NO20034345L - Pyridazinon aldose reduktase inhibitorer - Google Patents

Pyridazinon aldose reduktase inhibitorer

Info

Publication number: NO20034345L
Authority: NO; Norway
Prior art keywords: reductase inhibitors; aldose reductase; pyridazinone aldose; pyridazinone; inhibitors
Prior art date: 2001-03-30

Application number

NO20034345A

Other languages

English (en)

Other versions

NO20034345D0 (no

Inventor

Banavara Lakshman Mylari

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-30

Filing date

2003-09-29

Publication date

2003-09-29

2003-09-29 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-09-29 Publication of NO20034345D0 publication Critical patent/NO20034345D0/no

2003-09-29 Publication of NO20034345L publication Critical patent/NO20034345L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20034345A 2001-03-30 2003-09-29 Pyridazinon aldose reduktase inhibitorer NO20034345L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28005101P	2001-03-30	2001-03-30
PCT/IB2002/000320 WO2002079198A1 (en)	2001-03-30	2002-01-31	Pyridazinone aldose reductase inhibitors

Publications (2)

Publication Number	Publication Date
NO20034345D0 NO20034345D0 (no)	2003-09-29
NO20034345L true NO20034345L (no)	2003-09-29

Family

ID=23071435

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20034345A NO20034345L (no)	2001-03-30	2003-09-29	Pyridazinon aldose reduktase inhibitorer

Country Status (43)

Country	Link
US (2)	US6579879B2 (no)
EP (3)	EP1491540B1 (no)
JP (1)	JP2004528319A (no)
KR (1)	KR100586138B1 (no)
CN (1)	CN1215067C (no)
AP (1)	AP2002002461A0 (no)
AR (1)	AR035798A1 (no)
AT (3)	ATE348100T1 (no)
AU (1)	AU2002226634B2 (no)
BG (1)	BG108179A (no)
BR (1)	BR0208571A (no)
CA (1)	CA2442476A1 (no)
CZ (1)	CZ20032563A3 (no)
DE (3)	DE60217930T2 (no)
DK (2)	DK1373259T3 (no)
EA (1)	EA006023B1 (no)
EC (1)	ECSP034671A (no)
EE (1)	EE200300470A (no)
ES (2)	ES2274369T3 (no)
GE (1)	GEP20053675B (no)
HR (1)	HRP20030752A2 (no)
HU (1)	HUP0303644A3 (no)
IL (1)	IL156462A0 (no)
IS (3)	IS2205B (no)
MA (1)	MA27003A1 (no)
MX (1)	MXPA03008850A (no)
MY (1)	MY134304A (no)
NO (1)	NO20034345L (no)
NZ (1)	NZ528406A (no)
OA (1)	OA12453A (no)
PA (1)	PA8541801A1 (no)
PE (1)	PE20030007A1 (no)
PL (1)	PL365294A1 (no)
PT (2)	PT1373259E (no)
SI (1)	SI1373259T1 (no)
SK (1)	SK11852003A3 (no)
TN (1)	TNSN02037A1 (no)
TW (1)	TWI245762B (no)
UA (1)	UA73236C2 (no)
UY (1)	UY27237A1 (no)
WO (1)	WO2002079198A1 (no)
YU (1)	YU71403A (no)
ZA (1)	ZA200304671B (no)

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CA2838448A1 (en)	2006-06-27	2008-01-03	Takeda Pharmaceutical Company Limited	Fused cyclic compounds
ATE547394T1 (de)	2006-12-01	2012-03-15	Bristol Myers Squibb Co	N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
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CA2783699C (en)	2009-12-08	2019-01-15	Case Western Reserve University	Primary amine compounds for treating ocular disorders
US8916563B2 (en)	2010-07-16	2014-12-23	The Trustees Of Columbia University In The City Of New York	Aldose reductase inhibitors and uses thereof
CN104080451B (zh) *	2011-09-15	2016-08-24	台北医学大学	吲哚异羟肟酸和吲哚啉异羟肟酸于治疗心脏衰竭或神经损伤的用途
US9339542B2 (en) *	2013-04-16	2016-05-17	John L Couvaras	Hypertension reducing composition
MX2015014666A (es)	2013-04-17	2016-03-01	Pfizer	Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares.
CN103739547B (zh) *	2014-01-03	2015-09-02	沈阳药科大学	2-[6-甲氧基-3-(2,3-二氯苯基)甲基-4-氧代-1,4-二氢-1(4h)-喹啉基]乙酸的合成方法
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WO2017168174A1 (en)	2016-04-02	2017-10-05	N4 Pharma Uk Limited	New pharmaceutical forms of sildenafil
SI3352754T1 (sl)	2016-06-21	2021-03-31	The Trustees Of Columbia University In The City Of New York	Zaviralci aldozne reduktaze in postopki njihove uporabe
WO2018002673A1 (en)	2016-07-01	2018-01-04	N4 Pharma Uk Limited	Novel formulations of angiotensin ii receptor antagonists
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WO2018102552A1 (en)	2016-11-30	2018-06-07	Case Western Reserve University	Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof
JP2020514323A (ja)	2017-02-06	2020-05-21	ケースウエスタンリザーブユニバーシティ	短鎖デヒドロゲナーゼ活性を調節する組成物と方法
IL272246B1 (en)	2017-07-28	2025-09-01	Applied Therapeutics Inc	Derivatives of 2-(4-oxo/thioketone/azo-3-((substituted)benzo[d]thiazol-2-yl)methyl)- 3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid for use as aldose reductase inhibitors in treating galactosemia or preventing complications associated with galactosemia
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2002
- 2002-01-31 YU YU71403A patent/YU71403A/sh unknown
- 2002-01-31 WO PCT/IB2002/000320 patent/WO2002079198A1/en not_active Ceased
- 2002-01-31 HU HU0303644A patent/HUP0303644A3/hu unknown
- 2002-01-31 KR KR1020037012753A patent/KR100586138B1/ko not_active Expired - Fee Related
- 2002-01-31 DE DE60217930T patent/DE60217930T2/de not_active Expired - Fee Related
- 2002-01-31 SI SI200230071T patent/SI1373259T1/xx unknown
- 2002-01-31 AT AT04023149T patent/ATE348100T1/de not_active IP Right Cessation
- 2002-01-31 HR HR20030752A patent/HRP20030752A2/hr not_active Application Discontinuation
- 2002-01-31 UA UA2003098846A patent/UA73236C2/uk unknown
- 2002-01-31 IL IL15646202A patent/IL156462A0/xx unknown
- 2002-01-31 OA OA1200300222A patent/OA12453A/en unknown
- 2002-01-31 EA EA200300673A patent/EA006023B1/ru not_active IP Right Cessation
- 2002-01-31 MX MXPA03008850A patent/MXPA03008850A/es active IP Right Grant
- 2002-01-31 SK SK1185-2003A patent/SK11852003A3/sk unknown
- 2002-01-31 JP JP2002577823A patent/JP2004528319A/ja active Pending
- 2002-01-31 DE DE60216823T patent/DE60216823T2/de not_active Expired - Fee Related
- 2002-01-31 CA CA002442476A patent/CA2442476A1/en not_active Abandoned
- 2002-01-31 EP EP04023149A patent/EP1491540B1/en not_active Expired - Lifetime
- 2002-01-31 DK DK02716247T patent/DK1373259T3/da active
- 2002-01-31 PL PL02365294A patent/PL365294A1/xx not_active Application Discontinuation
- 2002-01-31 PT PT02716247T patent/PT1373259E/pt unknown
- 2002-01-31 DK DK04023149T patent/DK1491540T3/da active
- 2002-01-31 AU AU2002226634A patent/AU2002226634B2/en not_active Ceased
- 2002-01-31 DE DE60202452T patent/DE60202452C5/de not_active Expired - Fee Related
- 2002-01-31 PT PT04023149T patent/PT1491540E/pt unknown
- 2002-01-31 EP EP02716247A patent/EP1373259B1/en not_active Expired - Lifetime
- 2002-01-31 BR BR0208571-2A patent/BR0208571A/pt not_active IP Right Cessation
- 2002-01-31 GE GE5314A patent/GEP20053675B/en unknown
- 2002-01-31 EP EP04023150A patent/EP1491541B1/en not_active Expired - Lifetime
- 2002-01-31 AT AT02716247T patent/ATE286049T1/de active
- 2002-01-31 ES ES04023149T patent/ES2274369T3/es not_active Expired - Lifetime
- 2002-01-31 NZ NZ528406A patent/NZ528406A/en unknown
- 2002-01-31 AT AT04023150T patent/ATE352551T1/de not_active IP Right Cessation
- 2002-01-31 CN CNB028076001A patent/CN1215067C/zh not_active Expired - Fee Related
- 2002-01-31 EE EEP200300470A patent/EE200300470A/xx unknown
- 2002-01-31 ES ES02716247T patent/ES2231681T3/es not_active Expired - Lifetime
- 2002-03-21 US US10/104,664 patent/US6579879B2/en not_active Expired - Fee Related
- 2002-03-22 PA PA20028541801A patent/PA8541801A1/es unknown
- 2002-03-27 PE PE2002000246A patent/PE20030007A1/es not_active Application Discontinuation
- 2002-03-27 MY MYPI20021093A patent/MY134304A/en unknown
- 2002-03-27 UY UY27237A patent/UY27237A1/es not_active Application Discontinuation
- 2002-03-27 AR ARP020101134A patent/AR035798A1/es unknown
- 2002-03-28 AP APAP/P/2002/002461A patent/AP2002002461A0/en unknown
- 2002-03-29 TW TW091106386A patent/TWI245762B/zh not_active IP Right Cessation
- 2002-03-29 TN TNTNSN02037A patent/TNSN02037A1/fr unknown
- 2002-03-31 CZ CZ20032563A patent/CZ20032563A3/cs unknown
2003
- 2003-02-20 US US10/370,895 patent/US6849629B2/en not_active Expired - Fee Related
- 2003-06-16 IS IS6845A patent/IS2205B/is unknown
- 2003-06-17 ZA ZA200304671A patent/ZA200304671B/en unknown
- 2003-06-25 EC EC2003004671A patent/ECSP034671A/es unknown
- 2003-09-17 BG BG108179A patent/BG108179A/xx unknown
- 2003-09-17 MA MA27314A patent/MA27003A1/fr unknown
- 2003-09-29 NO NO20034345A patent/NO20034345L/no unknown
2006
- 2006-01-23 IS IS8251A patent/IS8251A/is unknown
- 2006-01-23 IS IS8250A patent/IS8250A/is unknown

Also Published As

Publication number	Publication date
WO2002079198A1 (en)	2002-10-10
IS6845A (is)	2003-06-16
EP1491541A1 (en)	2004-12-29
AR035798A1 (es)	2004-07-14
CN1215067C (zh)	2005-08-17
IL156462A0 (en)	2004-01-04
EP1491541B1 (en)	2007-01-24
UY27237A1 (es)	2002-12-31
KR100586138B1 (ko)	2006-06-07
SK11852003A3 (sk)	2004-07-07
SI1373259T1 (en)	2005-04-30
US20020143017A1 (en)	2002-10-03
ATE286049T1 (de)	2005-01-15
ATE348100T1 (de)	2007-01-15
ES2274369T3 (es)	2007-05-16
IS2205B (is)	2007-02-15
OA12453A (en)	2006-05-24
EP1491540A1 (en)	2004-12-29
MA27003A1 (fr)	2004-12-20
ZA200304671B (en)	2004-06-25
HUP0303644A2 (hu)	2004-03-01
DE60202452T2 (de)	2006-02-09
MXPA03008850A (es)	2003-12-04
DE60202452D1 (de)	2005-02-03
YU71403A (sh)	2006-05-25
NZ528406A (en)	2004-03-26
PE20030007A1 (es)	2003-01-28
DE60202452C5 (de)	2006-11-23
EP1373259B1 (en)	2004-12-29
DE60217930T2 (de)	2007-10-18
IS8251A (is)	2006-01-23
ATE352551T1 (de)	2007-02-15
JP2004528319A (ja)	2004-09-16
PA8541801A1 (es)	2002-10-28
GEP20053675B (en)	2005-11-25
EP1491540B1 (en)	2006-12-13
NO20034345D0 (no)	2003-09-29
ECSP034671A (es)	2003-08-29
US6579879B2 (en)	2003-06-17
TWI245762B (en)	2005-12-21
EA006023B1 (ru)	2005-08-25
EA200300673A1 (ru)	2003-12-25
AP2002002461A0 (en)	2002-06-30
DK1491540T3 (da)	2007-03-26
KR20030088484A (ko)	2003-11-19
MY134304A (en)	2007-12-31
PL365294A1 (en)	2004-12-27
DE60217930D1 (de)	2007-03-15
TNSN02037A1 (fr)	2005-12-23
CN1500087A (zh)	2004-05-26
EE200300470A (et)	2004-02-16
AU2002226634B2 (en)	2007-01-25
DE60216823T2 (de)	2007-10-04
IS8250A (is)	2006-01-23
PT1491540E (pt)	2007-01-31
BG108179A (en)	2004-09-30
DE60216823D1 (de)	2007-01-25
DK1373259T3 (da)	2005-03-29
US6849629B2 (en)	2005-02-01
HRP20030752A2 (en)	2005-06-30
CA2442476A1 (en)	2002-10-10
PT1373259E (pt)	2005-03-31
HUP0303644A3 (en)	2008-06-30
HK1061678A1 (en)	2004-09-30
EP1373259A1 (en)	2004-01-02
ES2231681T3 (es)	2005-05-16
US20030162784A1 (en)	2003-08-28
UA73236C2 (en)	2005-06-15
BR0208571A (pt)	2004-03-23
CZ20032563A3 (cs)	2004-05-12

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