CA2288129A1 - Utilisation de particules de type viral en tant qu'adjuvants - Google Patents
Utilisation de particules de type viral en tant qu'adjuvants Download PDFInfo
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- CA2288129A1 CA2288129A1 CA002288129A CA2288129A CA2288129A1 CA 2288129 A1 CA2288129 A1 CA 2288129A1 CA 002288129 A CA002288129 A CA 002288129A CA 2288129 A CA2288129 A CA 2288129A CA 2288129 A1 CA2288129 A1 CA 2288129A1
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-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10123—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne des préparations adjuvantes qui contiennent des particules de type viral (VLP) incapables de se répliquer. On peut dériver les VLP à partir d'un virus quelconque parmi plusieurs virus; elles peuvent servir à renforcer la réaction immunologique à un antigène choisi, l'antigène étant différent des particules.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4526297P | 1997-05-01 | 1997-05-01 | |
| US60/045,262 | 1997-05-01 | ||
| PCT/US1998/008146 WO1998050071A1 (fr) | 1997-05-01 | 1998-04-22 | Utilisation de particules de type viral en tant qu'adjuvants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2288129A1 true CA2288129A1 (fr) | 1998-11-12 |
Family
ID=21936887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002288129A Abandoned CA2288129A1 (fr) | 1997-05-01 | 1998-04-22 | Utilisation de particules de type viral en tant qu'adjuvants |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0980257A1 (fr) |
| JP (1) | JP2002508748A (fr) |
| AU (1) | AU750702B2 (fr) |
| CA (1) | CA2288129A1 (fr) |
| WO (1) | WO1998050071A1 (fr) |
Families Citing this family (36)
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|---|---|---|---|---|
| DE69901377T2 (de) * | 1999-01-27 | 2003-01-02 | Idea Ag | Nichtinvasive Impfung durch die Haut |
| JP2003511420A (ja) | 1999-10-13 | 2003-03-25 | カイロン コーポレイション | タンパク質から細胞性免疫応答を得る方法 |
| US7094882B2 (en) | 2000-04-21 | 2006-08-22 | Yeda Research And Development Co. Ltd. | Growth factor which acts through erb b-4 rtk |
| EP2196217A1 (fr) * | 2001-09-14 | 2010-06-16 | Cytos Biotechnology AG | Emballage de substances immunostimulantes dans des particules similaires aux virus: procédés de production et utilisations |
| US9045727B2 (en) | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
| ATE489969T1 (de) * | 2002-06-20 | 2010-12-15 | Cytos Biotechnology Ag | Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung |
| US8101189B2 (en) | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
| CN1665528B (zh) * | 2002-07-05 | 2013-05-15 | 弗利亚生物技术公司 | 佐剂病毒颗粒 |
| EP2301573A1 (fr) | 2002-10-01 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Compositions anticancéreuses et contre les maladies infectieuses, et procédés d'utilisation correspondants |
| CN100560719C (zh) | 2003-03-26 | 2009-11-18 | 赛托斯生物技术公司 | Melan-a肽类似物-病毒样颗粒偶联物 |
| US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| WO2005094878A1 (fr) * | 2004-03-31 | 2005-10-13 | Genomidea Inc. | Composition ayant un effet anti-tumeur |
| US7862829B2 (en) * | 2004-07-09 | 2011-01-04 | University Of North Carolina At Chapel Hill | Viral adjuvants |
| BRPI0519026A2 (pt) * | 2004-12-13 | 2008-12-23 | Cytos Biotechnology Ag | arranjos de antÍgeno de il-15 e usos dos mesmos |
| ES2310062B1 (es) | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| AT502275B8 (de) * | 2005-08-08 | 2007-08-15 | Greenhills Biotechnology Res D | Immunantwort-induzierende zusammensetzungen |
| JP5484732B2 (ja) | 2005-12-14 | 2014-05-07 | サイトス バイオテクノロジー アーゲー | 過敏症の治療のための免疫賦活性核酸パッケージ粒子 |
| EP1797895A1 (fr) | 2005-12-16 | 2007-06-20 | Pevion Biotech Ltd. | Un système adjuvant comportant des virosomes et liposomes |
| KR101552227B1 (ko) | 2006-06-12 | 2015-09-10 | 사이토스 바이오테크놀로지 아게 | 올리고뉴클레오티드를 ｒｎａ 박테리오파지의 바이러스-유사 입자로 패키징하는 방법 |
| DK2601969T3 (en) | 2006-09-29 | 2016-04-18 | Takeda Vaccines Inc | Norovirus vaccine formulations |
| JP2010508860A (ja) * | 2006-11-15 | 2010-03-25 | フォリア バイオテック インコーポレイテッド | パパイヤモザイクウイルスに基づくインフルエンザ用ワクチン |
| US20100047264A1 (en) * | 2006-11-15 | 2010-02-25 | Folia Biotech Inc. | Immunogenic Affinity-Conjugated Antigen Systems Based on Papaya Mosaic Virus and Uses Thereof |
| AU2007333147B2 (en) | 2006-12-12 | 2013-12-19 | Kuros Us Llc | Oligonucleotides containing high concentrations of guanine monomers |
| MX2009007942A (es) * | 2007-01-26 | 2010-06-01 | Folia Biotech Inc | Vacunas basadas en virus del mosaico de la papaya contra salmonella typhi y otros patogenos enterobacterianos. |
| WO2008109686A2 (fr) * | 2007-03-05 | 2008-09-12 | Neurok Pharma Llc | Particules recombinantes de type du virus de l'hépatite c non infectieuses et leurs applications pharmaceutiques |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| SG184733A1 (en) | 2007-09-18 | 2012-10-30 | Ligocyte Pharmaceuticals Inc | Method of conferring a protective immune response to norovirus |
| ES2664753T3 (es) | 2007-12-07 | 2018-04-23 | Glaxosmithkline Biologicals Sa | Composiciones de inducción de respuestas inmunes |
| CN101952436B (zh) * | 2008-01-09 | 2013-03-13 | 建国大学校产学协力团 | 基于杆状病毒的疫苗 |
| GB2459436A (en) * | 2008-04-08 | 2009-10-28 | Henderson Morley Plc | Vaccine adjuvant |
| ES2588913T3 (es) | 2008-06-04 | 2016-11-07 | The Chemo-Sero-Therapeutic Research Institute | Uso de una partícula vírica de encefalitis japonesa como adyuvante |
| CA2733589C (fr) * | 2008-08-08 | 2021-07-13 | Ligocyte Pharmaceuticals, Inc. | Particules similaires a un virus comportant des sequences d'acides amines de capside composites pour une reactivite croisee amelioree |
| WO2010059689A2 (fr) * | 2008-11-18 | 2010-05-27 | Ligocyte Pharmaceuticals, Inc. | Vlp rsv f et procédés de fabrication et d'utilisation de celui-ci |
| EP2447277A1 (fr) | 2010-10-28 | 2012-05-02 | Laboratorios Del. Dr. Esteve, S.A. | Compositions de vaccin basées sur des immunogènes gp41 modifiés |
| DK3299030T3 (da) | 2011-07-11 | 2022-09-05 | Takeda Vaccines Inc | Parenterale norovirus-vaccineformuleringer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| CA1319101C (fr) * | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Proteine de capside nucleique de rotavirus avec ou sans peptides liants comme porteurs de macromolecules immunologiques |
| IE920366A1 (en) * | 1991-02-04 | 1992-08-12 | Univ Saskatchewan | Vp6 encapsulated drug delivery |
| DE69229703T2 (de) * | 1991-05-08 | 2000-04-27 | Schweiz Serum & Impfinst | Wiederhergestellte Influenza-Virosomen mit immunostimulierenden und immunoverstärkenden Eigenschaften und diese enthaltende Impfstoffe |
| DE122007000084I1 (de) * | 1991-07-19 | 2008-03-27 | Univ Queensland St Lucia | Impfstoff gegen Humanes Papillomavirus (Typ 18) |
| EP0835663B1 (fr) * | 1992-05-23 | 2009-09-30 | GlaxoSmithKline Biologicals S.A. | Vaccins combinés contenant des antigènes de surface du virus de l'Hépatite B et d'autres antigènes |
| US5618536A (en) * | 1992-09-03 | 1997-04-08 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric papillomavirus-like particles |
| GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
-
1998
- 1998-04-22 CA CA002288129A patent/CA2288129A1/fr not_active Abandoned
- 1998-04-22 JP JP54812898A patent/JP2002508748A/ja active Pending
- 1998-04-22 EP EP98919845A patent/EP0980257A1/fr not_active Withdrawn
- 1998-04-22 WO PCT/US1998/008146 patent/WO1998050071A1/fr not_active Ceased
- 1998-04-22 AU AU72545/98A patent/AU750702B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998050071A1 (fr) | 1998-11-12 |
| EP0980257A1 (fr) | 2000-02-23 |
| AU7254598A (en) | 1998-11-27 |
| AU750702B2 (en) | 2002-07-25 |
| JP2002508748A (ja) | 2002-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |