BG25078A3 - Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина - Google Patents

Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина

Info

Publication number: BG25078A3
Authority: BG; Bulgaria
Prior art keywords: dihydropyridine; methoxycarbonyl; nitrophenyl; dimethyl; obtaining
Prior art date: 1975-11-05

Application number

BG035341A

Other languages

Bulgarian (bg)

English (en)

Inventor

Egbert Wehinger

Friedrich Bossert

Arend Heise

Stanislav Karda

Kurt Stoepel

Walle Vater

Original Assignee

Неизвестен

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-11-05

Filing date

1976-11-01

Publication date

1978-07-12

1976-11-01 Application filed by Неизвестен filed Critical Неизвестен

1978-07-12 Publication of BG25078A3 publication Critical patent/BG25078A3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BG035341A 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина BG25078A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2549568A DE2549568C3 (de)	1975-11-05	1975-11-05	2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number	Publication Date
BG25078A3 true BG25078A3 (bg)	1978-07-12

Family

ID=5960951

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
BG035341A BG25078A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035345A BG24805A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG034575A BG24668A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина
BG035344A BG24804A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035342A BG25079A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина
BG035343A BG24803A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина

Family Applications After (5)

Application Number	Title	Priority Date	Filing Date
BG035345A BG24805A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG034575A BG24668A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина
BG035344A BG24804A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035342A BG25079A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина
BG035343A BG24803A3 (bg)	1975-11-05	1976-11-01	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина

Country Status (27)

Country	Link
JP (1)	JPS5259161A (xx)
AT (1)	AT352129B (xx)
AU (1)	AU498964B2 (xx)
BE (1)	BE847968A (xx)
BG (6)	BG25078A3 (xx)
CA (1)	CA1085406A (xx)
CH (2)	CH623038A5 (xx)
CS (1)	CS200499B2 (xx)
DE (1)	DE2549568C3 (xx)
DK (1)	DK146762C (xx)
ES (2)	ES452986A1 (xx)
FI (1)	FI60704C (xx)
FR (1)	FR2330395A1 (xx)
GB (1)	GB1516793A (xx)
GR (1)	GR61241B (xx)
HK (1)	HK12681A (xx)
IE (1)	IE43984B1 (xx)
IL (1)	IL50817A (xx)
LU (2)	LU76133A1 (xx)
NL (2)	NL175915C (xx)
NO (1)	NO145574C (xx)
NZ (1)	NZ182502A (xx)
PL (2)	PL106084B1 (xx)
PT (1)	PT65797B (xx)
RO (1)	RO70295A (xx)
SE (1)	SE423542B (xx)
ZA (1)	ZA766622B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146630A (en) *	1976-11-12	1979-03-27	Boehringer Mannheim Gmbh	Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) *	1978-02-14	1980-01-05	Yamanouchi Pharmaceut Co Ltd	1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) *	1982-04-06	1983-10-13	Bayer Ag, 5090 Leverkusen	Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) *	1982-06-15	1983-12-15	Bayer Ag, 5090 Leverkusen	Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) *	1982-11-27	1984-06-02	エムケ−精工株式会社	扉
DE3312216A1 (de) *	1983-04-05	1984-10-11	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) *	1983-04-05	1984-10-18	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) *	1984-05-23	1988-12-27	Bayer Aktiengesellschaft	Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (de) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/de not_active Expired
1976
- 1976-10-22 NO NO763608A patent/NO145574C/no unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/ja active Granted
- 1976-11-01 BG BG035341A patent/BG25078A3/xx unknown
- 1976-11-01 BG BG035345A patent/BG24805A3/xx unknown
- 1976-11-01 BG BG034575A patent/BG24668A3/xx unknown
- 1976-11-01 BG BG035344A patent/BG24804A3/xx unknown
- 1976-11-01 BG BG035342A patent/BG25079A3/xx unknown
- 1976-11-01 BG BG035343A patent/BG24803A3/xx unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/xx unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 RO RO7688294A patent/RO70295A/ro unknown
- 1976-11-02 CS CS767068A patent/CS200499B2/cs unknown
- 1976-11-02 CH CH1381976A patent/CH623038A5/de not_active IP Right Cessation
- 1976-11-02 IL IL50817A patent/IL50817A/xx unknown
- 1976-11-03 AT AT814276A patent/AT352129B/de not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/pl unknown
- 1976-11-03 PL PL1976201800A patent/PL105940B1/pl unknown
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/xx not_active IP Right Cessation
- 1976-11-03 FI FI763160A patent/FI60704C/fi not_active IP Right Cessation
- 1976-11-04 PT PT65797A patent/PT65797B/pt unknown
- 1976-11-04 SE SE7612308A patent/SE423542B/xx not_active IP Right Cessation
- 1976-11-04 BE BE172063A patent/BE847968A/xx not_active IP Right Cessation
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-04 DK DK498476A patent/DK146762C/da not_active IP Right Cessation
- 1976-11-04 ES ES452986A patent/ES452986A1/es not_active Expired
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 GR GR52093A patent/GR61241B/el unknown
- 1976-11-04 ZA ZA766622A patent/ZA766622B/xx unknown
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
- 1976-11-05 FR FR7633488A patent/FR2330395A1/fr active Granted
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/es not_active Expired
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/de not_active IP Right Cessation
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/xx unknown
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/nl unknown

Also Published As

Publication number	Publication date
SE423542B (sv)	1982-05-10
BE847968A (fr)	1977-05-04
JPS5647185B2 (xx)	1981-11-07
BG24803A3 (bg)	1978-05-12
BG24668A3 (bg)	1978-04-12
GB1516793A (en)	1978-07-05
FR2330395B1 (xx)	1978-12-22
DK498476A (da)	1977-05-06
DE2549568B2 (de)	1980-08-21
DE2549568C3 (de)	1981-10-29
AU1935876A (en)	1978-05-11
IE43984L (en)	1977-05-05
FR2330395A1 (fr)	1977-06-03
FI763160A7 (xx)	1977-05-06
ZA766622B (en)	1977-10-26
PL106084B1 (pl)	1979-11-30
CH623038A5 (en)	1981-05-15
NO145574B (no)	1982-01-11
DK146762C (da)	1984-06-12
ES463166A1 (es)	1978-07-16
LU88275I2 (xx)	1994-02-03
NO145574C (no)	1982-04-21
CA1085406A (en)	1980-09-09
ATA814276A (de)	1979-02-15
FI60704C (fi)	1982-03-10
NZ182502A (en)	1978-07-28
SE7612308L (sv)	1977-05-06
PT65797B (de)	1978-05-12
IE43984B1 (en)	1981-07-15
NL175915C (nl)	1985-01-16
LU76133A1 (xx)	1977-06-02
AU498964B2 (en)	1979-03-29
NL930035I2 (nl)	1993-10-01
JPS5259161A (en)	1977-05-16
DK146762B (da)	1983-12-27
RO70295A (ro)	1981-08-17
IL50817A (en)	1979-07-25
PL105940B1 (pl)	1979-11-30
CS200499B2 (en)	1980-09-15
FI60704B (fi)	1981-11-30
ES452986A1 (es)	1977-12-16
IL50817A0 (en)	1977-01-31
DE2549568A1 (de)	1977-05-18
AT352129B (de)	1979-09-10
BG24804A3 (bg)	1978-05-12
NO763608L (xx)	1977-05-06
NL7612198A (nl)	1977-05-09
PT65797A (de)	1976-12-01
BG25079A3 (bg)	1978-07-12
BG24805A3 (bg)	1978-05-12
HK12681A (en)	1981-04-10
GR61241B (en)	1978-10-12
NL930035I1 (nl)	1993-08-02
CH622779A5 (en)	1981-04-30

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BG27362A3 (bg)	1979-10-12	Метод за получаване на n-фенил-n-бензоил-карбамиди
BG27542A3 (bg)	1979-11-12	Метод за получаване на 1-бензазолилалкил-4-заместени пиперидини
BG24809A3 (bg)	1978-05-12	Метод за получаване на бензизотиазолони
BG24799A3 (bg)	1978-05-12	Метод за получаване на бензоилуреидо-дифенилетери
DK376276A (da)	1977-02-21	Fremgangsmade til fremstilling af alfa-aminosyreamid
BG27355A3 (bg)	1979-10-12	Метод за получаване на 11-дезокси-16-арилокси-w-тетранорпростагландини
BG25078A3 (bg)	1978-07-12	Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG27543A3 (bg)	1979-11-12	Метод за получаване на n-арил-n-(1-l-4-пиперидинил)- арилацет-амиди
BG27751A3 (bg)	1979-12-12	Метод за получаване тиоетери на клавулаковата киселина
BG24801A3 (bg)	1978-05-12	Метод за получаване наl-пироглутамилl-пролинамид
BG26535A3 (bg)	1979-04-12	Метод за получаване на индолхинолизини
BG26388A3 (bg)	1979-03-15	Метод за получаване на производни на ксантеновата киселина
BG27365A3 (bg)	1979-10-12	Метод за получаване на разтвори на перпропионовата киселина
SE431980B (sv)	1984-03-12	Forfarande for framstellning av tiokarbamidsyraestrar
BG26534A4 (bg)	1979-04-12	Метод за получаване на 2-метил-2-цианометил-5- изопропилтетрахидрофуран
BG27364A3 (bg)	1979-10-12	Метод за получаване на разтвори на перпропионовата киселина
PT65607A (de)	1976-10-01	Verfahren zur herstellung von anthelminthisch wirksamen 2-carbalkoxyamino-5(6)-pheny-sulfonyloxy-benzimidazolen
BG24945A3 (bg)	1978-06-15	Метод за получаване на естери на пентахалогенфенилмалоновата киселина
SE413314B (sv)	1980-05-19	Forfarande for framstellning av o-(2,6-dikloroanilino)fenylettiksyra
SU534472A1 (ru)	1976-11-05	Способ получени полиорганонитрилсилоксанов
SU521251A1 (ru)	1976-07-15	Способ получени дибензоилнафталиндикарбоновой кислоты
SU525676A1 (ru)	1976-08-25	Способ получени -алкил/арил/4-формил-5-хлоримидазолов
BG24228A3 (bg)	1978-01-10	Метод за получаване на n-алкенил-2-аминометил-пирамидини