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DK1943243T3 - Kinase-inhibitorer - Google Patents

Kinase-inhibitorer

Info

Publication number
DK1943243T3
DK1943243T3 DK06826650.1T DK06826650T DK1943243T3 DK 1943243 T3 DK1943243 T3 DK 1943243T3 DK 06826650 T DK06826650 T DK 06826650T DK 1943243 T3 DK1943243 T3 DK 1943243T3
Authority
DK
Denmark
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
DK06826650.1T
Other languages
English (en)
Inventor
Jolie Anne Bastian
De Blas Jesus Andres Blas
Dios Alfonso De
Kevin John Hudziak
Tiechao Li
Mary Margaret Mader
Michael Ray Myers
Mark Andrew Pobanz
Chuan Shih
Boyu Zhong
De Uralde-Garmendia Beatriz Lopez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43298635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1943243(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1943243T3 publication Critical patent/DK1943243T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK06826650.1T 2005-10-28 2006-10-25 Kinase-inhibitorer DK1943243T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73160405P 2005-10-28 2005-10-28
EP06380151 2006-06-02
US82196306P 2006-08-10 2006-08-10
PCT/US2006/041644 WO2007053394A1 (en) 2005-10-28 2006-10-25 Kinase inhibitors

Publications (1)

Publication Number Publication Date
DK1943243T3 true DK1943243T3 (da) 2011-03-07

Family

ID=43298635

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06826650.1T DK1943243T3 (da) 2005-10-28 2006-10-25 Kinase-inhibitorer

Country Status (19)

Country Link
US (1) US7652015B2 (da)
EP (1) EP1943243B1 (da)
KR (1) KR101004156B1 (da)
AR (1) AR056582A1 (da)
AT (1) ATE493403T1 (da)
AU (1) AU2006309044B2 (da)
BR (1) BRPI0616901A2 (da)
CA (1) CA2627673A1 (da)
DK (1) DK1943243T3 (da)
DO (1) DOP2006000234A (da)
EA (1) EA015189B1 (da)
PE (1) PE20070795A1 (da)
PL (1) PL1943243T3 (da)
PT (1) PT1943243E (da)
RS (1) RS51949B (da)
SI (1) SI1943243T1 (da)
TN (1) TNSN08191A1 (da)
TW (1) TWI325423B (da)
WO (1) WO2007053394A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0905955D0 (en) 2009-04-06 2009-05-20 Respivert Ltd Novel compounds
JP5787977B2 (ja) 2010-04-08 2015-09-30 レスピバート・リミテツド Ｐ３８ｍａｐキナーゼ阻害剤
EP2582700B1 (en) 2010-06-17 2016-11-02 Respivert Limited Respiratory formulations containing p38 mapk inhibitors
JP2014521617A (ja) 2011-07-26 2014-08-28 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング バニロイド受容体リガンドとしての置換二環性芳香族カルボキサミドおよび尿素誘導体
WO2014033449A1 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
US20150225373A1 (en) 2012-08-29 2015-08-13 Respivert Limited Kinase inhibitors
EP2890460B1 (en) 2012-08-29 2017-02-22 Respivert Limited Kinase inhibitors
EP2925742B1 (en) 2012-11-16 2016-10-26 Respivert Limited Kinase inhibitors
WO2014162121A1 (en) 2013-04-02 2014-10-09 Topivert Pharma Limited Kinase inhibitors based upon n-alkyl pyrazoles
EP2981535B8 (en) 2013-04-02 2021-03-10 Oxular Acquisitions Limited Urea derivatives useful as kinase inhibitors
EP3083604A1 (en) 2013-12-20 2016-10-26 Respivert Limited Urea derivatives useful as kinase inhibitors
DK3113772T3 (da) 2014-03-07 2020-12-07 Biocryst Pharm Inc Trifluormethylsubstituerede pyrazoler som inhibitorer af kallikrein fra humant plasma
MA40774A (fr) 2014-10-01 2017-08-08 Respivert Ltd Dérivés de diaryle-urée en tant qu'inhibiteurs de kinase p38
BR112018067552A2 (pt) 2016-04-06 2019-01-08 Topivert Pharma Ltd inibidores de cinase
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
PT3691620T (pt) 2017-10-05 2022-10-06 Fulcrum Therapeutics Inc Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd
LT3786160T (lt) 2017-10-27 2022-09-26 Boehringer Ingelheim International Gmbh Piridino dariniai ir jų terapinis panaudojimas kaip trpc6 inhibitorių
BR112022026698A2 (pt) 2020-08-13 2023-02-23 Boehringer Ingelheim Int Tratamento da deficiência cognitiva associada à esquizofrenia
CN117567449A (zh) 2020-10-13 2024-02-20 勃林格殷格翰国际有限公司 再加工方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836563T2 (de) * 1997-12-22 2007-05-16 Bayer Pharmaceuticals Corp., West Haven INHIBIERUNG DER p38 KINASE-AKTIVITÄT DURCH DIE VERWENDUNG VON ARYL- UND HETEROARYL-SUBSTITUIERTEN HARNSTOFFEN
WO2006009741A1 (en) * 2004-06-23 2006-01-26 Eli Lilly And Company Kinase inhibitors

Also Published As

Publication number Publication date
EA200801199A1 (ru) 2008-08-29
AR056582A1 (es) 2007-10-10
US20080269244A1 (en) 2008-10-30
EP1943243B1 (en) 2010-12-29
DOP2006000234A (es) 2007-05-31
KR101004156B1 (ko) 2010-12-27
AU2006309044A1 (en) 2007-05-10
PE20070795A1 (es) 2007-08-24
ATE493403T1 (de) 2011-01-15
WO2007053394A1 (en) 2007-05-10
PT1943243E (pt) 2011-01-11
EP1943243A1 (en) 2008-07-16
AU2006309044B2 (en) 2011-10-13
CA2627673A1 (en) 2007-05-10
TWI325423B (en) 2010-06-01
TW200800184A (en) 2008-01-01
PL1943243T3 (pl) 2011-05-31
US7652015B2 (en) 2010-01-26
BRPI0616901A2 (pt) 2011-07-05
EA015189B1 (ru) 2011-06-30
TNSN08191A1 (en) 2009-10-30
KR20080053394A (ko) 2008-06-12
RS51949B (sr) 2012-02-29
SI1943243T1 (sl) 2011-04-29

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