CA2019426A1 - Sels de lithium comme reactifs pour la lyse des globules rouges et la denaturation de l'hemoglobine - Google Patents
Sels de lithium comme reactifs pour la lyse des globules rouges et la denaturation de l'hemoglobineInfo
- Publication number
- CA2019426A1 CA2019426A1 CA2019426A CA2019426A CA2019426A1 CA 2019426 A1 CA2019426 A1 CA 2019426A1 CA 2019426 A CA2019426 A CA 2019426A CA 2019426 A CA2019426 A CA 2019426A CA 2019426 A1 CA2019426 A1 CA 2019426A1
- Authority
- CA
- Canada
- Prior art keywords
- hemoglobin
- blood cells
- red blood
- lithium salts
- denaturing reagents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000001554 Hemoglobins Human genes 0.000 title abstract 6
- 108010054147 Hemoglobins Proteins 0.000 title abstract 6
- 210000003743 erythrocyte Anatomy 0.000 title abstract 3
- 229910003002 lithium salt Inorganic materials 0.000 title abstract 3
- 159000000002 lithium salts Chemical class 0.000 title abstract 3
- 230000002934 lysing effect Effects 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000003018 immunoassay Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 238000004925 denaturation Methods 0.000 abstract 1
- 230000036425 denaturation Effects 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- -1 lithium thiocyanate Chemical class 0.000 abstract 1
- ZJZXSOKJEJFHCP-UHFFFAOYSA-M lithium;thiocyanate Chemical compound [Li+].[S-]C#N ZJZXSOKJEJFHCP-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5002—Partitioning blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37958289A | 1989-07-13 | 1989-07-13 | |
| US379,582 | 1989-07-13 | ||
| US522,835 | 1990-05-14 | ||
| US07/522,835 US5151369A (en) | 1989-07-13 | 1990-05-14 | Lithium salts as red blood cell lysing and hemoglobin denaturing reagents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2019426A1 true CA2019426A1 (fr) | 1991-01-13 |
| CA2019426C CA2019426C (fr) | 2000-12-19 |
Family
ID=27008679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002019426A Expired - Lifetime CA2019426C (fr) | 1989-07-13 | 1990-06-20 | Sels de lithium comme reactifs pour la lyse des globules rouges et la denaturation de l'hemoglobine |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US5151369A (fr) |
| CA (1) | CA2019426C (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627738B2 (en) * | 1995-09-15 | 2003-09-30 | Duke University | No-modified hemoglobins and uses therefor |
| US6911427B1 (en) | 1995-09-15 | 2005-06-28 | Duke University | No-modified hemoglobins and uses therefore |
| US5891735A (en) * | 1995-09-15 | 1999-04-06 | Duke University Medical Center | Method for measuring nitric oxide in nitrosyl (FeII)-hemoglobin and S-nitrosohemoglobin |
| US6949384B2 (en) * | 2001-12-21 | 2005-09-27 | Spectromedical Inc. | Method for monitoring degradation of Hb-based blood substitutes |
| US7449339B2 (en) * | 1999-11-23 | 2008-11-11 | Nir Diagnostics Inc. | Spectroscopic method and apparatus for total hemoglobin measurement |
| US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
| US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
| US7094354B2 (en) | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
| US7347617B2 (en) | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
| US8921052B2 (en) * | 2005-04-14 | 2014-12-30 | Panasonic Healthcare Co., Ltd. | Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method |
| CN114994337B (zh) * | 2022-06-07 | 2023-09-05 | 北京市计量检测科学研究院 | 一种血红蛋白的检测方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4255385A (en) * | 1979-10-23 | 1981-03-10 | Abbott Laboratories | Reagent and test kit for determining glycosylated hemoglobin |
| US4801299A (en) * | 1983-06-10 | 1989-01-31 | University Patents, Inc. | Body implants of extracellular matrix and means and methods of making and using such implants |
| US4582789A (en) * | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
| US4880749A (en) * | 1984-06-05 | 1989-11-14 | Eastman Kodak Company | Analytical element and its use in a whole blood hemoglobin assay |
| US4853338A (en) * | 1987-05-20 | 1989-08-01 | Technicon Instruments Corporation | Cyanide-free hemoglobin reagent |
| US4970171A (en) * | 1987-11-09 | 1990-11-13 | Miles Inc. | Denaturant reagents for convenient determination of hemoglobin derivatives in blood |
| US4847209A (en) * | 1987-11-09 | 1989-07-11 | Miles Inc. | Latex agglutination immunoassay in the presence of hemoglobin |
| IL94724A (en) * | 1989-07-13 | 1994-02-27 | Miles Inc | Decomposition of red blood cells and denaturation of hemoglobin by the use of lithium salts |
-
1990
- 1990-05-14 US US07/522,835 patent/US5151369A/en not_active Expired - Lifetime
- 1990-06-20 CA CA002019426A patent/CA2019426C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5151369A (en) | 1992-09-29 |
| CA2019426C (fr) | 2000-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry | ||
| MKEX | Expiry |
Effective date: 20100620 |