NO20050904L - 13-leddete azalider og deres anvendelse som antibiotiske midler - Google Patents

13-leddete azalider og deres anvendelse som antibiotiske midler

Info

Publication number: NO20050904L
Authority: NO; Norway
Prior art keywords: antibiotics; membered azalides; azalides; membered
Prior art date: 1998-11-20

Application number

NO20050904A

Other languages

English (en)

Other versions

NO329629B1 (no

Inventor

Barry James Morton

John Philip Dirlam

Robert John Rafka

Colman Brendan Ragan

Peter Bertinato

Alan Elwood Blize

Carl Bernard Ziegler

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-20

Filing date

2005-02-18

Publication date

2001-07-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22327457&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20050904(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-07-17 Publication of NO20050904L publication Critical patent/NO20050904L/no

2005-02-18 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2010-11-22 Publication of NO329629B1 publication Critical patent/NO329629B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Biotechnology (AREA)
Public Health (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicinal Preparation (AREA)
Pyrane Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20050904A 1998-11-20 2005-02-18 13-leddete azalider NO329629B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10939998P	1998-11-20	1998-11-20
PCT/IB1999/001803 WO2000031097A1 (en)	1998-11-20	1999-11-09	13-membered azalides and their use as antibiotic agents

Publications (2)

Publication Number	Publication Date
NO20050904L true NO20050904L (no)	2001-07-17
NO329629B1 NO329629B1 (no)	2010-11-22

Family

ID=22327457

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
NO20012464A NO319796B1 (no)	1998-11-20	1999-11-09	13-leddete azalider, fremgangsmåte for fremstilling og anvendelse derav samt farmasøytisk sammensetning.
NO20050904A NO329629B1 (no)	1998-11-20	2005-02-18	13-leddete azalider
NO20050893A NO330249B1 (no)	1998-11-20	2005-02-18	Azalider samt anvendelser og fremstilling derav, og farmasøytiske sammensetninger

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
NO20012464A NO319796B1 (no)	1998-11-20	1999-11-09	13-leddete azalider, fremgangsmåte for fremstilling og anvendelse derav samt farmasøytisk sammensetning.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20050893A NO330249B1 (no)	1998-11-20	2005-02-18	Azalider samt anvendelser og fremstilling derav, og farmasøytiske sammensetninger

Country Status (46)

Country	Link
US (1)	US6329345B1 (no)
EP (1)	EP1131331B1 (no)
JP (1)	JP3842973B2 (no)
KR (1)	KR100477774B1 (no)
CN (2)	CN1326460A (no)
AP (1)	AP2001002142A0 (no)
AR (3)	AR019496A1 (no)
AT (1)	ATE260927T1 (no)
AU (1)	AU766106B2 (no)
BG (1)	BG65107B1 (no)
BR (2)	BRPI9915480B8 (no)
CA (1)	CA2351429C (no)
CO (1)	CO5380019A1 (no)
CZ (1)	CZ303099B6 (no)
DE (1)	DE69915336T2 (no)
DK (1)	DK1131331T3 (no)
DZ (1)	DZ2944A1 (no)
EA (2)	EA009729B1 (no)
EG (1)	EG23823A (no)
ES (1)	ES2216581T3 (no)
GT (1)	GT199900198A (no)
HK (1)	HK1041269A1 (no)
HR (1)	HRP20010374B1 (no)
HU (1)	HU229008B1 (no)
ID (1)	ID28548A (no)
IL (3)	IL142631A0 (no)
IS (1)	IS2350B (no)
MA (1)	MA26707A1 (no)
ME (1)	ME00467B (no)
MY (1)	MY122353A (no)
NO (3)	NO319796B1 (no)
NZ (1)	NZ511199A (no)
OA (1)	OA11713A (no)
PA (1)	PA8485601A1 (no)
PE (1)	PE20001378A1 (no)
PL (1)	PL198580B1 (no)
PT (1)	PT1131331E (no)
RS (1)	RS50302B (no)
SI (1)	SI1131331T1 (no)
SK (1)	SK284607B6 (no)
TN (1)	TNSN99214A1 (no)
TW (2)	TWI243825B (no)
UA (1)	UA70972C2 (no)
UY (1)	UY25805A1 (no)
WO (1)	WO2000031097A1 (no)
ZA (1)	ZA200104019B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HN1998000086A (es)	1997-06-11	1999-03-08	Pfizer Prod Inc	Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
AP9801420A0 (en) *	1998-01-02	1998-12-31	Pfizer Prod Inc	Novel macrolides.
UA70972C2 (uk) *	1998-11-20	2004-11-15	Пфайзер Продактс Інк.	13-членні азаліди і їх застосування як антибіотиків
KR20020016799A (ko) *	1999-05-24	2002-03-06	데이비드 존 우드	13-메틸-에리트로마이신 유도체
US6465437B1 (en) *	1999-06-30	2002-10-15	Pfizer Inc.	Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
OA12257A (en) *	2000-04-27	2003-11-06	Pfizer Prod Inc	the use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals.
BR0209241A (pt) *	2001-04-27	2004-06-15	Pfizer Prod Inc	Processo para preparação de derivados de9-deoxo-9a-aza-9a-homoeritromicina a 4-substituida
WO2003014136A1 (en) *	2001-08-08	2003-02-20	Taisho Pharmaceutical Co., Ltd.	11a-AZALIDE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
CA2529817C (en) *	2003-03-10	2013-02-12	Optimer Pharmaceuticals, Inc.	Novel antibacterial agents
WO2004108744A2 (en) *	2003-05-19	2004-12-16	Prasad K Deshpande	Azalides and azaketolides having antimicrobial activity
RU2322241C2 (ru) *	2003-11-21	2008-04-20	Пфайзер Продактс Инк.	Применение антибиотиков в качестве адъювантов вакцин
EP1985620A4 (en) *	2006-02-07	2012-08-15	Taisho Pharmaceutical Co Ltd	COMPOUND 10a-AZALIDE
US8293715B2 (en)	2007-08-06	2012-10-23	Taisho Pharmaceutical Co., Ltd.	10a-Azalide compound crosslinked at 10a- and 12-positions
US8299035B2 (en)	2008-05-15	2012-10-30	Taisho Pharmaceutucal Co., Ltd.	10a-azalide compound having 4-membered ring structure
EP2619214B1 (en) *	2010-09-20	2014-12-24	Novartis AG	Novel process for the preparation of 9-deoxo-9a-aza-9a-homoerythromycin a modified in the c-4'' of the cladinose ring by an epoxide group
CN102295672B (zh) *	2011-07-13	2014-06-04	武汉回盛生物科技有限公司	一种泰拉菌素的合成方法
EP2736915A1 (en)	2011-07-27	2014-06-04	Farma GRS, d.o.o.	New crystalline forms of tulathromycin
CN102786569B (zh) *	2012-09-07	2016-12-07	安徽中升药业有限公司	泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
EP3027634B1 (en) *	2013-07-31	2018-03-21	Farma GRS, d.o.o.	Process for preparation of tulathromycin
CN109748942A (zh) *	2014-05-16	2019-05-14	普莱柯生物工程股份有限公司	一种大环内酯类化合物
CN104725446B (zh) *	2015-03-26	2017-10-27	宁夏泰瑞制药股份有限公司	一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
SG11202105227QA (en) *	2018-11-19	2021-06-29	Zikani Therapeutics Inc	C10-alkylene substituted 13-membered macrolides and uses thereof
AU2019385383B2 (en) *	2018-11-19	2023-06-15	President And Fellows Of Harvard College	C10-Cyclic Substituted 13-Membered Macrolides and Uses Thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU43116B (en)	1979-04-02	1989-04-30	Pliva Pharm & Chem Works	Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
YU43006B (en) *	1981-03-06	1989-02-28	Pliva Pharm & Chem Works	Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) *	1982-07-19	1984-10-02	Pfizer Inc.	N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
SI8611592A8 (en) *	1986-09-12	1995-04-30	Pliva Pharm & Chem Works	Process for preparing complexes of N-methyl-11-aza-10-deoxo-10-dihydroeritromicine A and 11-aza-10-deoxo-10-dihydroeritromicine A with metals
US5106961A (en)	1987-05-26	1992-04-21	Eli Lilly And Company	Erythromycin ring-contracted derivatives
SI9011409A (en)	1990-07-18	1995-10-31	Pliva Pharm & Chem Works	O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
HRP931480B1 (en) *	1993-12-08	1997-08-31	Sour Pliva	9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
GB2327084A (en) *	1997-07-08	1999-01-13	Merck & Co Inc	9a-Aza-3-ketolide antibiotics
UA70972C2 (uk) *	1998-11-20	2004-11-15	Пфайзер Продактс Інк.	13-членні азаліди і їх застосування як антибіотиків

1999
- 1999-09-11 UA UA2001053376A patent/UA70972C2/uk unknown
- 1999-11-09 AU AU10686/00A patent/AU766106B2/en not_active Expired
- 1999-11-09 CN CN99813464A patent/CN1326460A/zh active Pending
- 1999-11-09 NO NO20012464A patent/NO319796B1/no not_active IP Right Cessation
- 1999-11-09 RS YUP-334/01A patent/RS50302B/sr unknown
- 1999-11-09 PL PL347784A patent/PL198580B1/pl unknown
- 1999-11-09 DE DE1999615336 patent/DE69915336T2/de not_active Expired - Lifetime
- 1999-11-09 ID IDW00200101093A patent/ID28548A/id unknown
- 1999-11-09 EA EA200400701A patent/EA009729B1/ru not_active IP Right Cessation
- 1999-11-09 IL IL14263199A patent/IL142631A0/xx unknown
- 1999-11-09 AP APAP/P/2001/002142A patent/AP2001002142A0/en unknown
- 1999-11-09 EA EA200100416A patent/EA005156B1/ru not_active IP Right Cessation
- 1999-11-09 NZ NZ511199A patent/NZ511199A/en not_active IP Right Cessation
- 1999-11-09 DK DK99954277T patent/DK1131331T3/da active
- 1999-11-09 JP JP2000583925A patent/JP3842973B2/ja not_active Expired - Lifetime
- 1999-11-09 AT AT99954277T patent/ATE260927T1/de active
- 1999-11-09 CA CA002351429A patent/CA2351429C/en not_active Expired - Lifetime
- 1999-11-09 HK HK02102807.7A patent/HK1041269A1/zh unknown
- 1999-11-09 HU HU0104313A patent/HU229008B1/hu active Protection Beyond IP Right Term
- 1999-11-09 BR BRPI9915480A patent/BRPI9915480B8/pt not_active IP Right Cessation
- 1999-11-09 ES ES99954277T patent/ES2216581T3/es not_active Expired - Lifetime
- 1999-11-09 CN CNA2008100813586A patent/CN101367853A/zh active Pending
- 1999-11-09 SI SI9930572T patent/SI1131331T1/xx unknown
- 1999-11-09 KR KR10-2001-7006301A patent/KR100477774B1/ko not_active Expired - Lifetime
- 1999-11-09 EP EP99954277A patent/EP1131331B1/en not_active Expired - Lifetime
- 1999-11-09 PT PT99954277T patent/PT1131331E/pt unknown
- 1999-11-09 OA OA1200100120A patent/OA11713A/en unknown
- 1999-11-09 CZ CZ20011754A patent/CZ303099B6/cs not_active IP Right Cessation
- 1999-11-09 HR HR20010374A patent/HRP20010374B1/xx not_active IP Right Cessation
- 1999-11-09 ME MEP-2008-719A patent/ME00467B/me unknown
- 1999-11-09 WO PCT/IB1999/001803 patent/WO2000031097A1/en not_active Ceased
- 1999-11-09 SK SK663-2001A patent/SK284607B6/sk not_active IP Right Cessation
- 1999-11-09 BR BRPI9915480A patent/BRPI9915480B1/pt not_active IP Right Cessation
- 1999-11-15 TW TW092131563A patent/TWI243825B/zh not_active IP Right Cessation
- 1999-11-15 TW TW088119885A patent/TWI243824B/zh not_active IP Right Cessation
- 1999-11-17 PA PA19998485601A patent/PA8485601A1/es unknown
- 1999-11-17 TN TNTNSN99214A patent/TNSN99214A1/fr unknown
- 1999-11-17 EG EG147699A patent/EG23823A/xx active
- 1999-11-17 DZ DZ990244A patent/DZ2944A1/xx active
- 1999-11-17 MA MA25850A patent/MA26707A1/fr unknown
- 1999-11-17 UY UY25805A patent/UY25805A1/es not_active Application Discontinuation
- 1999-11-18 MY MYPI99005021A patent/MY122353A/en unknown
- 1999-11-18 GT GT199900198A patent/GT199900198A/es unknown
- 1999-11-18 AR ARP990105876A patent/AR019496A1/es active IP Right Grant
- 1999-11-18 US US09/442,530 patent/US6329345B1/en not_active Expired - Lifetime
- 1999-11-18 PE PE1999001166A patent/PE20001378A1/es not_active Application Discontinuation
- 1999-11-18 CO CO99072704A patent/CO5380019A1/es active IP Right Grant
2001
- 2001-04-16 IL IL142631A patent/IL142631A/en not_active IP Right Cessation
- 2001-04-17 IS IS5918A patent/IS2350B/is unknown
- 2001-05-17 ZA ZA200104019A patent/ZA200104019B/en unknown
- 2001-06-14 BG BG105600A patent/BG65107B1/bg unknown
2005
- 2005-02-18 NO NO20050904A patent/NO329629B1/no not_active IP Right Cessation
- 2005-02-18 NO NO20050893A patent/NO330249B1/no not_active IP Right Cessation
2007
- 2007-02-15 AR ARP070100662A patent/AR059523A2/es active IP Right Grant
- 2007-02-15 AR ARP070100663A patent/AR059524A2/es active IP Right Grant
2008
- 2008-02-11 IL IL189430A patent/IL189430A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE260927T1 (de)	2004-03-15
OA11713A (en)	2005-01-25
IS2350B (is)	2008-04-15
PL198580B1 (pl)	2008-06-30
IL189430A0 (en)	2008-06-05
CA2351429C (en)	2005-07-12
ME00467B (me)	2011-10-10
AR019496A1 (es)	2002-02-20
YU33401A (sh)	2004-05-12
HK1041269A1 (zh)	2002-07-05
EG23823A (en)	2007-09-19
HUP0104313A3 (en)	2003-12-29
CZ20011754A3 (cs)	2002-03-13
CZ303099B6 (cs)	2012-04-04
DZ2944A1 (fr)	2004-03-15
DE69915336T2 (de)	2005-01-13
EA009729B1 (ru)	2008-02-28
PE20001378A1 (es)	2000-12-14
NO319796B1 (no)	2005-09-19
SK6632001A3 (en)	2002-07-02
BRPI9915480B1 (pt)	2015-12-29
CN1326460A (zh)	2001-12-12
AU766106B2 (en)	2003-10-09
HRP20010374A2 (en)	2002-06-30
TWI243825B (en)	2005-11-21
EA005156B1 (ru)	2004-12-30
ID28548A (id)	2001-05-31
IS5918A (is)	2001-04-17
PA8485601A1 (es)	2000-09-29
CO5380019A1 (es)	2004-03-31
RS50302B (sr)	2009-09-08
NO20012464D0 (no)	2001-05-18
WO2000031097A1 (en)	2000-06-02
MY122353A (en)	2006-04-29
UA70972C2 (uk)	2004-11-15
NO330249B1 (no)	2011-03-14
NO329629B1 (no)	2010-11-22
JP3842973B2 (ja)	2006-11-08
NO20050893L (no)	2001-07-17
BG65107B1 (bg)	2007-02-28
GT199900198A (es)	2001-05-11
ZA200104019B (en)	2002-06-17
EA200400701A1 (ru)	2004-12-30
KR20010086043A (ko)	2001-09-07
EA200100416A1 (ru)	2001-10-22
AR059524A2 (es)	2008-04-09
DE69915336D1 (de)	2004-04-08
NO20012464L (no)	2001-07-17
HRP20010374B1 (en)	2006-09-30
BRPI9915480B8 (pt)	2022-05-10
IL142631A (en)	2010-05-31
IL189430A (en)	2010-05-31
AP2001002142A0 (en)	2001-05-09
JP2002530422A (ja)	2002-09-17
IL142631A0 (en)	2002-03-10
EP1131331B1 (en)	2004-03-03
MA26707A1 (fr)	2004-12-20
TW200404077A (en)	2004-03-16
BR9915480A (pt)	2001-07-31
NZ511199A (en)	2003-08-29
TNSN99214A1 (fr)	2005-11-10
PT1131331E (pt)	2004-06-30
DK1131331T3 (da)	2004-06-14
ES2216581T3 (es)	2004-10-16
HU229008B1 (en)	2013-07-29
TWI243824B (en)	2005-11-21
AR059523A2 (es)	2008-04-09
SK284607B6 (sk)	2005-07-01
SI1131331T1 (en)	2004-08-31
CN101367853A (zh)	2009-02-18
EP1131331A1 (en)	2001-09-12
BG105600A (en)	2001-12-29
AU1068600A (en)	2000-06-13
US6329345B1 (en)	2001-12-11
HUP0104313A2 (hu)	2002-02-28
KR100477774B1 (ko)	2005-03-21
CA2351429A1 (en)	2000-06-02
PL347784A1 (en)	2002-04-22
UY25805A1 (es)	2001-08-27

Publication	Publication Date	Title
DK1131331T3 (da)	2004-06-14	13-leddede azalider og deres anvendelse som antibiotiske midler
NO20021253L (no)	2002-04-24	Kinolylpropylpiperidinderivater og deres anvendelse som antibakterielle midler
DK1204649T3 (da)	2007-12-03	Arylmethylcarbonylaminothiazolderivater og deres anvendelse som antitumormidler
DK0906292T3 (da)	2003-10-27	Triazolylmercaptider og deres anvendelse som mikrobicider
DK1198454T3 (da)	2006-06-12	Multilinderivater og deres anvendelse som antibakterielle midler
ATE256694T1 (de)	2004-01-15	Ketolid-antibiotika
NO20005146D0 (no)	2000-10-13	Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
NO20014702L (no)	2001-09-27	Diarylderivater og deres anvendelse som medikamenter
DK1073672T3 (da)	2003-12-08	Antipicornavirale forbindelser, deres fremstilling og anvendelse
EE200100245A (et)	2002-10-15	Uued makroliidsed antibiootikumid
NO993467D0 (no)	1999-07-14	Granuler som innbefatter klavulanat og en eller flere eksipienter
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