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NO20065722L - Medisinske aerosolformuleringsprodukter med forbedret kjemisk stabilitet. - Google Patents

Medisinske aerosolformuleringsprodukter med forbedret kjemisk stabilitet.

Info

Publication number
NO20065722L
NO20065722L NO20065722A NO20065722A NO20065722L NO 20065722 L NO20065722 L NO 20065722L NO 20065722 A NO20065722 A NO 20065722A NO 20065722 A NO20065722 A NO 20065722A NO 20065722 L NO20065722 L NO 20065722L
Authority
NO
Norway
Prior art keywords
aerosol formulation
chemical stability
improved chemical
linking agent
butyl rubber
Prior art date
Application number
NO20065722A
Other languages
English (en)
Inventor
David Lewis
Brian John Meakin
Tanya Kathleen Church
Robert Johnson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of NO20065722L publication Critical patent/NO20065722L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Medisinsk produkt i form av aerosolformulering med forbedret kjemisk stabilitet, omfattende en trykksatt inhalator som gir utmålt dose, som omfatter en aerosolkanister utstyrt med en doseringsventil anordnet med forseglingsringer og/eller pakninger fremstilt av et vulkanisat av et elastomer materiale av en butylgummi, et tverrbindingsmiddel for butylgummien og en akselerator for tverrbindingsmidlet, hvor akseleratoren innbefatter en polysulfidforbindelse avledet fra en substituert ditiokarbonsyre eller et derivat av denne, hvor den trykksatte inhalator som gir utmålt dose inneholder i aerosolkanisteren en medisinsk aerosolformulering som inneholder en langtidsvirkende P2-agonist, et hydrogenfluorkarbondrivmiddel, et ko-løsningsmiddel og en mineralsyre som stabilisator for den aktive bestanddel.
NO20065722A 2004-05-13 2006-12-12 Medisinske aerosolformuleringsprodukter med forbedret kjemisk stabilitet. NO20065722L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04011425 2004-05-13
PCT/EP2005/002041 WO2005112902A2 (en) 2004-05-13 2005-02-25 Medicinal aerosol formulation products with improved chemical stability

Publications (1)

Publication Number Publication Date
NO20065722L true NO20065722L (no) 2006-12-12

Family

ID=34960892

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065722A NO20065722L (no) 2004-05-13 2006-12-12 Medisinske aerosolformuleringsprodukter med forbedret kjemisk stabilitet.

Country Status (19)

Country Link
US (1) US20070086953A1 (no)
EP (1) EP1746981B1 (no)
JP (1) JP2007537170A (no)
KR (1) KR20070010159A (no)
CN (1) CN1950075A (no)
AT (1) ATE404185T1 (no)
AU (1) AU2005245248A1 (no)
BR (1) BRPI0510852A (no)
CA (1) CA2565747A1 (no)
DE (1) DE602005008946D1 (no)
EA (1) EA200602112A1 (no)
ES (1) ES2309722T3 (no)
IL (1) IL178739A0 (no)
MA (1) MA28649B1 (no)
MX (1) MXPA06013189A (no)
NO (1) NO20065722L (no)
TN (1) TNSN06334A1 (no)
WO (1) WO2005112902A2 (no)
ZA (1) ZA200608742B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3089735T1 (sl) * 2013-12-30 2018-10-30 Chiesi Farmaceutici S.P.A. Sestavek stabilne aerosolne raztopine pod tlakom, ki vsebuje glikopironijev bromid in formoterol
ES2666905T4 (es) * 2013-12-30 2018-06-07 Chiesi Farmaceutici S.P.A. Composición en solución para aerosol estable presurizada de una combinación de bromuro de glicopirronio y formoterol
CN106620976B (zh) * 2016-12-28 2020-01-07 四川普锐特医药科技有限责任公司 一种丙酸氟替卡松定量吸入气雾剂
GB202001537D0 (en) 2020-02-05 2020-03-18 Consort Medical Plc Pressurised dispensing container
CA3193038A1 (en) * 2020-10-09 2022-04-14 Enrico Zambelli A pharmaceutical formulation for pressurised metered dose inhaler

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0015884A (pt) * 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
KR100947409B1 (ko) * 2002-03-01 2010-03-12 키에시 파르마슈티시 엣스. 피. 에이. 포모테롤 초미세 조성물
US20040126325A1 (en) * 2002-03-12 2004-07-01 David Lewis Medicinal aerosol solution formulation products with improved chemical stability
US7736712B2 (en) * 2002-03-18 2010-06-15 Consort Medical Plc Seal material for a dispensing apparatus
KR20070000476A (ko) * 2004-02-27 2007-01-02 키에시 파르마슈티시 엣스. 피. 에이. 압축화 계량된 도스흡입용 안정된 약제용액 제제
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
EP1850831B1 (en) * 2005-02-25 2015-12-02 CHIESI FARMACEUTICI S.p.A. Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

Also Published As

Publication number Publication date
IL178739A0 (en) 2007-02-11
AU2005245248A1 (en) 2005-12-01
ES2309722T3 (es) 2008-12-16
CA2565747A1 (en) 2005-12-01
WO2005112902A3 (en) 2006-05-04
CN1950075A (zh) 2007-04-18
WO2005112902A2 (en) 2005-12-01
KR20070010159A (ko) 2007-01-22
DE602005008946D1 (de) 2008-09-25
TNSN06334A1 (en) 2008-02-22
MA28649B1 (fr) 2007-06-01
BRPI0510852A (pt) 2007-11-27
ATE404185T1 (de) 2008-08-15
MXPA06013189A (es) 2007-02-14
US20070086953A1 (en) 2007-04-19
EP1746981B1 (en) 2008-08-13
EA200602112A1 (ru) 2007-04-27
EP1746981A2 (en) 2007-01-31
ZA200608742B (en) 2008-07-30
JP2007537170A (ja) 2007-12-20

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application