NO20082133L - Immunoglobulin-fusjonsproteinformuleringer - Google Patents
Immunoglobulin-fusjonsproteinformuleringerInfo
- Publication number
- NO20082133L NO20082133L NO20082133A NO20082133A NO20082133L NO 20082133 L NO20082133 L NO 20082133L NO 20082133 A NO20082133 A NO 20082133A NO 20082133 A NO20082133 A NO 20082133A NO 20082133 L NO20082133 L NO 20082133L
- Authority
- NO
- Norway
- Prior art keywords
- fusion protein
- compositions
- immunoglobulin fusion
- protein formulations
- lyophilized
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 102000037865 fusion proteins Human genes 0.000 title abstract 4
- 108020001507 fusion proteins Proteins 0.000 title abstract 4
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 238000001816 cooling Methods 0.000 abstract 1
- 150000002016 disaccharides Chemical class 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73927105P | 2005-11-22 | 2005-11-22 | |
| PCT/US2006/045059 WO2007062040A1 (fr) | 2005-11-22 | 2006-11-21 | Preparations a base de proteines hybrides d'immunoglobuline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082133L true NO20082133L (no) | 2008-06-16 |
Family
ID=37781927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082133A NO20082133L (no) | 2005-11-22 | 2008-05-07 | Immunoglobulin-fusjonsproteinformuleringer |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20070237758A1 (fr) |
| EP (1) | EP1951305A1 (fr) |
| JP (1) | JP2009516692A (fr) |
| KR (1) | KR20080071192A (fr) |
| CN (1) | CN101312744A (fr) |
| AU (1) | AU2006318583A1 (fr) |
| BR (1) | BRPI0618893A2 (fr) |
| CA (1) | CA2630115A1 (fr) |
| CR (1) | CR10012A (fr) |
| EC (1) | ECSP088459A (fr) |
| NO (1) | NO20082133L (fr) |
| RU (1) | RU2008118166A (fr) |
| SV (1) | SV2009002911A (fr) |
| WO (1) | WO2007062040A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2390354T3 (es) * | 2005-07-22 | 2012-11-12 | Amgen, Inc | Liofilizados de proteínas concentrados, procedimientos y usos |
| BRPI0806313A2 (pt) * | 2007-01-09 | 2011-09-06 | Wyeth Corp | Formulação de anticorpo anti-il-13; formulação em aerossol de um anticorpo anti-il-13; formulaçãoliofilizada de um anticorpo anti-il-13; composição farmacêutica para o tratamento de um transtorno relacionado a il-13; fabricação de uma composição farmacêutica ; método de tratamento de um transtorno relacionado a il-13; seringa injetável; dispositivo para administração nasal; emplastro transdérmico; bolsa intravenosa; kit compreendendo pelo menos um recipiente; kit; e seringa injetável previamente enchida |
| CA2677937A1 (fr) * | 2007-02-16 | 2008-08-21 | Wyeth | Utilisation de saccharose pour supprimer une agregation de proteines provoquee par du mannitol |
| JP5469077B2 (ja) * | 2007-11-12 | 2014-04-09 | アレス トレーディング ソシエテ アノニム | Taci−免疫グロブリン融合タンパク質のための調製物 |
| JO3672B1 (ar) | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| AR076284A1 (es) | 2009-04-29 | 2011-06-01 | Bayer Schering Pharma Ag | Inmunoconjugados de antimesotelina y usos de los mismos |
| CN102695499A (zh) * | 2009-06-18 | 2012-09-26 | 惠氏有限责任公司 | 小模块免疫药物的冻干制剂 |
| CN101693016B (zh) * | 2009-11-02 | 2012-07-25 | 北京美福源生物医药科技有限公司 | 通用的注射用重组人血清白蛋白融合蛋白制剂配方 |
| AU2010315325B2 (en) | 2009-11-03 | 2014-11-27 | Grifols Therapeutics Inc. | Composition, method, and kit for alpha-1 proteinase inhibitor |
| AU2010324839B2 (en) * | 2009-11-24 | 2015-02-19 | Grifols Therapeutics Inc. | Lyophilization methods, compositions, and kits |
| JO3417B1 (ar) | 2010-01-08 | 2019-10-20 | Regeneron Pharma | الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r |
| AU2012210481B2 (en) | 2011-01-28 | 2017-05-18 | Sanofi Biotechnology | Pharmaceutical compositions comprising human antibodies to PCSK9 |
| AR087305A1 (es) | 2011-07-28 | 2014-03-12 | Regeneron Pharma | Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit |
| TWI589299B (zh) | 2011-10-11 | 2017-07-01 | 再生元醫藥公司 | 用於治療類風濕性關節炎之組成物及其使用方法 |
| CN104940926B (zh) | 2014-09-25 | 2017-09-22 | 信达生物制药(苏州)有限公司 | 重组融合蛋白制剂 |
| CN105435222B (zh) | 2014-09-25 | 2018-05-29 | 信达生物制药(苏州)有限公司 | 重组融合蛋白制剂 |
| GB201513010D0 (en) * | 2015-07-23 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel formulation |
| JP2018523684A (ja) | 2015-08-18 | 2018-08-23 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | リポタンパク質アフェレーシスを受けている高脂血症の患者を治療するための抗pcsk9阻害抗体 |
| CA3099551C (fr) | 2018-05-10 | 2025-08-19 | Regeneron Pharma | Formulations contenant des proteines de fusion du recepteur vegf a haute concentration |
| WO2020021330A2 (fr) * | 2018-07-12 | 2020-01-30 | Endo Global Aesthetics Limited | Techniques d'injection pour le traitement de la cellulite |
| CN118267895A (zh) * | 2018-10-30 | 2024-07-02 | 中国科学院化学研究所 | 一种制备药物或药物中间体无定型物的方法 |
| CN111195349B (zh) * | 2018-11-16 | 2023-02-24 | 鲁南制药集团股份有限公司 | 一种代谢调节融合蛋白的冻干粉制剂 |
| WO2020142701A1 (fr) * | 2019-01-06 | 2020-07-09 | Endo Global Aesthetics Limited | Formulations de collagénase et leurs procédés de production |
| KR20210122810A (ko) | 2019-01-31 | 2021-10-12 | 사노피 바이오테크놀로지 | 청소년 특발성 관절염을 치료하기 위한 항 il-6 수용체 항체 |
| SG11202108627SA (en) | 2019-02-18 | 2021-09-29 | Lilly Co Eli | Therapeutic antibody formulation |
| CN114651010A (zh) | 2019-04-24 | 2022-06-21 | 赛诺菲生物技术公司 | 类风湿性关节炎的诊断和治疗方法 |
| EP3980459A1 (fr) | 2019-06-04 | 2022-04-13 | Sanofi Biotechnology | Compositions et procédés de traitement de la douleur chez des sujets atteints de polyarthrite rhumatoïde |
| CN113125489A (zh) * | 2019-12-31 | 2021-07-16 | 上海药明生物技术有限公司 | 生物制剂配方优化和工艺优化的方法和系统 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4597966A (en) * | 1985-01-09 | 1986-07-01 | Ortho Diagnostic Systems, Inc. | Histidine stabilized immunoglobulin and method of preparation |
| US5843707A (en) * | 1992-10-23 | 1998-12-01 | Genetics Institute, Inc. | Nucleic acid encoding a novel P-selectin ligand protein |
| US6372716B1 (en) * | 1994-04-26 | 2002-04-16 | Genetics Institute, Inc. | Formulations for factor IX |
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| EP1516628B1 (fr) * | 1995-07-27 | 2013-08-21 | Genentech, Inc. | Formulation de protéine stabile, lyophilisée et isotonique |
| US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| JP3900664B2 (ja) * | 1997-09-26 | 2007-04-04 | 株式会社ニコン | 顕微鏡 |
| US7198789B2 (en) * | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| CZ300547B6 (cs) * | 1999-02-22 | 2009-06-10 | University Of Connecticut | Nové formulace faktoru VIII prosté albuminu |
| WO2000066160A1 (fr) * | 1999-04-28 | 2000-11-09 | Yamanouchi Pharmaceutical Co., Ltd. | Composition medicamenteuse parenterale a fragment d'anticorps monoclonal humanise et procede de stabilisation |
| ATE402716T1 (de) * | 2002-02-27 | 2008-08-15 | Immunex Corp | Stabilisierte tnfr-fc formulierung mit arginin |
| CA2554018A1 (fr) * | 2004-03-04 | 2005-09-29 | Wyeth | Procede de lyophilisation permettant d'ameliorer la cristallisation de l'excipient |
-
2006
- 2006-11-21 KR KR1020087015109A patent/KR20080071192A/ko not_active Withdrawn
- 2006-11-21 US US11/562,299 patent/US20070237758A1/en not_active Abandoned
- 2006-11-21 AU AU2006318583A patent/AU2006318583A1/en not_active Abandoned
- 2006-11-21 RU RU2008118166/15A patent/RU2008118166A/ru not_active Application Discontinuation
- 2006-11-21 EP EP06838185A patent/EP1951305A1/fr not_active Withdrawn
- 2006-11-21 CA CA002630115A patent/CA2630115A1/fr not_active Abandoned
- 2006-11-21 JP JP2008541422A patent/JP2009516692A/ja not_active Withdrawn
- 2006-11-21 CN CNA2006800437873A patent/CN101312744A/zh active Pending
- 2006-11-21 WO PCT/US2006/045059 patent/WO2007062040A1/fr not_active Ceased
- 2006-11-21 BR BRPI0618893-1A patent/BRPI0618893A2/pt not_active IP Right Cessation
-
2008
- 2008-05-07 NO NO20082133A patent/NO20082133L/no not_active Application Discontinuation
- 2008-05-19 EC EC2008008459A patent/ECSP088459A/es unknown
- 2008-05-22 SV SV2008002911A patent/SV2009002911A/es unknown
- 2008-05-22 CR CR10012A patent/CR10012A/es not_active Application Discontinuation
-
2010
- 2010-10-22 US US12/910,146 patent/US20110033464A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080071192A (ko) | 2008-08-01 |
| EP1951305A1 (fr) | 2008-08-06 |
| RU2008118166A (ru) | 2009-12-27 |
| AU2006318583A1 (en) | 2007-05-31 |
| ECSP088459A (es) | 2008-06-30 |
| US20070237758A1 (en) | 2007-10-11 |
| SV2009002911A (es) | 2009-03-04 |
| US20110033464A1 (en) | 2011-02-10 |
| CN101312744A (zh) | 2008-11-26 |
| CA2630115A1 (fr) | 2007-05-31 |
| JP2009516692A (ja) | 2009-04-23 |
| BRPI0618893A2 (pt) | 2011-09-13 |
| CR10012A (es) | 2008-07-29 |
| WO2007062040A1 (fr) | 2007-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |