OA12756A - 3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. - Google Patents

3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. Download PDF

Info

Publication number: OA12756A
Authority: OA; OAPI
Prior art keywords: préparation; hydrogen; compound according; nmr; 400mhz
Prior art date: 2002-01-22

Application number

OA1200400190A

Other languages

English (en)

Inventor

Charlotte Moira Norfo Allerton

David John Bull

Mark Edward Bunnage

Robert John Maguire

John Steele

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-22

Filing date

2003-01-10

Publication date

2006-07-03

2002-01-22 Priority claimed from GB0201389A external-priority patent/GB0201389D0/en

2002-01-29 Priority claimed from GB0202027A external-priority patent/GB0202027D0/en

2003-01-10 Application filed by Pfizer filed Critical Pfizer

2006-07-03 Publication of OA12756A publication Critical patent/OA12756A/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

OA1200400190A 2002-01-22 2003-01-10 3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. OA12756A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0201389A GB0201389D0 (en)	2002-01-22	2002-01-22	3-(imidazolyl)-2-alkoxypropanoic acids
GB0202027A GB0202027D0 (en)	2002-01-29	2002-01-29	3-(imidazolyl)-2-alkoxypropanoic acids

Publications (1)

Publication Number	Publication Date
OA12756A true OA12756A (en)	2006-07-03

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ID=27614792

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200400190A OA12756A (en)	2002-01-22	2003-01-10	3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors.

Country Status (24)

Country	Link
EP (1)	EP1467731A1 (fr)
JP (1)	JP2005520811A (fr)
KR (1)	KR20040077775A (fr)
CN (1)	CN1620291A (fr)
AP (1)	AP2004003084A0 (fr)
AR (1)	AR038197A1 (fr)
BR (1)	BR0307016A (fr)
CA (1)	CA2472238A1 (fr)
EA (1)	EA200400716A1 (fr)
EC (1)	ECSP045200A (fr)
HR (1)	HRP20040659A2 (fr)
IL (1)	IL162677A0 (fr)
IS (1)	IS7310A (fr)
MA (1)	MA27167A1 (fr)
MX (1)	MXPA04006573A (fr)
NO (1)	NO20043457L (fr)
OA (1)	OA12756A (fr)
PA (1)	PA8563501A1 (fr)
PE (1)	PE20030929A1 (fr)
PL (1)	PL371487A1 (fr)
TN (1)	TNSN04121A1 (fr)
TW (1)	TW200302094A (fr)
UY (1)	UY27615A1 (fr)
WO (1)	WO2003061652A1 (fr)

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WO2005051384A1 (fr) *	2003-11-25	2005-06-09	Pfizer Limited	Compositions pharmaceutiques stabilisees
CA2604912A1 (fr) *	2005-04-18	2006-10-26	Bayer Schering Pharma Aktiengesellschaft	Utilisation d'inhibiteurs de tafi pour ameliorer la reperfusion myocardique et faciliter la pci
NZ592764A (en)	2008-10-29	2012-08-31	Taisho Pharmaceutical Co Ltd	Compound having tafia inhibitory activity
US8987242B2 (en)	2008-12-05	2015-03-24	Merck Sharp & Dohme Corp.	Morpholinone compounds as factor IXA inhibitors
AU2009322342A1 (en) *	2008-12-05	2011-06-30	Merck Sharp & Dohme Corp.	Morpholinone compounds as factor IXa inhibitors
EP2548872B1 (fr) *	2010-03-18	2016-09-28	Daiichi Sankyo Company, Limited	Dérivé d'acide cyclopropanecarboxylique
LT2548871T (lt)	2010-03-18	2017-09-25	Daiichi Sankyo Company, Limited	Cikloalkilpakeistieji imidazolo dariniai
SG11201509144YA (en)	2013-06-10	2015-12-30	Sanofi Sa	MACROCYCLIC UREA DERIVATIVES AS INHIBITORS OF TAFI<sb>A</sb>, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
US20190117624A1 (en)	2016-03-29	2019-04-25	Daiichi Sankyo Company, Limited	Therapeutic agent for inflammatory bowel diseases
EP3682881A4 (fr)	2017-09-14	2021-08-11	Daiichi Sankyo Company, Limited	Composé à structure cyclique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9901572D0 (sv) *	1999-05-03	1999-05-03	Astra Ab	New compounds
ES2334101T3 (es) *	2000-08-17	2010-03-05	Pfizer Limited	Imidazoles sustituidos como inhibidores de tafia.

2003
- 2003-01-10 IL IL16267703A patent/IL162677A0/xx unknown
- 2003-01-10 MX MXPA04006573A patent/MXPA04006573A/es unknown
- 2003-01-10 JP JP2003561596A patent/JP2005520811A/ja active Pending
- 2003-01-10 EP EP03700059A patent/EP1467731A1/fr not_active Withdrawn
- 2003-01-10 PL PL03371487A patent/PL371487A1/xx unknown
- 2003-01-10 CA CA002472238A patent/CA2472238A1/fr not_active Abandoned
- 2003-01-10 WO PCT/IB2003/000060 patent/WO2003061652A1/fr not_active Ceased
- 2003-01-10 EA EA200400716A patent/EA200400716A1/ru unknown
- 2003-01-10 KR KR10-2004-7011370A patent/KR20040077775A/ko not_active Ceased
- 2003-01-10 AP APAP/P/2004/003084A patent/AP2004003084A0/en unknown
- 2003-01-10 CN CNA03802599XA patent/CN1620291A/zh active Pending
- 2003-01-10 HR HR20040659A patent/HRP20040659A2/hr not_active Application Discontinuation
- 2003-01-10 BR BR0307016-6A patent/BR0307016A/pt not_active IP Right Cessation
- 2003-01-10 OA OA1200400190A patent/OA12756A/en unknown
- 2003-01-16 TW TW092100889A patent/TW200302094A/zh unknown
- 2003-01-17 PE PE2003000058A patent/PE20030929A1/es not_active Application Discontinuation
- 2003-01-20 UY UY27615A patent/UY27615A1/es not_active Application Discontinuation
- 2003-01-21 AR ARP030100165A patent/AR038197A1/es unknown
- 2003-01-22 PA PA20038563501A patent/PA8563501A1/es unknown
2004
- 2004-06-14 IS IS7310A patent/IS7310A/is unknown
- 2004-06-30 TN TNP2004000121A patent/TNSN04121A1/en unknown
- 2004-07-15 MA MA27786A patent/MA27167A1/fr unknown
- 2004-07-22 EC EC2004005200A patent/ECSP045200A/es unknown
- 2004-08-19 NO NO20043457A patent/NO20043457L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1467731A1 (fr)	2004-10-20
AR038197A1 (es)	2005-01-05
BR0307016A (pt)	2004-11-03
HRP20040659A2 (en)	2004-10-31
IL162677A0 (en)	2005-11-20
CA2472238A1 (fr)	2003-07-31
TNSN04121A1 (en)	2006-06-01
JP2005520811A (ja)	2005-07-14
KR20040077775A (ko)	2004-09-06
ECSP045200A (es)	2004-08-27
NO20043457L (no)	2004-08-19
MXPA04006573A (es)	2004-10-04
PA8563501A1 (es)	2004-08-31
IS7310A (is)	2004-06-14
MA27167A1 (fr)	2005-01-03
AP2004003084A0 (en)	2004-09-30
CN1620291A (zh)	2005-05-25
PE20030929A1 (es)	2003-11-05
UY27615A1 (es)	2003-08-29
WO2003061652A1 (fr)	2003-07-31
PL371487A1 (en)	2005-06-13
WO2003061652A8 (fr)	2004-09-10
TW200302094A (en)	2003-08-01
EA200400716A1 (ru)	2004-12-30

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