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ATE311390T1 - Antiparasitäre marcfortine und paraherquamide - Google Patents

Antiparasitäre marcfortine und paraherquamide

Info

Publication number
ATE311390T1
ATE311390T1 AT96922529T AT96922529T ATE311390T1 AT E311390 T1 ATE311390 T1 AT E311390T1 AT 96922529 T AT96922529 T AT 96922529T AT 96922529 T AT96922529 T AT 96922529T AT E311390 T1 ATE311390 T1 AT E311390T1
Authority
AT
Austria
Prior art keywords
paraherquamid
marcfortine
antiparasitic
antiparasitic marcfortine
Prior art date
Application number
AT96922529T
Other languages
English (en)
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE311390(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of ATE311390T1 publication Critical patent/ATE311390T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT96922529T 1995-07-21 1996-06-26 Antiparasitäre marcfortine und paraherquamide ATE311390T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21
PCT/US1996/010686 WO1997003988A1 (en) 1995-07-21 1996-06-26 Antiparasitic marcfortines and paraherquamides

Publications (1)

Publication Number Publication Date
ATE311390T1 true ATE311390T1 (de) 2005-12-15

Family

ID=21695455

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96922529T ATE311390T1 (de) 1995-07-21 1996-06-26 Antiparasitäre marcfortine und paraherquamide

Country Status (30)

Country Link
US (2) US5703078A (de)
EP (3) EP0871631B1 (de)
JP (2) JP4122447B2 (de)
KR (1) KR100428335B1 (de)
CN (2) CN1125824C (de)
AR (10) AR003466A1 (de)
AT (1) ATE311390T1 (de)
AU (1) AU699644B2 (de)
BR (7) BR9612972B8 (de)
CA (1) CA2225813C (de)
CO (1) CO4750664A1 (de)
CZ (1) CZ296008B6 (de)
DE (1) DE69635524T2 (de)
DK (2) DK0871631T3 (de)
ES (2) ES2249783T3 (de)
FI (2) FI115912B (de)
HU (1) HU226296B1 (de)
ID (1) ID30373A (de)
MX (1) MX9800625A (de)
MY (1) MY113806A (de)
NO (1) NO324287B1 (de)
NZ (1) NZ311952A (de)
PL (1) PL185007B1 (de)
PT (1) PT1489082E (de)
RU (1) RU2162090C2 (de)
SI (1) SI0871631T1 (de)
SK (2) SK285248B6 (de)
TW (1) TW334436B (de)
WO (1) WO1997003988A1 (de)
ZA (1) ZA965908B (de)

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AU4911097A (en) * 1996-11-15 1998-06-03 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
SI3050874T1 (sl) 2008-11-14 2019-04-30 Merial Inc. Enantiomerno obogatene ariloazol-2-il cianoetilamino paraziticidne spojine
CN102271672B (zh) 2008-11-19 2015-02-04 梅里亚有限公司 用于治疗寄生物感染的包含单独的或与甲脒组合的1-芳基吡唑的组合物
CA2745434C (en) 2008-12-04 2017-06-20 Merial Limited Dimeric avermectin and milbemycin derivatives
EP2314292A1 (de) 2009-10-20 2011-04-27 Novartis AG Endoparasitisch wirkende Zusammensetzungen
NZ600252A (en) 2009-12-04 2014-03-28 Merial Ltd Pesticidal bis-organosulfur compounds
NZ600922A (en) 2009-12-17 2013-10-25 Merial Ltd Anti parasitic dihydroazole compounds and compositions comprising same
CA2784141C (en) 2009-12-17 2017-10-24 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
US8822528B2 (en) 2010-11-16 2014-09-02 Merial Limited Monensin derivatives for the treatment and prevention of protozoal infections
CA2840396C (en) 2011-06-27 2020-07-14 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
PT2755473T (pt) 2011-09-12 2019-03-25 Boehringer Ingelheim Animal Health Usa Inc Composições parasiticidas compreendendo um agente ativo de isoxazolina, métodos e suas utilizações
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
DK3351546T5 (da) 2011-12-02 2024-08-12 Boehringer Ingelheim Vetmedica Gmbh Langtidsvirkende injicerbare moxidectinformuleringer
PL232463B1 (pl) 2012-02-06 2019-06-28 Merial Inc Miękka, nadająca się do żucia kompozycja weterynaryjna do leczenia i/lub zapobiegania infekcji lub inwazji pasożytniczej u zwierzęcia oraz jej zastosowanie
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
MX351636B (es) 2012-04-20 2017-10-23 Merial Ltd Composiciones parasiticidas que comprenden derivados de benzimidazol, métodos y usos de los mismos.
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
NZ708350A (en) 2012-11-20 2016-08-26 Merial Inc Anthelmintic compounds and compositions and method of using thereof
EP3063144B1 (de) 2013-11-01 2021-09-08 Boehringer Ingelheim Animal Health USA Inc. Antiparasitäre und pestizide isoxazolinverbindungen
CA2945766C (en) 2014-04-17 2023-09-26 Merial, Inc. Use of malononitrile compounds for protecting animals from parasites
AR100530A1 (es) 2014-05-19 2016-10-12 Merial Inc Compuestos antihelmínticos
BR122020023385B1 (pt) 2014-06-19 2021-05-25 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
WO2019036407A1 (en) 2017-08-14 2019-02-21 Merial, Inc. PYRAZOLE-ISOXAZOLINE COMPOUNDS WITH PESTICIDE AND PARASITICIDE ACTIVITY
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
PE20211275A1 (es) 2018-07-09 2021-07-19 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos
EP3883648A1 (de) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylaminoverbindung, zusammensetzungen davon, verfahren zur herstellung und verfahren zur verwendung davon
JP2022522200A (ja) 2019-03-01 2022-04-14 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 注射用クロルスロン組成物、その方法および使用
KR20220002890A (ko) 2019-03-19 2022-01-07 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
JP2024504208A (ja) 2020-12-21 2024-01-30 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー イソオキサゾリン化合物を含む殺寄生虫首輪
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof

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US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
IE904606A1 (en) * 1989-12-21 1991-07-03 Beecham Group Plc Novel products
GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
WO1992022555A1 (en) * 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
AR038429A2 (es) 2005-01-12
US5703078A (en) 1997-12-30
DE69635524T2 (de) 2006-07-06
CZ11098A3 (cs) 1998-06-17
CA2225813A1 (en) 1997-02-06
AR038427A2 (es) 2005-01-12
AR038431A2 (es) 2005-01-12
CN1191537A (zh) 1998-08-26
BR9612973B8 (pt) 2014-10-29
FI20050238L (fi) 2005-03-04
NO980255L (no) 1998-03-20
FI980112A0 (fi) 1998-01-20
NO324287B1 (no) 2007-09-17
PL324574A1 (en) 1998-06-08
EP1400523A2 (de) 2004-03-24
CN1277830C (zh) 2006-10-04
KR100428335B1 (ko) 2004-06-16
AU699644B2 (en) 1998-12-10
SK285248B6 (sk) 2006-09-07
CA2225813C (en) 2008-02-26
FI980112L (fi) 1998-01-20
JP4122447B2 (ja) 2008-07-23
HU226296B1 (hu) 2008-08-28
AR038430A2 (es) 2005-01-12
DK0871631T3 (da) 2006-03-13
HUP9802221A2 (hu) 1999-02-01
EP0871631A1 (de) 1998-10-21
DE69635524D1 (de) 2006-01-05
ES2439569T3 (es) 2014-01-23
AR052907A1 (es) 2007-04-11
JP2008007516A (ja) 2008-01-17
BR9609812B8 (pt) 2014-10-29
SK284833B6 (sk) 2005-12-01
EP1400523A3 (de) 2004-04-07
FI118471B (fi) 2007-11-30
HK1061242A1 (en) 2004-09-10
BR9612975B8 (pt) 2014-10-29
ZA965908B (en) 1997-01-12
AR038434A2 (es) 2005-01-12
BR9609812A (pt) 1999-03-02
ID30373A (id) 1997-01-23
FI115912B (fi) 2005-08-15
DK1489082T3 (da) 2013-12-09
AR038433A2 (es) 2005-01-12
HK1017883A1 (en) 1999-12-03
JPH11509550A (ja) 1999-08-24
CZ296008B6 (cs) 2005-12-14
MY113806A (en) 2002-05-31
US5750695A (en) 1998-05-12
SI0871631T1 (sl) 2006-04-30
HUP9802221A3 (en) 2000-05-29
EP1489082B1 (de) 2013-11-20
CO4750664A1 (es) 1999-03-31
NZ311952A (en) 1999-03-29
PL185007B1 (pl) 2003-01-31
RU2162090C2 (ru) 2001-01-20
AR038432A2 (es) 2005-01-12
PT1489082E (pt) 2013-12-23
TW334436B (en) 1998-06-21
BR9612972B8 (pt) 2014-10-29
NO980255D0 (no) 1998-01-20
CN1495183A (zh) 2004-05-12
BR9612944B8 (pt) 2014-10-29
WO1997003988A1 (en) 1997-02-06
BR9612974B8 (pt) 2014-10-29
CN1125824C (zh) 2003-10-29
AR038428A2 (es) 2005-01-12
EP1489082A1 (de) 2004-12-22
MX9800625A (es) 1998-04-30
ES2249783T3 (es) 2006-04-01
AR003466A1 (es) 1998-08-05
SK5498A3 (en) 1998-08-05
EP0871631B1 (de) 2005-11-30
AU6337396A (en) 1997-02-18
BR9612963B8 (pt) 2014-10-29

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