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NO871111L - Tertiaere hydroksyalkylxantiner, fremgangsmaate til deres fremstilling, legemidler som inneholder dem og deres anvendelse. - Google Patents

Tertiaere hydroksyalkylxantiner, fremgangsmaate til deres fremstilling, legemidler som inneholder dem og deres anvendelse.

Info

Publication number
NO871111L
NO871111L NO871111A NO871111A NO871111L NO 871111 L NO871111 L NO 871111L NO 871111 A NO871111 A NO 871111A NO 871111 A NO871111 A NO 871111A NO 871111 L NO871111 L NO 871111L
Authority
NO
Norway
Prior art keywords
hydroxylylxantines
tertiary
procedures
preparation
pharmaceuticals containing
Prior art date
Application number
NO871111A
Other languages
English (en)
Other versions
NO871111D0 (no
NO165803B (no
NO165803C (no
Inventor
Ulrich Gebert
Ismahan Okyayuz-Baklouti
Werner Thorwart
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO871111D0 publication Critical patent/NO871111D0/no
Publication of NO871111L publication Critical patent/NO871111L/no
Publication of NO165803B publication Critical patent/NO165803B/no
Publication of NO165803C publication Critical patent/NO165803C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO871111A 1985-07-19 1987-03-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive tertiaere hydroksyalkylxantiner. NO165803C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853525801 DE3525801A1 (de) 1985-07-19 1985-07-19 Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
PCT/EP1986/000401 WO1987000523A2 (en) 1985-07-19 1986-07-08 Tertiary hydroxyalkylxanthines, their manufacturing process, medicines containing them and use thereof

Publications (4)

Publication Number Publication Date
NO871111D0 NO871111D0 (no) 1987-03-18
NO871111L true NO871111L (no) 1987-03-18
NO165803B NO165803B (no) 1991-01-02
NO165803C NO165803C (no) 1991-04-10

Family

ID=6276182

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871111A NO165803C (no) 1985-07-19 1987-03-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive tertiaere hydroksyalkylxantiner.

Country Status (33)

Country Link
US (1) US4833146A (no)
EP (1) EP0268585B1 (no)
JP (1) JPH0788382B2 (no)
KR (1) KR950001019B1 (no)
CN (1) CN1026112C (no)
AR (1) AR244689A1 (no)
AT (1) ATE53211T1 (no)
AU (1) AU588350B2 (no)
BG (1) BG60767B2 (no)
CA (1) CA1262248A (no)
CS (1) CS272766B2 (no)
DD (1) DD261156A5 (no)
DE (2) DE3525801A1 (no)
DK (1) DK157867C (no)
ES (1) ES2001019A6 (no)
FI (1) FI89921C (no)
GR (1) GR861866B (no)
HU (1) HU198486B (no)
IE (1) IE59025B1 (no)
IL (1) IL79457A0 (no)
LT (1) LT3869B (no)
LV (1) LV5703A3 (no)
MA (1) MA20739A1 (no)
MX (1) MX9254A (no)
NO (1) NO165803C (no)
NZ (1) NZ216888A (no)
OA (1) OA08707A (no)
PH (1) PH26262A (no)
PT (1) PT83013B (no)
RU (1) RU2051918C1 (no)
TN (1) TNSN86111A1 (no)
WO (1) WO1987000523A2 (no)
ZA (1) ZA865374B (no)

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DE4019892A1 (de) * 1990-06-22 1992-01-02 Boehringer Ingelheim Kg Neue xanthinderivate
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US6420374B1 (en) 1990-11-30 2002-07-16 Fred Hutchinson Cancer Research Center Use of xanthines as immunosuppressants and to inhibit allograft reactions
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TW209834B (no) * 1991-12-11 1993-07-21 Hoechst Ag
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CA2112239C (en) * 1992-03-04 2000-05-09 James A. Bianco Enantiomeric hydroxylated xanthine compounds
EP0570831A2 (de) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation
US5288721A (en) * 1992-09-22 1994-02-22 Cell Therapeutics, Inc. Substituted epoxyalkyl xanthines
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
US5804584A (en) * 1992-11-16 1998-09-08 Cell Therapeutics, Inc. Therapeutic compounds containing a monocyclic five- to six- membered ring structure having one to two nitrogen atoms
US5473070A (en) * 1992-11-16 1995-12-05 Cell Therapeutics, Inc. Substituted long chain alcohol xanthine compounds
US6693105B1 (en) 1992-11-16 2004-02-17 Cell Therapeutics, Inc. Hydroxyl-containing compounds
US5866576A (en) * 1992-12-16 1999-02-02 Cell Therapeutics, Inc. Epoxide-containing compounds
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AU6092794A (en) * 1993-01-19 1994-08-15 Cell Therapeutics, Inc. Oxime-substituted therapeutic compounds
US5641783A (en) * 1993-11-12 1997-06-24 Cell Therapeutics, Inc. Substituted amino alcohol compounds
US5837703A (en) * 1993-03-31 1998-11-17 Cell Therapeutics, Inc. Amino-alcohol substituted cyclic compounds
US6020337A (en) * 1993-04-05 2000-02-01 Cell Therapeutics, Inc. Electronegative-substituted long chain xanthine compounds
CA2192470A1 (en) * 1994-01-14 1995-07-20 Paul A. Brown Method for treating diseases mediated by cellular proliferation in response to pdgf, egf, fgf and vegf
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
EP0746557A4 (en) * 1994-02-18 1997-05-02 Cell Therapeutics Inc INTRACELLULAR SIGNALING MEDIATORS
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
DE19540798A1 (de) * 1995-11-02 1997-05-07 Hoechst Ag Alkylxanthinphosphonate und Alkylxanthinphosphinoxide und deren Verwendung als Arzneimittel
US5965555A (en) * 1996-06-07 1999-10-12 Hoechst Aktiengesellschaft Xanthine compounds having terminally animated alkynol side chains
DE59708533D1 (de) * 1996-06-07 2002-11-28 Hoechst Ag Verwendung von Theophyllinderivaten zur Behandlung und Propylaxe von Schockzuständen, neue Xanthinverbindungen und Verfahren zu deren Herstellung
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
US6294350B1 (en) 1997-06-05 2001-09-25 Dalhousie University Methods for treating fibroproliferative diseases
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US6075029A (en) * 1998-01-02 2000-06-13 Cell Therapeutics, Inc. Xanthine modulators of metabolism of cellular P-450
US20030207901A1 (en) * 1999-07-27 2003-11-06 Cell Therapeutics, Inc. Hydroxyl-containing compounds
RU2157209C1 (ru) * 2000-03-23 2000-10-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Улучшающее мозговое кровообращение, антиагрегатное средство и способ его получения
DE10042152A1 (de) * 2000-08-26 2002-03-28 Basf Coatings Ag Mit aktinischer Strahlung aktivierbares Thixotropierungsmittel, Verfahren zu seiner Herstellung und seine Verwendung
DE10122390A1 (de) * 2001-05-09 2002-11-28 Basf Coatings Ag Carbamat-und/oder Allophanatgruppen enthaltende, thermisch härtbare, thixotrope Gemische
DE10139262C1 (de) * 2001-08-09 2003-01-02 Basf Coatings Ag Rheologiehilfsmittel, Verfahren zu seiner Herstellung und seine Verwendung
US20050119422A1 (en) * 2002-04-24 2005-06-02 Basf Corporation Thermally curable, thixotropic mixtures containing carbamate and/or allophanate groups
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US2517410A (en) * 1947-08-15 1950-08-01 Searle & Co Hydroxy alkyl xanthines and the production thereof
FR1211333A (fr) * 1955-10-19 1960-03-15 Boehringer Sohn Ingelheim Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines
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Also Published As

Publication number Publication date
JPH0788382B2 (ja) 1995-09-27
ATE53211T1 (de) 1990-06-15
LT3869B (en) 1996-04-25
JPS63501149A (ja) 1988-04-28
NO871111D0 (no) 1987-03-18
DD261156A5 (de) 1988-10-19
BG60767B2 (bg) 1996-02-29
PH26262A (en) 1992-04-01
FI880174A0 (fi) 1988-01-15
DK139287A (da) 1987-03-18
EP0268585A1 (de) 1988-06-01
CA1262248A (en) 1989-10-10
IL79457A0 (en) 1986-10-31
AU6143986A (en) 1987-02-10
FI89921C (fi) 1993-12-10
CS272766B2 (en) 1991-02-12
MA20739A1 (fr) 1987-04-01
US4833146A (en) 1989-05-23
HU198486B (en) 1989-10-30
CN1026112C (zh) 1994-10-05
KR870700623A (ko) 1987-12-30
FI880174L (fi) 1988-01-15
NO165803B (no) 1991-01-02
IE59025B1 (en) 1993-12-15
LV5703A3 (lv) 1995-02-20
KR950001019B1 (ko) 1995-02-07
ZA865374B (en) 1987-02-25
PT83013B (pt) 1989-01-30
EP0268585B1 (de) 1990-05-30
AR244689A1 (es) 1993-11-30
DK157867C (da) 1990-07-30
AU588350B2 (en) 1989-09-14
DK139287D0 (da) 1987-03-18
FI89921B (fi) 1993-08-31
LTIP1467A (en) 1995-05-25
NO165803C (no) 1991-04-10
OA08707A (en) 1989-03-31
ES2001019A6 (es) 1988-04-16
PT83013A (de) 1986-08-01
CS545386A2 (en) 1990-04-11
DE3525801A1 (de) 1987-01-22
WO1987000523A3 (en) 1987-02-26
RU2051918C1 (ru) 1996-01-10
GR861866B (en) 1986-11-17
CN86105835A (zh) 1987-01-14
IE861917L (en) 1987-01-19
NZ216888A (en) 1989-05-29
DE3671627D1 (de) 1990-07-05
MX9254A (es) 1993-06-01
DK157867B (da) 1990-02-26
HUT47274A (en) 1989-02-28
TNSN86111A1 (fr) 1990-01-01
WO1987000523A2 (en) 1987-01-29

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