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ATE498135T1 - Homogener doppelrezeptor-agglutinationstest für immunsuppressiva - Google Patents

Homogener doppelrezeptor-agglutinationstest für immunsuppressiva

Info

Publication number
ATE498135T1
ATE498135T1 AT07786032T AT07786032T ATE498135T1 AT E498135 T1 ATE498135 T1 AT E498135T1 AT 07786032 T AT07786032 T AT 07786032T AT 07786032 T AT07786032 T AT 07786032T AT E498135 T1 ATE498135 T1 AT E498135T1
Authority
AT
Austria
Prior art keywords
immunosupressives
agglutination test
receptor
homogeneous
dual receptor
Prior art date
Application number
AT07786032T
Other languages
English (en)
Inventor
Gerald Sigler
Mitali Ghoshal
Shaker Rashid
Yifei Wu
Allan Dorn
Jane Tsai
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE498135T1 publication Critical patent/ATE498135T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07786032T 2006-07-13 2007-07-12 Homogener doppelrezeptor-agglutinationstest für immunsuppressiva ATE498135T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80724506P 2006-07-13 2006-07-13
US11/772,886 US20080081379A1 (en) 2006-07-13 2007-07-03 Homogeneous double receptor agglutination assay for immunosuppressant drugs
PCT/EP2007/006200 WO2008006588A1 (en) 2006-07-13 2007-07-12 Homogeneous double receptor agglutination assay for immunosuppressant drugs

Publications (1)

Publication Number Publication Date
ATE498135T1 true ATE498135T1 (de) 2011-02-15

Family

ID=38535540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07786032T ATE498135T1 (de) 2006-07-13 2007-07-12 Homogener doppelrezeptor-agglutinationstest für immunsuppressiva

Country Status (7)

Country Link
US (1) US20080081379A1 (de)
EP (1) EP2041580B1 (de)
JP (1) JP2009543084A (de)
AT (1) ATE498135T1 (de)
CA (1) CA2657588A1 (de)
DE (1) DE602007012439D1 (de)
WO (1) WO2008006588A1 (de)

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Publication number Priority date Publication date Assignee Title
WO2009025475A2 (en) * 2007-08-17 2009-02-26 Korea Advanced Institute Of Science And Technology The methods for detecting molecular interactions
JP5646457B2 (ja) 2008-04-29 2014-12-24 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリン及びその使用
NZ589434A (en) 2008-06-03 2012-11-30 Abbott Lab Dual variable domain immunoglobulins and uses thereof
JP5908396B2 (ja) 2009-04-21 2016-04-26 イミュノライト・エルエルシー ｉｎｓｉｔｕフォトバイオモジュレーションのための、非侵襲的エネルギーアップコンバージョン方法およびシステム
UY33492A (es) 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
SG188190A1 (en) 2010-08-03 2013-04-30 Abbott Lab Dual variable domain immunoglobulins and uses thereof
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
EP3974831A1 (de) 2010-10-22 2022-03-30 T2 Biosystems, Inc. Verfahren zum nachweis eines bakteriums in einer vollblutprobe
WO2013158281A1 (en) 2012-04-20 2013-10-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
EP3243078A1 (de) 2015-01-09 2017-11-15 Atonomics A/S Universelles assay zur bestimmung der menge von tnf-hemmenden arzneimitteln und zugehörige antiwirkstoff-antikörper
WO2017127731A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Nmr methods and systems for the rapid detection of bacteria
JP2019522199A (ja) * 2016-07-08 2019-08-08 アトノミックス アクティーゼルスカブ 試料中の治療用モノクローナル抗体及びそれらの対応する抗薬物抗体の量を確定するためのユニバーサルアッセイ
JP7206214B2 (ja) 2016-12-13 2023-01-17 シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート） インビトロ及びインビボで操作された細胞において発現された化学誘導シグナル伝達複合体の外因性薬物活性化の方法
CA3091490A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Rapamycin resistant cells
EP3990923A4 (de) * 2019-06-28 2022-08-31 Siemens Healthcare Diagnostics, Inc. Reagenzien für sandwich-immunoassays unter verwendung von verbesserter agglutinationsdetektion mittels partikeln sowie verfahren zur herstellung und verwendung davon
JP2024113375A (ja) * 2023-02-09 2024-08-22 日本光電工業株式会社 試料中の測定対象物を検出する免疫測定方法

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JPH032565A (ja) * 1989-05-30 1991-01-08 Olympus Optical Co Ltd 免疫学的分析方法
EP0487289B1 (de) * 1990-11-20 1996-09-04 BEHRINGWERKE Aktiengesellschaft Immunotest für Cyclosporin
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
WO1995004069A1 (en) * 1993-07-30 1995-02-09 Affymax Technologies N.V. Biotinylation of proteins
US6187547B1 (en) 1993-09-08 2001-02-13 Novartis Ag Assay kit
JP3292766B2 (ja) * 1993-09-20 2002-06-17 積水化学工業株式会社 糖化蛋白の測定方法
CN1147853A (zh) * 1994-03-10 1997-04-16 藤泽药品工业株式会社 免疫抑制剂的定量法
US6150137A (en) * 1994-05-27 2000-11-21 Ariad Pharmaceuticals, Inc. Immunosuppressant target proteins
US5922551A (en) * 1997-03-20 1999-07-13 Accumetrics, Inc. Agglutrimetric platelet binding assays in blood
US6709873B1 (en) * 1997-04-09 2004-03-23 Isodiagnostika Inc. Method for production of antibodies to specific sites of rapamycin
JP3513075B2 (ja) * 2000-04-05 2004-03-31 デンカ生研株式会社 免疫測定法及びそのための試薬
EP1239285A1 (de) 2001-03-07 2002-09-11 Roche Diagnostics GmbH Verbesserte Methode für ein homogenes Immunotestverfahren
US20030003503A1 (en) * 2001-06-29 2003-01-02 Tsai Tenlin S. Enhancing sensitivity and equimolar detection through modifications of the reaction environment
WO2005062708A2 (en) 2003-12-29 2005-07-14 Ramot At Tel-Aviv University Ltd. An assay for the detection of rapamycin and rapamycin analogs
WO2005088307A1 (en) 2004-03-10 2005-09-22 Seradyn Inc. Immunoassays for everolimus
US8021849B2 (en) * 2004-11-05 2011-09-20 Siemens Healthcare Diagnostics Inc. Methods and kits for the determination of sirolimus in a sample
EP2180323B1 (de) 2005-04-06 2012-02-01 Abbott Laboratories Verfahren zur Messung immunsuppressiver Tacrolimus-, Sirolimus- und Cyclosporin-A-Komplexe in einer Blutprobe
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7642059B2 (en) * 2005-09-07 2010-01-05 Roche Diagnostics Operations, Inc. Single receptor assays for immunosuppressive drugs

Also Published As

Publication number Publication date
DE602007012439D1 (de) 2011-03-24
EP2041580A1 (de) 2009-04-01
EP2041580B1 (de) 2011-02-09
US20080081379A1 (en) 2008-04-03
JP2009543084A (ja) 2009-12-03
CA2657588A1 (en) 2008-01-17
WO2008006588A1 (en) 2008-01-17

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