NO300206B1 - Fremgangsmåte for fremstilling av terapeutisk aktive benzosyrederivater, samt bisykliske amidforbindelser - Google Patents

Fremgangsmåte for fremstilling av terapeutisk aktive benzosyrederivater, samt bisykliske amidforbindelser Download PDF

Info

Publication number: NO300206B1
Authority: NO; Norway
Prior art keywords: compound; lower alkyl; benzoic acid; general formula; formula
Prior art date: 1990-03-20

Application number

NO914519A

Other languages

English (en)

Norwegian (no)

Other versions

NO914519D0 (no

NO914519L (no

Inventor

Yoshinori Hamada

Isamu Yamada

Masaaki Uenaka

Teruo Sakata

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-20

Filing date

1991-11-19

Publication date

1997-04-28

1991-11-19 Application filed by Shionogi & Co filed Critical Shionogi & Co

1991-11-19 Publication of NO914519D0 publication Critical patent/NO914519D0/no

1992-01-07 Publication of NO914519L publication Critical patent/NO914519L/no

1997-04-28 Publication of NO300206B1 publication Critical patent/NO300206B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Obesity (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Hematology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Developing Agents For Electrophotography (AREA)
Paper (AREA)

NO914519A 1990-03-20 1991-11-19 Fremgangsmåte for fremstilling av terapeutisk aktive benzosyrederivater, samt bisykliske amidforbindelser NO300206B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP7143390		1990-03-20
PCT/JP1991/000350 WO1991014673A1 (fr)	1990-03-20	1991-03-15	Procede nouveau pour fabriquer un derive d'acide benzoique

Publications (3)

Publication Number	Publication Date
NO914519D0 NO914519D0 (no)	1991-11-19
NO914519L NO914519L (no)	1992-01-07
NO300206B1 true NO300206B1 (no)	1997-04-28

Family

ID=13460393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO914519A NO300206B1 (no)	1990-03-20	1991-11-19	Fremgangsmåte for fremstilling av terapeutisk aktive benzosyrederivater, samt bisykliske amidforbindelser

Country Status (14)

Country	Link
US (1)	US5214202A (ja)
EP (1)	EP0478787B1 (ja)
JP (2)	JP3001632B2 (ja)
KR (1)	KR960014911B1 (ja)
AT (1)	ATE115946T1 (ja)
AU (1)	AU628732B2 (ja)
DE (1)	DE69106098T2 (ja)
DK (1)	DK0478787T3 (ja)
ES (1)	ES2069285T3 (ja)
FI (1)	FI915445A7 (ja)
GR (1)	GR3015138T3 (ja)
HU (2)	HU208417B (ja)
NO (1)	NO300206B1 (ja)
WO (1)	WO1991014673A1 (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5264578A (en)	1987-03-20	1993-11-23	Allergan, Inc.	Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
US5648514A (en)	1994-12-29	1997-07-15	Allergan	Substituted acetylenes having retinoid-like biological activity
US5534641A (en)	1994-12-29	1996-07-09	Allergan	Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
US5917082A (en)	1995-06-06	1999-06-29	Allergan Sales, Inc.	2,4-pentadienoic acid derivatives having retinoid-like biological activity
US5675033A (en)	1995-06-06	1997-10-07	Allergan	2,4-pentadienoic acid derivatives having retinoid-like biological activity
US5958954A (en)	1995-09-01	1999-09-28	Allergan Sales, Inc.	Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US5776699A (en) *	1995-09-01	1998-07-07	Allergan, Inc.	Method of identifying negative hormone and/or antagonist activities
US5952345A (en)	1995-09-01	1999-09-14	Allergan Sales, Inc.	Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US6218128B1 (en)	1997-09-12	2001-04-17	Allergan Sales, Inc.	Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
US6008204A (en)	1995-09-01	1999-12-28	Allergan Sales, Inc.	Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
US6942980B1 (en)	1995-09-01	2005-09-13	Allergan, Inc.	Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
US5675024A (en)	1995-11-22	1997-10-07	Allergan	Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
US5773594A (en)	1996-06-21	1998-06-30	Allergan	Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US6555690B2 (en)	1996-06-21	2003-04-29	Allergan, Inc.	Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5741896A (en)	1996-06-21	1998-04-21	Allergan	O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
US5763635A (en)	1996-06-21	1998-06-09	Allergan	Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity
US5728846A (en)	1996-12-12	1998-03-17	Allergan	Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives
US6037488A (en)	1997-04-19	2000-03-14	Allergan Sales, Inc.	Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
US5919970A (en)	1997-04-24	1999-07-06	Allergan Sales, Inc.	Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
CN1817856A (zh) *	2000-09-01	2006-08-16	东光药品工业株式会社	苯甲酸衍生物结晶的制造方法
US6620963B1 (en)	2002-09-19	2003-09-16	Allergan, Inc.	TRICYCLO[6.2.202,7]DODECA-2(7),3,5-TRIEN-4-CARBONYLAMINO-PHENYL AND TRICYCLO[6.2.202,7]DODECA-2(7),3,5-TRIEN-4-CARBONYLAMINO-HETEROARYL AND RELATED COMPOUNDS HAVING RARα RECEPTOR SELECTIVE BIOLOGICAL ACTIVITY
US6727277B1 (en)	2002-11-12	2004-04-27	Kansas State University Research Foundation	Compounds affecting cholesterol absorption
CN101200435B (zh) *	2006-12-12	2011-12-07	江苏恒瑞医药股份有限公司	他米巴罗汀ⅱ型结晶的制备方法
NZ580209A (en)	2007-03-30	2011-11-25	Tmrc Co Ltd	Tamibarotene capsule preparation
WO2009114966A1 (zh) *	2008-03-19	2009-09-24	江苏恒瑞医药股份有限公司	他米巴罗汀ii型结晶的制备方法
CN101665449B (zh) *	2009-09-24	2012-12-12	山东大学	他米巴罗汀的水溶性前药及其制备方法与应用
CN102633673A (zh) *	2012-03-30	2012-08-15	上海共价化学科技有限公司	他米巴罗汀的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2500157C2 (de) *	1975-01-03	1983-09-15	Hoechst Ag, 6230 Frankfurt	N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung
US4227014A (en) *	1978-02-27	1980-10-07	American Cyanamid Company	4-[(Cycloalkyl or cycloalkenyl substituted)amino, alkylamino or alkenylamino]benzoic acids and salts thereof
DK214679A (da) *	1978-06-09	1979-12-10	Chugai Pharmaceutical Co Ltd	Terephthalsyremonoamid derivater fremgangsmaade til deres fremstilling samt antiallergiske midler indeholdende disse
JPS6176440A (ja) *	1984-09-19	1986-04-18	Koichi Shiyudo	安息香酸誘導体
US4808631A (en) *	1986-11-07	1989-02-28	Hoffmann-La Roche Inc.	Aromatic acid derivatives
US4989090A (en) *	1989-04-05	1991-01-29	Yves C. Faroudja	Television scan line doubler including temporal median filter

1991
- 1991-03-15 AU AU74826/91A patent/AU628732B2/en not_active Ceased
- 1991-03-15 JP JP3505852A patent/JP3001632B2/ja not_active Expired - Lifetime
- 1991-03-15 US US07/778,985 patent/US5214202A/en not_active Expired - Lifetime
- 1991-03-15 HU HU913801A patent/HU208417B/hu not_active IP Right Cessation
- 1991-03-15 AT AT91906248T patent/ATE115946T1/de not_active IP Right Cessation
- 1991-03-15 EP EP91906248A patent/EP0478787B1/en not_active Expired - Lifetime
- 1991-03-15 FI FI915445A patent/FI915445A7/fi unknown
- 1991-03-15 DK DK91906248.9T patent/DK0478787T3/da active
- 1991-03-15 HU HU9202856A patent/HU210300B/hu not_active IP Right Cessation
- 1991-03-15 ES ES91906248T patent/ES2069285T3/es not_active Expired - Lifetime
- 1991-03-15 DE DE69106098T patent/DE69106098T2/de not_active Expired - Lifetime
- 1991-03-15 KR KR1019910701646A patent/KR960014911B1/ko not_active Expired - Fee Related
- 1991-03-15 WO PCT/JP1991/000350 patent/WO1991014673A1/ja not_active Ceased
- 1991-11-19 NO NO914519A patent/NO300206B1/no not_active IP Right Cessation
1995
- 1995-02-22 GR GR950400358T patent/GR3015138T3/el unknown
1999
- 1999-07-16 JP JP11203717A patent/JP3076569B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO914519D0 (no)	1991-11-19
ES2069285T3 (es)	1995-05-01
HUT61270A (en)	1992-12-28
EP0478787B1 (en)	1994-12-21
AU628732B2 (en)	1992-09-17
NO914519L (no)	1992-01-07
HU913801D0 (en)	1992-07-28
JP3076569B2 (ja)	2000-08-14
GR3015138T3 (en)	1995-05-31
EP0478787A1 (en)	1992-04-08
WO1991014673A1 (fr)	1991-10-03
EP0478787A4 (en)	1992-07-01
FI915445A0 (fi)	1991-11-18
KR960014911B1 (ko)	1996-10-21
KR920702342A (ko)	1992-09-03
ATE115946T1 (de)	1995-01-15
DE69106098D1 (de)	1995-02-02
JP2000034262A (ja)	2000-02-02
US5214202A (en)	1993-05-25
DE69106098T2 (de)	1995-05-24
AU7482691A (en)	1991-10-21
HU208417B (en)	1993-10-28
HUT61272A (en)	1992-12-28
HU210300B (en)	1995-03-28
DK0478787T3 (da)	1995-02-20
HU9202856D0 (en)	1992-11-30
JP3001632B2 (ja)	2000-01-24
FI915445A7 (fi)	1991-11-18

Publication	Publication Date	Title
NO300206B1 (no)	1997-04-28	Fremgangsmåte for fremstilling av terapeutisk aktive benzosyrederivater, samt bisykliske amidforbindelser
JPWO1991014673A1 (ja)	1992-07-02	安息香酸誘導体の新規製造法
US2731471A (en)	1956-01-17	Nxg hi
IL22818A (en)	1969-02-27	4-Alcohol Acetic Acetic Acids and their History, Processes for Preparation and Pharmaceutical Preparations Containing Them
US2856429A (en)	1958-10-14	Process for the preparation of nitramines
HU193589B (en)	1987-10-28	Process for preparing fluorinated phtaloyl- and terephtaloyl compounds
JP3907219B2 (ja)	2007-04-18	ｏ−クロロメチル安息香酸クロリドの製造方法
US3822311A (en)	1974-07-02	Process for the production of 2,5-dichloro-3-nitro-benzoic acid
US2753345A (en)	1956-07-03	Substituted mercaptobenzoic acids and methods of preparing the same
US2370015A (en)	1945-02-20	Derivatives of tertiary amino aliphatic acids
KR100217355B1 (ko)	1999-09-01	5-(3-부티릴-2,4,6-트리메틸)-2-(1-(에톡시이미노)프로필)-3-하이드록시싸이클로헥스-2-엔-1-온 제조방법
US3247224A (en)	1966-04-19	6h-[b, f] [1, 4, 5] dibenzo-oxathiazepins
US2654778A (en)	1953-10-06	Derivatives of cycloalkylbenzoylaralkanoic acids
US3743668A (en)	1973-07-03	Cyanoethylation of aminophenols
NO132930B (ja)	1975-10-27
US2688015A (en)	1954-08-31	Manufacture of sulfamerazine
ES2729404T3 (es)	2019-11-04	Proceso de hidrocloruro de fingolimod
US2339914A (en)	1944-01-25	Chemical compound
US2605267A (en)	1952-07-29	Beta-pyrrolidyl-ethyl esters of para-propoxybenzoic acid
US6548692B1 (en)	2003-04-15	Method for preparing 1,2-dibromo-2,4-dicyanobutane
SU1705281A1 (ru)	1992-01-15	Способ получени N-моноалкилзамещенных амидов ароматических сульфокислот
US3609168A (en)	1971-09-28	Thiadiazepines
CA1214470A (en)	1986-11-25	Process for the preparation of derivatives of 2- diethylamino-1-methyl ethyl cis-1-hydroxy- (bicyclohexyl)-2-carboxylate
SU595298A1 (ru)	1978-02-28	Способ получени гидрохлоридов алкилгидразинов
EP0650966A1 (de)	1995-05-03	Verfahren zur Herstellung eines Benzo(a)chinolizinon-Derivates

Legal Events

Date	Code	Title	Description
2002-11-04	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN SEPTEMBER 2002