NO914710L - Fremgangsmaate for fremstilling av 2beta,19-ethylenbroede steroider som aromataseinhibitorer - Google Patents

Fremgangsmaate for fremstilling av 2beta,19-ethylenbroede steroider som aromataseinhibitorer

Info

Publication number: NO914710L
Authority: NO; Norway
Prior art keywords: aromatase inhibitors; ethylenebroid; 2beta; steroids; procedure
Prior art date: 1990-11-30

Application number

NO91914710A

Other languages

English (en)

Other versions

NO180304C (no

NO180304B (no

NO914710D0 (no

Inventor

John O'neal Johnston

Norton Paul Peet

Joseph Paul Burkhart

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-30

Filing date

1991-11-29

Publication date

1992-06-01

1991-11-29 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1991-11-29 Publication of NO914710D0 publication Critical patent/NO914710D0/no

1992-06-01 Publication of NO914710L publication Critical patent/NO914710L/no

1996-12-16 Publication of NO180304B publication Critical patent/NO180304B/no

1997-04-02 Publication of NO180304C publication Critical patent/NO180304C/no

Links

239000003886 aromatase inhibitor Substances 0.000 title abstract 2
229940046844 aromatase inhibitors Drugs 0.000 title abstract 2
150000003431 steroids Chemical class 0.000 title 1
ORBBRLNBGBWXEF-OQWKOXFXSA-N 3-[(8r,9s,10r,13s,14s)-13-methyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-10-yl]propyl 4-methylbenzenesulfonate Chemical compound C1=CC(C)=CC=C1S(=O)(=O)OCCC[C@@]1([C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@@H]2CC2)C2=CC(=O)CC1 ORBBRLNBGBWXEF-OQWKOXFXSA-N 0.000 abstract 1
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
150000001441 androstanes Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000007363 ring formation reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Bakery Products And Manufacturing Methods Therefor (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO914710A 1990-11-30 1991-11-29 Analogifremgangsmåte for fremstilling av terapeutisk aktivt 2<beta>,19-(ethylen)androst-4-en-3,17-dion NO180304C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/621,184 US5166201A (en)	1990-11-30	1990-11-30	2β,19-ethylene bridged steroids as aromatase inhibitors

Publications (4)

Publication Number	Publication Date
NO914710D0 NO914710D0 (no)	1991-11-29
NO914710L true NO914710L (no)	1992-06-01
NO180304B NO180304B (no)	1996-12-16
NO180304C NO180304C (no)	1997-04-02

Family

ID=24489093

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO914710A NO180304C (no)	1990-11-30	1991-11-29	Analogifremgangsmåte for fremstilling av terapeutisk aktivt 2<beta>,19-(ethylen)androst-4-en-3,17-dion

Country Status (20)

Country	Link
US (1)	US5166201A (no)
EP (1)	EP0488383B1 (no)
JP (1)	JP3143876B2 (no)
KR (1)	KR100190776B1 (no)
CN (1)	CN1033975C (no)
AT (1)	ATE142639T1 (no)
AU (1)	AU635444B2 (no)
CA (1)	CA2056638C (no)
DE (1)	DE69122048T2 (no)
DK (1)	DK0488383T3 (no)
ES (1)	ES2094183T3 (no)
FI (1)	FI102073B (no)
GR (1)	GR3021981T3 (no)
HU (1)	HU210830B (no)
IE (1)	IE914168A1 (no)
IL (1)	IL100196A (no)
NO (1)	NO180304C (no)
NZ (1)	NZ240738A (no)
PT (1)	PT99661B (no)
ZA (1)	ZA919296B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19510862A1 (de) *	1995-03-16	1996-09-19	Schering Ag	Verwendung von Antiestrogenen zur männlichen Fertilitätskontrolle
EP1079859B1 (en)	1998-05-22	2010-07-14	The Board Of Trustees Of The Leland Stanford Junior University	Bifunctional molecules and therapies based thereon
CA2789262C (en)	2005-04-28	2016-10-04	Proteus Digital Health, Inc.	Pharma-informatics system
WO2007035716A2 (en)	2005-09-16	2007-03-29	Raptor Pharmaceutical Inc.	Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
CN110075069A (zh)	2009-05-06	2019-08-02	实验室护肤股份有限公司	包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3627756A (en) *	1970-04-23	1971-12-14	Searle & Co	N-dialkylaminoalkyl-n-(2{62 ,19-epoxy-5{60 -androstan-17{62 -yl)amines/formamides and 3{60 -halo derivatives thereof
US4322416A (en) *	1980-06-27	1982-03-30	Merrell Dow Pharmaceuticals Inc.	10-Alkynyl steroids
GB8501035D0 (en) *	1985-01-16	1985-02-20	Senior J	Prostaglandins
US4882322A (en) *	1988-10-27	1989-11-21	Merrell Dow Pharmaceuticals Inc.	3β,17β-hydroxy-substituted steroids and related steroidal compounds

1990
- 1990-11-30 US US07/621,184 patent/US5166201A/en not_active Expired - Fee Related
1991
- 1991-11-25 AU AU88128/91A patent/AU635444B2/en not_active Ceased
- 1991-11-25 ZA ZA919296A patent/ZA919296B/xx unknown
- 1991-11-26 NZ NZ240738A patent/NZ240738A/xx unknown
- 1991-11-28 IL IL10019691A patent/IL100196A/en not_active IP Right Cessation
- 1991-11-28 FI FI915623A patent/FI102073B/fi active IP Right Grant
- 1991-11-29 IE IE416891A patent/IE914168A1/en not_active Application Discontinuation
- 1991-11-29 CA CA002056638A patent/CA2056638C/en not_active Expired - Fee Related
- 1991-11-29 DE DE69122048T patent/DE69122048T2/de not_active Expired - Fee Related
- 1991-11-29 NO NO914710A patent/NO180304C/no not_active IP Right Cessation
- 1991-11-29 DK DK91120560.7T patent/DK0488383T3/da active
- 1991-11-29 PT PT99661A patent/PT99661B/pt not_active IP Right Cessation
- 1991-11-29 ES ES91120560T patent/ES2094183T3/es not_active Expired - Lifetime
- 1991-11-29 AT AT91120560T patent/ATE142639T1/de not_active IP Right Cessation
- 1991-11-29 EP EP91120560A patent/EP0488383B1/en not_active Expired - Lifetime
- 1991-11-29 JP JP03339535A patent/JP3143876B2/ja not_active Expired - Fee Related
- 1991-11-29 HU HU913739A patent/HU210830B/hu not_active IP Right Cessation
- 1991-11-30 CN CN91111251A patent/CN1033975C/zh not_active Expired - Fee Related
- 1991-11-30 KR KR1019910021920A patent/KR100190776B1/ko not_active Expired - Fee Related
1996
- 1996-12-11 GR GR960403414T patent/GR3021981T3/el unknown

Also Published As

Publication number	Publication date
DE69122048D1 (de)	1996-10-17
HU210830B (en)	1995-08-28
IL100196A (en)	1996-03-31
JPH04290898A (ja)	1992-10-15
AU8812891A (en)	1992-06-04
IL100196A0 (en)	1992-08-18
FI915623A0 (fi)	1991-11-28
DK0488383T3 (da)	1996-09-30
GR3021981T3 (en)	1997-03-31
AU635444B2 (en)	1993-03-18
US5166201A (en)	1992-11-24
IE914168A1 (en)	1992-06-03
DE69122048T2 (de)	1997-02-20
NO180304C (no)	1997-04-02
FI102073B1 (fi)	1998-10-15
ES2094183T3 (es)	1997-01-16
FI102073B (fi)	1998-10-15
KR100190776B1 (ko)	1999-06-01
KR920009842A (ko)	1992-06-25
CA2056638C (en)	2002-03-05
JP3143876B2 (ja)	2001-03-07
NO180304B (no)	1996-12-16
FI915623L (fi)	1992-05-31
CA2056638A1 (en)	1992-05-31
HUT59937A (en)	1992-07-28
PT99661A (pt)	1992-10-30
EP0488383B1 (en)	1996-09-11
HU913739D0 (en)	1992-02-28
EP0488383A1 (en)	1992-06-03
NZ240738A (en)	1993-11-25
ZA919296B (en)	1992-08-26
PT99661B (pt)	1999-05-31
NO914710D0 (no)	1991-11-29
CN1061974A (zh)	1992-06-17
ATE142639T1 (de)	1996-09-15
CN1033975C (zh)	1997-02-05

Publication	Publication Date	Title
GR900100380A (el)	1991-10-10	Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
ES529811A0 (es)	1984-11-16	Procedimiento para preparar derivados de n-fenil-benzamida
DE69838146D1 (de)	2007-09-06	Androgene steroidderivate und ein verfahren zur herstellung und verwendung derselben
NO914710L (no)	1992-06-01	Fremgangsmaate for fremstilling av 2beta,19-ethylenbroede steroider som aromataseinhibitorer
DE68911157D1 (de)	1994-01-20	Synthese von 6-Methylenandrosta-1,4-dien-3,17-dion-Derivate.
BG103271A (en)	2000-05-31	Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means
DK0559706T3 (da)	1997-09-08	2 beta,19-methylenamino-broforbundne steroider som aromataseinhibitorer.
ES2077867T3 (es)	1995-12-01	3-carbamoil-4-hidroxicumarinas antihelminticas y anticoccidiales, procedimiento de uso y composiciones.
ES2100315T3 (es)	1997-06-16	Nuevos esteroides 16-metilo sustituidos derivados de la pregna-1,4-dieno-3,20-diona, su preparacion, su aplicacion a la preparacion de esteroides 16-metileno y nuevos productos intermedios.
MXPA03000845A (es)	2004-04-05	Estrogenos substituidos por 16alfa-metilo o etilo.
NO911236L (no)	1991-10-03	Fremgangsmaate for fremstilling av haloethyl-substituerte steroidale enzyminhibitorer.
CA2032311A1 (en)	1991-06-21	2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase and 19-hydroxylase inhibitors
DK146007C (da)	1983-10-17	Analogifremgangsmaade til fremstilling af d-homosteroider
DK14083A (da)	1983-01-14	Analogifremgangsmaade til fremstilling af derivater af 4-desacetyl-vincaleucoblastin-c-3-carboxhydrazid
JPS52131580A (en)	1977-11-04	N-substituted pyridinium-2-sulfonylimines, containing same as active ingredient
ECSP951417A (es)	1996-07-16	Nuevos derivados de la eritromicina, su procedimiento de preparacion y su aplicación como medicamentos

Legal Events

Date	Code	Title	Description
2001-07-09	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MAY 2001