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AR002716A1 - Uso farmacologico de ciertos derivados de cistina para la preparacion de un medicamento - Google Patents

Uso farmacologico de ciertos derivados de cistina para la preparacion de un medicamento

Info

Publication number
AR002716A1
AR002716A1 ARP960101738A AR10173896A AR002716A1 AR 002716 A1 AR002716 A1 AR 002716A1 AR P960101738 A ARP960101738 A AR P960101738A AR 10173896 A AR10173896 A AR 10173896A AR 002716 A1 AR002716 A1 AR 002716A1
Authority
AR
Argentina
Prior art keywords
preparation
medicinal product
pharmacological use
moiety
cystine derivatives
Prior art date
Application number
ARP960101738A
Other languages
English (en)
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of AR002716A1 publication Critical patent/AR002716A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

El uso para la preparación de un medicamento para la profilaxis o tratamiento de restenosis, También se da a conocer una preparación farmacéuticaque contiene a dichos derivados. Un compuesto de fórmula (I) donde R es hidrógeno,meti lo, etilo, n-propilo o una porción -COR1 donde R1 es un grupoalquilo de cadena recta o ramificada que tiene 1-12 átomos de carbono, R2 es un grupo alquilo de cadena recta o ramificada que tiene 1-12 átomos de carbono yR3 es una porción queprovee un éster que es hidrolizable en los fluidos del cuerpo para liberar el compuesto activo en forma de ácido libre, o una salfisiológicamente aceptable y/o un isómero estereoquímico.
ARP960101738A 1995-03-14 1996-03-13 Uso farmacologico de ciertos derivados de cistina para la preparacion de un medicamento AR002716A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500897A SE9500897D0 (sv) 1995-03-14 1995-03-14 The pharmacological use of certain cystine derivatives

Publications (1)

Publication Number Publication Date
AR002716A1 true AR002716A1 (es) 1998-04-29

Family

ID=20397536

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960101738A AR002716A1 (es) 1995-03-14 1996-03-13 Uso farmacologico de ciertos derivados de cistina para la preparacion de un medicamento

Country Status (24)

Country Link
US (1) US5883126A (es)
EP (1) EP0814798A1 (es)
JP (1) JPH11501916A (es)
KR (1) KR19980703055A (es)
CN (1) CN1183718A (es)
AR (1) AR002716A1 (es)
AU (1) AU701287B2 (es)
BR (1) BR9607225A (es)
CA (1) CA2214831A1 (es)
CZ (1) CZ288219B6 (es)
EE (1) EE03382B1 (es)
HU (1) HUP9801985A3 (es)
IL (1) IL117465A (es)
IS (1) IS4554A (es)
NO (1) NO974143D0 (es)
NZ (1) NZ303781A (es)
PL (1) PL183234B1 (es)
SE (1) SE9500897D0 (es)
SK (1) SK282448B6 (es)
TR (1) TR199700945T1 (es)
TW (1) TW385249B (es)
UA (1) UA42830C2 (es)
WO (1) WO1996028149A1 (es)
ZA (1) ZA961749B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014306A1 (en) * 1995-10-17 1997-04-24 Dovetail Technologies, Inc. Low molecular weight cell, bone marrow and immune stimulants
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
SE9900438D0 (sv) * 1999-02-10 1999-02-10 Astra Ab The pharmacological use of certian cystine derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR8205M (es) * 1968-12-20 1970-09-14
US3878305A (en) * 1972-05-25 1975-04-15 Procter & Gamble Fortification of foodstuffs with n-acyl derivatives of sulphur-containing l-amino acids
FR2289179A1 (fr) * 1974-10-28 1976-05-28 Morelle Jean Sels metalliques de lipoaminoacides
US3952115A (en) * 1975-04-02 1976-04-20 The Procter & Gamble Company Fortification of foodstuffs with N-acyl derivatives of sulfur-containing L-amino acid esters
GB2097256B (en) * 1981-04-02 1985-05-30 Morelle Jean V Compositions containing n-butyryl alphaaminoacids
FR2503151A1 (fr) * 1981-04-02 1982-10-08 Morelle Jean Butyryminoacides soufres. mode de preparation. emploi comme element keratogenique chez l'homme et l'animal et comme agent de fertilisation chez les vegetaux
US4724239A (en) * 1985-09-16 1988-02-09 Morgan Lee R Method of treating chemical ulcers with N,N'-diacetylcystine, N-acetyl homocysteine and N-acetyl cysteine
US4708965A (en) * 1985-09-16 1987-11-24 Morgan Lee R Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives
US4827016A (en) * 1985-09-16 1989-05-02 Morgan Lee R Method and compounds for reducing dermal inflammations
JPS62195356A (ja) * 1986-02-20 1987-08-28 Seiwa Kasei:Kk シスチン誘導体及びその塩
IL98310A (en) * 1990-06-08 1996-08-04 Astra Ab Pharmaceutical compositions comprising cystine derivatives
TW221376B (es) * 1990-06-28 1994-03-01 Astra Ab
IT1249650B (it) * 1991-05-29 1995-03-09 Poli Ind Chimica Spa N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico
SE9103572D0 (sv) * 1991-11-29 1991-11-29 Astra Ab Organic salts of n,n'-diacetyl cystine
EP0746202A4 (en) * 1992-01-06 1997-06-25 Health Maintenance Programs COMPOSITION CONTAINING A PHARMACEUTICALLY ACTIVE ANTI-OXIDANT AND METHOD FOR USE IN THE PREVENTION AND TREATMENT OF RESTENOSIS AFTER ANGIOPLASTY
DE4224670A1 (de) * 1992-07-25 1994-01-27 Boehringer Mannheim Gmbh Verwendung von â,w-Dicarbonsäuren als Fibrinogensenker

Also Published As

Publication number Publication date
EE9700229A (et) 1998-04-15
PL322328A1 (en) 1998-01-19
US5883126A (en) 1999-03-16
IL117465A0 (en) 1996-07-23
SK282448B6 (sk) 2002-02-05
ZA961749B (en) 1996-09-16
NZ303781A (en) 2001-03-30
AU5018596A (en) 1996-10-02
PL183234B1 (pl) 2002-06-28
KR19980703055A (ko) 1998-09-05
CZ280497A3 (cs) 1998-01-14
WO1996028149A1 (en) 1996-09-19
JPH11501916A (ja) 1999-02-16
IL117465A (en) 2000-07-26
SK120797A3 (en) 1998-02-04
TW385249B (en) 2000-03-21
CZ288219B6 (en) 2001-05-16
NO974143L (no) 1997-09-09
AU701287B2 (en) 1999-01-21
NO974143D0 (no) 1997-09-09
HUP9801985A3 (en) 2000-07-28
MX9706825A (es) 1997-11-29
EE03382B1 (et) 2001-04-16
BR9607225A (pt) 1998-07-07
TR199700945T1 (xx) 1998-02-21
IS4554A (is) 1997-08-27
EP0814798A1 (en) 1998-01-07
CA2214831A1 (en) 1996-09-19
CN1183718A (zh) 1998-06-03
UA42830C2 (uk) 2001-11-15
SE9500897D0 (sv) 1995-03-14
HUP9801985A2 (hu) 1998-12-28

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