[go: up one dir, main page]

NO303205B1 - FremgangsmÕte for fremstilling av lipidkompleksoppslemming - Google Patents

FremgangsmÕte for fremstilling av lipidkompleksoppslemming Download PDF

Info

Publication number
NO303205B1
NO303205B1 NO913816A NO913816A NO303205B1 NO 303205 B1 NO303205 B1 NO 303205B1 NO 913816 A NO913816 A NO 913816A NO 913816 A NO913816 A NO 913816A NO 303205 B1 NO303205 B1 NO 303205B1
Authority
NO
Norway
Prior art keywords
lipid
compound
slurry
solution
solvent
Prior art date
Application number
NO913816A
Other languages
English (en)
Norwegian (no)
Other versions
NO913816L (no
NO913816D0 (no
Inventor
Jr Francis C Szoka
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of NO913816D0 publication Critical patent/NO913816D0/no
Publication of NO913816L publication Critical patent/NO913816L/no
Publication of NO303205B1 publication Critical patent/NO303205B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO913816A 1989-03-31 1991-09-27 FremgangsmÕte for fremstilling av lipidkompleksoppslemming NO303205B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33260989A 1989-03-31 1989-03-31
US33405589A 1989-04-05 1989-04-05
PCT/US1990/001646 WO1990011780A1 (fr) 1989-03-31 1990-03-28 Preparation de compositions complexes de liposomes et de lipides

Publications (3)

Publication Number Publication Date
NO913816D0 NO913816D0 (no) 1991-09-27
NO913816L NO913816L (no) 1991-11-26
NO303205B1 true NO303205B1 (no) 1998-06-15

Family

ID=26988293

Family Applications (1)

Application Number Title Priority Date Filing Date
NO913816A NO303205B1 (no) 1989-03-31 1991-09-27 FremgangsmÕte for fremstilling av lipidkompleksoppslemming

Country Status (12)

Country Link
EP (1) EP0467954B1 (fr)
JP (1) JP2798302B2 (fr)
AT (1) ATE137403T1 (fr)
AU (1) AU638245B2 (fr)
CA (1) CA2050679C (fr)
DE (1) DE69026820T2 (fr)
DK (1) DK0467954T3 (fr)
ES (1) ES2087151T3 (fr)
HK (1) HK1000912A1 (fr)
HU (1) HU208070B (fr)
NO (1) NO303205B1 (fr)
WO (1) WO1990011780A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
JPH0363298A (ja) * 1989-07-31 1991-03-19 Green Cross Corp:The コロニー形成刺激因子・脂質複合体
FR2653015B1 (fr) * 1989-10-12 1993-10-29 Oreal Composition cosmetique ou pharmaceutique pour application topique contenant au moins un derive retinouide et au moins un derive de pyrimidine, son utilisation comme medicament et procede de traitement correspondant.
DE69130832T2 (de) 1990-11-16 1999-10-07 Nippon Shinyaku Co., Ltd. Injizierbare amphotericin b enthaltende dispersion
DE4238779A1 (de) * 1992-11-12 1994-05-19 Max Delbrueck Centrum Lyotrophe Mesophasen und ihre Anwendung in der Pharmazie, der Kosmetik und der Dermatologie
PT707472E (pt) 1993-07-08 2001-07-31 Liposome Co Inc Processo para controlar a dimensao de lipossomas
DE69434623T2 (de) * 1993-09-29 2006-07-27 Dsm Ip Assets B.V. Modifizierte Formen des Natamycins, Verfahren zu ihrer Herstellung und sie enthaltende antifungale Zusammensetzungen
EP0840744A4 (fr) * 1995-06-07 1999-03-10 Genta Inc Nouveaux lipides cationiques a base d'acide phosphonique
JP2002532535A (ja) * 1998-12-22 2002-10-02 アメリカ合衆国 水不溶性薬剤送達システム
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
EP1334718A4 (fr) 2000-10-26 2007-07-18 Senju Pharma Co Composition medicamenteuse contenant un compose dipeptidyl aldehyde
EP1343476B1 (fr) * 2000-12-01 2008-05-28 Biomira Inc. Preparation de liposomes de grande taille par perfusion dans du peg
IS6389A (is) * 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra
AU2008227852B2 (en) * 2007-03-19 2011-02-24 Fresenius Kabi Oncology Ltd. Proliposomal and liposomal compositions
EP2219587A4 (fr) * 2007-11-14 2012-11-21 Univ California Lipides amphiphiles modifiés par un stérol
DK2344198T3 (da) * 2008-09-27 2020-11-30 Jina Pharmaceuticals Inc Lipidbaserede farmaceutiske præparater til topisk anvendelse
CN102573889B (zh) * 2010-07-14 2014-10-22 中国医学科学院药物研究所 一种胰岛素的脂质复合物及其制备方法和制剂
US10004759B2 (en) 2014-08-04 2018-06-26 Zoneone Pharma, Inc. Remote loading of sparingly water-soluble drugs into lipid vesicles
CN113616798A (zh) * 2021-09-06 2021-11-09 天津农学院 一种甲苯咪唑脂质复合物、制备方法和应用
CN115177590A (zh) * 2022-04-20 2022-10-14 南昌大学抚州医学院 一种甲苯达唑类脂质体的制备方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
JPS60240634A (ja) 1984-05-08 1985-11-29 関　則雄 飲み干し容易なコツプ
US4619913A (en) * 1984-05-29 1986-10-28 Matrix Pharmaceuticals, Inc. Treatments employing drug-containing matrices for introduction into cellular lesion areas
AU598002B2 (en) * 1986-07-15 1990-06-14 Cilag Ltd. Method of preparing single bilayered liposomes
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4812312A (en) * 1987-03-03 1989-03-14 Board Of Regents Of The University Of Texas System Liposome-incorporated nystatin
NZ223660A (en) * 1987-03-05 1990-11-27 Liposome Co Inc Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity

Also Published As

Publication number Publication date
HUT59818A (en) 1992-07-28
AU5434590A (en) 1990-11-05
EP0467954A4 (en) 1992-06-03
ATE137403T1 (de) 1996-05-15
HU208070B (en) 1993-08-30
JP2798302B2 (ja) 1998-09-17
HU903559D0 (en) 1991-12-30
EP0467954A1 (fr) 1992-01-29
DK0467954T3 (da) 1996-05-28
EP0467954B1 (fr) 1996-05-01
AU638245B2 (en) 1993-06-24
HK1000912A1 (en) 1998-05-08
CA2050679A1 (fr) 1990-10-01
NO913816L (no) 1991-11-26
DE69026820T2 (de) 1996-11-28
WO1990011780A1 (fr) 1990-10-18
NO913816D0 (no) 1991-09-27
CA2050679C (fr) 1998-09-22
DE69026820D1 (de) 1996-06-05
ES2087151T3 (es) 1996-07-16
JPH04506207A (ja) 1992-10-29

Similar Documents

Publication Publication Date Title
US5077057A (en) Preparation of liposome and lipid complex compositions
US5567434A (en) Preparation of liposome and lipid complex compositions
US5277914A (en) Preparation of liposome and lipid complex compositions
NO303205B1 (no) FremgangsmÕte for fremstilling av lipidkompleksoppslemming
Rigaud et al. Reconstitution of membrane proteins into liposomes: application to energy-transducing membrane proteins
Vemuri et al. Preparation and characterization of liposomes as therapeutic delivery systems: a review
EP0240346B1 (fr) Procédé pour la préparation de liposomes
EP0781123B1 (fr) Preparation de liposomes multivesiculaires pour la liberation lente d'agents actifs
HK1000912B (en) Preparation of liposome and lipid complex compositions
Guo et al. Novel antifungal drug delivery: stable amphotericin B-cholesteryl sulfate discs
US5874104A (en) Treatment of systemic fungal infections with phospholipid particles encapsulating polyene antibiotics
JP2911814B2 (ja) リポソーム性の水中分散する経口投与可能な固体乾燥治療用処方の製造方法
EP0380584B1 (fr) Poudres pre-liposomiques de macrolide de polyene
EP0280503B1 (fr) Liposomes multivésiculaires contenant une substance biologiquement active en présence d'un chlorhydrate
EP0500143A2 (fr) Composition pharmaceutique à base de phosphate d'aminoglycoside
KR20010030892A (ko) 공동-동결건조보존방법을 이용한 펩티드/지질 복합체
CN1044093C (zh) 低毒性药物类脂制剂
EP2368627A1 (fr) Procédé de fabrication d'un liposome et procédé de dissolution de cholestérol
CA1308025C (fr) Composition de phospholipide
US20020016302A1 (en) Liposomal antitumor drug and its preparation
JPH0114A (ja) リポソーム製剤およびその製造法
AU641532B2 (en) Liposome preparation and antibiotic
HK71592A (en) Phospholipid composition