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NO20080359L - Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base - Google Patents

Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base

Info

Publication number
NO20080359L
NO20080359L NO20080359A NO20080359A NO20080359L NO 20080359 L NO20080359 L NO 20080359L NO 20080359 A NO20080359 A NO 20080359A NO 20080359 A NO20080359 A NO 20080359A NO 20080359 L NO20080359 L NO 20080359L
Authority
NO
Norway
Prior art keywords
escitalopram
base
salts
crystalline
oxalate
Prior art date
Application number
NO20080359A
Other languages
English (en)
Norwegian (no)
Inventor
Hans Petersen
Ole Nielsen
Michael Harold Rock
Robert Dancer
Helle Eliasen
Ken Lijegren
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20080359(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20080359L publication Critical patent/NO20080359L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20080359A 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base NO20080359L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500912 2005-06-22
PCT/DK2006/000366 WO2006136169A2 (fr) 2005-06-22 2006-06-22 Base cristalline d'escitalopram et comprimes orodispersible la comprenant

Publications (1)

Publication Number Publication Date
NO20080359L true NO20080359L (no) 2008-01-18

Family

ID=37546630

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20080359A NO20080359L (no) 2005-06-22 2008-01-18 Krystallinsk base av escitalopram og orodispergerbare tabletter omfattende escitalopram base
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20101777A NO20101777L (no) 2005-06-22 2010-12-20 Orodispergerbare tabletter

Country Status (39)

Country Link
EP (3) EP2325177A1 (fr)
JP (5) JP4906852B2 (fr)
KR (5) KR20120064140A (fr)
CN (2) CN101189220A (fr)
AR (2) AR055062A1 (fr)
AT (3) ATE497500T1 (fr)
AU (2) AU2006261452B2 (fr)
BG (1) BG66086B1 (fr)
BR (1) BRPI0612295A2 (fr)
CA (2) CA2646780A1 (fr)
CY (1) CY1112392T1 (fr)
CZ (3) CZ300686B6 (fr)
DE (2) DE112006001619T5 (fr)
DK (3) DK1896439T4 (fr)
EA (2) EA201001108A1 (fr)
EE (1) EE00773U1 (fr)
ES (2) ES2319073B1 (fr)
FI (2) FI20080548A7 (fr)
GB (2) GB2442160B (fr)
HR (1) HRP20110093T4 (fr)
HU (1) HUP0800135A3 (fr)
IL (1) IL187454A0 (fr)
IS (1) IS8705A (fr)
LT (1) LT5550B (fr)
LV (1) LV13677B (fr)
MX (1) MX2007015328A (fr)
MY (2) MY143252A (fr)
NO (2) NO20080359L (fr)
PL (2) PL1896439T5 (fr)
PT (1) PT1896439E (fr)
RS (1) RS51575B2 (fr)
SG (1) SG169358A1 (fr)
SI (1) SI1896439T2 (fr)
SK (1) SK500402007A3 (fr)
TR (2) TR201000625T1 (fr)
TW (2) TWI347942B (fr)
UA (1) UA86536C2 (fr)
WO (1) WO2006136169A2 (fr)
ZA (2) ZA200711066B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
WO2008059514A2 (fr) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Procédé de préparation d'escitalopram
WO2008104880A2 (fr) * 2007-03-01 2008-09-04 Aurobindo Pharma Limited Formes posologiques solides stables d'un antidépresseur
DK2595979T3 (en) 2010-07-23 2016-05-17 Lundbeck & Co As H A process for the purification of pharmaceutically acceptable salts of escitalopram
CN103360353A (zh) * 2013-08-07 2013-10-23 中国药科大学 草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN110711198B (zh) * 2018-07-12 2022-03-15 山东大学 D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko) 2019-04-09 2021-11-26 주식회사 라이트팜텍 에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법
EP4277661A1 (fr) * 2021-01-18 2023-11-22 Anton Frenkel Forme posologique pharmaceutique

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* Cited by examiner, † Cited by third party
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GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JPH05222041A (ja) * 1992-02-13 1993-08-31 Mitsubishi Gas Chem Co Inc アデニン誘導体の精製法
EP0743850B1 (fr) * 1994-01-27 1999-10-06 The Board Of Regents Of The University Of Oklahoma Forme de dosage orale a dissolution rapide
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
EP0993524B1 (fr) 1997-06-30 2002-11-20 Beloit Technologies, Inc. Procede et dispositif pour l'application a vitesse elevee d'une sauce de couchage sur une bande de papier en mouvement
EA001728B1 (ru) 1997-07-08 2001-08-27 Х.Лундбекк А/С Способ получения циталопрама
ES2149734T3 (es) 1997-11-11 2003-02-16 Lundbeck & Co As H Metodo para la preparacion de citalopram.
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
EP1329217A4 (fr) * 2000-10-06 2007-04-04 Takeda Pharmaceutical Preparations solides
CA2426682C (fr) * 2000-10-16 2010-02-16 Daiichi Pharmaceutical Co., Ltd. Compositions medicinales intra-buccales a desintegration rapide et procede pour leur production
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
HK1048812B (zh) * 2000-12-22 2007-06-01 H‧隆德贝克有限公司 制备纯西酞普兰的方法
EA003459B1 (ru) * 2000-12-28 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама
US20040198809A1 (en) * 2001-05-01 2004-10-07 Connie Sanchez Use of enantiomeric pure escitalopram
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
DK1522539T3 (da) * 2001-07-31 2007-05-07 Lundbeck & Co As H Krystallinsk komposition indeholdende excitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) * 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP2228060A1 (fr) * 2002-05-03 2010-09-15 Skyepharma Canada Inc. Formes galéniques orales comportant du fénofibrate
EA013116B1 (ru) 2002-12-23 2010-02-26 Х. Лундбекк А/С Эсциталопрамгидробромид, его применение и фармкомпозиция
CN1510024A (zh) * 2002-12-24 2004-07-07 北京德众万全药物技术开发有限公司 可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
EP1620075B1 (fr) * 2003-05-07 2020-06-24 Samyang Biopharmaceuticals Corporation Granules a teneur elevee en plastique, destines a la fabrication de comprimes a dissolution rapide
WO2005037254A1 (fr) * 2003-10-15 2005-04-28 Fuji Chemical Industry Co., Ltd. Comprime se desintegrant rapidement dans la cavite buccale
WO2005049596A1 (fr) * 2003-11-20 2005-06-02 Natco Pharma Limited Procede de preparation d'escitalopram de haute purete
HU227491B1 (en) * 2003-11-25 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Tablet containing citalopram hydrogen bromide
CA2558198A1 (fr) * 2004-03-05 2005-09-15 H. Lundbeck A/S Composition cristalline contenant de l'oxalate d'escitalopram
WO2006106531A1 (fr) * 2005-04-04 2006-10-12 Jubilant Organosys Ltd Processus de preparation d'escitalopram ou de ses sels d'addition acides

Also Published As

Publication number Publication date
KR20120064140A (ko) 2012-06-18
GB0724557D0 (en) 2008-01-23
SG169358A1 (en) 2011-03-30
AU2006261452A1 (en) 2006-12-28
IS8705A (is) 2008-01-14
TR200708792T1 (tr) 2008-05-21
CA2612827A1 (fr) 2006-12-28
FI20077133A7 (fi) 2007-12-20
JP2012072168A (ja) 2012-04-12
BRPI0612295A2 (pt) 2011-01-04
GB2442160A (en) 2008-03-26
TW200740785A (en) 2007-11-01
ZA200711066B (en) 2009-07-29
DK200800075A (da) 2008-03-15
ES2356838T5 (es) 2015-01-26
BG66086B1 (bg) 2011-03-31
UA86536C2 (ru) 2009-04-27
HRP20110093T4 (hr) 2015-02-27
JP2008546724A (ja) 2008-12-25
ES2319073A1 (es) 2009-05-01
DK200900284A (da) 2009-02-27
EP1896439B1 (fr) 2011-02-02
RS51575B2 (sr) 2018-02-28
CZ300686B6 (cs) 2009-07-15
PL384185A1 (pl) 2008-06-23
BG110024A (bg) 2008-05-30
SK500402007A3 (sk) 2008-05-06
CN101928269A (zh) 2010-12-29
JP4415056B2 (ja) 2010-02-17
WO2006136169A2 (fr) 2006-12-28
AR055062A1 (es) 2007-08-01
KR20110084341A (ko) 2011-07-21
EA019239B1 (ru) 2014-02-28
HUP0800135A3 (en) 2009-01-28
JP4906852B2 (ja) 2012-03-28
SI1896439T2 (sl) 2014-12-31
EP1896439A2 (fr) 2008-03-12
GB2448834A (en) 2008-10-29
AR079750A2 (es) 2012-02-15
HUP0800135A2 (en) 2008-06-30
IL187454A0 (en) 2008-02-09
JP2009046506A (ja) 2009-03-05
CN101189220A (zh) 2008-05-28
TWI358407B (en) 2012-02-21
FI20080548L (fi) 2008-10-07
PT1896439E (pt) 2011-02-15
PL1896439T3 (pl) 2011-04-29
ZA200901698B (en) 2010-04-28
KR20080018191A (ko) 2008-02-27
HRP20110093T1 (hr) 2011-03-31
AT10983U1 (de) 2010-02-15
LV13677B (en) 2008-05-20
MX2007015328A (es) 2008-02-15
DE112006001619T5 (de) 2008-06-12
DK1896439T4 (en) 2015-01-12
LT5550B (lt) 2009-03-25
LT2008005A (en) 2008-10-27
DE602006019961D1 (de) 2011-03-17
DK1896439T3 (da) 2011-02-28
AU2006261452B2 (en) 2010-02-04
GB0811164D0 (en) 2008-07-23
KR20100133023A (ko) 2010-12-20
SI1896439T1 (sl) 2011-03-31
PL1896439T5 (pl) 2016-01-29
WO2006136169A3 (fr) 2007-10-18
CZ299906B6 (cs) 2008-12-29
TWI347942B (en) 2011-09-01
CA2646780A1 (fr) 2006-12-28
AU2010200844A1 (en) 2010-04-01
MY143252A (en) 2011-04-15
EE00773U1 (et) 2008-10-15
FI20080548A7 (fi) 2008-10-07
ES2319073B1 (es) 2010-02-26
EA201001108A1 (ru) 2011-02-28
RS51575B (en) 2011-08-31
JP5731957B2 (ja) 2015-06-10
JP2009179635A (ja) 2009-08-13
MY143239A (en) 2011-04-15
EP2325177A1 (fr) 2011-05-25
GB2448834B (en) 2010-01-20
CA2612827C (fr) 2010-11-30
ES2356838T3 (es) 2011-04-13
ATE497500T1 (de) 2011-02-15
TR201000625T1 (tr) 2010-03-22
EA200800102A1 (ru) 2008-04-28
GB2442160B (en) 2010-01-20
CY1112392T1 (el) 2015-12-09
KR20110033310A (ko) 2011-03-30
TW201130808A (en) 2011-09-16
JP2009179634A (ja) 2009-08-13
AT11883U1 (de) 2011-06-15
CZ301286B6 (cs) 2009-12-30
EP2385044A1 (fr) 2011-11-09
EP1896439B2 (fr) 2014-10-15
FI20077133L (fi) 2007-12-20
KR101340815B1 (ko) 2013-12-11
NO20101777L (no) 2008-01-18
CZ2007898A3 (cs) 2008-01-23

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