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CA2334677A1 - Preparation de composes heteroaryle - Google Patents

Preparation de composes heteroaryle Download PDF

Info

Publication number
CA2334677A1
CA2334677A1 CA002334677A CA2334677A CA2334677A1 CA 2334677 A1 CA2334677 A1 CA 2334677A1 CA 002334677 A CA002334677 A CA 002334677A CA 2334677 A CA2334677 A CA 2334677A CA 2334677 A1 CA2334677 A1 CA 2334677A1
Authority
CA
Canada
Prior art keywords
mmol
tetrahydropyridine
tert
butoxycarbonyl
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002334677A
Other languages
English (en)
Inventor
Vincent Patrick Rocco
Daniel James Koch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2334677A1 publication Critical patent/CA2334677A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention porte sur des procédés de préparation de 4-hétéroaryl-1,2,3,6-tétrahydropyridines et de 4-hétéroarylpipéridines.
CA002334677A 1998-06-19 1999-06-16 Preparation de composes heteroaryle Abandoned CA2334677A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8984698P 1998-06-19 1998-06-19
US60/089,846 1998-06-19
PCT/US1999/013521 WO1999065896A1 (fr) 1998-06-19 1999-06-16 Preparation de composes heteroaryle

Publications (1)

Publication Number Publication Date
CA2334677A1 true CA2334677A1 (fr) 1999-12-23

Family

ID=22219868

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002334677A Abandoned CA2334677A1 (fr) 1998-06-19 1999-06-16 Preparation de composes heteroaryle

Country Status (5)

Country Link
EP (1) EP1087962A4 (fr)
JP (1) JP2002518386A (fr)
AU (1) AU4685699A (fr)
CA (1) CA2334677A1 (fr)
WO (1) WO1999065896A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7560563B2 (en) 2002-07-23 2009-07-14 Kuraray Co., Ltd. Process for producing 2-substituted pyridine derivative
GEP20094675B (en) 2003-07-24 2009-05-10 Euro Celtique Sa Heteroaryl- tetra-hydropiperidyl compounds useful for treating or preventing pain
EP2426120A1 (fr) * 2003-08-18 2012-03-07 Fujifilm Finechemicals Co., Ltd. Pyridyl-tétrahydropyridines et pyridyl-pipéridines et procédé de leur fabrication
PL2142529T3 (pl) 2007-04-27 2014-06-30 Purdue Pharma Lp Antagoniści trpv1 i ich zastosowania
CN103717594B (zh) 2011-06-22 2016-12-14 普渡制药公司 包含二羟基取代基的trpv1拮抗剂及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945160A (en) * 1988-11-22 1990-07-31 Warner-Lambert Company Preparation of certain 7-substituted quinolones
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
US6303627B1 (en) * 1998-06-19 2001-10-16 Eli Lilly And Company Inhibitors of serotonin reuptake

Also Published As

Publication number Publication date
EP1087962A4 (fr) 2001-10-04
AU4685699A (en) 2000-01-05
EP1087962A1 (fr) 2001-04-04
WO1999065896A1 (fr) 1999-12-23
JP2002518386A (ja) 2002-06-25

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Legal Events

Date Code Title Description
FZDE Discontinued