR101723649B1 (ko) * 2014-10-23 2017-04-06 서울대학교산학협력단 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도
CN113061164B (zh) * 2021-03-29 2023-01-10 四川大学 环脂肽类化合物及其在抗类风湿关节炎药物中的应用
WO2023152229A1 (fr) * 2022-02-09 2023-08-17 Teitur Trophics Aps Nouveaux peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001044271A2 (fr) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Nouveaux lipopeptides en tant qu'agents antibacteriens
KR20020063228A (ko) * 1999-12-15 2002-08-01 큐비스트 파마슈티컬즈 인코포레이티드 항균제로서 리포펩티드
US6911525B2 (en) * 1999-12-15 2005-06-28 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
EP1423137B1 (fr) * 2001-08-06 2009-04-29 Cubist Pharmaceuticals, Inc. Stereo-isomeres de lipopeptide, methodes de preparation afferentes et intermediaires utiles
EP1421097A4 (fr) * 2001-08-06 2005-07-06 Cubist Pharm Inc Compositions et procedes relatifs a la famille multigenique biosynthetique de la daptomycine

Also Published As

Publication number Publication date
NO20072634L (no) 2007-08-09
WO2006110185A3 (fr) 2007-10-25
AU2005330517A2 (en) 2006-10-19
KR20070086038A (ko) 2007-08-27
BRPI0517830A (pt) 2008-10-21
WO2006110185A2 (fr) 2006-10-19
RU2007121705A (ru) 2008-12-20
IL183109A0 (en) 2008-04-13
JP2008519848A (ja) 2008-06-12
EP1814588A2 (fr) 2007-08-08
AU2005330517A1 (en) 2006-10-19

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Legal Events

Date Code Title Description
FZDE Discontinued