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BG24803A3 - Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина - Google Patents

Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина

Info

Publication number
BG24803A3
BG24803A3 BG035343A BG3534376A BG24803A3 BG 24803 A3 BG24803 A3 BG 24803A3 BG 035343 A BG035343 A BG 035343A BG 3534376 A BG3534376 A BG 3534376A BG 24803 A3 BG24803 A3 BG 24803A3
Authority
BG
Bulgaria
Prior art keywords
dihydropyridine
methoxycarbonyl
nitrophenyl
dimethyl
obtaining
Prior art date
Application number
BG035343A
Other languages
Bulgarian (bg)
English (en)
Inventor
Egbert Wehinger
Friedrich Bossert
Arent Heise
Stanislav Karda
Kurt Stoepel
Wall Vater
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG24803A3 publication Critical patent/BG24803A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG035343A 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина BG24803A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG24803A3 true BG24803A3 (bg) 1978-05-12

Family

ID=5960951

Family Applications (6)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035344A BG24804A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035343A BG24803A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил 4-(2'-нитрофенил)-1,4-дихидропиридин -5-карбоновата киселина
BG035342A BG25079A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина
BG034575A BG24668A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина
BG035345A BG24805A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BG035341A BG25078A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина
BG035344A BG24804A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина

Family Applications After (3)

Application Number Title Priority Date Filing Date
BG035342A BG25079A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4-(2'-нитрофенил)-1,4 дихидропиридин-5-карбоновата киселина
BG034575A BG24668A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2-6-диметил-3- метоксикарбонил-4-(2'-нитрофенил)-1,4-дихидропиридин-5- карбоновата киселина
BG035345A BG24805A3 (bg) 1975-11-05 1976-11-01 Метод за получаване на изобутилов естер на 2,6-диметил-3-метоксикарбонил -4(2'-нитрофенил)-1,4-дихидропиридин-5-карбоновата киселина

Country Status (27)

Country Link
JP (1) JPS5259161A (xx)
AT (1) AT352129B (xx)
AU (1) AU498964B2 (xx)
BE (1) BE847968A (xx)
BG (6) BG25078A3 (xx)
CA (1) CA1085406A (xx)
CH (2) CH623038A5 (xx)
CS (1) CS200499B2 (xx)
DE (1) DE2549568C3 (xx)
DK (1) DK146762C (xx)
ES (2) ES452986A1 (xx)
FI (1) FI60704C (xx)
FR (1) FR2330395A1 (xx)
GB (1) GB1516793A (xx)
GR (1) GR61241B (xx)
HK (1) HK12681A (xx)
IE (1) IE43984B1 (xx)
IL (1) IL50817A (xx)
LU (2) LU76133A1 (xx)
NL (2) NL175915C (xx)
NO (1) NO145574C (xx)
NZ (1) NZ182502A (xx)
PL (2) PL105940B1 (xx)
PT (1) PT65797B (xx)
RO (1) RO70295A (xx)
SE (1) SE423542B (xx)
ZA (1) ZA766622B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社 扉
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
PT65797B (de) 1978-05-12
ES452986A1 (es) 1977-12-16
BG24668A3 (bg) 1978-04-12
BG24804A3 (bg) 1978-05-12
NL175915C (nl) 1985-01-16
PL105940B1 (pl) 1979-11-30
HK12681A (en) 1981-04-10
JPS5647185B2 (xx) 1981-11-07
IE43984L (en) 1977-05-05
AU498964B2 (en) 1979-03-29
NO763608L (xx) 1977-05-06
GR61241B (en) 1978-10-12
IL50817A (en) 1979-07-25
ES463166A1 (es) 1978-07-16
DE2549568C3 (de) 1981-10-29
NL7612198A (nl) 1977-05-09
SE423542B (sv) 1982-05-10
CA1085406A (en) 1980-09-09
BE847968A (fr) 1977-05-04
IL50817A0 (en) 1977-01-31
NL930035I1 (nl) 1993-08-02
NL930035I2 (nl) 1993-10-01
AU1935876A (en) 1978-05-11
LU76133A1 (xx) 1977-06-02
FI60704C (fi) 1982-03-10
AT352129B (de) 1979-09-10
DK498476A (da) 1977-05-06
ZA766622B (en) 1977-10-26
BG25079A3 (bg) 1978-07-12
DE2549568A1 (de) 1977-05-18
FI60704B (fi) 1981-11-30
LU88275I2 (xx) 1994-02-03
CS200499B2 (en) 1980-09-15
DE2549568B2 (de) 1980-08-21
GB1516793A (en) 1978-07-05
BG24805A3 (bg) 1978-05-12
PL106084B1 (pl) 1979-11-30
FR2330395B1 (xx) 1978-12-22
FR2330395A1 (fr) 1977-06-03
CH622779A5 (en) 1981-04-30
FI763160A7 (xx) 1977-05-06
IE43984B1 (en) 1981-07-15
NO145574B (no) 1982-01-11
SE7612308L (sv) 1977-05-06
DK146762B (da) 1983-12-27
NZ182502A (en) 1978-07-28
DK146762C (da) 1984-06-12
JPS5259161A (en) 1977-05-16
PT65797A (de) 1976-12-01
CH623038A5 (en) 1981-05-15
ATA814276A (de) 1979-02-15
RO70295A (ro) 1981-08-17
BG25078A3 (bg) 1978-07-12
NO145574C (no) 1982-04-21

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