ATE489364T1 - Hemmer der zytosolen phospholipase a2 - Google Patents

Hemmer der zytosolen phospholipase a2

Info

Publication number: ATE489364T1
Authority: AT; Austria
Prior art keywords: inhibitors; cytosolic phospholipase; cytosolic; phospholipase
Prior art date: 2005-05-27

Application number

AT06771540T

Other languages

English (en)

Inventor

John Mckew

Katherine Lee

Lihren Chen

Richard Vargas

James Clark

Cara Williams

Valerie Clerin

Suzana Marusic

Kevin Pong

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-05-27

Filing date

2006-05-26

Publication date

2010-12-15

2006-05-26 Application filed by Wyeth Llc filed Critical Wyeth Llc

2010-12-15 Application granted granted Critical

2010-12-15 Publication of ATE489364T1 publication Critical patent/ATE489364T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pulmonology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Obesity (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT06771540T 2005-05-27 2006-05-26 Hemmer der zytosolen phospholipase a2 ATE489364T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68556405P	2005-05-27	2005-05-27
PCT/US2006/020847 WO2006128142A2 (en)	2005-05-27	2006-05-26	Inhibitors of cytosolic phospholipase a2

Publications (1)

Publication Number	Publication Date
ATE489364T1 true ATE489364T1 (de)	2010-12-15

Family

ID=37188759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06771540T ATE489364T1 (de)	2005-05-27	2006-05-26	Hemmer der zytosolen phospholipase a2

Country Status (32)

Country	Link
US (3)	US7557135B2 (de)
EP (2)	EP2248801A1 (de)
JP (1)	JP5116666B2 (de)
KR (1)	KR101353982B1 (de)
CN (2)	CN102040550B (de)
AR (1)	AR054195A1 (de)
AT (1)	ATE489364T1 (de)
AU (1)	AU2006251946B2 (de)
BR (1)	BRPI0610049A2 (de)
CA (1)	CA2607857C (de)
CR (1)	CR9520A (de)
CY (1)	CY1111151T1 (de)
DE (1)	DE602006018451D1 (de)
DK (1)	DK1891006T3 (de)
ES (1)	ES2354908T3 (de)
GT (1)	GT200600228A (de)
HN (1)	HN2006019513A (de)
IL (1)	IL186912A (de)
MX (1)	MX2007014589A (de)
MY (1)	MY144672A (de)
NI (1)	NI200700287A (de)
NO (1)	NO20075627L (de)
NZ (1)	NZ563736A (de)
PE (1)	PE20061426A1 (de)
PL (1)	PL1891006T3 (de)
PT (1)	PT1891006E (de)
RU (1)	RU2433997C2 (de)
SI (1)	SI1891006T1 (de)
SV (1)	SV2008002551A (de)
TW (1)	TW200718687A (de)
UA (1)	UA91053C2 (de)
WO (1)	WO2006128142A2 (de)

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2006
- 2006-05-25 TW TW095118534A patent/TW200718687A/zh unknown
- 2006-05-25 GT GT200600228A patent/GT200600228A/es unknown
- 2006-05-26 BR BRPI0610049-0A patent/BRPI0610049A2/pt not_active IP Right Cessation
- 2006-05-26 AT AT06771540T patent/ATE489364T1/de active
- 2006-05-26 ES ES06771540T patent/ES2354908T3/es active Active
- 2006-05-26 KR KR1020077027672A patent/KR101353982B1/ko not_active Expired - Fee Related
- 2006-05-26 CA CA2607857A patent/CA2607857C/en active Active
- 2006-05-26 AU AU2006251946A patent/AU2006251946B2/en not_active Ceased
- 2006-05-26 PE PE2006000559A patent/PE20061426A1/es not_active Application Discontinuation
- 2006-05-26 US US11/442,199 patent/US7557135B2/en active Active
- 2006-05-26 UA UAA200713220A patent/UA91053C2/ru unknown
- 2006-05-26 SI SI200630865T patent/SI1891006T1/sl unknown
- 2006-05-26 PT PT06771540T patent/PT1891006E/pt unknown
- 2006-05-26 CN CN2010105355308A patent/CN102040550B/zh not_active Expired - Fee Related
- 2006-05-26 PL PL06771540T patent/PL1891006T3/pl unknown
- 2006-05-26 RU RU2007140910/04A patent/RU2433997C2/ru not_active IP Right Cessation
- 2006-05-26 MX MX2007014589A patent/MX2007014589A/es active IP Right Grant
- 2006-05-26 EP EP10172388A patent/EP2248801A1/de not_active Withdrawn
- 2006-05-26 HN HN2006019513A patent/HN2006019513A/es unknown
- 2006-05-26 CN CN2006800186466A patent/CN101184729B/zh not_active Expired - Fee Related
- 2006-05-26 DK DK06771540.9T patent/DK1891006T3/da active
- 2006-05-26 WO PCT/US2006/020847 patent/WO2006128142A2/en not_active Ceased
- 2006-05-26 DE DE602006018451T patent/DE602006018451D1/de active Active
- 2006-05-26 JP JP2008513819A patent/JP5116666B2/ja not_active Expired - Fee Related
- 2006-05-26 NZ NZ563736A patent/NZ563736A/en not_active IP Right Cessation
- 2006-05-26 MY MYPI20062443A patent/MY144672A/en unknown
- 2006-05-26 AR ARP060102198A patent/AR054195A1/es not_active Application Discontinuation
- 2006-05-26 EP EP06771540A patent/EP1891006B1/de not_active Not-in-force
- 2006-05-26 SV SV2006002551A patent/SV2008002551A/es unknown
2007
- 2007-10-25 IL IL186912A patent/IL186912A/en active IP Right Grant
- 2007-11-06 NO NO20075627A patent/NO20075627L/no not_active Application Discontinuation
- 2007-11-09 NI NI200700287A patent/NI200700287A/es unknown
- 2007-11-14 CR CR9520A patent/CR9520A/es not_active Application Discontinuation
2009
- 2009-06-19 US US12/488,020 patent/US20100029645A1/en not_active Abandoned
- 2009-06-19 US US12/488,182 patent/US8283373B2/en active Active
2010
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Also Published As

Publication number	Publication date
NI200700287A (es)	2008-05-27
CR9520A (es)	2008-02-20
US7557135B2 (en)	2009-07-07
CN102040550A (zh)	2011-05-04
GT200600228A (es)	2006-12-26
TW200718687A (en)	2007-05-16
WO2006128142A8 (en)	2007-12-27
US20100029645A1 (en)	2010-02-04
PE20061426A1 (es)	2007-01-24
JP5116666B2 (ja)	2013-01-09
DK1891006T3 (da)	2011-01-24
PL1891006T3 (pl)	2011-05-31
RU2433997C2 (ru)	2011-11-20
HK1152710A1 (en)	2012-03-09
CA2607857A1 (en)	2006-11-30
AR054195A1 (es)	2007-06-06
SV2008002551A (es)	2008-07-23
DE602006018451D1 (de)	2011-01-05
WO2006128142A3 (en)	2007-03-29
BRPI0610049A2 (pt)	2010-05-25
CN101184729B (zh)	2011-02-16
US20070004719A1 (en)	2007-01-04
US8283373B2 (en)	2012-10-09
HK1113680A1 (en)	2008-10-10
AU2006251946B2 (en)	2011-05-12
IL186912A0 (en)	2008-02-09
NZ563736A (en)	2010-11-26
RU2007140910A (ru)	2009-07-10
CA2607857C (en)	2014-02-11
KR101353982B1 (ko)	2014-02-18
MX2007014589A (es)	2008-01-21
CN101184729A (zh)	2008-05-21
MY144672A (en)	2011-10-31
NO20075627L (no)	2008-01-03
WO2006128142A2 (en)	2006-11-30
UA91053C2 (en)	2010-06-25
PT1891006E (pt)	2011-01-26
US20100022536A1 (en)	2010-01-28
HN2006019513A (es)	2011-03-02
EP2248801A1 (de)	2010-11-10
JP2008542303A (ja)	2008-11-27
AU2006251946A1 (en)	2006-11-30
CN102040550B (zh)	2012-10-03
ES2354908T3 (es)	2011-03-21
SI1891006T1 (sl)	2011-02-28
EP1891006A2 (de)	2008-02-27
EP1891006B1 (de)	2010-11-24
IL186912A (en)	2012-05-31
CY1111151T1 (el)	2015-06-11
KR20080021618A (ko)	2008-03-07

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