NO20065038L - Anvendelse. - Google Patents
Anvendelse.Info
- Publication number
- NO20065038L NO20065038L NO20065038A NO20065038A NO20065038L NO 20065038 L NO20065038 L NO 20065038L NO 20065038 A NO20065038 A NO 20065038A NO 20065038 A NO20065038 A NO 20065038A NO 20065038 L NO20065038 L NO 20065038L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- isomer
- energy balance
- negative energy
- ruminants
- Prior art date
Links
- 241000282849 Ruminantia Species 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000007976 Ketosis Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 230000004140 ketosis Effects 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 230000000069 prophylactic effect Effects 0.000 abstract 2
- 208000011580 syndromic disease Diseases 0.000 abstract 2
- 208000004930 Fatty Liver Diseases 0.000 abstract 1
- 206010019708 Hepatic steatosis Diseases 0.000 abstract 1
- 206010046793 Uterine inflammation Diseases 0.000 abstract 1
- 210000001015 abdomen Anatomy 0.000 abstract 1
- 230000036528 appetite Effects 0.000 abstract 1
- 235000019789 appetite Nutrition 0.000 abstract 1
- 238000009109 curative therapy Methods 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 208000010515 dystocia Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000010706 fatty liver disease Diseases 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
- 210000002826 placenta Anatomy 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det beskrives anvendelse av en forbindelse av formel (I): en isomer derav, et prodrug av nevnte forbindelse eller isomer, eller et farmasøytisk akseptabelt salt av nevnte forbindelse, isomer eller prodrug, for fremstilling av et medikament for lindrende, profylaktisk eller helbredende virkning på negativ energibalanse i drøvtyggere. Anvendelse av en forbindelse av formel (I) for fremstilling av et medikament for lindrende, profylaktisk eller helbredende behandling av drøv-tyggersykdom assosiert med negativ energibalanse i drøvtyggere, hvor drøvtyggersykdommen assosiert med negativ energibalanse er valgt blant fettleversyndrom, dystocia, immundysfunksjon, svekket immunfunksjon, toksifisering, primær ketose, sekundær ketose, downer kusyndrom, dårlig fordøyelighet, manglende appetitt, svekket placenta, forskjøvet løypemage, mastitt, (endo-)-metritis, infertilitet, lav fertilitet og uførhet. (I) Hvor V, Y, F, G, A, W, E, X, m og n er som definert i krav 1.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57417104P | 2004-05-25 | 2004-05-25 | |
| PCT/IB2005/001438 WO2005115389A2 (en) | 2004-05-25 | 2005-05-13 | Specific ppar agonists for treating negative energy balance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20065038L true NO20065038L (no) | 2006-12-01 |
Family
ID=34967765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20065038A NO20065038L (no) | 2004-05-25 | 2006-11-02 | Anvendelse. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070281935A1 (no) |
| EP (1) | EP1753426A2 (no) |
| JP (1) | JP2008500323A (no) |
| CN (1) | CN1956719A (no) |
| AR (1) | AR049185A1 (no) |
| AU (1) | AU2005247164B2 (no) |
| BR (1) | BRPI0511481A (no) |
| CA (1) | CA2567398A1 (no) |
| IL (1) | IL179244A0 (no) |
| MX (1) | MXPA06013754A (no) |
| NO (1) | NO20065038L (no) |
| RU (1) | RU2353362C2 (no) |
| TW (1) | TWI280879B (no) |
| WO (1) | WO2005115389A2 (no) |
| ZA (1) | ZA200609235B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0511613A (pt) * | 2004-05-25 | 2008-01-02 | Pfizer Prod Inc | uso de agonista de ppar |
| GB0510141D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B3 |
| US8133901B2 (en) * | 2006-12-01 | 2012-03-13 | Actelion Pharmaceuticals Ltd. | 3-heteroaryl (amino or amido)-1-(biphenyl or phenylthiazolyl) carbonylpiperidine derivatives as orexin receptor inhibitors |
| GB0722769D0 (en) * | 2007-11-21 | 2008-01-02 | Biolipox Ab | New compounds |
| JP2010521444A (ja) * | 2007-03-12 | 2010-06-24 | バイオリポックス エービー | 炎症の治療において有用なピペリジノン類 |
| CA2745643C (en) * | 2008-12-02 | 2015-12-01 | Danisco A/S | A bacillus pumilus strain and methods for improving ruminant health and performance |
| DE102009038123A1 (de) | 2009-08-17 | 2011-02-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiazolyl-carbonyl)imidazolidinone und ihre Verwendung |
| WO2011114103A1 (en) | 2010-03-18 | 2011-09-22 | Biolipox Ab | Pyrimidinones for use as medicaments |
| GB201314286D0 (en) | 2013-08-08 | 2013-09-25 | Takeda Pharmaceutical | Therapeutic Compounds |
| CN116162056A (zh) * | 2021-11-24 | 2023-05-26 | 上海医药工业研究院 | β-catenin/BCL9蛋白-蛋白相互作用的小分子抑制剂及其应用 |
| WO2024145931A1 (zh) * | 2023-01-06 | 2024-07-11 | 上海医药工业研究院有限公司 | β-catenin/BCL9蛋白蛋白相互作用的小分子抑制剂及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2340734A1 (fr) * | 1976-02-13 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de la m-trifluoromethylphenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
| US5854211A (en) * | 1993-12-23 | 1998-12-29 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
| DE10238865A1 (de) * | 2002-08-24 | 2004-03-11 | Boehringer Ingelheim International Gmbh | Neue Carbonsäureamid-Verbindungen mit MCH-antagonistischer Wirkung, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| CN100439337C (zh) * | 2002-11-26 | 2008-12-03 | 辉瑞产品公司 | 作为ppar活化剂的苯基取代的哌啶化合物 |
| GEP20084393B (en) * | 2003-04-24 | 2008-06-10 | Incyte Corp | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| BRPI0511613A (pt) * | 2004-05-25 | 2008-01-02 | Pfizer Prod Inc | uso de agonista de ppar |
-
2005
- 2005-05-13 RU RU2006141628/15A patent/RU2353362C2/ru not_active IP Right Cessation
- 2005-05-13 WO PCT/IB2005/001438 patent/WO2005115389A2/en not_active Ceased
- 2005-05-13 JP JP2007514167A patent/JP2008500323A/ja active Pending
- 2005-05-13 US US11/569,513 patent/US20070281935A1/en not_active Abandoned
- 2005-05-13 CA CA002567398A patent/CA2567398A1/en not_active Abandoned
- 2005-05-13 CN CNA2005800167704A patent/CN1956719A/zh active Pending
- 2005-05-13 EP EP05738586A patent/EP1753426A2/en not_active Withdrawn
- 2005-05-13 MX MXPA06013754A patent/MXPA06013754A/es unknown
- 2005-05-13 BR BRPI0511481-0A patent/BRPI0511481A/pt not_active IP Right Cessation
- 2005-05-13 AU AU2005247164A patent/AU2005247164B2/en not_active Ceased
- 2005-05-20 TW TW094116567A patent/TWI280879B/zh not_active IP Right Cessation
- 2005-05-23 AR ARP050102112A patent/AR049185A1/es not_active Application Discontinuation
-
2006
- 2006-11-02 NO NO20065038A patent/NO20065038L/no not_active Application Discontinuation
- 2006-11-06 ZA ZA200609235A patent/ZA200609235B/xx unknown
- 2006-11-13 IL IL179244A patent/IL179244A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL179244A0 (en) | 2007-03-08 |
| WO2005115389A2 (en) | 2005-12-08 |
| CA2567398A1 (en) | 2005-12-08 |
| AU2005247164B2 (en) | 2008-11-27 |
| RU2006141628A (ru) | 2008-05-27 |
| ZA200609235B (en) | 2008-08-27 |
| AU2005247164A1 (en) | 2005-12-08 |
| MXPA06013754A (es) | 2007-02-08 |
| EP1753426A2 (en) | 2007-02-21 |
| RU2353362C2 (ru) | 2009-04-27 |
| JP2008500323A (ja) | 2008-01-10 |
| WO2005115389A3 (en) | 2006-11-16 |
| AR049185A1 (es) | 2006-07-05 |
| CN1956719A (zh) | 2007-05-02 |
| BRPI0511481A (pt) | 2007-12-26 |
| TWI280879B (en) | 2007-05-11 |
| US20070281935A1 (en) | 2007-12-06 |
| TW200607501A (en) | 2006-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |