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FI20050238L - Markfortiini- ja paraherkvamidiyhdisteet - Google Patents

Markfortiini- ja paraherkvamidiyhdisteet Download PDF

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Publication number
FI20050238L
FI20050238L FI20050238A FI20050238A FI20050238L FI 20050238 L FI20050238 L FI 20050238L FI 20050238 A FI20050238 A FI 20050238A FI 20050238 A FI20050238 A FI 20050238A FI 20050238 L FI20050238 L FI 20050238L
Authority
FI
Finland
Prior art keywords
marcfortine
paraherquamide compounds
paraherquamide
compounds
Prior art date
Application number
FI20050238A
Other languages
English (en)
Swedish (sv)
Other versions
FI118471B (fi
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI20050238(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI20050238L publication Critical patent/FI20050238L/fi
Application granted granted Critical
Publication of FI118471B publication Critical patent/FI118471B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epoxy Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)
FI20050238A 1995-07-21 2005-03-04 Markfortiini- ja paraherkvamidiyhdisteet FI118471B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21
US132495 1995-07-21
US9610686 1996-06-26
PCT/US1996/010686 WO1997003988A1 (en) 1995-07-21 1996-06-26 Antiparasitic marcfortines and paraherquamides

Publications (2)

Publication Number Publication Date
FI20050238L true FI20050238L (fi) 2005-03-04
FI118471B FI118471B (fi) 2007-11-30

Family

ID=21695455

Family Applications (2)

Application Number Title Priority Date Filing Date
FI980112A FI115912B (fi) 1995-07-21 1998-01-20 Antiparasiittiset markfortiini- ja paraherkvamidijohdannaiset
FI20050238A FI118471B (fi) 1995-07-21 2005-03-04 Markfortiini- ja paraherkvamidiyhdisteet

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI980112A FI115912B (fi) 1995-07-21 1998-01-20 Antiparasiittiset markfortiini- ja paraherkvamidijohdannaiset

Country Status (30)

Country Link
US (2) US5703078A (fi)
EP (3) EP0871631B1 (fi)
JP (2) JP4122447B2 (fi)
KR (1) KR100428335B1 (fi)
CN (2) CN1125824C (fi)
AR (10) AR003466A1 (fi)
AT (1) ATE311390T1 (fi)
AU (1) AU699644B2 (fi)
BR (7) BR9612944B8 (fi)
CA (1) CA2225813C (fi)
CO (1) CO4750664A1 (fi)
CZ (1) CZ296008B6 (fi)
DE (1) DE69635524T2 (fi)
DK (2) DK1489082T3 (fi)
ES (2) ES2439569T3 (fi)
FI (2) FI115912B (fi)
HU (1) HU226296B1 (fi)
ID (1) ID30373A (fi)
MX (1) MX9800625A (fi)
MY (1) MY113806A (fi)
NO (1) NO324287B1 (fi)
NZ (1) NZ311952A (fi)
PL (1) PL185007B1 (fi)
PT (1) PT1489082E (fi)
RU (1) RU2162090C2 (fi)
SI (1) SI0871631T1 (fi)
SK (2) SK285248B6 (fi)
TW (1) TW334436B (fi)
WO (1) WO1997003988A1 (fi)
ZA (1) ZA965908B (fi)

Families Citing this family (44)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
WO1998021211A1 (en) * 1996-11-15 1998-05-22 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
AR074024A1 (es) 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
KR101660068B1 (ko) 2008-11-19 2016-09-26 메리얼 인코포레이티드 기생충 감염 치료를 위한 1-아릴피라졸 단독 또는 포름아미딘과의 조합을 포함하는 조성물
TWI457347B (zh) 2008-12-04 2014-10-21 Merial Ltd 二聚合的阿佛菌素(avermectin)及密倍脈心(milbemycin)衍生物
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
CN102712583B (zh) 2009-12-04 2015-04-08 梅里亚有限公司 农药用双-有机硫化合物
RS58691B1 (sr) 2009-12-17 2019-06-28 Merial Inc Antiparazitske kompozicije dihidroazola
WO2011075592A1 (en) 2009-12-17 2011-06-23 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
MX2013005414A (es) 2010-11-16 2013-08-29 Centre Nat Rech Scient Derivados de monensina novedosos para el tratamiento y prevencion de infecciones por protozoarios.
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
BR112013033568B1 (pt) 2011-06-27 2020-11-24 Merial, Inc Compostos eter amidopiridil e composiqoes, e seu uso contra parasitas
PH12018501647A1 (en) 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
PL2785719T3 (pl) 2011-12-02 2018-03-30 Merial, Inc. Długodziałające wstrzykiwalne postaci moksydektyny i nowe postaci krystaliczne moksydektyny
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014026184B1 (pt) 2012-04-20 2019-04-24 Merial, Inc. Composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
US20220202835A1 (en) 2019-03-01 2022-06-30 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
IE904606A1 (en) * 1989-12-21 1991-07-03 Beecham Group Plc Novel products
GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
WO1992022555A1 (en) * 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
AR038430A2 (es) 2005-01-12
ID30373A (id) 1997-01-23
AR038433A2 (es) 2005-01-12
US5703078A (en) 1997-12-30
EP1400523A2 (en) 2004-03-24
AR038429A2 (es) 2005-01-12
NZ311952A (en) 1999-03-29
BR9612944B8 (pt) 2014-10-29
AU6337396A (en) 1997-02-18
JP4122447B2 (ja) 2008-07-23
US5750695A (en) 1998-05-12
AR038432A2 (es) 2005-01-12
EP1489082A1 (en) 2004-12-22
MX9800625A (es) 1998-04-30
BR9609812B8 (pt) 2014-10-29
BR9612974B8 (pt) 2014-10-29
CZ11098A3 (cs) 1998-06-17
HK1017883A1 (en) 1999-12-03
CN1125824C (zh) 2003-10-29
FI118471B (fi) 2007-11-30
CZ296008B6 (cs) 2005-12-14
RU2162090C2 (ru) 2001-01-20
AR038427A2 (es) 2005-01-12
HK1061242A1 (en) 2004-09-10
AR003466A1 (es) 1998-08-05
HU226296B1 (hu) 2008-08-28
CA2225813C (en) 2008-02-26
ES2439569T3 (es) 2014-01-23
NO980255D0 (no) 1998-01-20
WO1997003988A1 (en) 1997-02-06
ES2249783T3 (es) 2006-04-01
HUP9802221A2 (hu) 1999-02-01
AR052907A1 (es) 2007-04-11
DK0871631T3 (da) 2006-03-13
EP0871631A1 (en) 1998-10-21
CN1191537A (zh) 1998-08-26
SI0871631T1 (sl) 2006-04-30
AR038431A2 (es) 2005-01-12
EP1400523A3 (en) 2004-04-07
CA2225813A1 (en) 1997-02-06
DE69635524D1 (de) 2006-01-05
AU699644B2 (en) 1998-12-10
FI980112A0 (fi) 1998-01-20
AR038428A2 (es) 2005-01-12
PL185007B1 (pl) 2003-01-31
BR9612972B8 (pt) 2014-10-29
SK5498A3 (en) 1998-08-05
PL324574A1 (en) 1998-06-08
DK1489082T3 (da) 2013-12-09
PT1489082E (pt) 2013-12-23
JP2008007516A (ja) 2008-01-17
EP0871631B1 (en) 2005-11-30
CO4750664A1 (es) 1999-03-31
CN1277830C (zh) 2006-10-04
FI980112L (fi) 1998-01-20
FI115912B (fi) 2005-08-15
JPH11509550A (ja) 1999-08-24
DE69635524T2 (de) 2006-07-06
NO980255L (no) 1998-03-20
BR9612975B8 (pt) 2014-10-29
ATE311390T1 (de) 2005-12-15
KR100428335B1 (ko) 2004-06-16
TW334436B (en) 1998-06-21
BR9612973B8 (pt) 2014-10-29
CN1495183A (zh) 2004-05-12
BR9609812A (pt) 1999-03-02
ZA965908B (en) 1997-01-12
SK285248B6 (sk) 2006-09-07
MY113806A (en) 2002-05-31
SK284833B6 (sk) 2005-12-01
NO324287B1 (no) 2007-09-17
BR9612963B8 (pt) 2014-10-29
EP1489082B1 (en) 2013-11-20
AR038434A2 (es) 2005-01-12
HUP9802221A3 (en) 2000-05-29

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