BG105557A - Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants - Google Patents

Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

Info

Publication number: BG105557A
Authority: BG; Bulgaria
Prior art keywords: coagulants; aryl; pyrimidine derivatives; heterocyclyl substituted; substituted pyrimidine
Prior art date: 1998-12-04

Application number

BG105557A

Other languages

Bulgarian (bg)

English (en)

Inventor

David Davey

Gary Phillips

Original Assignee

Berlex Laboratories, Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-04

Filing date

2001-06-01

Publication date

2001-12-29

2001-06-01 Application filed by Berlex Laboratories, Inc filed Critical Berlex Laboratories, Inc

2001-12-29 Publication of BG105557A publication Critical patent/BG105557A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Oncology (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Separation Of Suspended Particles By Flocculating Agents (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG105557A 1998-12-04 2001-06-01 Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants BG105557A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/205,498 US6127376A (en)	1998-12-04	1998-12-04	Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
PCT/US1999/028537 WO2000033844A1 (en)	1998-12-04	1999-12-03	Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

Publications (1)

Publication Number	Publication Date
BG105557A true BG105557A (en)	2001-12-29

Family

ID=22762435

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105557A BG105557A (en)	1998-12-04	2001-06-01	Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants

Country Status (26)

Country	Link
US (2)	US6127376A (no)
EP (1)	EP1135131A4 (no)
JP (1)	JP2002531506A (no)
KR (1)	KR20010093799A (no)
CN (1)	CN1329491A (no)
AU (1)	AU760370B2 (no)
BG (1)	BG105557A (no)
BR (1)	BR9915938A (no)
CA (1)	CA2354040A1 (no)
CZ (1)	CZ20011932A3 (no)
EE (1)	EE200100298A (no)
HR (1)	HRP20010499A2 (no)
HU (1)	HUP0104508A3 (no)
IL (2)	IL143347A0 (no)
LT (1)	LT4912B (no)
LV (1)	LV12783B (no)
MX (1)	MXPA01005656A (no)
NO (1)	NO20012701L (no)
NZ (1)	NZ512104A (no)
PL (1)	PL348034A1 (no)
RO (1)	RO120971B1 (no)
RU (1)	RU2001118466A (no)
SI (1)	SI20637A (no)
SK (1)	SK7632001A3 (no)
WO (1)	WO2000033844A1 (no)
ZA (1)	ZA200104235B (no)

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WO2005047268A2 (en) *	2003-11-10	2005-05-26	X-Ceptor Therapeutics, Inc.	Substituted pyrimidine compositions and methods of use
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US8932842B2 (en)	2009-02-11	2015-01-13	Northwestern University	Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition
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KR101705158B1 (ko)	2009-05-05	2017-02-09	다나-파버 캔서 인스티튜트 인크.	Ｅｇｆｒ 억제제 및 질환 치료방법
RU2013109393A (ru)	2010-08-10	2014-09-20	Сэлджин Авиаломикс Ресеарч, Инк.	Безилатная соль ингибитора втк
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EP2635285B1 (en)	2010-11-01	2017-05-03	Celgene Avilomics Research, Inc.	Heteroaryl compounds and uses thereof
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EP2782579B1 (en)	2011-11-23	2019-01-02	Portola Pharmaceuticals, Inc.	Pyrazine kinase inhibitors
RU2711077C9 (ru)	2012-03-15	2020-08-11	Селджен Кар Ллс	Соли ингибитора киназы рецептора эпидермального фактора роста
BR112014022789B1 (pt)	2012-03-15	2022-04-19	Celgene Car Llc	Formas sólidas de um inibidor de quinase de receptor do fator de crescimento epidérmico, composição farmacêutica e usos do mesmo
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1998
- 1998-12-04 US US09/205,498 patent/US6127376A/en not_active Expired - Fee Related
1999
- 1999-12-03 IL IL14334799A patent/IL143347A0/xx active IP Right Grant
- 1999-12-03 EP EP99965087A patent/EP1135131A4/en not_active Withdrawn
- 1999-12-03 MX MXPA01005656A patent/MXPA01005656A/es not_active IP Right Cessation
- 1999-12-03 HR HR20010499A patent/HRP20010499A2/hr not_active Application Discontinuation
- 1999-12-03 CN CN99814024A patent/CN1329491A/zh active Pending
- 1999-12-03 PL PL99348034A patent/PL348034A1/xx not_active Application Discontinuation
- 1999-12-03 JP JP2000586336A patent/JP2002531506A/ja active Pending
- 1999-12-03 AU AU31075/00A patent/AU760370B2/en not_active Ceased
- 1999-12-03 CZ CZ20011932A patent/CZ20011932A3/cs unknown
- 1999-12-03 SI SI9920090A patent/SI20637A/sl not_active IP Right Cessation
- 1999-12-03 CA CA002354040A patent/CA2354040A1/en not_active Abandoned
- 1999-12-03 RU RU2001118466/14A patent/RU2001118466A/ru not_active Application Discontinuation
- 1999-12-03 HU HU0104508A patent/HUP0104508A3/hu unknown
- 1999-12-03 BR BR9915938-4A patent/BR9915938A/pt not_active IP Right Cessation
- 1999-12-03 KR KR1020017006934A patent/KR20010093799A/ko not_active Withdrawn
- 1999-12-03 EE EEP200100298A patent/EE200100298A/xx unknown
- 1999-12-03 SK SK763-2001A patent/SK7632001A3/sk unknown
- 1999-12-03 NZ NZ512104A patent/NZ512104A/en unknown
- 1999-12-03 WO PCT/US1999/028537 patent/WO2000033844A1/en not_active Ceased
- 1999-12-03 RO ROA200100606A patent/RO120971B1/ro unknown
2000
- 2000-03-30 US US09/539,812 patent/US6372751B1/en not_active Expired - Fee Related
2001
- 2001-05-23 ZA ZA200104235A patent/ZA200104235B/en unknown
- 2001-05-24 IL IL143347A patent/IL143347A/en not_active IP Right Cessation
- 2001-06-01 BG BG105557A patent/BG105557A/xx unknown
- 2001-06-01 NO NO20012701A patent/NO20012701L/no not_active Application Discontinuation
- 2001-06-12 LT LT2001061A patent/LT4912B/lt not_active IP Right Cessation
- 2001-07-04 LV LVP-01-100A patent/LV12783B/xx unknown

Also Published As

Publication number	Publication date
IL143347A0 (en)	2002-04-21
NO20012701L (no)	2001-07-25
SK7632001A3 (en)	2001-12-03
BR9915938A (pt)	2001-08-21
US6127376A (en)	2000-10-03
CA2354040A1 (en)	2000-06-15
IL143347A (en)	2006-12-10
LT4912B (lt)	2002-04-25
EE200100298A (et)	2002-12-16
CN1329491A (zh)	2002-01-02
JP2002531506A (ja)	2002-09-24
NO20012701D0 (no)	2001-06-01
CZ20011932A3 (cs)	2001-10-17
LV12783B (en)	2002-10-20
HRP20010499A2 (en)	2003-04-30
NZ512104A (en)	2003-10-31
ZA200104235B (en)	2002-08-23
HUP0104508A2 (hu)	2002-05-29
LT2001061A (en)	2001-12-27
RO120971B1 (ro)	2006-10-30
EP1135131A1 (en)	2001-09-26
KR20010093799A (ko)	2001-10-29
AU3107500A (en)	2000-06-26
US6372751B1 (en)	2002-04-16
EP1135131A4 (en)	2002-01-02
WO2000033844A1 (en)	2000-06-15
SI20637A (sl)	2002-02-28
HUP0104508A3 (en)	2002-07-29
MXPA01005656A (es)	2002-04-24
RU2001118466A (ru)	2003-04-20
PL348034A1 (en)	2002-05-06
LV12783A (en)	2002-01-20
AU760370B2 (en)	2003-05-15

Publication	Publication Date	Title
BG105557A (en)	2001-12-29	Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
AU1676200A (en)	2000-06-13	Polyhydroxylated heterocyclic derivatives as anti-coagulants
AP2001002103A0 (en)	2001-03-31	Substituted phenyl derivatives, their preparation and use.
BG102704A (en)	1999-10-29	Fungicide 2-methoxybenzophenons
MY119800A (en)	2005-07-29	Pyridine derivatives
CA2297911A1 (en)	1999-02-04	Substituted 6-phenylphenanthridines
MY132671A (en)	2007-10-31	Substituted 6,6-hetero-bicyclic derivatives
IL135536A0 (en)	2001-05-20	Ortho-anthranilamide derivatives and pharmaceutical compositions containing the same
BG106444A (en)	2002-09-30	Benzodiazepin derivatives, the production and use thereof
ATE248175T1 (de)	2003-09-15	Epothilonderivate und ihre verwendung als antitumormittel
BG105650A (en)	2002-02-28	Azepinoindole derivatives, the production and use thereof
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