NO306508B1 - Benzopyraner og beslektede LTB4 antagonister - Google Patents

Benzopyraner og beslektede LTB4 antagonister

Info

Publication number: NO306508B1
Authority: NO; Norway
Prior art keywords: benzopyrans; ltb4 antagonists; related ltb4; antagonists; ltb4
Prior art date: 1992-01-23

Application number

NO942759A

Other languages

English (en)

Norwegian (no)

Other versions

NO942759L (no

NO942759D0 (no

Inventor

Kevin Koch

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-23

Filing date

1994-07-22

Publication date

1999-11-15

1994-07-22 Application filed by Pfizer filed Critical Pfizer

1994-07-22 Publication of NO942759L publication Critical patent/NO942759L/no

1994-07-22 Publication of NO942759D0 publication Critical patent/NO942759D0/no

1999-11-15 Publication of NO306508B1 publication Critical patent/NO306508B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Furan Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

NO942759A 1992-01-23 1994-07-22 Benzopyraner og beslektede LTB4 antagonister NO306508B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US82441292A	1992-01-23	1992-01-23
PCT/US1992/009496 WO1993015067A1 (fr)	1992-01-23	1992-11-13	Benzopyranne et antagonistes de ltb4 apparentes

Publications (3)

Publication Number	Publication Date
NO942759L NO942759L (no)	1994-07-22
NO942759D0 NO942759D0 (no)	1994-07-22
NO306508B1 true NO306508B1 (no)	1999-11-15

Family

ID=25241346

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO942759A NO306508B1 (no)	1992-01-23	1994-07-22	Benzopyraner og beslektede LTB4 antagonister

Country Status (36)

Country	Link
US (2)	US5552435A (fr)
EP (1)	EP0623123B1 (fr)
JP (1)	JP2765757B2 (fr)
KR (2)	KR0124802B1 (fr)
CN (1)	CN1041311C (fr)
AP (1)	AP352A (fr)
AT (1)	ATE152108T1 (fr)
AU (1)	AU666896B2 (fr)
BG (1)	BG62331B1 (fr)
BR (1)	BR9207061A (fr)
CA (1)	CA2126752C (fr)
CZ (1)	CZ282400B6 (fr)
DE (1)	DE69219364T2 (fr)
DK (1)	DK0623123T3 (fr)
EG (1)	EG20202A (fr)
FI (1)	FI943474A7 (fr)
GR (1)	GR3023657T3 (fr)
HU (1)	HU221194B1 (fr)
IL (1)	IL104386A (fr)
IS (1)	IS1795B (fr)
MX (1)	MX9300312A (fr)
MY (1)	MY109144A (fr)
NO (1)	NO306508B1 (fr)
NZ (1)	NZ245735A (fr)
OA (1)	OA11456A (fr)
PH (1)	PH30346A (fr)
PL (1)	PL171003B1 (fr)
PT (1)	PT101183B (fr)
RO (1)	RO112031B1 (fr)
RU (1)	RU2114110C1 (fr)
SG (1)	SG49813A1 (fr)
SK (1)	SK280451B6 (fr)
TW (1)	TW213907B (fr)
WO (1)	WO1993015067A1 (fr)
YU (1)	YU48949B (fr)
ZA (1)	ZA93486B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2084547B1 (es) *	1993-07-12	1997-01-16	Pfizer	Antagonistas benzopiranicos y relacionados de leucotrieno b4.
EP0785930A1 (fr) *	1994-10-13	1997-07-30	Pfizer Inc.	Composes de benzopyranne et composes benzo-fusionnes, leur preparation et leur utilisation comme antagonistes de leucotriene b 4? (ltb 4?)
AU703557B2 (en) *	1994-10-13	1999-03-25	Pfizer Inc.	Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene B4' (LTB4) antagonists
US6096906A (en) *	1996-09-16	2000-08-01	Pfizer Inc.	Processes for preparing substituted chromanol derivatives
US6416733B1 (en)	1996-10-07	2002-07-09	Bristol-Myers Squibb Pharma Company	Radiopharmaceuticals for imaging infection and inflammation
EP0836850A3 (fr) *	1996-10-17	2000-11-29	Pfizer Inc.	Méthode pour prévenir le rejet d'allogreffes
EP0963755A3 (fr) *	1998-04-16	2001-03-14	Pfizer Products Inc.	Utilisation des benzopyranes pour la prévention de rejets de graiffes
US6436987B1 (en) *	2000-06-08	2002-08-20	Pfizer Inc.	Crystalline forms of (3S-trans)-2-[3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)-benzoic acid
CA2427911A1 (fr)	2000-11-03	2002-05-10	Bristol Myers Squibb Company	Double imagerie isotopique simultanee d'une perfusion et d'une inflammation cardiaque
MXPA03006876A (es) *	2001-01-30	2003-11-13	Pfizer Prod Inc	Intermedios y procedimientos para preparar derivados de cromanol sustituido.
AU4239302A (en) *	2001-06-28	2003-01-02	Pfizer Products Inc.	Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
AU2005266088A1 (en) *	2004-07-22	2006-02-02	Pharmacia Corporation	Compositions for treatment of inflammation and pain using a combination of a COX-2 selective inhibitor and a LTB4 receptor antagonist
EP3383389B1 (fr) *	2015-11-30	2021-04-28	Merck Sharp & Dohme Corp.	Utilisation d'arylacylsulfonamides en tant qu'antagonistes de blt1
WO2017095724A1 (fr)	2015-11-30	2017-06-08	Merck Sharp & Dohme Corp.	Sulfonamides d'aryle utilisés en tant qu'antagonistes de blt1
WO2017095722A1 (fr)	2015-11-30	2017-06-08	Merck Sharp & Dohme Corp.	Utilisation d'arylacylsulfonamides en tant qu'antagonistes de blt1
WO2017095725A1 (fr)	2015-11-30	2017-06-08	Merck Sharp & Dohme Corp.	Sulfonamides d'aryle utilisés en tant qu'antagonistes de blt1

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2309282A1 (de) *	1973-02-24	1974-08-29	Hoechst Ag	Verfahren zur herstellung von 4-hydroxy-thiochromanen
DE2745305A1 (de) *	1977-10-07	1979-04-19	Bayer Ag	Insektizide und akarizide mittel
US4565882A (en) *	1984-01-06	1986-01-21	G. D. Searle & Co.	Substituted dihydrobenzopyran-2-carboxylates
CA1320490C (fr) *	1987-01-12	1993-07-20	Darrel M. Gapinski	Agents antiinflammatoires
JPS63292977A (ja) *	1987-05-25	1988-11-30	片山　晋	スキ−用のビンディング固定板
MX13485A (es) *	1987-10-19	1993-05-01	Pfizer	Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
US5059609A (en) *	1987-10-19	1991-10-22	Pfizer Inc.	Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
US5298512A (en) *	1989-04-07	1994-03-29	Pfizer Inc.	Substituted chromans and their use in the treatment of asthma, arthritis and related diseases
WO1990015801A1 (fr) *	1989-06-22	1990-12-27	Pfizer Inc.	Sulfamides substitues et composes apparentes dans le traitement de l'asthme, de l'arthrite et des maladies apparentees
FI923546A7 (fi) *	1990-02-07	1992-08-06	Pfizer	Tetraliini- ja kromaanijohdannaisia, jotka ovat käyttökelpoisia astman ,niveltulehduksen ja vastaavien sairauksien hoidossa
BR9207064A (pt) *	1992-01-23	1995-12-19	Pfizer	Antagonistas de LTB4 à base de benzopiranos e relacionados
SG65570A1 (en) *	1992-02-25	1999-06-22	Recordati Chem Pharm	Heterobicyclic compounds
FR2693196B1 (fr) *	1992-07-03	1994-12-23	Lipha	Dérivés de benzopyranone ou de benzothiopyranone, procédé de préparation et composition pharmaceutique les contenant.

1992
- 1992-01-22 MX MX9300312A patent/MX9300312A/es not_active IP Right Cessation
- 1992-11-13 RU RU94035964/04A patent/RU2114110C1/ru not_active IP Right Cessation
- 1992-11-13 PL PL92304689A patent/PL171003B1/pl unknown
- 1992-11-13 DK DK92924284.0T patent/DK0623123T3/da active
- 1992-11-13 HU HU9401979A patent/HU221194B1/hu not_active IP Right Cessation
- 1992-11-13 CA CA002126752A patent/CA2126752C/fr not_active Expired - Lifetime
- 1992-11-13 BR BR9207061A patent/BR9207061A/pt not_active Application Discontinuation
- 1992-11-13 DE DE69219364T patent/DE69219364T2/de not_active Expired - Lifetime
- 1992-11-13 AT AT92924284T patent/ATE152108T1/de not_active IP Right Cessation
- 1992-11-13 KR KR1019940702518A patent/KR0124802B1/ko not_active Expired - Fee Related
- 1992-11-13 CZ CZ941762A patent/CZ282400B6/cs not_active IP Right Cessation
- 1992-11-13 RO RO94-01220A patent/RO112031B1/ro unknown
- 1992-11-13 FI FI943474A patent/FI943474A7/fi not_active IP Right Cessation
- 1992-11-13 WO PCT/US1992/009496 patent/WO1993015067A1/fr not_active Ceased
- 1992-11-13 EP EP92924284A patent/EP0623123B1/fr not_active Expired - Lifetime
- 1992-11-13 US US08/295,827 patent/US5552435A/en not_active Expired - Lifetime
- 1992-11-13 SK SK844-94A patent/SK280451B6/sk unknown
- 1992-11-13 SG SG1996006699A patent/SG49813A1/en unknown
- 1992-11-13 AU AU30650/92A patent/AU666896B2/en not_active Ceased
- 1992-11-13 JP JP5513184A patent/JP2765757B2/ja not_active Expired - Lifetime
- 1992-11-17 TW TW081109200A patent/TW213907B/zh active
- 1992-11-20 AP APAP/P/1992/000449A patent/AP352A/en active
1993
- 1993-01-02 EG EG3293A patent/EG20202A/xx active
- 1993-01-13 PH PH45558D patent/PH30346A/en unknown
- 1993-01-14 IL IL10438693A patent/IL104386A/en not_active IP Right Cessation
- 1993-01-19 MY MYPI93000086A patent/MY109144A/en unknown
- 1993-01-19 IS IS3969A patent/IS1795B/is unknown
- 1993-01-21 CN CN93100769A patent/CN1041311C/zh not_active Expired - Fee Related
- 1993-01-22 YU YU3393A patent/YU48949B/sh unknown
- 1993-01-22 ZA ZA93486A patent/ZA93486B/xx unknown
- 1993-01-22 NZ NZ245735A patent/NZ245735A/en unknown
- 1993-01-22 PT PT101183A patent/PT101183B/pt not_active IP Right Cessation
1994
- 1994-06-21 BG BG98867A patent/BG62331B1/bg unknown
- 1994-07-22 NO NO942759A patent/NO306508B1/no not_active IP Right Cessation
- 1994-07-22 KR KR1019940702518A patent/KR950700273A/ko active Granted
- 1994-07-22 OA OA60543A patent/OA11456A/en unknown
1996
- 1996-05-03 US US08/642,711 patent/US5684046A/en not_active Expired - Lifetime
1997
- 1997-06-04 GR GR970401301T patent/GR3023657T3/el unknown

Also Published As

Publication number	Publication date
TW213907B (fr)	1993-10-01
BG62331B1 (bg)	1999-08-31
PT101183B (pt)	1999-09-30
PL171003B1 (pl)	1997-02-28
OA11456A (en)	2003-11-18
MX9300312A (es)	1993-07-31
FI943474L (fi)	1994-07-22
KR950700273A (ko)	1995-01-16
PT101183A (pt)	1994-03-31
NZ245735A (en)	1995-04-27
FI943474A0 (fi)	1994-07-22
RO112031B1 (ro)	1997-04-30
JP2765757B2 (ja)	1998-06-18
AU666896B2 (en)	1996-02-29
HK1000245A1 (en)	1998-02-13
NO942759L (no)	1994-07-22
FI943474A7 (fi)	1994-07-22
DE69219364T2 (de)	1997-08-07
CN1075318A (zh)	1993-08-18
CZ176294A3 (en)	1995-02-15
YU48949B (sh)	2003-01-31
JPH07502536A (ja)	1995-03-16
RU2114110C1 (ru)	1998-06-27
IS3969A (is)	1993-07-24
AU3065092A (en)	1993-09-01
ZA93486B (en)	1994-07-22
AP9200449A0 (en)	1993-01-31
NO942759D0 (no)	1994-07-22
RU94035964A (ru)	1997-05-27
CA2126752C (fr)	2000-05-16
BR9207061A (pt)	1995-12-26
CA2126752A1 (fr)	1993-08-05
EP0623123A1 (fr)	1994-11-09
HUT68790A (en)	1995-07-28
DE69219364D1 (de)	1997-05-28
CZ282400B6 (cs)	1997-07-16
EG20202A (en)	1997-10-30
SK280451B6 (sk)	2000-02-14
AP352A (en)	1994-08-10
IL104386A (en)	2001-05-20
EP0623123B1 (fr)	1997-04-23
HU9401979D0 (en)	1994-09-28
SG49813A1 (en)	1998-06-15
CN1041311C (zh)	1998-12-23
KR0124802B1 (ko)	1997-11-25
ATE152108T1 (de)	1997-05-15
US5684046A (en)	1997-11-04
MY109144A (en)	1996-12-31
IL104386A0 (en)	1993-05-13
IS1795B (is)	2001-12-18
HU221194B1 (en)	2002-08-28
YU3393A (sh)	1996-07-24
BG98867A (bg)	1995-03-31
PH30346A (en)	1997-04-02
WO1993015067A1 (fr)	1993-08-05
DK0623123T3 (da)	1997-10-13
SK84494A3 (en)	1995-05-10
US5552435A (en)	1996-09-03
GR3023657T3 (en)	1997-09-30

Publication	Publication Date	Title
NO942758D0 (no)	1994-07-22	Benzopyraner og beslektede LTB4 antagonister
DE59208263D1 (de)	1997-04-30	3-Aryl-4-hydroxy-delta3-dihydrofuranon- und 3-Aryl-4-hydroxy-delta3-dihydrothiophenon-Derivate
NO961425D0 (no)	1996-04-11	1N-alkyl-N-arylpyrimidinaminer og derivater derav
FI944624A7 (fi)	1995-04-08	4-aryyliaminobentsopyraani- ja niiden kaltaisia yhdisteitä
NO942759L (no)	1994-07-22	Benzopyraner og beslektede LTB4 antagonister
FI910116L (fi)	1992-07-10	sigma-delta-modulator foer d/a-omvandlare
FI933201L (fi)	1994-01-17	Vaerme- och kylvals
NO922934D0 (no)	1992-07-23	Cykloheksan- og tetrahydropyranderivater
FI933019L (fi)	1994-01-02	Bensotiazepin- och bensoxatzepinderivat
BR9205281A (pt)	1993-07-27	Pentapeptideos imuno-reguladores e neuro-reguladores
FI1031U1 (fi)	1993-11-19	En troakar
ITMI921571A1 (it)	1993-12-26	Azaciclo e azabiciclo alchiliden idrossilamine
NO305649B1 (no)	1999-07-05	Silot°mmeanordning
ZA93483B (en)	1994-07-22	Benzopyrans and related ltb antagonists
KR940007037U (ko)	1994-04-12	캔 온장고
ES1022279Y (es)	1993-08-01	Muneca
ATE149330T1 (de)	1997-03-15	Handgelenkorthese
KR930002787U (ko)	1993-02-25	구축용 조립블록

Legal Events

Date	Code	Title	Description
2004-11-22	MM1K	Lapsed by not paying the annual fees