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AR059302A1 - Sales de adicion de acido de n-[ 3- [4- (2- metoxifenil) -1-piperazinil] -propil] -7-oxo-5-trifluormetil-7h-tieno [3,2-b] piran-3-carboxamida - Google Patents

Sales de adicion de acido de n-[ 3- [4- (2- metoxifenil) -1-piperazinil] -propil] -7-oxo-5-trifluormetil-7h-tieno [3,2-b] piran-3-carboxamida

Info

Publication number
AR059302A1
AR059302A1 ARP070100452A ARP070100452A AR059302A1 AR 059302 A1 AR059302 A1 AR 059302A1 AR P070100452 A ARP070100452 A AR P070100452A AR P070100452 A ARP070100452 A AR P070100452A AR 059302 A1 AR059302 A1 AR 059302A1
Authority
AR
Argentina
Prior art keywords
salts
carboxamide
oxo
addition salts
trifluormetil
Prior art date
Application number
ARP070100452A
Other languages
English (en)
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of AR059302A1 publication Critical patent/AR059302A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se provee sales de adicion de N-{3-[4-(2-metoxifenil)-1-piperazinil]propil}-7-oxo-5-trifluormetil-7H-tieno[3,2-b]piran-3-carboxamida con ácidos inorgánicos, sulfonicos o carboxílicos. Las sales preferidas son aquellas formadas con ácidos clorhídrico, bromhídrico, metansulfonjco, bencensulfonico, toluensulfonico o naftalen-1,5-disulfonico. Es aun más preferida una sal mesilato cristalina en una forma polimorfica unica. Las sales son con preferencia al menos 95% puras, conteniendo las impurezas no más de 2% en peso del total del subproducto N-{3-[4-(2-metoxifenil)-1-piperazinil]-propil}-4-hidroxi-5-[(Z)-4,4,4-trifluor-3-hidroxi-2-butenoil]-tiofen-3-carboxamida. También se proveen composiciones farmacéuticas que contienen las sales de la presente. Las sales y las composiciones farmacéuticas que las contienen son utiles para el tratamiento de síndromes obstructivos del tracto urinario inferior, que incluyen HPB.
ARP070100452A 2006-02-03 2007-02-02 Sales de adicion de acido de n-[ 3- [4- (2- metoxifenil) -1-piperazinil] -propil] -7-oxo-5-trifluormetil-7h-tieno [3,2-b] piran-3-carboxamida AR059302A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76482406P 2006-02-03 2006-02-03

Publications (1)

Publication Number Publication Date
AR059302A1 true AR059302A1 (es) 2008-03-26

Family

ID=37983328

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070100452A AR059302A1 (es) 2006-02-03 2007-02-02 Sales de adicion de acido de n-[ 3- [4- (2- metoxifenil) -1-piperazinil] -propil] -7-oxo-5-trifluormetil-7h-tieno [3,2-b] piran-3-carboxamida

Country Status (6)

Country Link
US (1) US20070185129A1 (es)
AR (1) AR059302A1 (es)
PE (1) PE20070950A1 (es)
TW (1) TW200804395A (es)
UY (1) UY30111A1 (es)
WO (1) WO2007088063A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557807B2 (en) * 2008-01-24 2013-10-15 Signal Rx Pharmaceuticals, Inc. Thienopyranones as kinase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1313581B1 (it) * 1999-07-30 2002-09-09 Recordati Chem Pharm Derivati tienopirancarbossamidici.
US6387909B1 (en) * 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
US6306861B1 (en) * 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
TWI265925B (en) * 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
ITMI20010164A1 (it) * 2001-01-30 2002-07-30 Recordati Chem Pharm Alfa 1 antagonisti selettivi a + d
US6992192B2 (en) * 2001-06-05 2006-01-31 Lilly Icos Llc. Carboline derivatives as PDE5 inhibitors

Also Published As

Publication number Publication date
US20070185129A1 (en) 2007-08-09
PE20070950A1 (es) 2007-09-10
UY30111A1 (es) 2007-04-30
TW200804395A (en) 2008-01-16
WO2007088063A1 (en) 2007-08-09

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal