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MX2012004833A - Analisis para detectar anticuerpos especificos a anticuerpos anti-ige terapeuticos y su uso en anafilaxis. - Google Patents

Analisis para detectar anticuerpos especificos a anticuerpos anti-ige terapeuticos y su uso en anafilaxis.

Info

Publication number
MX2012004833A
MX2012004833A MX2012004833A MX2012004833A MX2012004833A MX 2012004833 A MX2012004833 A MX 2012004833A MX 2012004833 A MX2012004833 A MX 2012004833A MX 2012004833 A MX2012004833 A MX 2012004833A MX 2012004833 A MX2012004833 A MX 2012004833A
Authority
MX
Mexico
Prior art keywords
anaphylaxis
therapeutic anti
assays
ige
antibodies
Prior art date
Application number
MX2012004833A
Other languages
English (en)
Other versions
MX344935B (es
Inventor
Henry B Lowman
Saloumeh Fischer
Dana L Baker
Gerald R Nakamura
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2012004833A publication Critical patent/MX2012004833A/es
Publication of MX344935B publication Critical patent/MX344935B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La invención prove métodos y reactivos útiles para detectar anticuerpos anti-fármaco de isotipo IgE para anticuerpos anti-IgE terapéuticos y métodos para determinar el riesgo de anafilaxis a la administración de un anticuerpo anti-IgE terapéutico.
MX2012004833A 2009-10-26 2010-10-26 Analisis para detectar anticuerpos especificos a anticuerpos anti-ige terapeuticos y su uso en anafilaxis. MX344935B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25505209P 2009-10-26 2009-10-26
PCT/US2010/054160 WO2011056606A1 (en) 2009-10-26 2010-10-26 Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis

Publications (2)

Publication Number Publication Date
MX2012004833A true MX2012004833A (es) 2012-07-04
MX344935B MX344935B (es) 2017-01-11

Family

ID=43970265

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012004833A MX344935B (es) 2009-10-26 2010-10-26 Analisis para detectar anticuerpos especificos a anticuerpos anti-ige terapeuticos y su uso en anafilaxis.

Country Status (18)

Country Link
US (1) US9315583B2 (es)
EP (1) EP2494356B1 (es)
JP (1) JP6139885B2 (es)
KR (1) KR101832510B1 (es)
CN (1) CN102695956B (es)
AU (1) AU2010315470B2 (es)
BR (1) BR112012009846B8 (es)
CA (1) CA2778810C (es)
DK (1) DK2494356T3 (es)
HU (1) HUE033492T2 (es)
IL (1) IL219337A (es)
MX (1) MX344935B (es)
MY (1) MY182750A (es)
NZ (1) NZ599600A (es)
RU (1) RU2642295C2 (es)
SI (1) SI2494356T1 (es)
WO (1) WO2011056606A1 (es)
ZA (1) ZA201202999B (es)

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CN112285351A (zh) * 2019-07-22 2021-01-29 上海益诺思生物技术股份有限公司 一种抗IgE单抗的ELISA检测方法
CN110358738B (zh) * 2019-08-22 2021-08-13 中国食品药品检定研究院 一种稳定测定抗IgE抗体药物生物学活性的方法
US20230393144A1 (en) * 2020-10-14 2023-12-07 I-Mab Biopharma Us Limited Methods for mitigating interference by therapeutic anti-cd47 antibodies in pre-transfusion assays
JP7062803B1 (ja) * 2021-03-31 2022-05-06 積水メディカル株式会社 抗薬物抗体測定方法
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
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Also Published As

Publication number Publication date
JP6139885B2 (ja) 2017-05-31
CN102695956B (zh) 2015-12-09
AU2010315470A1 (en) 2012-05-24
EP2494356A1 (en) 2012-09-05
MX344935B (es) 2017-01-11
IL219337A0 (en) 2012-06-28
KR101832510B1 (ko) 2018-02-26
EP2494356B1 (en) 2017-03-15
BR112012009846B8 (pt) 2021-05-25
BR112012009846A2 (pt) 2017-02-21
EP2494356A4 (en) 2013-07-03
RU2012121559A (ru) 2013-12-10
HUE033492T2 (en) 2017-12-28
MY182750A (en) 2021-02-05
CN102695956A (zh) 2012-09-26
US20110183363A1 (en) 2011-07-28
SI2494356T1 (sl) 2017-07-31
NZ599600A (en) 2015-04-24
DK2494356T3 (en) 2017-05-15
CA2778810C (en) 2018-09-04
AU2010315470B2 (en) 2016-05-05
BR112012009846B1 (pt) 2021-04-20
ZA201202999B (en) 2013-06-26
JP2013508740A (ja) 2013-03-07
HK1175538A1 (zh) 2013-07-05
IL219337A (en) 2017-06-29
CA2778810A1 (en) 2011-05-12
RU2642295C2 (ru) 2018-01-24
KR20120116400A (ko) 2012-10-22
WO2011056606A8 (en) 2012-05-18
WO2011056606A1 (en) 2011-05-12
US9315583B2 (en) 2016-04-19

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