NO20071609L - Immunogen sammensetning for anvendelse ved vaksinering mot stafylokokker - Google Patents
Immunogen sammensetning for anvendelse ved vaksinering mot stafylokokkerInfo
- Publication number
- NO20071609L NO20071609L NO20071609A NO20071609A NO20071609L NO 20071609 L NO20071609 L NO 20071609L NO 20071609 A NO20071609 A NO 20071609A NO 20071609 A NO20071609 A NO 20071609A NO 20071609 L NO20071609 L NO 20071609L
- Authority
- NO
- Norway
- Prior art keywords
- staphylococcal
- protein
- immunogenic composition
- vaccination against
- against staphylococci
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000002163 immunogen Effects 0.000 title abstract 2
- 241000295644 Staphylococcaceae Species 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 230000001018 virulence Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/116—Polyvalent bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0421082A GB0421082D0 (en) | 2004-09-22 | 2004-09-22 | Immunogenic composition |
| GB0421079A GB0421079D0 (en) | 2004-09-22 | 2004-09-22 | Immunogenic composition |
| GB0421078A GB0421078D0 (en) | 2004-09-22 | 2004-09-22 | Immunogenic composition |
| GB0421081A GB0421081D0 (en) | 2004-09-22 | 2004-09-22 | Immunogenic composition |
| GB0503143A GB0503143D0 (en) | 2005-02-15 | 2005-02-15 | Immunogenic composition |
| PCT/EP2005/010184 WO2006032472A2 (fr) | 2004-09-22 | 2005-09-20 | Composition immunogene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20071609L true NO20071609L (no) | 2007-06-18 |
Family
ID=36000843
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071609A NO20071609L (no) | 2004-09-22 | 2007-03-27 | Immunogen sammensetning for anvendelse ved vaksinering mot stafylokokker |
| NO20071610A NO20071610L (no) | 2004-09-22 | 2007-03-27 | Immunogen sammensetning |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20071610A NO20071610L (no) | 2004-09-22 | 2007-03-27 | Immunogen sammensetning |
Country Status (17)
| Country | Link |
|---|---|
| US (6) | US20080095777A1 (fr) |
| EP (9) | EP1804833A2 (fr) |
| JP (5) | JP2008513409A (fr) |
| KR (4) | KR101508563B1 (fr) |
| CN (2) | CN101128215B (fr) |
| AU (3) | AU2005287505A1 (fr) |
| BR (3) | BRPI0515520A (fr) |
| CA (4) | CA2584290A1 (fr) |
| ES (4) | ES2540771T3 (fr) |
| IL (4) | IL181825A0 (fr) |
| MA (2) | MA28994B1 (fr) |
| MX (2) | MX2007003402A (fr) |
| NO (2) | NO20071609L (fr) |
| NZ (4) | NZ582441A (fr) |
| RU (1) | RU2402347C2 (fr) |
| WO (3) | WO2006032472A2 (fr) |
| ZA (1) | ZA200702224B (fr) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL229487B1 (pl) | 2002-11-12 | 2018-07-31 | Brigham & Womens Hospital Inc | Kompozycja zawierająca polimer β-1,6-glukozaminy, kompozycja zawierająca przeciwciało, kompozycja farmaceutyczna, sposób wytwarzania wyodrębnionego polisacharydu, sposób identyfikacji obecności deacetylowanej poli-N-acetyloglukozaminy (dPNAG) i/ lub poli-N-acetyloglukozaminy (PNAG), wyodrębniony polisacharyd do zastosowania w leczeniu lub profilaktyce zakażenia, wyodrębniony polisacharyd do zastosowania do wytwarzania przeciwciał, w tym przeciwciał monoklonalnych, wyodrębniony polisacharyd do zastosowania w identyfikacji przeciwciała monoklonalnego |
| ES2540771T3 (es) * | 2004-09-22 | 2015-07-13 | Glaxosmithkline Biologicals Sa | Composición de anticuerpos para uso en vacunación contra estafilococos |
| EP2213298A3 (fr) | 2004-10-21 | 2011-07-20 | Wyeth LLC | Composition immunogène de staphylococcus epidermidis polypeptide et polynucleotide antigènes |
| EP1812066A4 (fr) * | 2004-10-25 | 2010-06-30 | Univ Western Ontario | Anti-infectieux a base de proteine isd pour une infection a staphylococcus aureus |
| US20060228368A1 (en) * | 2005-04-07 | 2006-10-12 | Nabi Biopharmaceuticals | Method of protecting against staphylococcal infection |
| JP5297800B2 (ja) * | 2005-06-27 | 2013-09-25 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| GB0526038D0 (en) * | 2005-12-21 | 2006-02-01 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US20090317421A1 (en) * | 2006-01-18 | 2009-12-24 | Dominique Missiakas | Compositions and methods related to staphylococcal bacterium proteins |
| US20100021503A1 (en) * | 2006-03-30 | 2010-01-28 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| CN101432440B (zh) * | 2006-04-24 | 2013-08-21 | 西格马食品可变资本有限公司 | 通过实时聚合酶链反应检测和多重、同时量化病原体的方法 |
| GB0610776D0 (en) * | 2006-05-31 | 2006-07-12 | Univ Bath | Novel applications for staphylococcus aureus Sbi protein |
| US20180221466A9 (en) * | 2006-06-12 | 2018-08-09 | Glaxosmithkline Biologicals S.A. | Use of alpha-toxin for treating and preventing staphylococcus infections |
| CN102743747A (zh) * | 2006-06-12 | 2012-10-24 | 葛兰素史密斯克蓝生物品公司 | α-毒素在治疗和预防葡萄球菌感染上的用途 |
| GB0700136D0 (en) * | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
| EP2374467B1 (fr) * | 2007-05-04 | 2013-08-28 | Martin Krönke | Vaccin de protection contre le staphylococcus aureus basé sur des protéines liées à la paroi cellulaire |
| US8146781B2 (en) * | 2007-08-09 | 2012-04-03 | Huhtamaki, Inc. | Dispenser for viscous condiments |
| WO2009023164A2 (fr) * | 2007-08-10 | 2009-02-19 | President And Fellows Of Harvard College | Induction de l'immunité des muqueuses |
| WO2009029831A1 (fr) * | 2007-08-31 | 2009-03-05 | University Of Chicago | Procédés et compositions associées pour immuniser contre des maladies et des états staphylococciques des poumons |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| CN102015651B (zh) | 2008-03-03 | 2014-12-31 | Irm责任有限公司 | 作为tlr活性调节剂的化合物和组合物 |
| US8241857B2 (en) * | 2008-03-31 | 2012-08-14 | Otsuka Pharmaceutical Co., Ltd. | Method for detection of pneumococcus |
| WO2009127677A1 (fr) * | 2008-04-16 | 2009-10-22 | Glaxosmithkline Biologicals S.A. | Vaccin |
| TWI551295B (zh) * | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
| EP3312158A1 (fr) | 2008-07-21 | 2018-04-25 | The Brigham and Women's Hospital, Inc. | Procédés et compositions se rapportant à des bêta-1,6-glucosamine oligosaccharides synthétiques |
| US8758765B2 (en) | 2008-07-29 | 2014-06-24 | The University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
| WO2010039563A2 (fr) * | 2008-09-30 | 2010-04-08 | University Of Maryland, Baltimore | Vaccin protecteur contre des biofilms de staphylococcus aureus renfermant des immunogènes associés à la paroi cellulaire |
| EP2208787A1 (fr) * | 2009-01-19 | 2010-07-21 | Université de Liège | Polypeptide d'alpha-hémolysine recombinant de Staphylococcus aureus doté d'une suppression dans le domaine de la branche et des insertions de séquences hétérologues |
| US8101190B2 (en) * | 2009-03-03 | 2012-01-24 | Ingen Biosciences | Method for diagnosing staphylococcal infections |
| WO2011005341A2 (fr) | 2009-04-03 | 2011-01-13 | University Of Chicago | Compositions et méthodes associées aux variants de la protéine a (spa) |
| TR201802380T4 (tr) | 2009-06-10 | 2018-03-21 | Glaxosmithkline Biologicals Sa | Benzonaftiridin içeren aşılar. |
| NZ597191A (en) * | 2009-06-22 | 2013-11-29 | Wyeth Llc | Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions |
| JP5395264B2 (ja) | 2009-06-22 | 2014-01-22 | ワイス・エルエルシー | 黄色ブドウ球菌(staphylococcusaureus)抗原の免疫原性組成物 |
| WO2012122533A2 (fr) * | 2011-03-10 | 2012-09-13 | The University Of Chicago | Compositions et procédés liés à des anticorps contre les protéines staphylococciques isda ou isdb |
| US8647621B2 (en) | 2009-07-27 | 2014-02-11 | Fina Biosolutions, Llc | Method of producing protein-carbohydrate vaccines reduced in free carbohydrate |
| GB0913681D0 (en) * | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| BR112012004806B8 (pt) | 2009-09-02 | 2022-10-04 | Novartis Ag | composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| AU2010352695B2 (en) | 2009-09-30 | 2014-08-21 | Glaxosmithkline Biologicals S.A. | Conjugation of Staphylococcus aureus type 5 and type 8 capsular polysaccharides |
| LT2493498T (lt) | 2009-10-30 | 2017-05-25 | Glaxosmithkline Biologicals Sa | Staphylococcus aureus 5 tipo ir 8 tipo kapsulinių sacharidų gryninimas |
| WO2011057148A1 (fr) | 2009-11-05 | 2011-05-12 | Irm Llc | Composés et compositions permettant de moduler l'activité des tlr-7 |
| CA2781049A1 (fr) * | 2009-11-16 | 2011-05-19 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine , Inc. | Vaccin bacterien contre les gram positifs a base de (poly)glycerolphosphate |
| SG181712A1 (en) | 2009-12-15 | 2012-07-30 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| SG10201506162RA (en) | 2009-12-17 | 2015-09-29 | Fina Biosolutions Llc | Chemical reagents for the activation of polysaccharides in the preparation of conjugate vaccines |
| MX341395B (es) | 2010-03-23 | 2016-08-18 | Novartis Ag * | Compuestos (lipopeptidos basados en cisteina) y composiciones como agonistas de tlr2 usados para el tratamiento de infecciones, inflamaciones, enfermedades respiratorias, etc. |
| EP2555794A4 (fr) | 2010-04-05 | 2014-01-15 | Univ Chicago | COMPOSITIONS ET PROCÉDÉS LIÉS AUX ANTICORPS DE LA PROTÉINE A (SpA) EN TANT QUE AMPLIFICATEUR DE LA RÉPONSE IMMUNITAIRE |
| WO2011133191A1 (fr) | 2010-04-23 | 2011-10-27 | Serum Institute Of India, Ltd. | Méthode simple d'élimination simultanée de nombreuses impuretés à partir de surnageants de culture jusqu'à des niveaux ultra-faibles |
| CN102268444B (zh) * | 2010-06-03 | 2015-05-13 | 中国人民解放军军事医学科学院生物工程研究所 | 金黄色葡萄球菌截短SasA蛋白在大肠杆菌中的表达及应用 |
| JP6002128B2 (ja) | 2010-07-02 | 2016-10-05 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | プロテインA(SpA)変種に関連する組成物および方法 |
| US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| EP2593134A4 (fr) * | 2010-07-15 | 2014-05-21 | Merck Sharp & Dohme | Vaccin protecteur basés sur la protéine staphylococcus aureus sa2412 |
| JP5793194B2 (ja) | 2010-09-09 | 2015-10-14 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 感染防御ブドウ球菌抗原が関与する方法および組成物 |
| WO2012065034A1 (fr) * | 2010-11-12 | 2012-05-18 | Merck Sharp & Dohme Corp. | Vaccins à base de conjugués de peptide énolase, contre staphylococcus aureus |
| RU2570730C2 (ru) * | 2010-12-22 | 2015-12-10 | УАЙТ ЭлЭлСи | Стабильные иммуногенные композиции антигенов staphylococcus aureus |
| ES2709065T7 (es) * | 2011-02-08 | 2021-12-09 | Medimmune Llc | Anticuerpos que se unen específicamente a la toxina alfa de Staphylococcus aureus y métodos de uso |
| CA2825770A1 (fr) * | 2011-02-08 | 2012-08-16 | Integrated Biotherapeutics, Inc. | Composition immunogene comprenant des oligopeptides d'alpha-hemolysine |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| MY165115A (en) | 2011-06-19 | 2018-02-28 | Univ New York | Leukotoxin e/d as a new anti-inflammatory agent and microbicide |
| BR112013032774B1 (pt) | 2011-06-19 | 2020-05-05 | Univ New York | composições compreendendo proteína luke isolada ou polipeptídeo da mesma, uma proteína lukd isolada ou polipeptídeo da mesma ou sua combinação, bem como seu uso |
| JP6317670B2 (ja) | 2011-08-15 | 2018-04-25 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌プロテインaに対する抗体に関連した組成物および方法 |
| US9527892B2 (en) | 2011-10-31 | 2016-12-27 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2451 protein |
| CN102698260B (zh) * | 2012-04-20 | 2013-09-25 | 西北农林科技大学 | 预防山羊葡萄球菌乳房炎的亚单位疫苗的制备方法及应用 |
| CA2910320A1 (fr) | 2012-04-26 | 2013-10-31 | University Of Chicago | Compositions et procedes associes a des anticorps qui neutralisent l'activite coagulase dans une maladie a staphylococcus aureus |
| US9968668B2 (en) | 2012-04-26 | 2018-05-15 | The University Of Chicago | Staphylococcal coagulase antigens and methods of their use |
| RU2646102C2 (ru) * | 2012-05-09 | 2018-03-01 | Контрафект Корпорейшн | Предотвращение, разрушение и обработка биопленки лизином бактериофага |
| WO2013184900A2 (fr) * | 2012-06-06 | 2013-12-12 | Sanofi Pasteur Biologics, Llc | Compositions immunogènes et procédés associés |
| EP2872173A4 (fr) | 2012-07-10 | 2016-03-23 | Merck Sharp & Dohme | Vaccin protecteur à base de protéine sa2493 de staphylococcus aureus |
| CN102993308B (zh) * | 2012-09-29 | 2014-11-05 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌(mrsa)疫苗重组蛋白抗原hi2及制备方法和应用 |
| CN102898511B (zh) * | 2012-10-19 | 2014-05-07 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌重组基因工程疫苗候选抗原i12c制备中的纯化方法 |
| CN103087198B (zh) * | 2013-01-21 | 2014-03-12 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌(mrsa)疫苗重组蛋白抗原i1c及制备方法和应用 |
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| CN103333254A (zh) * | 2013-06-21 | 2013-10-02 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌(mrsa)重组蛋白疫苗i1c的纯化方法 |
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