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NZ257470A - 5-hydrazino-quinolone derivatives and antimicrobial medicaments - Google Patents

5-hydrazino-quinolone derivatives and antimicrobial medicaments

Info

Publication number
NZ257470A
NZ257470A NZ257470A NZ25747093A NZ257470A NZ 257470 A NZ257470 A NZ 257470A NZ 257470 A NZ257470 A NZ 257470A NZ 25747093 A NZ25747093 A NZ 25747093A NZ 257470 A NZ257470 A NZ 257470A
Authority
NZ
New Zealand
Prior art keywords
hydrazino
quinolone derivatives
antimicrobial medicaments
medicaments
antimicrobial
Prior art date
Application number
NZ257470A
Other languages
English (en)
Inventor
Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NZ257470A publication Critical patent/NZ257470A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
NZ257470A 1992-10-30 1993-10-22 5-hydrazino-quinolone derivatives and antimicrobial medicaments NZ257470A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30

Publications (1)

Publication Number Publication Date
NZ257470A true NZ257470A (en) 1997-08-22

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ257470A NZ257470A (en) 1992-10-30 1993-10-22 5-hydrazino-quinolone derivatives and antimicrobial medicaments

Country Status (21)

Country Link
EP (1) EP0666853A1 (xx)
JP (1) JPH08502750A (xx)
KR (1) KR950704301A (xx)
CN (1) CN1064357C (xx)
AU (1) AU687018B2 (xx)
BR (1) BR9307347A (xx)
CA (1) CA2148003A1 (xx)
CZ (1) CZ282581B6 (xx)
EG (1) EG20543A (xx)
FI (1) FI952049A7 (xx)
HU (1) HUT72072A (xx)
IL (1) IL107323A (xx)
MX (1) MX9306814A (xx)
NO (1) NO951640L (xx)
NZ (1) NZ257470A (xx)
PL (1) PL178094B1 (xx)
RU (1) RU2126000C1 (xx)
SG (1) SG59979A1 (xx)
SK (1) SK54795A3 (xx)
WO (1) WO1994010163A1 (xx)
ZA (1) ZA938089B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
BR9508514A (pt) * 1994-08-02 1997-12-23 Procter & Gamble Processo para fabricação de compostos antimicrobiais
EP0775145A1 (en) * 1994-08-02 1997-05-28 The Procter & Gamble Company Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
DK0882725T3 (da) * 1996-02-09 2003-01-13 Toyama Chemical Co Ltd Quinoloncarboxylsyrederivater eller deres salte
RU2248199C1 (ru) * 2003-06-02 2005-03-20 Открытое Акционерное Общество "Акционерное Курганское общество медицинских препаратов и изделий "Синтез" (ОАО "Синтез") Глазные капли и способ их получения
RU2265437C2 (ru) * 2003-07-02 2005-12-10 Суханов Александр Владимирович Способ лечения заболеваний желудка и двенадцатиперстной кишки, вызванных helicobacter pylori
RU2245134C1 (ru) * 2003-09-02 2005-01-27 Открытое акционерное общество "Красфарма" Состав офлоксацина для инъекций
DK1666477T3 (da) 2003-09-10 2013-07-29 Kyorin Seiyaku Kk 7-(4-trisubstitueret 3-cyclopropylaminomethyl-1- pyrrolidinyl)-quinoloncarboxylsyre-derivat
DK1901749T3 (en) * 2005-05-18 2016-10-24 Raptor Pharmaceuticals Inc Aerosolized fluoroquinolones AND USES THEREOF
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EE05697B1 (et) 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Kinoliini derivaadid kui antibakteriaalsed toimeained
EA010601B1 (ru) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Производные хинолина в качестве антибактериальных агентов
CN101020647B (zh) * 2007-02-14 2011-03-30 杭州师范学院 一种β-环丙胺基丙烯酸(酯)的合成方法
EP2150544B1 (en) * 2007-03-19 2016-01-13 Takeda Pharmaceutical Company Limited Mapk/erk kinase inhibitors
DK3092901T3 (da) * 2007-10-05 2020-05-18 Senhwa Biosciences Inc Quinolonanaloger og fremgangsmåder relateret dertil
TWI441830B (zh) * 2008-06-03 2014-06-21 Actelion Pharmaceuticals Ltd 〔4-(1-胺基-乙基)-環己基〕-甲基胺及〔6-(1-胺基-乙基)-四氫-吡喃-3-基〕-甲基-胺衍生物
US8815838B2 (en) 2008-10-07 2014-08-26 David C. Griffith Aerosol fluoroquinolone formulations for improved pharmacokinetics
CA2739893C (en) 2008-10-07 2016-10-04 Mpex Pharmaceuticals, Inc. Inhalation of levofloxacin for reducing lung inflammation
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
EP3569235A1 (en) 2009-09-04 2019-11-20 Horizon Orphan LLC Use of aerosolized levofloxacin for treating cystic fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
RU2049777C1 (ru) * 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения
JPH05506033A (ja) * 1990-04-18 1993-09-02 ノーウィッチ、イートン、ファーマスーティカルズ、インコーポレーテッド 抗微生物性キノロニルラクタム類
DK0559774T3 (da) * 1990-11-30 2000-01-31 Warner Lambert Co Individuelle stereoisomerer af 7-/3-(1-aminoalkyl)-1-pyrrolidinal/-quinoloner og naphthyridoner som antibakterielle midler

Also Published As

Publication number Publication date
NO951640D0 (no) 1995-04-28
EG20543A (en) 1999-07-31
RU2126000C1 (ru) 1999-02-10
CZ282581B6 (cs) 1997-08-13
CN1064357C (zh) 2001-04-11
ZA938089B (en) 1994-06-07
AU5409794A (en) 1994-05-24
PL308671A1 (en) 1995-08-21
KR950704301A (ko) 1995-11-17
CA2148003A1 (en) 1994-05-11
NO951640L (no) 1995-06-30
PL178094B1 (pl) 2000-02-29
AU687018B2 (en) 1998-02-19
HU9501237D0 (en) 1995-06-28
SG59979A1 (en) 1999-02-22
WO1994010163A1 (en) 1994-05-11
JPH08502750A (ja) 1996-03-26
HUT72072A (en) 1996-03-28
FI952049L (fi) 1995-04-28
EP0666853A1 (en) 1995-08-16
RU95110762A (ru) 1997-01-10
CZ109795A3 (en) 1995-12-13
CN1092773A (zh) 1994-09-28
IL107323A0 (en) 1994-01-25
IL107323A (en) 2000-06-01
MX9306814A (es) 1994-07-29
FI952049A0 (fi) 1995-04-28
SK54795A3 (en) 1995-12-06
BR9307347A (pt) 1999-05-25
FI952049A7 (fi) 1995-04-28

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