NO20031694L - Crystalline monohydrate, process for its preparation and use thereof for the manufacture of a drug - Google Patents

Crystalline monohydrate, process for its preparation and use thereof for the manufacture of a drug

Info

Publication number: NO20031694L
Authority: NO; Norway
Prior art keywords: drug; manufacture; preparation; crystalline monohydrate; monohydrate
Prior art date: 2000-10-12

Application number

NO20031694A

Other languages

Norwegian (no)

Other versions

NO20031694D0 (en

NO328465B1 (en

Inventor

Rolf Banholzer

Manfred Graulich

Christian Kulinna

Andreas Mathes

Helmut Meissner

Peter Sieger

Peter Specht

Michael Trunk

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2003-04-11

Publication date

2003-04-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20031694(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-04-11 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2003-04-11 Publication of NO20031694D0 publication Critical patent/NO20031694D0/en

2003-04-11 Publication of NO20031694L publication Critical patent/NO20031694L/en

2010-02-22 Publication of NO328465B1 publication Critical patent/NO328465B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO20031694A 2000-10-12 2003-04-11 Crystalline monohydrate, process for the preparation thereof and use thereof for the preparation of a medicament NO328465B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050621		2000-10-12
PCT/EP2001/011225 WO2002030928A1 (en)	2000-10-12	2001-09-28	Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Publications (3)

Publication Number	Publication Date
NO20031694D0 NO20031694D0 (en)	2003-04-11
NO20031694L true NO20031694L (en)	2003-04-11
NO328465B1 NO328465B1 (en)	2010-02-22

Family

ID=7659568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20031694A NO328465B1 (en)	2000-10-12	2003-04-11	Crystalline monohydrate, process for the preparation thereof and use thereof for the preparation of a medicament

Country Status (46)

Country	Link
EP (2)	EP1326862B1 (en)
JP (1)	JP3764422B2 (en)
KR (1)	KR100823860B1 (en)
CN (2)	CN100519558C (en)
AP (1)	AP1572A (en)
AR (2)	AR034389A1 (en)
AT (1)	ATE276253T1 (en)
AU (2)	AU1499602A (en)
BG (1)	BG66161B1 (en)
BR (1)	BR0114584A (en)
CA (1)	CA2425539C (en)
CR (1)	CR6938A (en)
CZ (1)	CZ301841B6 (en)
DE (1)	DE50103666D1 (en)
DK (1)	DK1326862T3 (en)
DZ (1)	DZ3478A1 (en)
EA (1)	EA004381B1 (en)
EC (1)	ECSP034540A (en)
EE (1)	EE04567B1 (en)
EG (1)	EG24142A (en)
ES (1)	ES2228965T3 (en)
GE (1)	GEP20063905B (en)
HR (1)	HRP20030276B1 (en)
HU (1)	HU226830B1 (en)
IL (2)	IL155335A0 (en)
IS (1)	IS2339B (en)
MA (1)	MA25842A1 (en)
ME (2)	MEP40008A (en)
MX (1)	MXPA03003221A (en)
MY (1)	MY126931A (en)
NO (1)	NO328465B1 (en)
NZ (1)	NZ525733A (en)
OA (1)	OA12403A (en)
PE (1)	PE20020422A1 (en)
PL (1)	PL207870B1 (en)
PT (1)	PT1326862E (en)
RS (1)	RS50218B (en)
SA (1)	SA01220412B1 (en)
SI (1)	SI1326862T1 (en)
SK (1)	SK287009B6 (en)
TR (1)	TR200402579T4 (en)
TW (1)	TW589313B (en)
UA (1)	UA74215C2 (en)
UY (2)	UY26962A1 (en)
WO (1)	WO2002030928A1 (en)
ZA (1)	ZA200302500B (en)

Families Citing this family (74)

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US6608055B2 (en)	2001-06-22	2003-08-19	Boehringer Ingelheim Pharma Kg	Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition
IL159238A0 (en) *	2001-06-22	2004-06-01	Boehringer Ingelheim Pharma	Crystalline anticholinergic, method for its production, and use thereof in the production of a drug
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CA2544357A1 (en) *	2003-11-03	2005-05-12	Boehringer Ingelheim International Gmbh	Tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
CA2544352C (en) *	2003-11-03	2013-07-16	Boehringer Ingelheim International Gmbh	Crystalline anhydrate with anticholinergic effect
EP2067779B9 (en)	2003-11-03	2013-10-16	Boehringer Ingelheim International GmbH	Tiotropium salts, method for their production and medicinal formulas containing them
DE102004016179A1 (en) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Compounds for the treatment of proliferative processes
PL1781298T4 (en)	2004-04-22	2017-07-31	Boehringer Ingelheim International Gmbh	Pharmaceutical combinations containing benzoxazine for treating respiratory diseases
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024454A1 (en)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Novel enantiomerically pure beta agonists, process for their preparation and their use as pharmaceuticals
EP1632229B1 (en)	2004-08-11	2009-04-01	Boehringer Ingelheim Pharma GmbH & Co. KG	Medicaments for the treatment of urinary tract disorders comprising anticholinergic agents
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (en)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modification of surfaces of lactose as adjuvant for use with powder inhalants
BRPI0517282A (en) *	2004-10-21	2008-10-07	Boehringer Ingelheim Int	inhaler blister
JP2008532973A (en) *	2005-03-09	2008-08-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Novel pharmaceutical composition based on anticholinergic and PDE5-inhibitor
DE102005019201A1 (en)	2006-04-19	2006-11-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New compounds for the treatment of inflammatory diseases
CA2605688A1 (en)	2005-04-28	2006-11-02	Boehringer Ingelheim International Gmbh	Compounds for treating inflammatory diseases
EP1881980B1 (en)	2005-05-02	2012-08-22	Boehringer Ingelheim International GmbH	Novel crystalline forms of tiotropium bromide
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DE102005030733A1 (en)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient
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JP5270343B2 (en)	2005-08-15	2013-08-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Beta mimetic manufacturing method
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US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
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ATE552256T1 (en)	2005-12-19	2012-04-15	Sicor Inc	NOVEL FORM OF TIOTROPIUM BROMIDE AND PROCESS FOR PRODUCTION THEREOF
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EP1847543A1 (en)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidines for the treatment of inflammatory diseases
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2001
- 2001-09-28 CZ CZ20031025A patent/CZ301841B6/en not_active IP Right Cessation
- 2001-09-28 GE GE5214A patent/GEP20063905B/en unknown
- 2001-09-28 JP JP2002534314A patent/JP3764422B2/en not_active Expired - Lifetime
- 2001-09-28 NZ NZ525733A patent/NZ525733A/en not_active IP Right Cessation
- 2001-09-28 PT PT01983510T patent/PT1326862E/en unknown
- 2001-09-28 DE DE50103666T patent/DE50103666D1/en not_active Expired - Lifetime
- 2001-09-28 CN CNB2005100977370A patent/CN100519558C/en not_active Ceased
- 2001-09-28 CA CA002425539A patent/CA2425539C/en not_active Expired - Lifetime
- 2001-09-28 RS YU27303A patent/RS50218B/en unknown
- 2001-09-28 UA UA2003054185A patent/UA74215C2/en unknown
- 2001-09-28 MX MXPA03003221A patent/MXPA03003221A/en active IP Right Grant
- 2001-09-28 DZ DZ013478A patent/DZ3478A1/en active
- 2001-09-28 KR KR1020037005083A patent/KR100823860B1/en not_active Expired - Lifetime
- 2001-09-28 ES ES01983510T patent/ES2228965T3/en not_active Expired - Lifetime
- 2001-09-28 TR TR2004/02579T patent/TR200402579T4/en unknown
- 2001-09-28 AP APAP/P/2003/002775A patent/AP1572A/en active
- 2001-09-28 EA EA200300457A patent/EA004381B1/en not_active IP Right Cessation
- 2001-09-28 WO PCT/EP2001/011225 patent/WO2002030928A1/en not_active Ceased
- 2001-09-28 ME MEP-400/08A patent/MEP40008A/en unknown
- 2001-09-28 ME MEP-2008-400A patent/ME00243B/en unknown
- 2001-09-28 SI SI200130219T patent/SI1326862T1/en unknown
- 2001-09-28 IL IL15533501A patent/IL155335A0/en active IP Right Grant
- 2001-09-28 AU AU1499602A patent/AU1499602A/en active Pending
- 2001-09-28 HU HU0301022A patent/HU226830B1/en unknown
- 2001-09-28 DK DK01983510T patent/DK1326862T3/en active
- 2001-09-28 AU AU2002214996A patent/AU2002214996B2/en not_active Expired
- 2001-09-28 HR HR20030276A patent/HRP20030276B1/en not_active IP Right Cessation
- 2001-09-28 EE EEP200300171A patent/EE04567B1/en unknown
- 2001-09-28 EP EP01983510A patent/EP1326862B1/en not_active Expired - Lifetime
- 2001-09-28 AT AT01983510T patent/ATE276253T1/en active
- 2001-09-28 EP EP04016877A patent/EP1468998A1/en not_active Withdrawn
- 2001-09-28 BR BR0114584-3A patent/BR0114584A/en not_active Application Discontinuation
- 2001-09-28 CN CNB018171435A patent/CN1221549C/en not_active Ceased
- 2001-09-28 SK SK436-2003A patent/SK287009B6/en not_active IP Right Cessation
- 2001-09-28 OA OA1200300107A patent/OA12403A/en unknown
- 2001-09-28 PL PL366041A patent/PL207870B1/en unknown
- 2001-10-02 SA SA01220412A patent/SA01220412B1/en unknown
- 2001-10-09 TW TW090124963A patent/TW589313B/en active
- 2001-10-09 EG EG20011058A patent/EG24142A/en active
- 2001-10-10 UY UY26962A patent/UY26962A1/en not_active Application Discontinuation
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- 2001-10-10 MY MYPI20014705A patent/MY126931A/en unknown
- 2001-10-12 AR ARP010104782A patent/AR034389A1/en active IP Right Grant
2003
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- 2003-04-07 EC EC2003004540A patent/ECSP034540A/en unknown
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- 2003-04-11 NO NO20031694A patent/NO328465B1/en not_active IP Right Cessation
2008
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Also Published As

Publication number	Publication date
CN1221549C (en)	2005-10-05
EE200300171A (en)	2003-06-16
UA74215C2 (en)	2005-11-15
EE04567B1 (en)	2005-12-15
IS2339B (en)	2008-02-15
HU226830B1 (en)	2009-11-30
MXPA03003221A (en)	2004-12-03
ATE276253T1 (en)	2004-10-15
PL207870B1 (en)	2011-02-28
IS6772A (en)	2003-04-09
AP1572A (en)	2006-02-13
GEP20063905B (en)	2006-08-25
ME00243B (en)	2011-05-10
AU2002214996B2 (en)	2007-03-15
KR100823860B1 (en)	2008-04-21
ES2228965T3 (en)	2005-04-16
CN100519558C (en)	2009-07-29
NZ525733A (en)	2005-01-28
CN1733761A (en)	2006-02-15
SK4362003A3 (en)	2003-08-05
DZ3478A1 (en)	2002-04-18
BG107687A (en)	2003-09-30
KR20030042008A (en)	2003-05-27
ZA200302500B (en)	2004-04-22
CR6938A (en)	2004-10-28
HUP0301022A3 (en)	2005-12-28
MEP40008A (en)	2011-02-10
EP1326862B1 (en)	2004-09-15
ECSP034540A (en)	2003-07-25
JP3764422B2 (en)	2006-04-05
MY126931A (en)	2006-10-31
SA01220412B1 (en)	2006-11-05
UY26962A1 (en)	2002-06-20
TW589313B (en)	2004-06-01
AR034389A1 (en)	2004-02-25
EA004381B1 (en)	2004-04-29
EA200300457A1 (en)	2003-10-30
MA25842A1 (en)	2003-07-01
RS50218B (en)	2009-07-15
CA2425539A1 (en)	2003-04-11
BR0114584A (en)	2003-08-26
DE50103666D1 (en)	2004-10-21
WO2002030928A1 (en)	2002-04-18
EP1326862A1 (en)	2003-07-16
PT1326862E (en)	2004-11-30
NO20031694D0 (en)	2003-04-11
IL155335A0 (en)	2003-11-23
SI1326862T1 (en)	2005-02-28
EG24142A (en)	2008-08-06
UY34901A (en)	2015-02-27
CN1469877A (en)	2004-01-21
HRP20030276A2 (en)	2005-02-28
AR068527A2 (en)	2009-11-18
JP2004526668A (en)	2004-09-02
CZ301841B6 (en)	2010-07-07
PE20020422A1 (en)	2002-06-28
CA2425539C (en)	2007-04-03
TR200402579T4 (en)	2004-12-21
HK1086557A1 (en)	2006-09-22
DK1326862T3 (en)	2004-11-22
NO328465B1 (en)	2010-02-22
YU27303A (en)	2006-05-25
EP1468998A1 (en)	2004-10-20
OA12403A (en)	2006-04-18
PL366041A1 (en)	2005-01-24
BG66161B1 (en)	2011-09-30
AU1499602A (en)	2002-04-22
HRP20030276B1 (en)	2006-02-28
IL155335A (en)	2009-02-11
HK1060567A1 (en)	2004-08-13
SK287009B6 (en)	2009-09-07
AP2003002775A0 (en)	2003-03-31
HUP0301022A2 (en)	2003-10-28

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Date	Code	Title	Description
2021-10-11	MK1K	Patent expired