BR9711318A - Processo para preparar intermedi rios para florfenicol - Google Patents

Processo para preparar intermedi rios para florfenicol

Info

Publication number: BR9711318A
Authority: BR; Brazil
Prior art keywords: florfenicol; preparing intermediates; intermediates; preparing
Prior art date: 1996-08-19

Application number

BR9711318A

Other languages

English (en)

Other versions

BR9711318B1 (pt

Inventor

James C Towson

Dhiru B Vashi

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-18

Publication date

1999-08-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9711318(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-08-18 Application filed by Schering Corp filed Critical Schering Corp

1999-08-17 Publication of BR9711318A publication Critical patent/BR9711318A/pt

2009-01-13 Publication of BR9711318B1 publication Critical patent/BR9711318B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BRPI9711318-2A 1996-08-19 1997-08-18 processo para preparar intermediÁrios para florfenicol. BR9711318B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/699,271 US5663361A (en)	1996-08-19	1996-08-19	Process for preparing intermediates to florfenicol
PCT/US1997/014205 WO1998007709A1 (en)	1996-08-19	1997-08-18	Process for preparing intermediates to florfenicol

Publications (2)

Publication Number	Publication Date
BR9711318A true BR9711318A (pt)	1999-08-17
BR9711318B1 BR9711318B1 (pt)	2009-01-13

Family

ID=24808601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9711318-2A BR9711318B1 (pt)	1996-08-19	1997-08-18	processo para preparar intermediÁrios para florfenicol.

Country Status (30)

Country	Link
US (1)	US5663361A (pt)
EP (1)	EP0922040B2 (pt)
JP (1)	JP3274868B2 (pt)
KR (1)	KR100286851B1 (pt)
CN (1)	CN1097583C (pt)
AR (1)	AR008298A1 (pt)
AT (1)	ATE283847T1 (pt)
AU (1)	AU714495B2 (pt)
BR (1)	BR9711318B1 (pt)
CA (1)	CA2264116C (pt)
CO (1)	CO4560550A1 (pt)
CZ (1)	CZ297915B6 (pt)
DE (1)	DE69731835T3 (pt)
DK (1)	DK0922040T3 (pt)
ES (1)	ES2234026T5 (pt)
HU (1)	HU229610B1 (pt)
ID (1)	ID18047A (pt)
IL (1)	IL128574A (pt)
MY (1)	MY115679A (pt)
NO (1)	NO312962B1 (pt)
NZ (1)	NZ334111A (pt)
PE (1)	PE99798A1 (pt)
PL (2)	PL196454B1 (pt)
PT (1)	PT922040E (pt)
SI (1)	SI0922040T1 (pt)
SK (1)	SK286124B6 (pt)
TR (2)	TR200800474T2 (pt)
TW (1)	TW381075B (pt)
WO (1)	WO1998007709A1 (pt)
ZA (1)	ZA977406B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1173933C (zh) *	2001-06-01	2004-11-03	中国科学院上海有机化学研究所	一种从l型取代苯丝氨酸酯制备d－（－）－苏式1－r－取代苯基－2－二氯乙酰氨基－3－氟－1－丙醇的方法
CN1649829A (zh) *	2002-03-08	2005-08-03	先灵-普劳有限公司	新型氟苯尼考类抗生素
MY146351A (en)	2003-05-29	2012-08-15	Schering Plough Ltd	Compositions for treating infection in cattle and swine
US7439268B2 (en) *	2003-07-18	2008-10-21	Idexx Laboratories	Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) *	2003-08-27	2005-03-03	Idexx Laboratories, Inc.	Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) *	2003-10-06	2006-10-24	Aurobindo Pharma Limited	Process for preparing florfenicol
PE20060489A1 (es)	2004-08-13	2006-06-19	Schering Plough Ltd	Formulacion farmaceutica que comprende un antibiotico, un triazol y un corticosteroide
ATE406348T1 (de)	2004-09-23	2008-09-15	Schering Plough Ltd	Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
MX2007006072A (es) *	2004-11-19	2007-07-11	Schering Plough Ltd	Control de parasitos en animales mediante el uso de derivados del parasiticida 2-fenil-3-(1h-pirrol-2-il)acrilonitrilo.
ES2315942T3 (es) *	2004-12-21	2009-04-01	Intervet International Bv	Composicion veterinaria inyectable que contiene florfenicol.
MX2007015729A (es) *	2005-06-09	2008-02-21	Schering Plough Ltd	Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
AU2006287696A1 (en)	2005-09-07	2007-03-15	Schering-Plough Pty. Limited	A process for preparing oxazolidine protected aminodiol compounds useful as intermediates to Florfenicol
US8119667B2 (en) *	2005-12-29	2012-02-21	Schering-Plough Animal Health Corporation	Carbonates of fenicol antibiotics
US7518017B2 (en)	2006-02-17	2009-04-14	Idexx Laboratories	Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) *	2006-04-10	2007-10-11	Winzenberg Kevin N	N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
CN101600686A (zh) *	2006-12-13	2009-12-09	先灵-普劳有限公司	氯霉素、甲砜霉素及其类似物的水溶性前药
EP2091909A1 (en) *	2006-12-13	2009-08-26	Schering-Plough Ltd.	Water-soluble prodrugs of florfenicol and its analogs
KR20100028537A (ko) *	2007-04-27	2010-03-12	쉐링-프라우 리미티드	사이클로덱스트린을 사용하여 플로르페니콜 및 구조적으로 관련된 항생제의 용해도를 증진시키기 위한 화합물 및 방법
CA2688432A1 (en) *	2007-05-30	2008-12-11	Schering-Plough Ltd.	A process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
DK2957284T3 (en)	2007-06-27	2018-02-05	Du Pont	PROCEDURE TO CHECK ANIMALS FOR ANIMALS
WO2009015111A2 (en) *	2007-07-25	2009-01-29	Intervet Intermatonal B.V.	Process for preparing oxazolidine-and oxazolidinone-aminodiols and related intermediates
US7550625B2 (en) *	2007-10-19	2009-06-23	Idexx Laboratories	Esters of florfenicol
MX2010005087A (es) *	2007-11-09	2010-05-21	Intervet Int Bv	Formulacion solida de liberacion rapida, preparacion y uso de la misma.
TWI401023B (zh)	2008-02-06	2013-07-11	Du Pont	中離子農藥
JP2011529895A (ja) *	2008-07-30	2011-12-15	インターベツト・インターナシヨナル・ベー・ベー	フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
MX2012001651A (es)	2009-08-05	2012-03-16	Du Pont	Pesticidas mesoionicos.
UA107804C2 (en)	2009-08-05	2015-02-25	Du Pont	Mixtures of pesticides mezoionnyh
UA110924C2 (uk)	2009-08-05	2016-03-10	Е. І. Дю Пон Де Немур Енд Компані	Мезоіонні пестициди
US20120122680A1 (en)	2009-08-05	2012-05-17	E.I. Du Pont De Nemours And Company	Mesoionic pesticides
BRPI1002023A2 (pt)	2010-03-01	2011-10-25	Nanocore Biotecnologia S A	forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
MX2012013758A (es)	2010-05-27	2013-01-24	Du Pont	Forma cristalina de 4-[5-[3-cloro-5-trifluorometil)fenil]-4,5-dihi dro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoro etil)amino]etil]-1-naftalenocarboxamida.
WO2012087630A1 (en)	2010-12-20	2012-06-28	E.I. Du Pont De Nemours And Company	Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en)	2012-04-17	2013-10-24	E. I. Du Pont De Nemours And Company	Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) *	2012-10-31	2014-07-02	绍兴民生医药有限公司	(4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) *	2013-04-19	2016-04-06	浙江科技学院	一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) *	2016-07-31	2018-01-16	浙江润康药业有限公司	氟苯尼考的制备方法
CN106631872A (zh) *	2016-12-13	2017-05-10	浙江普洛家园药业有限公司	一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) *	2019-05-08	2022-05-03	江南大学	一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) *	2023-12-28	2024-03-22	山东国邦药业有限公司	一种氟苯尼考中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2759001A (en)	1952-03-01	1956-08-14	Parke Davis & Co	Process for the production of delta2-oxazolines
US4361557A (en) *	1980-01-28	1982-11-30	Schering Corporation	1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
EP0130633B1 (en) *	1983-06-02	1996-10-09	ZAMBON GROUP S.p.A.	Process for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoro propane derivatives
US4876352A (en) *	1988-09-14	1989-10-24	Schering Corporation	Pressurized fluorination of hydroxy alkyl groups
KR920701469A (ko) †	1989-05-15	1992-08-11	스테이너 브이. 캔스태드	향균성 화합물 및 이의 중간물질의 제조방법
NZ250394A (en) *	1990-10-25	1994-10-26	Schering Corp	Fluorinated and hydroxylated oxazoline compounds

1996
- 1996-08-19 US US08/699,271 patent/US5663361A/en not_active Expired - Lifetime
1997
- 1997-08-15 CO CO97047276A patent/CO4560550A1/es unknown
- 1997-08-15 AR ARP970103736A patent/AR008298A1/es not_active Application Discontinuation
- 1997-08-18 SK SK199-99A patent/SK286124B6/sk not_active IP Right Cessation
- 1997-08-18 ID IDP972887A patent/ID18047A/id unknown
- 1997-08-18 BR BRPI9711318-2A patent/BR9711318B1/pt not_active IP Right Cessation
- 1997-08-18 WO PCT/US1997/014205 patent/WO1998007709A1/en not_active Ceased
- 1997-08-18 PT PT97938263T patent/PT922040E/pt unknown
- 1997-08-18 NZ NZ334111A patent/NZ334111A/en not_active IP Right Cessation
- 1997-08-18 ZA ZA9707406A patent/ZA977406B/xx unknown
- 1997-08-18 AU AU40638/97A patent/AU714495B2/en not_active Expired
- 1997-08-18 MY MYPI97003778A patent/MY115679A/en unknown
- 1997-08-18 CN CN97198768A patent/CN1097583C/zh not_active Expired - Lifetime
- 1997-08-18 TR TR2008/00474T patent/TR200800474T2/xx unknown
- 1997-08-18 CZ CZ0054099A patent/CZ297915B6/cs not_active IP Right Cessation
- 1997-08-18 CA CA002264116A patent/CA2264116C/en not_active Expired - Lifetime
- 1997-08-18 DE DE69731835T patent/DE69731835T3/de not_active Expired - Lifetime
- 1997-08-18 AT AT97938263T patent/ATE283847T1/de active
- 1997-08-18 PL PL331644A patent/PL196454B1/pl not_active IP Right Cessation
- 1997-08-18 PE PE1997000728A patent/PE99798A1/es not_active Application Discontinuation
- 1997-08-18 TR TR1999/00354T patent/TR199900354T2/xx unknown
- 1997-08-18 HU HU9904166A patent/HU229610B1/hu unknown
- 1997-08-18 JP JP51080598A patent/JP3274868B2/ja not_active Expired - Lifetime
- 1997-08-18 SI SI9730688T patent/SI0922040T1/xx unknown
- 1997-08-18 IL IL12857497A patent/IL128574A/en not_active IP Right Cessation
- 1997-08-18 DK DK97938263T patent/DK0922040T3/da active
- 1997-08-18 ES ES97938263T patent/ES2234026T5/es not_active Expired - Lifetime
- 1997-08-18 PL PL378741A patent/PL198553B1/pl not_active IP Right Cessation
- 1997-08-18 EP EP97938263.7A patent/EP0922040B2/en not_active Expired - Lifetime
- 1997-08-19 TW TW086111823A patent/TW381075B/zh not_active IP Right Cessation
1999
- 1999-02-18 NO NO19990756A patent/NO312962B1/no not_active IP Right Cessation
- 1999-02-18 KR KR1019997001290A patent/KR100286851B1/ko not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN1233244A (zh)	1999-10-27
TR200800474T2 (tr)	2008-04-21
HK1017890A1 (en)	1999-12-03
CZ54099A3 (cs)	1999-07-14
NO990756L (no)	1999-02-18
HUP9904166A3 (en)	2001-11-28
CN1097583C (zh)	2003-01-01
JP3274868B2 (ja)	2002-04-15
IL128574A0 (en)	2000-01-31
SK286124B6 (sk)	2008-04-07
TW381075B (en)	2000-02-01
CA2264116C (en)	2002-07-02
AR008298A1 (es)	1999-12-29
ATE283847T1 (de)	2004-12-15
DE69731835T2 (de)	2005-07-21
CA2264116A1 (en)	1998-02-26
IL128574A (en)	2002-04-21
KR20000068178A (ko)	2000-11-25
HUP9904166A2 (hu)	2000-05-28
JP2000501424A (ja)	2000-02-08
ID18047A (id)	1998-02-19
SK19999A3 (en)	2000-02-14
PT922040E (pt)	2005-02-28
PL196454B1 (pl)	2008-01-31
PE99798A1 (es)	1998-12-28
AU714495B2 (en)	2000-01-06
PL198553B1 (pl)	2008-06-30
EP0922040A1 (en)	1999-06-16
DE69731835D1 (de)	2005-01-05
BR9711318B1 (pt)	2009-01-13
HU229610B1 (en)	2014-03-28
KR100286851B1 (ko)	2001-04-16
US5663361A (en)	1997-09-02
DK0922040T3 (da)	2005-04-04
EP0922040B2 (en)	2013-07-17
WO1998007709A1 (en)	1998-02-26
DE69731835T3 (de)	2013-12-05
MY115679A (en)	2003-08-30
SI0922040T1 (en)	2005-02-28
NZ334111A (en)	1999-10-28
EP0922040B1 (en)	2004-12-01
AU4063897A (en)	1998-03-06
ZA977406B (en)	1998-02-18
NO312962B1 (no)	2002-07-22
NO990756D0 (no)	1999-02-18
PL331644A1 (en)	1999-08-02
CZ297915B6 (cs)	2007-04-25
ES2234026T3 (es)	2005-06-16
CO4560550A1 (es)	1998-02-10
TR199900354T2 (xx)	1999-05-21
ES2234026T5 (es)	2013-11-12

Publication	Publication Date	Title
BR9711318A (pt)	1999-08-17	Processo para preparar intermedi rios para florfenicol
BR9706413A (pt)	1999-06-15	Processo para controlar nova seleção de canal
BR9609192A (pt)	1999-05-11	Processo para produzir arame
BR9703580A (pt)	1998-11-10	Processo para preparar sildenafil
BR9710457A (pt)	1999-08-17	Processo para a prepara-Æo de ciclohexanodimetanol
FI991477A7 (fi)	1999-06-29	Menetelmä tolterodiinin valmistamiseksi
BR9710099A (pt)	1999-08-10	Processo para produzir compostos
BR9612505A (pt)	1999-07-20	Plocesso para produção de fosgênio
BR9708535A (pt)	1999-08-03	Processo para produzir um composto
BR9705174A (pt)	1999-07-20	Processo para produzir metionina
AR017655A1 (es)	2001-09-12	Metodo para preparar eteres de monofluormetilo
BR9703078A (pt)	1998-11-10	Processo para obtenção de aldeídos
BR9701136A (pt)	1998-09-01	Processo para obtenção de isoforona
BR9710081A (pt)	1999-08-10	Processo para a preparaçÃo de 17-ésteres de 9alpha,21-dihalo-pregnano-1beta, 17alpha-diol-20-onas
BR9711003A (pt)	1999-08-17	Processo para a prepara-Æo de um dicarboxilato oxadiazina
BR9612457A (pt)	1999-07-13	Processo para a fabricação de felodipina
BR9704858A (pt)	1999-08-03	Processo para a fabricação de corpos vazados
PT1039888E (pt)	2003-07-31	Metodo para aumentar a producao e melhorar a qualidade do semen
IT1283447B1 (it)	1998-04-21	Processo di preparazione del valaciclovir e relativi intermedi
PT880498E (pt)	2002-05-31	Processo para a preparacao de compostos dicetonicos
BR9706239A (pt)	1999-06-01	Processo para preparação de 3-(1-hidroxifenil-1-alcoxiimino-metil)dioxazinas
BR9710391A (pt)	1999-08-17	Processo para prepara-Æo de fenetilaminas rac-micas
BR9501925A (pt)	1996-03-05	Azocorantes,sulfopiridonas e processo para obtenção das mesmas
PT1124792E (pt)	2004-12-31	Processo para a preparacao de cetiminas
BR9701685A (pt)	1998-11-10	Composição redutível em água e processo para preparar uma composição redutível em água

Legal Events

Date	Code	Title	Description
2004-03-30	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2005-04-26	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2005-09-20	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2006-04-25	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: INDEFIRO O PEDIDO DE PATENTE COM BASE NOS ARTIGOS 8 E 11 DA LPI NO 9.279 DE 14/05/1996.
2006-08-15	B12B	Appeal against refusal [chapter 12.2 patent gazette]
2009-03-10	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/03/2009, OBSERVADAS AS CONDICOES LEGAIS.
2013-10-01	B25D	Requested change of name of applicant approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2013-10-15	B25G	Requested change of headquarter approved	Owner name: MERCK SHARP AND DOHME CORP. (US)
2019-05-21	B21A	Patent or certificate of addition expired [chapter 21.1 patent gazette]	Free format text: PATENTE EXTINTA EM 10.03.2019