BR9812644B1 - quinolonas antimicrobianas, composição farmacêutica e uso das mesmas. - Google Patents
quinolonas antimicrobianas, composição farmacêutica e uso das mesmas.Info
- Publication number
- BR9812644B1 BR9812644B1 BRPI9812644-0A BR9812644A BR9812644B1 BR 9812644 B1 BR9812644 B1 BR 9812644B1 BR 9812644 A BR9812644 A BR 9812644A BR 9812644 B1 BR9812644 B1 BR 9812644B1
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- antimicrobial quinolones
- quinolones
- antimicrobial
- pharmaceutical
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000007660 quinolones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5889197P | 1997-09-15 | 1997-09-15 | |
| US13985998A | 1998-08-25 | 1998-08-25 | |
| PCT/US1998/019138 WO1999014214A1 (en) | 1997-09-15 | 1998-09-15 | Antimicrobial quinolones, their compositions and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR9812644A BR9812644A (pt) | 2001-12-18 |
| BR9812644B1 true BR9812644B1 (pt) | 2010-07-13 |
Family
ID=26738133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9812644-0A BR9812644B1 (pt) | 1997-09-15 | 1998-09-15 | quinolonas antimicrobianas, composição farmacêutica e uso das mesmas. |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US6329391B1 (pt) |
| EP (1) | EP1015445B1 (pt) |
| JP (1) | JP4669607B2 (pt) |
| KR (1) | KR100423778B1 (pt) |
| CN (1) | CN1264837C (pt) |
| AR (1) | AR013493A1 (pt) |
| AT (1) | ATE423776T1 (pt) |
| AU (1) | AU735186B2 (pt) |
| BR (1) | BR9812644B1 (pt) |
| CA (1) | CA2303389C (pt) |
| CO (1) | CO4970702A1 (pt) |
| CY (1) | CY1110255T1 (pt) |
| CZ (1) | CZ299554B6 (pt) |
| DE (1) | DE69840599D1 (pt) |
| DK (1) | DK1015445T3 (pt) |
| ES (1) | ES2321042T3 (pt) |
| HU (1) | HUP0100051A3 (pt) |
| ID (1) | ID24703A (pt) |
| IL (2) | IL135036A0 (pt) |
| MY (1) | MY138335A (pt) |
| NO (1) | NO323563B1 (pt) |
| NZ (1) | NZ503740A (pt) |
| PE (1) | PE128799A1 (pt) |
| PL (1) | PL339408A1 (pt) |
| PT (1) | PT1015445E (pt) |
| RU (1) | RU2193558C2 (pt) |
| SA (1) | SA99191136B1 (pt) |
| SK (1) | SK286420B6 (pt) |
| TR (2) | TR200001435T2 (pt) |
| WO (1) | WO1999014214A1 (pt) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
| SK286420B6 (sk) | 1997-09-15 | 2008-09-05 | The Procter & Gamble Company | Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie |
| AU757805B2 (en) * | 1998-11-24 | 2003-03-06 | Daiichi Pharmaceutical Co., Ltd. | Cycloalkyl-substituted aminomethylpyrrolidine derivatives |
| US6750224B1 (en) | 1999-05-07 | 2004-06-15 | Wockhardt Limited | Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment |
| EP1175217B8 (en) * | 1999-05-07 | 2009-03-18 | Wockhardt Limited | (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents |
| US6514986B2 (en) | 2000-11-22 | 2003-02-04 | Wockhardt Limited | Chiral fluoroquinolone arginine salt forms |
| US6608078B2 (en) | 2000-05-08 | 2003-08-19 | Wockhardt Limited | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
| US7098219B2 (en) | 2000-08-01 | 2006-08-29 | Wockhart Limited | Inhibitors of cellular efflux pumps of microbes |
| PT1336611E (pt) * | 2000-11-20 | 2007-12-06 | Daiichi Sankyo Co Ltd | Compostos desalogenados |
| RU2298006C2 (ru) * | 2000-11-20 | 2007-04-27 | Дайити Фармасьютикал Ко., Лтд. | Дегалогенированные соединения, антибактериальное средство и терапевтическое средство на их основе, способ получения антибактериального или лекарственного средства, применение дегалогенированных соединений для получения антибактериального или лекарственного средства |
| AU3089102A (en) * | 2000-12-14 | 2002-06-24 | Procter & Gamble | Antimicrobial quinolones |
| DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
| US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| US6878713B2 (en) | 2001-04-25 | 2005-04-12 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| WO2003099815A1 (en) | 2002-05-28 | 2003-12-04 | Wockhardt Limited | Crystalline fluoroquinolone arginine salt form |
| US6900224B2 (en) * | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| KR100678800B1 (ko) | 2002-11-21 | 2007-02-05 | 화이자 프로덕츠 인코포레이티드 | 3-아미노-피페리딘 유도체 및 그의 제조 방법 |
| EP1567117B1 (en) * | 2002-11-26 | 2012-02-08 | The University of Chicago | Prevention and treatment of microbe-mediated epithelial disorders |
| RU2260002C2 (ru) * | 2003-08-08 | 2005-09-10 | ООО "Исследовательский институт химического разнообразия" | Замещенные 6-сульфо-2-оксо-1,2-дигидрохинолин 4-карбоновые кислоты и их производные (варианты) и фокусированная библиотека |
| JP4675234B2 (ja) * | 2003-06-06 | 2011-04-20 | 第一三共株式会社 | 光学活性なキノロンカルボン酸誘導体の製造中間体およびその製造法 |
| DK1660495T3 (da) * | 2003-09-04 | 2007-11-05 | Wockhardt Ltd | Benzoquinolizin-2-carboxylsyreargininsalt,tetrahydrat |
| DE10341534A1 (de) * | 2003-09-09 | 2005-03-31 | Bayer Chemicals Ag | Difluoralkylaromaten |
| WO2005026147A1 (ja) | 2003-09-10 | 2005-03-24 | Kyorin Pharmaceutical Co., Ltd. | 7−(4−置換−3−シクロプロピルアミノメチル−1−ピロリジニル)キノロンカルボン酸誘導体 |
| SI1675852T1 (sl) * | 2003-09-22 | 2009-06-30 | Janssen Pharmaceutica Nv | 7-amino alkilidenil-heterociklični kinoloni in naftiridoni |
| SE0400235D0 (sv) * | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| MX2007000336A (es) * | 2004-07-02 | 2007-03-28 | Daiichi Seiyaku Co | Composicion medicinal que contiene quinolona. |
| US7732612B2 (en) * | 2004-09-09 | 2010-06-08 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| DE102006005861A1 (de) * | 2006-02-09 | 2007-08-23 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone III |
| DE102006010643A1 (de) * | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
| TWI391378B (zh) * | 2006-03-16 | 2013-04-01 | Astellas Pharma Inc | 喹啉酮衍生物或其製藥學上可被容許之鹽 |
| EP1999125A2 (en) * | 2006-03-28 | 2008-12-10 | The Procter and Gamble Company | A coupling process for preparing quinolone intermediates |
| KR101030202B1 (ko) * | 2006-03-28 | 2011-04-22 | 워너 칠콧 컴퍼니 엘엘씨 | 퀴놀론 중간체의 제조를 위한 수소화물 환원 방법 |
| CN101045725B (zh) * | 2006-03-28 | 2012-12-05 | 太景生物科技股份有限公司 | 某些喹诺酮化合物的苹果酸盐和多晶型物 |
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| US8222407B2 (en) * | 2007-05-24 | 2012-07-17 | Kyorin Pharmaceutical Co., Ltd. | Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| US7902227B2 (en) | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
| US8658183B2 (en) * | 2007-08-09 | 2014-02-25 | Taigen Biotechnology Company, Ltd. | Antimicrobial parenteral formulation |
| CN101361739B (zh) * | 2007-08-09 | 2012-03-14 | 太景生物科技股份有限公司 | 抗菌剂的肠胃外制剂 |
| KR20110044168A (ko) * | 2008-07-01 | 2011-04-28 | 타이젠 바이오테크놀러지 컴퍼니 리미티드 | 항생제 내성 세균 감염의 치료 |
| CN101618039B (zh) * | 2008-07-02 | 2012-04-11 | 太景生物科技股份有限公司 | 肺炎的治疗药物 |
| US20120157492A1 (en) * | 2008-07-15 | 2012-06-21 | Taigen Biotechnology Co., Ltd. | Antibiotic drug |
| FR2936798B1 (fr) * | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2937034B1 (fr) * | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
| FR2936951B1 (fr) * | 2008-10-10 | 2010-12-03 | Novexel | Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments |
| TWI386395B (zh) * | 2008-12-15 | 2013-02-21 | Taigen Biotechnology Co Ltd | 哌啶衍生物的立體有擇合成 |
| JP5789611B2 (ja) * | 2009-10-23 | 2015-10-07 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターを調製するためのプロセス |
| WO2011143145A1 (en) * | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-alkyl and n-acyl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| CN102746223B (zh) * | 2012-07-30 | 2013-10-23 | 浙江新东港药业股份有限公司 | 一种氟哌酸与氯哌酸的分离方法 |
| CN103819401B (zh) * | 2012-11-19 | 2016-04-13 | 浙江中欣氟材股份有限公司 | 1-环丙基-4-氧代-7-氟-8-甲氧基-1,4-二氢喹啉-3-羧酸的合成方法 |
| EP3088399A4 (en) | 2013-12-26 | 2017-10-25 | Kinki University | Alkoxycarbonyl hemiacetal-type ester prodrug of pyridone carboxylic acid antibacterial drug |
| RU2636751C1 (ru) | 2016-11-02 | 2017-12-01 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Антибактериальные средства на основе производных ципрофлоксацина |
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| JP2023517539A (ja) * | 2020-03-03 | 2023-04-26 | レドナ・セラピューティクス,インコーポレーテッド | Rna結合タンパク質またはrna修飾タンパク質を標的とする化合物 |
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-
1998
- 1998-09-15 SK SK381-2000A patent/SK286420B6/sk not_active IP Right Cessation
- 1998-09-15 CZ CZ20000931A patent/CZ299554B6/cs not_active IP Right Cessation
- 1998-09-15 PE PE1998000877A patent/PE128799A1/es not_active IP Right Cessation
- 1998-09-15 IL IL13503698A patent/IL135036A0/xx active IP Right Grant
- 1998-09-15 HU HU0100051A patent/HUP0100051A3/hu unknown
- 1998-09-15 WO PCT/US1998/019138 patent/WO1999014214A1/en not_active Ceased
- 1998-09-15 PT PT98948208T patent/PT1015445E/pt unknown
- 1998-09-15 ES ES98948208T patent/ES2321042T3/es not_active Expired - Lifetime
- 1998-09-15 PL PL98339408A patent/PL339408A1/xx not_active Application Discontinuation
- 1998-09-15 AR ARP980104582A patent/AR013493A1/es active IP Right Grant
- 1998-09-15 DK DK98948208T patent/DK1015445T3/da active
- 1998-09-15 AT AT98948208T patent/ATE423776T1/de active
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- 1998-09-15 BR BRPI9812644-0A patent/BR9812644B1/pt not_active IP Right Cessation
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- 1998-09-15 EP EP98948208A patent/EP1015445B1/en not_active Expired - Lifetime
- 1998-09-15 KR KR10-2000-7002736A patent/KR100423778B1/ko not_active Expired - Lifetime
- 1998-09-15 JP JP2000511763A patent/JP4669607B2/ja not_active Expired - Lifetime
- 1998-09-15 DE DE69840599T patent/DE69840599D1/de not_active Expired - Lifetime
- 1998-09-15 TR TR2005/05120T patent/TR200505120T2/xx unknown
- 1998-09-15 AU AU94829/98A patent/AU735186B2/en not_active Expired
- 1998-09-15 CN CNB98810945XA patent/CN1264837C/zh not_active Expired - Lifetime
- 1998-09-15 ID IDW20000686A patent/ID24703A/id unknown
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- 1998-09-15 RU RU2000109589/04A patent/RU2193558C2/ru active
- 1998-09-15 CO CO98053005A patent/CO4970702A1/es unknown
- 1998-09-15 CA CA002303389A patent/CA2303389C/en not_active Expired - Lifetime
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1999
- 1999-02-28 SA SA99191136A patent/SA99191136B1/ar unknown
- 1999-03-10 US US09/266,197 patent/US6329391B1/en not_active Expired - Lifetime
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