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CA2301981A1 - Biomolecules comprenant un peptide elastomere - Google Patents

Biomolecules comprenant un peptide elastomere Download PDF

Info

Publication number
CA2301981A1
CA2301981A1 CA002301981A CA2301981A CA2301981A1 CA 2301981 A1 CA2301981 A1 CA 2301981A1 CA 002301981 A CA002301981 A CA 002301981A CA 2301981 A CA2301981 A CA 2301981A CA 2301981 A1 CA2301981 A1 CA 2301981A1
Authority
CA
Canada
Prior art keywords
peptide
biomolecule
peptides
sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002301981A
Other languages
English (en)
Inventor
Herald Reiersen
Anthony Rees
Lars Korsnes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2301981A1 publication Critical patent/CA2301981A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention concerne des biomolécules contenant une séquence d'acides aminés qui y est introduite et comprenant un peptide élastomère pouvant se contracter de manière inductible et qui, lors d'une contraction ou d'une extension, modifie les propriétés ou les caractéristiques de la molécule dans laquelle il est introduit, notamment des biomolécules telles que des anticorps; l'invention concerne également des molécules d'acide nucléique codant ces biomolécules ainsi que l'utilisation de ces biomolécules.
CA002301981A 1997-08-29 1998-08-28 Biomolecules comprenant un peptide elastomere Abandoned CA2301981A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9718463.4 1997-08-29
GBGB9718463.4A GB9718463D0 (en) 1997-08-29 1997-08-29 Biomolecules
PCT/GB1998/002602 WO1999011661A1 (fr) 1997-08-29 1998-08-28 Biomolecules comprenant un peptide elastomere

Publications (1)

Publication Number Publication Date
CA2301981A1 true CA2301981A1 (fr) 1999-03-11

Family

ID=10818314

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002301981A Abandoned CA2301981A1 (fr) 1997-08-29 1998-08-28 Biomolecules comprenant un peptide elastomere

Country Status (11)

Country Link
EP (1) EP1009761A1 (fr)
JP (1) JP2001514263A (fr)
KR (1) KR20010023510A (fr)
CN (1) CN1276796A (fr)
AU (1) AU759080B2 (fr)
BR (1) BR9811421A (fr)
CA (1) CA2301981A1 (fr)
GB (1) GB9718463D0 (fr)
MX (1) MXPA00002111A (fr)
NZ (1) NZ503097A (fr)
WO (1) WO1999011661A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19960509A1 (de) * 1999-12-15 2001-07-12 Jan Kristian Krueger Nanoskalierte Funktionsschicht
US20020068304A1 (en) * 2000-06-23 2002-06-06 Urry Dan W. Bioelastomer nanomachines and biosensors
WO2002072631A2 (fr) 2001-03-14 2002-09-19 Dakocytomation Denmark A/S Nouvelles constructions de molecules mhc, methodes d'utilisation de ces constructions a des fins de diagnostic et de therapie et utilisations de molecules mhc
DE10155862A1 (de) * 2001-11-14 2003-05-28 Ipk Inst Fuer Pflanzengenetik Produktion von rekombinanten Antikörpern mittels Fusion mit Elastin-ähnlichen Peptiden
ES2779992T3 (es) * 2005-12-20 2020-08-21 Univ Duke Métodos y composiciones para suministrar agentes activos con propiedades farmacológicas potenciadas
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
EP2361930A3 (fr) 2007-03-26 2011-10-26 Dako Denmark A/S Multimeres du complexes peptide-cmh et leur utilisation dans des maladies infectieuses de borrelia
EP2167537A2 (fr) 2007-07-03 2010-03-31 Dako Denmark A/S Procedes compiles pour analyser et trier des echantillons
EP2197908A2 (fr) 2007-09-27 2010-06-23 Dako Denmark A/S Multimères cmh dans le diagnostic, le vaccin et le traitement de la tuberculose
JP5458344B2 (ja) * 2008-01-30 2014-04-02 旭化成株式会社 抗体固定化担体
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
WO2009158704A2 (fr) 2008-06-27 2009-12-30 Duke University Agents thérapeutiques comprenant des peptides de type élastine
US10722562B2 (en) 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (fr) 2008-10-02 2010-04-08 Dako Denmark A/S Vaccins moléculaires contre les maladies infectieuses
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
EP3898666A2 (fr) 2018-12-17 2021-10-27 Immudex ApS Panneau comprenant des multimères de borrelia cmh

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE108455T1 (de) * 1986-04-17 1994-07-15 Uab Research Foundation Segmentierte polypeptid-bioelastomere zur modulierung des elastizitaetsmoduls.
JPH01501755A (ja) * 1986-11-04 1989-06-22 シントロ　コーポレイション 合成ｄｎａの構成および大ポリペプチドの合成におけるその使用
WO1988009344A1 (fr) * 1987-05-21 1988-12-01 Creative Biomolecules, Inc. Proteines mutifonctionnelles a cible predeterminee
AU630643B2 (en) * 1988-11-09 1992-11-05 Protein Polymers Technologies, Inc. Functional recombinantly prepared synthetic protein polymer
ES2067150T3 (es) * 1990-03-27 1995-03-16 Bioelastics Res Ltd Sistema de suministro de drogas bioelastomericas.
US5939385A (en) * 1993-08-13 1999-08-17 Zymogenetics, Inc. Transglutaminase cross-linkable polypeptides and methods relating thereto

Also Published As

Publication number Publication date
BR9811421A (pt) 2000-08-22
NZ503097A (en) 2002-03-28
WO1999011661A1 (fr) 1999-03-11
EP1009761A1 (fr) 2000-06-21
JP2001514263A (ja) 2001-09-11
MXPA00002111A (es) 2010-06-01
GB9718463D0 (en) 1997-11-05
AU759080B2 (en) 2003-04-03
KR20010023510A (ko) 2001-03-26
CN1276796A (zh) 2000-12-13
AU8875598A (en) 1999-03-22

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