NO874550D0 - Fremgangsmaate for fremstilling av estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3(4h)-on og beslektede forbindelser. - Google Patents

Fremgangsmaate for fremstilling av estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3(4h)-on og beslektede forbindelser.

Info

Publication number: NO874550D0
Authority: NO; Norway
Prior art keywords: quinolizin; methano; hexahydro; hydroxy; procedure
Prior art date: 1986-11-03

Application number

NO874550A

Other languages

English (en)

Other versions

NO165922B (no

NO165922C (no

NO874550L (no

Inventor

Maurice Ward Gittos

Original Assignee

Merrell Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-03

Filing date

1987-11-02

Publication date

1987-11-02

1987-11-02 Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc

1987-11-02 Publication of NO874550D0 publication Critical patent/NO874550D0/no

1988-05-04 Publication of NO874550L publication Critical patent/NO874550L/no

1991-01-21 Publication of NO165922B publication Critical patent/NO165922B/no

1991-05-02 Publication of NO165922C publication Critical patent/NO165922C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO874550A 1986-11-03 1987-11-02 Analogifremgangsmaate for fremstilling av terapeutisk aktive estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3-(4h)-on og beslektede forbindelser. NO165922C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US92661986A	1986-11-03	1986-11-03

Publications (4)

Publication Number	Publication Date
NO874550D0 true NO874550D0 (no)	1987-11-02
NO874550L NO874550L (no)	1988-05-04
NO165922B NO165922B (no)	1991-01-21
NO165922C NO165922C (no)	1991-05-02

Family

ID=25453460

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO874550A NO165922C (no)	1986-11-03	1987-11-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3-(4h)-on og beslektede forbindelser.
NO1999020C NO1999020I1 (no)	1986-11-03	1999-08-26	Dolasetron

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO1999020C NO1999020I1 (no)	1986-11-03	1999-08-26	Dolasetron

Country Status (21)

Country	Link
EP (1)	EP0266730B1 (no)
JP (2)	JP2542225B2 (no)
KR (1)	KR950011737B1 (no)
CN (1)	CN1021654C (no)
AR (1)	AR246264A1 (no)
AT (1)	ATE109779T1 (no)
AU (1)	AU600318B2 (no)
CA (1)	CA1329203C (no)
DE (2)	DE3750359T2 (no)
DK (1)	DK171116B1 (no)
ES (1)	ES2061469T3 (no)
FI (1)	FI87786C (no)
HU (1)	HU197008B (no)
IE (1)	IE63670B1 (no)
IL (1)	IL84309A (no)
NL (1)	NL970043I2 (no)
NO (2)	NO165922C (no)
NZ (1)	NZ222349A (no)
PH (2)	PH24664A (no)
PT (1)	PT86060B (no)
ZA (1)	ZA878096B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5011846A (en) *	1988-02-23	1991-04-30	Merrell Dow Pharmaceuticals Inc.	Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof
EP0329903A1 (en) *	1988-02-23	1989-08-30	Merrell Dow Pharmaceuticals Inc.	Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of glaucoma
EP0329904A1 (en) *	1988-02-23	1989-08-30	Merrell Dow Pharmaceuticals Inc.	Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety
EP0329902A1 (en) *	1988-02-23	1989-08-30	Merrell Dow Pharmaceuticals Inc.	Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of psychosis
EP0329905A1 (en) *	1988-02-23	1989-08-30	Merrell Dow Pharmaceuticals Inc.	Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for increasing gastric motility
ES2080727T3 (es) *	1988-02-23	1996-02-16	Merrell Pharma Inc	Uso de quinolizina y derivados de quinolizinona en la fabricacion de medicamentos.
EP0330788A1 (en) *	1988-03-01	1989-09-06	Merrell Dow Pharmaceuticals Inc.	Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia
ZA893008B (en) *	1988-04-29	1989-12-27	Merrell Dow Pharma	Process for preparing indole-3-carboxylic acid esters of transhexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one
GB8928837D0 (en) *	1989-12-21	1990-02-28	Beecham Group Plc	Pharmaceuticals
EP0492020A1 (en) *	1990-12-21	1992-07-01	Merrell Dow Pharmaceuticals Inc.	Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds for treating cognitive disorders
IL136812A0 (en) *	1997-12-17	2001-06-14	Biocryst Pharm Inc	Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
CN100390172C (zh) *	2004-09-10	2008-05-28	成都欣捷高新技术开发有限公司	一种甲磺酸多拉司琼晶型及其制备方法
WO2006056081A1 (de) *	2004-11-25	2006-06-01	Cilag Ltd.	Verfahren zur herstellung von estern von hexahydro-8-hydroxy-2,6-methano-2h-chinolizin-3(4h)-on
ES2314927T3 (es) *	2005-07-06	2009-03-16	Inke, S.A.	Procedimiento para la obtencion de un compuesto farmaceuticamente activo, sus intermedios de sintesis y procedimientos para la obtencion de los mismos.
ES2264901B1 (es)	2005-07-06	2007-12-01	Inke, S.A.	Procedimiento para la obtencion de un compuesto farmaceuticamente activo, sus intermedios de sintesis y procedimiento para la obtencion de los mismos.
EP1861397A2 (en) *	2006-01-05	2007-12-05	TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság	Production of dolasetron
ES2389261T3 (es)	2007-11-13	2012-10-24	Inke, S.A.	Compuestos intermedios útiles para preparar dolasetrón
EP2253316B1 (en)	2009-05-20	2013-08-14	INSERM (Institut National de la Santé et de la Recherche Médicale)	Serotonin 5-HT3 receptor antagonists for use in the treatment or prevention of an inner ear pathology with vestibular deficits
WO2010133663A1 (en)	2009-05-20	2010-11-25	INSERM (Institut National de la Santé et de la Recherche Médicale)	Serotonin 5-ht3 receptor antagonists for use in the treatment of lesional vestibular disorders
US20180250270A1 (en)	2015-09-11	2018-09-06	Chase Pharmaceuticals Corporation	Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system
CN108976230A (zh) *	2018-06-18	2018-12-11	东莞市联洲知识产权运营管理有限公司	一种基于石墨烯活化制备甲磺酸多拉司琼关键中间体的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
WO1985001048A1 (en) *	1983-08-26	1985-03-14	Sandoz Ag	Aromatic esters or amides of carboxylic acid and sulfonic acid
ATE86110T1 (de) *	1984-12-20	1993-03-15	Sandoz Ag	Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten.

1987
- 1987-10-28 ZA ZA878096A patent/ZA878096B/xx unknown
- 1987-10-29 FI FI874768A patent/FI87786C/fi not_active IP Right Cessation
- 1987-10-29 CA CA000550612A patent/CA1329203C/en not_active Expired - Lifetime
- 1987-10-29 IL IL84309A patent/IL84309A/xx not_active IP Right Cessation
- 1987-10-29 NZ NZ222349A patent/NZ222349A/xx unknown
- 1987-10-30 AR AR87309166A patent/AR246264A1/es active
- 1987-10-30 PH PH36006A patent/PH24664A/en unknown
- 1987-11-02 JP JP62275894A patent/JP2542225B2/ja not_active Expired - Lifetime
- 1987-11-02 AT AT87116119T patent/ATE109779T1/de not_active IP Right Cessation
- 1987-11-02 IE IE295587A patent/IE63670B1/en not_active IP Right Cessation
- 1987-11-02 HU HU874918A patent/HU197008B/hu unknown
- 1987-11-02 NO NO874550A patent/NO165922C/no not_active IP Right Cessation
- 1987-11-02 AU AU80596/87A patent/AU600318B2/en not_active Expired
- 1987-11-02 DE DE3750359T patent/DE3750359T2/de not_active Expired - Lifetime
- 1987-11-02 CN CN87107629A patent/CN1021654C/zh not_active Expired - Lifetime
- 1987-11-02 EP EP87116119A patent/EP0266730B1/en not_active Expired - Lifetime
- 1987-11-02 PT PT86060A patent/PT86060B/pt unknown
- 1987-11-02 ES ES87116119T patent/ES2061469T3/es not_active Expired - Lifetime
- 1987-11-02 DE DE1997175092 patent/DE19775092I2/de active Active
- 1987-11-02 DK DK572887A patent/DK171116B1/da not_active IP Right Cessation
- 1987-11-03 KR KR1019870012286A patent/KR950011737B1/ko not_active Expired - Lifetime
1990
- 1990-01-02 PH PH39830A patent/PH26261A/en unknown
1996
- 1996-02-27 JP JP8065408A patent/JP2657267B2/ja not_active Expired - Lifetime
1997
- 1997-12-17 NL NL970043C patent/NL970043I2/nl unknown
1999
- 1999-08-26 NO NO1999020C patent/NO1999020I1/no unknown

Also Published As

Publication number	Publication date
AU600318B2 (en)	1990-08-09
EP0266730B1 (en)	1994-08-10
PH24664A (en)	1990-09-07
NO165922B (no)	1991-01-21
HUT45055A (en)	1988-05-30
EP0266730A1 (en)	1988-05-11
NZ222349A (en)	1990-05-28
CA1329203C (en)	1994-05-03
NL970043I1 (nl)	1998-03-02
AR246264A1 (es)	1994-07-29
IE63670B1 (en)	1995-05-31
JP2657267B2 (ja)	1997-09-24
FI874768A0 (fi)	1987-10-29
JPH0977769A (ja)	1997-03-25
FI874768A7 (fi)	1988-05-04
ZA878096B (en)	1988-04-26
DE3750359D1 (de)	1994-09-15
PH26261A (en)	1992-04-01
PT86060A (en)	1987-12-01
IE872955L (en)	1988-05-03
DK171116B1 (da)	1996-06-17
KR880006240A (ko)	1988-07-22
HU197008B (en)	1989-02-28
DE3750359T2 (de)	1994-12-08
AU8059687A (en)	1988-05-05
NL970043I2 (nl)	1998-10-01
JPS63258476A (ja)	1988-10-25
ES2061469T3 (es)	1994-12-16
PT86060B (pt)	1990-07-31
CN87107629A (zh)	1988-06-15
FI87786C (fi)	1993-02-25
DK572887A (da)	1988-05-04
ATE109779T1 (de)	1994-08-15
IL84309A (en)	1991-09-16
FI87786B (fi)	1992-11-13
NO1999020I1 (no)	1999-08-26
JP2542225B2 (ja)	1996-10-09
DK572887D0 (da)	1987-11-02
NO165922C (no)	1991-05-02
CN1021654C (zh)	1993-07-21
DE19775092I2 (de)	2001-11-22
NO874550L (no)	1988-05-04
KR950011737B1 (ko)	1995-10-09

Publication	Publication Date	Title
NO874550D0 (no)	1987-11-02	Fremgangsmaate for fremstilling av estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3(4h)-on og beslektede forbindelser.
NO882762D0 (no)	1988-06-22	Fremgangsmaate for fremstilling av antihypertensive og antiarytmiske forbindelser.
NO870409L (no)	1987-08-04	Fremgangsmaate for spaltning av 1-aminoindaner.
NO880910D0 (no)	1988-03-01	Fremgangsmaate for fremstilling av chromonderivater.
NO884900D0 (no)	1988-11-03	Fremgangsmaate for fremstilling av ginkolid-derivater.
NO170022C (no)	1992-09-02	Fremgangsmaate for fremstilling av sialocylglycerolipider.
NO882730D0 (no)	1988-06-21	Fremgangsmaate for fremstilling av aminocyklopentyletere.
NO872587D0 (no)	1987-06-19	Forbedret limpreparat og fremgangsmaate for fremstilling av dette.
NO881713D0 (no)	1988-04-20	Fremgangsmaate for fremstilling av di-t-butylfenyl-alkyl og benzylethere.
NO872255D0 (no)	1987-05-29	Fremgangsmaate for dekaffinering av raakaffe.
NO882336L (no)	1988-11-30	Fremgangsmaate for fremstilling av 5-metoksyalkylammoniun-tetrahydrofuraner og tetrahydrotiofener.
NO870828L (no)	1987-08-31	Fremgangsmte for fremstilling av biskarbamater.
NO882028L (no)	1988-11-30	Fremgangsmaate for fremstilling av cardiotone, tricykliskeimidazoloner.
NO880802D0 (no)	1988-02-24	Mellomprodukter og fremgangsmaater til fremstilling av antihyperkolesterolemiske tetrazolforbindelser.
NO891712L (no)	1989-10-27	Fremgangsmaate for fremstilling av estere av hexahydro-8-hydroxy-2,6-methano-2h-kinolizin-3(4h)-on og beslektede forbindelser.
NO874958D0 (no)	1987-11-27	Fremgangsmaate for fremstilling av 1-aryloksy-3-amino-2-propanoler.
NO880834D0 (no)	1988-02-25	Fremgangsmaate for fremstilling av heterocyclyl-2-propyn-1-aminer.
NO871721D0 (no)	1987-04-24	Fremgangsmaate for fremstilling av ergolenderivater.
NO883398D0 (no)	1988-08-01	Fremgangsmaate for fremstilling av benzoksazinderivater.
NO884100L (no)	1989-03-17	Fremgangsmaate for fremstilling av halogentiazolderivater.
NO880167D0 (no)	1988-01-15	Fremgangsmaate for fremstilling av benzotiazindioksyd-derivater.
NO883363D0 (no)	1988-07-29	Nytt diosminderivat og fremgangsmaate for fremstilling av dette.
NO872765L (no)	1989-01-03	Beta-laktam-sammensetning, og framgangsmaate for framstilling av denne.
NO870330D0 (no)	1987-01-27	Fremgangsmaate for fremstilling av hydrogen.
NO170276C (no)	1992-09-30	3-hydroxypyrazolforbindelser og fremgangsmaate for fremstilling av slike

Legal Events

Date	Code	Title	Description
2007-12-03	MK1K	Patent expired
2011-10-10	MK1K	Patent expired