AU2001287725A1 - Intermediates in cephalosporin production - Google Patents

Intermediates in cephalosporin production

Info

Publication number: AU2001287725A1
Authority: AU; Australia
Prior art keywords: intermediates; cephalosporin production; cephalosporin; production
Prior art date: 2000-09-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001287725A

Inventor

Peter Kremminger

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz GmbH

Original Assignee

Biochemie GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-09-11

Filing date

2001-09-10

Publication date

2002-03-22

2001-09-10 Application filed by Biochemie GmbH filed Critical Biochemie GmbH

2002-03-22 Publication of AU2001287725A1 publication Critical patent/AU2001287725A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
- C07D501/06—Acylation of 7-aminocephalosporanic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AU2001287725A 2000-09-11 2001-09-10 Intermediates in cephalosporin production Abandoned AU2001287725A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AT1537/2000		2000-09-11
AT0153700A AT411996B (en)	2000-09-11	2000-09-11	METHOD FOR PRODUCING CEFUROXIME IN THE FORM OF ITS N-BUTYL LAMONIUM SALTS
PCT/EP2001/010447 WO2002020532A1 (en)	2000-09-11	2001-09-10	Intermediates in cephalosporin production

Publications (1)

Publication Number	Publication Date
AU2001287725A1 true AU2001287725A1 (en)	2002-03-22

Family

ID=3688325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001287725A Abandoned AU2001287725A1 (en)	2000-09-11	2001-09-10	Intermediates in cephalosporin production

Country Status (12)

Country	Link
US (1)	US6894162B2 (en)
EP (1)	EP1319009B1 (en)
JP (1)	JP2004508378A (en)
KR (1)	KR100864405B1 (en)
CN (1)	CN1200941C (en)
AT (2)	AT411996B (en)
AU (1)	AU2001287725A1 (en)
CA (1)	CA2419258C (en)
DE (1)	DE60136285D1 (en)
DK (1)	DK1319009T3 (en)
TW (1)	TWI282339B (en)
WO (1)	WO2002020532A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN190849B (en) *	2000-07-17	2003-08-23	Ranbaxy Lab Ltd
US20040092735A1 (en) *	2002-11-08	2004-05-13	Orchid Chemicals & Pharmaceuticals Limited	Process for the preparation of cefuroxime sodium
WO2004050663A2 (en) *	2002-12-05	2004-06-17	Orchid Chemicals & Pharmaceuticals Ltd	An improved process for the preparation of cefuroxime sodium
US7662955B2 (en) *	2003-03-20	2010-02-16	Orchid Chemicals And Pharmaceuticals Ltd.	Process for the preparation of cefoxitin
DE602005017197D1 (en) *	2005-03-29	2009-11-26	Hetero Drugs Ltd	IMPROVED METHOD FOR THE PREPARATION OF CEFIXIM
ITMI20050871A1 (en) *	2005-05-13	2006-11-14	Acs Dobfar Spa	CEFUROXIMA ACID CRYSTALLINE SOLVATE
CN104961749B (en) *	2015-06-15	2016-01-13	海南灵康制药有限公司	A novel industrial crystallization method and preparation of cefuroxime sodium
CN105440052A (en) *	2016-01-13	2016-03-30	广东立国制药有限公司	Preparation method of cefuroxime acid
CN106554361B (en) *	2016-09-30	2018-10-09	华北制药河北华民药业有限责任公司	A kind of preparation method of CEFUROXIME AXETIL oral preparation
CN112745338B (en) *	2020-12-30	2022-08-16	山东金城昆仑药业有限公司	Method for eliminating lactone impurities in cefuroxime acid

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US391589A (en) *		1888-10-23		Variety wood-worker
GB1474519A (en) *	1973-05-14	1977-05-25
US4122259A (en)	1974-08-23	1978-10-24	Glaxo Laboratories Limited	7β-[2-Aryl-2-(etherified oximino)acetamido]-3-N-substituted carbamoyloxymethylceph-3-em-4-carboxylic acids
CA1094545A (en) *	1976-02-16	1981-01-27	Michael Gregson	Cephalosporin antibiotics
GB1575905A (en)	1976-04-28	1980-10-01	Glaxo Lab Ltd	Salt of cefuroxime
GB2018764B (en) *	1978-04-07	1982-09-02	Glaxo Group Ltd	Cephalosporin compounds
DK392779A (en)	1978-09-21	1980-03-22	Glaxo Group Ltd	PROCEDURE FOR MANUFACTURING CEPHALOSPOR COMPOUNDS
DK159449C (en)	1979-02-15	1991-03-04	Glaxo Group Ltd	METHOD FOR PREPARING SODIUM CEFUROXIM
AT367424B (en)	1979-04-06	1982-07-12	Glaxo Group Ltd	METHOD FOR PRODUCING 3-CARBAMOYLOXYMETHYLCEPHALOSPORINE COMPOUNDS
DK165118C (en)	1980-11-22	1993-03-01	Gema Sa	PROCEDURE FOR PREPARING SOLUTIONS OF 7-AMINOCEPHALOSPORANIC ACIDS
YU44680B (en)	1982-07-30	1990-12-31	Glaxo Lab Ltd	Process for obtaining very pure amorphous form of cephuroxim axetile
ES522728A0 (en)	1983-05-26	1985-06-01	Gema Sa	"SALTS OF AMINO-BETA-LACTAMIC ACIDS, FOR ITS APPLICATION TO OBTAIN N-ACIL DERIVED FROM THEM, AND PROCEDURE FOR THE OBTAINING OF SALES SALTS"
GB8320520D0 (en)	1983-07-29	1983-09-01	Glaxo Group Ltd	Chemical process
GB8320521D0 (en)	1983-07-29	1983-09-01	Glaxo Group Ltd	Chemical process
IT1214587B (en)	1986-12-23	1990-01-18	Giovanni Bonfanti	METHOD FOR THE PRODUCTION OF PURE CRYSTALLINE PRODUCTS.
PL151670B1 (en) *	1987-03-19	1990-09-28		Method for manufacturing semisynthetic cephalosporins
JP3121903B2 (en)	1992-02-07	2001-01-09	塩野義製薬株式会社	Method for Carbamoylation of Deacetylcephalosporanic Acid
AT400717B (en)	1993-07-30	1996-03-25	Biochemie Gmbh	NEW GUANIDINE AND AMIDINE SALT OF 7-AMINO-3-HYDROXYMETHYL-3-CEPHEM-4-CARBONIC ACID
WO2000053609A1 (en)	1999-03-09	2000-09-14	Ranbaxy Laboratories Limited	Process for the preparation of cefuroxime
IT1313569B1 (en)	1999-07-27	2002-09-09	Antibioticos Spa	PROCESS FOR THE SYNTHESIS OF BETA-LACTAMIC DERIVATIVES.
IN190849B (en) *	2000-07-17	2003-08-23	Ranbaxy Lab Ltd

2000
- 2000-09-11 AT AT0153700A patent/AT411996B/en not_active IP Right Cessation
2001
- 2001-09-10 KR KR1020037002344A patent/KR100864405B1/en not_active Expired - Fee Related
- 2001-09-10 DE DE60136285T patent/DE60136285D1/en not_active Expired - Lifetime
- 2001-09-10 US US10/363,962 patent/US6894162B2/en not_active Expired - Fee Related
- 2001-09-10 CA CA002419258A patent/CA2419258C/en not_active Expired - Fee Related
- 2001-09-10 AU AU2001287725A patent/AU2001287725A1/en not_active Abandoned
- 2001-09-10 DK DK01967326T patent/DK1319009T3/en active
- 2001-09-10 WO PCT/EP2001/010447 patent/WO2002020532A1/en not_active Ceased
- 2001-09-10 AT AT01967326T patent/ATE412001T1/en not_active IP Right Cessation
- 2001-09-10 CN CNB018154212A patent/CN1200941C/en not_active Expired - Fee Related
- 2001-09-10 JP JP2002525153A patent/JP2004508378A/en not_active Withdrawn
- 2001-09-10 EP EP01967326A patent/EP1319009B1/en not_active Expired - Lifetime
- 2001-09-10 TW TW090122340A patent/TWI282339B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
US6894162B2 (en)	2005-05-17
EP1319009B1 (en)	2008-10-22
CA2419258C (en)	2009-12-29
TWI282339B (en)	2007-06-11
JP2004508378A (en)	2004-03-18
ATE412001T1 (en)	2008-11-15
AT411996B (en)	2004-08-26
HK1057542A1 (en)	2004-04-08
CA2419258A1 (en)	2002-03-14
KR100864405B1 (en)	2008-10-20
DK1319009T3 (en)	2009-02-16
EP1319009A1 (en)	2003-06-18
US20030171577A1 (en)	2003-09-11
ATA15372000A (en)	2004-01-15
CN1200941C (en)	2005-05-11
CN1454212A (en)	2003-11-05
KR20030040404A (en)	2003-05-22
WO2002020532A1 (en)	2002-03-14
DE60136285D1 (en)	2008-12-04

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