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AU2006259663A1 - Tubulin inhibitor and process for its preparation - Google Patents

Tubulin inhibitor and process for its preparation Download PDF

Info

Publication number
AU2006259663A1
AU2006259663A1 AU2006259663A AU2006259663A AU2006259663A1 AU 2006259663 A1 AU2006259663 A1 AU 2006259663A1 AU 2006259663 A AU2006259663 A AU 2006259663A AU 2006259663 A AU2006259663 A AU 2006259663A AU 2006259663 A1 AU2006259663 A1 AU 2006259663A1
Authority
AU
Australia
Prior art keywords
trifluoro
pyrazin
process according
phenyl
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006259663A
Other languages
English (en)
Inventor
Jay Thomas Afragola
David Michael Blum
Timothy John Doyle
Jean Schmid
Yanzhong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37074929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2006259663(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2006259663A1 publication Critical patent/AU2006259663A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2006259663A 2005-06-13 2006-06-08 Tubulin inhibitor and process for its preparation Abandoned AU2006259663A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69001605P 2005-06-13 2005-06-13
US60/690,016 2005-06-13
US80278106P 2006-05-24 2006-05-24
US60/802,781 2006-05-24
PCT/US2006/022574 WO2006138180A1 (en) 2005-06-13 2006-06-08 Tubulin inhibitor and process for its preparation

Publications (1)

Publication Number Publication Date
AU2006259663A1 true AU2006259663A1 (en) 2006-12-28

Family

ID=37074929

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006259663A Abandoned AU2006259663A1 (en) 2005-06-13 2006-06-08 Tubulin inhibitor and process for its preparation

Country Status (12)

Country Link
EP (1) EP1891052A1 (es)
JP (1) JP2008543838A (es)
AR (1) AR054392A1 (es)
AU (1) AU2006259663A1 (es)
BR (1) BRPI0612145A2 (es)
CA (1) CA2610416A1 (es)
GT (1) GT200600257A (es)
MX (1) MX2007015718A (es)
PE (1) PE20070114A1 (es)
SV (1) SV2007002573A (es)
TW (1) TW200716613A (es)
WO (1) WO2006138180A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102648208B (zh) 2009-11-12 2016-04-27 R&D生技药品有限责任公司 微管蛋白抑制剂
US9649317B2 (en) * 2012-09-19 2017-05-16 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2017181974A1 (zh) * 2016-04-20 2017-10-26 苏州苏领生物医药有限公司 五元杂环类化合物及其制备方法、药物组合物和用途
US11623927B2 (en) 2018-03-02 2023-04-11 The Trustees Of The University Of Pennsylvania Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1663241B1 (en) * 2003-09-24 2009-05-27 Wyeth Holdings Corporation 5-arylpyrimidines as anticancer agents
AU2004276240A1 (en) * 2003-09-24 2005-04-07 Wyeth Holdings Corporation 6-[(substituted)phenyl]triazolopyrimidines as anticancer agents

Also Published As

Publication number Publication date
GT200600257A (es) 2007-02-14
PE20070114A1 (es) 2007-02-03
JP2008543838A (ja) 2008-12-04
SV2007002573A (es) 2007-01-03
AR054392A1 (es) 2007-06-20
TW200716613A (en) 2007-05-01
MX2007015718A (es) 2008-02-21
BRPI0612145A2 (pt) 2010-10-19
WO2006138180A1 (en) 2006-12-28
EP1891052A1 (en) 2008-02-27
CA2610416A1 (en) 2006-12-28

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period