BRPI0817275A2 - Combinação farmacêutica de alisquireno e valsartana - Google Patents
Combinação farmacêutica de alisquireno e valsartanaInfo
- Publication number
- BRPI0817275A2 BRPI0817275A2 BRPI0817275-7A BRPI0817275A BRPI0817275A2 BR PI0817275 A2 BRPI0817275 A2 BR PI0817275A2 BR PI0817275 A BRPI0817275 A BR PI0817275A BR PI0817275 A2 BRPI0817275 A2 BR PI0817275A2
- Authority
- BR
- Brazil
- Prior art keywords
- aliskiren
- valsartan
- minutes
- dose combination
- fixed dose
- Prior art date
Links
- UXOWGYHJODZGMF-QORCZRPOSA-N Aliskiren Chemical compound COCCCOC1=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=CC=C1OC UXOWGYHJODZGMF-QORCZRPOSA-N 0.000 title abstract 3
- 239000004072 C09CA03 - Valsartan Substances 0.000 title abstract 3
- 229960004601 aliskiren Drugs 0.000 title abstract 3
- SJSNUMAYCRRIOM-QFIPXVFZSA-N valsartan Chemical compound C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=N[N]1 SJSNUMAYCRRIOM-QFIPXVFZSA-N 0.000 title abstract 3
- 229960004699 valsartan Drugs 0.000 title abstract 3
- 229940000425 combination drug Drugs 0.000 abstract 3
- 238000004090 dissolution Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97590507P | 2007-09-28 | 2007-09-28 | |
| PCT/US2008/077417 WO2009045796A1 (en) | 2007-09-28 | 2008-09-24 | Pharmaceutical combination of aliskiren and valsartan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0817275A2 true BRPI0817275A2 (pt) | 2015-06-16 |
Family
ID=40394241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0817275-7A BRPI0817275A2 (pt) | 2007-09-28 | 2008-09-24 | Combinação farmacêutica de alisquireno e valsartana |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100247645A1 (pt) |
| EP (1) | EP2205279B1 (pt) |
| JP (1) | JP2010540548A (pt) |
| KR (1) | KR20100059912A (pt) |
| CN (1) | CN101808665A (pt) |
| AT (1) | ATE505203T1 (pt) |
| AU (1) | AU2008309059A1 (pt) |
| BR (1) | BRPI0817275A2 (pt) |
| CA (1) | CA2697437A1 (pt) |
| DE (1) | DE602008006243D1 (pt) |
| ES (1) | ES2364538T3 (pt) |
| MX (1) | MX2010003439A (pt) |
| PL (1) | PL2205279T3 (pt) |
| PT (1) | PT2205279E (pt) |
| RU (1) | RU2010116526A (pt) |
| WO (1) | WO2009045796A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110287100A1 (en) * | 2009-01-28 | 2011-11-24 | Sabine Desset-Brethes | Galenic Formulations of Organic Compounds |
| JP2012520895A (ja) * | 2009-03-20 | 2012-09-10 | ノバルティス アーゲー | バルサルタンおよびアリスキレンの一定用量の組合せのガレヌス製剤 |
| AR080683A1 (es) * | 2010-03-16 | 2012-05-02 | Novartis Ag | Composiciones farmaceuticas de aliskiren y metodos de administracion |
| SG174658A1 (en) * | 2010-04-01 | 2011-10-28 | Theravida Inc | Pharmaceutical formulations for the treatment of overactive bladder |
| MX348723B (es) | 2011-05-10 | 2017-06-27 | Theravida Inc | Combinaciones de solifenacina y estimulantes salivales para el tratamiento de la vejiga hiperactiva. |
| CN102247344A (zh) * | 2011-05-30 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种新型降血压组合物 |
| CN102626395B (zh) * | 2012-04-19 | 2014-02-26 | 海南美兰史克制药有限公司 | 一种阿利克仑缬沙坦药物组合物脂质体固体制剂 |
| US10376470B2 (en) * | 2012-05-01 | 2019-08-13 | Althera Life Sciences, Llc | Oral tablet formulation consisting of fixed combination of rosuvastatin and ezetimibe for treatment of hyperlipidemia and cardiovascular diseases |
| WO2013166114A1 (en) * | 2012-05-01 | 2013-11-07 | Althera Life Sciences, Llc | Oral tablet formulation consisting of fixed combination of atorvastatin and ezetimibe |
| WO2013166117A1 (en) * | 2012-05-01 | 2013-11-07 | Althera Life Sciences, Llc | Oral tablet formulation consisting of fixed combination of rosuvastatin and ezetimibe for treatment of hyperlipidemia and cardiovascular diseases |
| MX394356B (es) | 2016-01-20 | 2025-03-24 | Theravida Inc | Métodos y composiciones para tratar hiperhidrosis. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| PE20142101A1 (es) * | 2004-03-17 | 2014-12-27 | Novartis Ag | Composiciones farmaceuticas de aliskiren |
| BRPI0516128A (pt) * | 2004-10-08 | 2008-08-26 | Novartis Ag | uso de inibidores de renina para a prevenção ou tratamento de disfunção diastólica ou insuficiência cardìca diastólica |
| BRPI0609702A2 (pt) * | 2005-03-22 | 2010-04-20 | Novartis Ag | biomarcadores para a eficácia de aliskiren como um agente hipertensivo |
| CN101247832B (zh) * | 2005-06-27 | 2011-12-28 | 第一三共株式会社 | 含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的药物制剂 |
-
2008
- 2008-09-24 PT PT08835893T patent/PT2205279E/pt unknown
- 2008-09-24 KR KR1020107006602A patent/KR20100059912A/ko not_active Withdrawn
- 2008-09-24 DE DE602008006243T patent/DE602008006243D1/de active Active
- 2008-09-24 US US12/679,052 patent/US20100247645A1/en not_active Abandoned
- 2008-09-24 ES ES08835893T patent/ES2364538T3/es active Active
- 2008-09-24 JP JP2010527092A patent/JP2010540548A/ja active Pending
- 2008-09-24 AT AT08835893T patent/ATE505203T1/de active
- 2008-09-24 WO PCT/US2008/077417 patent/WO2009045796A1/en not_active Ceased
- 2008-09-24 CN CN200880108475A patent/CN101808665A/zh active Pending
- 2008-09-24 EP EP08835893A patent/EP2205279B1/en not_active Not-in-force
- 2008-09-24 RU RU2010116526/15A patent/RU2010116526A/ru not_active Application Discontinuation
- 2008-09-24 PL PL08835893T patent/PL2205279T3/pl unknown
- 2008-09-24 BR BRPI0817275-7A patent/BRPI0817275A2/pt not_active IP Right Cessation
- 2008-09-24 MX MX2010003439A patent/MX2010003439A/es active IP Right Grant
- 2008-09-24 AU AU2008309059A patent/AU2008309059A1/en not_active Abandoned
- 2008-09-24 CA CA2697437A patent/CA2697437A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE505203T1 (de) | 2011-04-15 |
| WO2009045796A1 (en) | 2009-04-09 |
| US20100247645A1 (en) | 2010-09-30 |
| KR20100059912A (ko) | 2010-06-04 |
| PL2205279T3 (pl) | 2011-09-30 |
| JP2010540548A (ja) | 2010-12-24 |
| RU2010116526A (ru) | 2011-11-10 |
| CN101808665A (zh) | 2010-08-18 |
| ES2364538T3 (es) | 2011-09-06 |
| PT2205279E (pt) | 2011-07-11 |
| EP2205279B1 (en) | 2011-04-13 |
| CA2697437A1 (en) | 2009-04-09 |
| AU2008309059A1 (en) | 2009-04-09 |
| MX2010003439A (es) | 2010-04-21 |
| DE602008006243D1 (de) | 2011-05-26 |
| EP2205279A1 (en) | 2010-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |