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NO20013546L - Godt renset etyl-EPA og andre EPA-derivater for psykiatriske og nevrologiske sykdommer - Google Patents

Godt renset etyl-EPA og andre EPA-derivater for psykiatriske og nevrologiske sykdommer

Info

Publication number
NO20013546L
NO20013546L NO20013546A NO20013546A NO20013546L NO 20013546 L NO20013546 L NO 20013546L NO 20013546 A NO20013546 A NO 20013546A NO 20013546 A NO20013546 A NO 20013546A NO 20013546 L NO20013546 L NO 20013546L
Authority
NO
Norway
Prior art keywords
epa
psychiatric
well
neurological disorders
derivatives
Prior art date
Application number
NO20013546A
Other languages
English (en)
Norwegian (no)
Other versions
NO20013546D0 (no
Inventor
Malcolm Peet
Krishna Vaddadi
Original Assignee
Laxdale Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laxdale Ltd filed Critical Laxdale Ltd
Publication of NO20013546D0 publication Critical patent/NO20013546D0/no
Publication of NO20013546L publication Critical patent/NO20013546L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20013546A 1999-01-27 2001-07-17 Godt renset etyl-EPA og andre EPA-derivater for psykiatriske og nevrologiske sykdommer NO20013546L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9901809.5A GB9901809D0 (en) 1999-01-27 1999-01-27 Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
PCT/GB2000/000164 WO2000044361A2 (fr) 1999-01-27 2000-01-21 Acide eicosapentanoique ethylique hautement purifie et autres derives de l'acide eicosapentanoique pour le traitement des troubles psychiatriques et neurologiques

Publications (2)

Publication Number Publication Date
NO20013546D0 NO20013546D0 (no) 2001-07-17
NO20013546L true NO20013546L (no) 2001-09-25

Family

ID=10846603

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013546A NO20013546L (no) 1999-01-27 2001-07-17 Godt renset etyl-EPA og andre EPA-derivater for psykiatriske og nevrologiske sykdommer

Country Status (34)

Country Link
US (10) US6384077B1 (fr)
EP (2) EP1148873B1 (fr)
JP (1) JP4959055B2 (fr)
KR (1) KR100760038B1 (fr)
CN (2) CN1739496A (fr)
AT (1) ATE300296T1 (fr)
AU (1) AU3065700A (fr)
BR (1) BR0007743A (fr)
CA (1) CA2360776C (fr)
CZ (1) CZ20012695A3 (fr)
DE (1) DE60021525T2 (fr)
DK (1) DK1148873T3 (fr)
EE (1) EE04629B1 (fr)
ES (1) ES2246825T3 (fr)
GB (1) GB9901809D0 (fr)
HK (1) HK1039564B (fr)
HR (1) HRP20010558A2 (fr)
HU (1) HU226713B1 (fr)
IL (2) IL144502A0 (fr)
IS (1) IS5988A (fr)
MX (1) MXPA01007662A (fr)
MY (1) MY136927A (fr)
NO (1) NO20013546L (fr)
NZ (1) NZ513172A (fr)
PL (1) PL199778B1 (fr)
PT (1) PT1148873E (fr)
RS (1) RS50133B (fr)
RU (1) RU2260423C2 (fr)
SK (1) SK10392001A3 (fr)
TR (2) TR200102170T2 (fr)
TW (1) TWI228041B (fr)
UA (1) UA76405C2 (fr)
WO (1) WO2000044361A2 (fr)
ZA (1) ZA200106105B (fr)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901809D0 (en) 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
WO2000074784A1 (fr) * 1999-06-09 2000-12-14 Eli Lilly And Company Combinaison pour le traitement du gain de poids lie a la prise de medicaments antipsychotiques comprenant un antipsychotique atypique et un antagoniste de type h2
US6737078B1 (en) * 1999-11-24 2004-05-18 The Iams Company Process for enhancing canine and feline reproductive performance
GB0016045D0 (en) 2000-06-29 2000-08-23 Laxdale Limited Therapeutic combinations of fatty acids
US20050032897A1 (en) * 2000-11-22 2005-02-10 The Iams Company Process for enhancing canine and feline reproductive performance
NL1019368C2 (nl) * 2001-11-14 2003-05-20 Nutricia Nv Preparaat voor het verbeteren van receptorwerking.
GB0210212D0 (en) * 2002-05-03 2002-06-12 Univ Southampton Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability
US8729124B2 (en) 2002-03-05 2014-05-20 Pronova Biopharma Norge As Use of EPA and DHA in secondary prevention
AU2003229993B2 (en) * 2002-05-03 2008-07-24 Pronova Biopharma Norge As Use of EPA and DHA in secondary prevention
EP2295529B2 (fr) * 2002-07-11 2022-05-18 Basf As Procédé de diminution des polluants environnementaux dans une huile ou une graisse et produit d'alimentation pour poissons
SE0202188D0 (sv) * 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
US7410663B2 (en) * 2002-08-07 2008-08-12 Kao Corporation Oil or fat composition
GB0221480D0 (en) * 2002-09-16 2002-10-23 Laxdale Ltd Treatment of anorexia nervosa (AN) and bulimia
GB0228079D0 (en) * 2002-12-02 2003-01-08 Laxdale Ltd Huntington's Disease
GB0301701D0 (en) * 2003-01-24 2003-02-26 Ensay Ltd Psoriasis and Eicosapentaenoic acid
GB0311081D0 (en) * 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
NZ527142A (en) * 2003-07-23 2006-03-31 Douglas Pharmaceuticals Ltd A stable suspension formulation
US7964641B2 (en) * 2003-08-18 2011-06-21 Btg International Limited Treatment of neurodegenerative conditions
US20050074443A1 (en) * 2003-10-03 2005-04-07 Treadwell Benjamin V. Methods of attenuating autoimmune disease and compositions useful therefor
FR2860976B1 (fr) * 2003-10-20 2006-02-10 Ravi Shrivastava Nouvelles compositions synergiques pour ameliorer la biodisponibilite et l'efficacite des acides gras polyinsatures pour le traitement des troubles du fonctionnement cerebral.
EP1683519A4 (fr) * 2003-11-14 2009-04-01 Mochida Pharm Co Ltd Agent preventif/therapeutique pour traiter les troubles de la parole
US6936598B2 (en) * 2003-11-21 2005-08-30 Hill's Pet Nutrition, Inc. Composition and method
US7754677B2 (en) * 2003-12-05 2010-07-13 Hill's Pet Nutrition, Inc. Composition and method for reducing diarrhea in a mammal
EP1711173A2 (fr) * 2003-12-31 2006-10-18 Igennus Limited Formulation contenant de l'acide eicosapentaenoique ou un ester de celui-ci et d'un triterpene ou un ester de celui-ci
ITMI20040069A1 (it) * 2004-01-21 2004-04-21 Tiberio Bruzzese Uso di composizioni di acidi grassi n-3 ad elevata concentrazione per il trattamento di disturbi del sistema nervoso centrale
EP2626368B1 (fr) 2004-07-19 2016-12-21 Biocon Limited Conjugués insuline-oligomère, formulations et utilisations de ceux-ci
US20070281892A1 (en) * 2004-09-21 2007-12-06 Martin Keith F Dopaminergic Mimetics
EP1833313A2 (fr) * 2004-10-15 2007-09-19 Corporation Limited Photonz Compositions contenant des niveaux eleves d'omega-3 et des niveaux faibles d'acides gras satures
GB0425932D0 (en) * 2004-11-25 2004-12-29 Btg Int Ltd Structured phospholipids
GB2421909A (en) * 2004-12-23 2006-07-12 Laxdale Ltd Pharmaceutical compositions comprising EPA and methods of use
US8324276B2 (en) 2005-01-24 2012-12-04 Pronova Biopharma Norge As Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction
CA2594781A1 (fr) * 2005-01-24 2006-07-27 Pronova Biocare As Utilisation d'une composition d'acides gras contenant un dha pour la production d'un produit pharmaceutique ou alimentaire destine au traitement de maladies liees a l'amylose
GB0504362D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
GB0504333D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Treatment of cytokine dysregulation
CN102050720B (zh) * 2005-05-04 2013-03-13 普罗诺瓦生物医药挪威公司 新的dha衍生物及其作为药物的用途
CN101213281B (zh) * 2005-05-04 2013-03-13 普罗诺瓦生物医药挪威公司 新的dha衍生物及其作为药物的用途
RU2441061C2 (ru) * 2005-05-04 2012-01-27 Пронова Биофарма Норге Эс. Производные докозагексаеновой кислоты и их применение в качестве лекарственных средств
CA2570763C (fr) * 2005-07-08 2011-08-23 Mochida Pharmaceutical Co., Ltd. Composition pour la prevention d'accidents cardiovasculaires
KR20130101596A (ko) * 2005-07-08 2013-09-13 마텍 바이오싸이언스스 코포레이션 치매 및 치매-전단계와 관련된 용태의 치료를 위한 다중불포화 지방산
ITMI20051560A1 (it) * 2005-08-10 2007-02-11 Tiberio Bruzzese Composizione di acidi grassi n-3 con elevata concentrazione di epa e-o dha e contenente acidi grassi n-6
ES2277557B1 (es) 2005-12-21 2008-07-01 Proyecto Empresarial Brudy, S.L. Utilizacion de acido docosahexaenoico para el tratamiento del daño celular oxidativo.
CA2632949C (fr) 2005-12-21 2012-05-22 Brudy Technology, S.L. Utilisation de dha, d'epa ou d'epa derive de dha pour traiter une pathologie associee a des dommages d'oxydation cellulaire
US20100048704A1 (en) * 2006-07-14 2010-02-25 Nattopharma Asa Pharmaceutical and nutraceutical products comprising vitamin k2
CN101535238A (zh) * 2006-11-01 2009-09-16 普罗诺瓦生物医药挪威公司 作为过氧化物酶体增生物激活受体(PPAR)的活化剂或调节剂的α-取代的ω-3脂质
US20110166228A1 (en) * 2006-11-01 2011-07-07 Anne Kristin Holmeide Composition
RU2507193C2 (ru) * 2006-11-01 2014-02-20 Пронова Биофарма Норге А/С Альфа-замещенные омега-3 липиды, которые являются активаторами или модуляторами рецептора, активируемого пролифераторами пероксисом (ppar)
JP5552314B2 (ja) * 2006-11-01 2014-07-16 プロノヴァ バイオファーマ ノルゲ アーエス 新規脂質化合物
WO2008128166A1 (fr) * 2007-04-13 2008-10-23 Concert Pharmaceuticals Inc. Dérivés deutériés de composés 4-(6-fluoro-1,2-benzisoxazol-3-yl) pipéridine
CA2639412A1 (fr) 2007-09-11 2009-03-11 Universite Laval Modulation de la prostaglandine e2 et ses utilisations
CA2702892C (fr) 2007-10-16 2017-02-28 Biocon Limited Composition pharmaceutique solide administrable par voie orale et procede associe
KR20100100818A (ko) * 2007-10-31 2010-09-15 프로노바 바이오파마 노르지 에이에스 새로운 ｄｈａ 유도체 및 약물로서 그들의 사용
US20090182049A1 (en) * 2008-01-16 2009-07-16 Joar Arild Opheim Pharmaceutical Composition and Method for Treating Hypertriglyceridemia and Hypercholesterolemia in Humans
WO2010028067A1 (fr) 2008-09-02 2010-03-11 Amarin Corporation Plc Composition pharmaceutique comprenant de l'acide eïcosapentaénoïque et de l'acide nicotinique et ses procédés d'utilisation
WO2010027266A1 (fr) * 2008-09-05 2010-03-11 Van De Langenberg, Hendrikus Theodorus Ardina Hubertus Moyens et méthodes pour corriger les troubles neurologiques
WO2010028419A1 (fr) * 2008-09-09 2010-03-18 Orygen Research Centre Prévention de troubles psychotiques et/ou traitement de symptômes psychotiques
AU2015203289B2 (en) * 2008-09-09 2017-03-16 Orygen Research Centre Prevention of psychotic disorders and/or treatment of psychotic symptoms
ES2426132T3 (es) 2009-02-10 2013-10-21 Amarin Pharmaceuticals Ireland Limited Uso del éster etílico del ácido eicosapentaenoico para tratar la hipertrigliceridemia
KR102118478B1 (ko) * 2009-03-09 2020-06-04 바스프 에이에스 지방산 오일 혼합물 및 계면활성제를 포함하는 조성물, 및 이의 방법 및 용도
GB0904300D0 (en) 2009-03-12 2009-04-22 Amarin Neuroscience Ltd Essential fatty acid compounds
DK2424356T3 (en) * 2009-04-29 2017-12-04 Amarin Pharmaceuticals Ie Ltd STABLE PHARMACEUTICAL COMPOSITION AND PROCEDURES FOR USING SAME
AU2014203034B2 (en) * 2009-04-29 2016-09-15 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
EP4008327A1 (fr) 2009-04-29 2022-06-08 Amarin Pharmaceuticals Ireland Limited Compositions pharmaceutiques comprenant de l'epa et un agent cardiovasculaire et leurs procédés d'utilisation
NZ597193A (en) 2009-06-15 2014-01-31 Amarin Pharmaceuticals Ie Ltd Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
ES2554657T3 (es) 2009-09-23 2015-12-22 Amarin Pharmaceuticals Ireland Limited Composición farmacéutica que comprende ácido graso omega-3 y derivado hidroxi de una estatina y métodos de uso de la misma
JP2011136948A (ja) * 2009-12-28 2011-07-14 Nisshin Oillio Group Ltd うつ病又はうつ状態の予防又は治療用油脂組成物
US20110178105A1 (en) * 2010-01-15 2011-07-21 E.I. Du Pont De Nemours And Company Clinical benefits of eicosapentaenoic acid in humans
CA2792090C (fr) * 2010-03-04 2019-05-14 Amarin Pharma, Inc. Compositions et methodes pour le traitement et/ou la prevention de maladies cardio-vasculaires
GB201020133D0 (en) 2010-11-26 2011-01-12 Royal Holloway & Bedford New College Therapeutic use of compounds
WO2012074930A2 (fr) * 2010-11-29 2012-06-07 Amarin Pharma, Inc. Composition à faible éructation et méthodes de traitement et/ou de prévention de maladie cardiovasculaire chez un sujet présentant une allergie/hypersensibilité aux poissons
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
WO2012109539A1 (fr) * 2011-02-11 2012-08-16 E. I. Du Pont De Nemours And Company Concentré d'acide eicosapentaénoïque
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
US8715648B2 (en) 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US20120252888A1 (en) * 2011-03-29 2012-10-04 Palupa Medical Ltd. Compositions and Methods for Treating Neurologic Disorders
WO2013070735A1 (fr) 2011-11-07 2013-05-16 Amarin Pharmaceuticals Ireland Limited Méthodes de traitement de l'hypertriglycéridémie
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
AU2013207368A1 (en) 2012-01-06 2014-07-24 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-CRP) in a subject
AU2013235266B2 (en) 2012-03-20 2017-10-19 Particle Dynamics International, Llc Gelling agent-based dosage form
NZ737380A (en) 2012-06-29 2019-05-31 Amarin Pharmaceuticals Ie Ltd Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
RU2020125675A (ru) * 2012-06-29 2020-09-16 Амарин Фармасьютикалз Айрлэнд Лимитед Способы лечения педиатрического метаболического синдрома
WO2014052394A1 (fr) 2012-09-26 2014-04-03 Feuerstein Seth D Procédés et compositions de combinaison comprenant une thérapie du sommeil pour traiter l'humeur
US20150265566A1 (en) 2012-11-06 2015-09-24 Amarin Pharmaceuticals Ireland Limited Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
JP2016501249A (ja) * 2012-12-06 2016-01-18 マティナス バイオファーマ インコーポレイテッド ドコサペンタエン酸を含む組成物の投与
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US20150374660A1 (en) * 2013-02-26 2015-12-31 Jiva Pharma, Inc. Ascorbate Esters of Omega-3 Fatty Acids and Their Formulations and Uses
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
CA2932766C (fr) 2013-12-05 2018-05-01 Enzymotec Ltd. Preparation de glycerophospholipides de serine et methode de traitement de crises d'epilepsie
EP2883860B1 (fr) * 2013-12-11 2016-08-24 Novasep Process Procédé chromatographique de production d'acides gras polyinsaturés
EP3092218B1 (fr) 2014-01-07 2022-03-09 Novasep Process Solutions Procédé de purification d'acides aminés aromatiques
US9540307B2 (en) 2014-05-08 2017-01-10 Jiva Pharma, Inc. Statins of omega-3 polyunsaturated acids for treating hypercholesterolemia
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
RU2582962C1 (ru) * 2014-12-23 2016-04-27 Ольга Алексеевна Громова Средство для профилактики и лечения нейродегенеративной патологии и сосудистой деменции (варианты)
US10183044B2 (en) 2015-05-15 2019-01-22 P Tech, Llc Systems and methods for thrombosis prevention
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
WO2018213663A1 (fr) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions et méthodes pour dimunuer les triglycérides chez un sujet ayant une fonction rénale réduite
US11065288B2 (en) * 2017-09-29 2021-07-20 Kinjirushi Co., Ltd. Neuron activator
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
US20190385718A1 (en) 2018-06-14 2019-12-19 Astrazeneca Uk Limited Methods for lowering triglyceride levels with a concentrated fish oil-based pharmaceutical composition
CN108721269A (zh) * 2018-07-10 2018-11-02 广东海洋大学 一种epa与dha混合剂在防治焦虑和快感缺乏方面的应用
CN111991386A (zh) 2018-09-24 2020-11-27 阿马里纳药物爱尔兰有限公司 降低受试者的心血管事件的风险的方法
CN116350616A (zh) 2019-11-12 2023-06-30 阿马里纳药物爱尔兰有限公司 降低心房纤颤和/或心房扑动受试者心血管事件风险的方法
US20230097753A1 (en) * 2020-01-29 2023-03-30 Universitat De Les Illes Balears Alpha-hydroxylated fatty-acid metabolites, medical uses and use as biomarkers
EP4125856A1 (fr) * 2020-03-23 2023-02-08 S.L.A. Pharma AG Acide eicosapentaénoïque hautement purifié, en tant qu'acide gras libre pour le traitement de coronavirus et spécifiquement du nouveau coronavirus -19 (covid-19)
KR20240012390A (ko) 2021-04-21 2024-01-29 애머린 파마슈티칼스 아일랜드 리미티드 심부전의 위험을 감소시키는 방법
CN119504664B (zh) * 2025-01-17 2025-06-24 广东医科大学附属医院 二十碳五烯酸衍生物及其制备方法和应用、防治神经系统疾病药物

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1021147A (en) * 1972-10-30 1977-11-22 Stephen S. Trond Method for preparing oxysulfide phosphors with large particle size
US4377526A (en) * 1981-05-15 1983-03-22 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid and its esters
CA1239587A (fr) 1983-10-24 1988-07-26 David Rubin Compose d'acides gras pour abaisser les taux de cholesterol et de triglycerides sanguins
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4727340A (en) * 1986-04-30 1988-02-23 Tektronix, Inc. Comb generators
US4920098A (en) * 1986-09-17 1990-04-24 Baxter International Inc. Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases
US5252333A (en) 1987-04-27 1993-10-12 Scotia Holdings Plc Lithium salt-containing pharmaceutical compositions
DE3719097C1 (de) * 1987-06-06 1988-06-09 Fratzer Uwe Arzneimittel,enthaltend Eicosapentaensaeure und Docosahexaensaeure als ungesaettigte Fettsaeuren sowie Vitamin E
US5198468A (en) * 1987-06-24 1993-03-30 Efamol Holdings Plc Essential fatty acid composition
US4843095A (en) 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
CA1338683C (fr) * 1988-09-13 1996-10-29 Efamol Holdings Plc Compositions a base d'acides gras et applications therapeutiques
GB2223943A (en) 1988-10-21 1990-04-25 Tillotts Pharma Ag Oral disage forms of omega-3 polyunsaturated acids
US4935243A (en) * 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
JP2839276B2 (ja) * 1989-01-23 1998-12-16 日本分光工業株式会社 超臨界流体抽出・分離方法及び装置
GB8906369D0 (en) * 1989-03-20 1989-05-04 Tisdale Michael J Eicosapentaenoic acid
US5457130A (en) * 1989-03-20 1995-10-10 Cancer Research Campaign Technology Limited Eicosapentaenoic acid used to treat cachexia
JPH0358926A (ja) * 1989-07-27 1991-03-14 Taiyo Fishery Co Ltd 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤、痴呆治療剤、または脳機能改善効果を有する機能性食品
CA2043615C (fr) * 1990-06-04 2001-08-14 Kazuhiko Hata Methode de preparation de l'acide icosapentenoique ou d'un ester de ce dernier
GB9012651D0 (en) * 1990-06-06 1990-07-25 Efamol Holdings Essential fatty acid treatment
JP3103588B2 (ja) * 1990-11-16 2000-10-30 持田製薬株式会社 リポプロテイン（ａ）低下剤
SE9101642D0 (sv) 1991-05-30 1991-05-30 Kabi Pharmacia Ab Phospholipids
US5215630A (en) * 1991-06-04 1993-06-01 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid or the ester derivative thereof by fractional distillation
DE4133694C2 (de) * 1991-10-11 1993-10-07 Fresenius Ag Verwendung einer Emulsion mit mehrfach ungesättigten Fettsären zur i.v.-Verabreichung zur Behandlung von Hauterkrankungen
JP3400466B2 (ja) * 1991-10-28 2003-04-28 日本水産株式会社 高純度エイコサペンタエン酸またはそのエステルの製造方法
RU2055590C1 (ru) * 1992-03-10 1996-03-10 Научно-производственное предприятие "Тринита" Способ лечения атерогенных дислипопротеидемий
JPH0649479A (ja) * 1992-07-28 1994-02-22 Maruha Corp ω−３不飽和脂肪酸系化合物の安定化法
US5516801A (en) * 1992-08-21 1996-05-14 Scotia Holdings Plc Fatty acid treatment for ectopic calcium deposition
GB9217780D0 (en) * 1992-08-21 1992-10-07 Efamol Holdings Fatty acid treatment
US5888541A (en) * 1992-08-21 1999-03-30 Scotia Holdings Plc Fatty acid treatment
GB9300125D0 (en) * 1993-01-06 1993-03-03 Scotia Holdings Plc Compositions containing esters of unsaturated fatty acids
WO1994028891A1 (fr) 1993-06-04 1994-12-22 Martek Biosciences Corporation Procede permettant le traitement d'une coronaropathie au moyen d'acide docosahexaenoique
GB9403857D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives
US5760081A (en) * 1994-05-10 1998-06-02 The General Hospital Corporation Omega 3 fatty acids in the prevention of ventricular fibrillation
AU711482B2 (en) * 1994-06-28 1999-10-14 Scotia Holdings Plc Compositions for treatment of diabetic complications
IT1274734B (it) * 1994-08-25 1997-07-24 Prospa Bv Composizioni farmaceutiche contenenti acidi grassi poliinsaturi, loro esteri o sali, unitamente a vitamine o provitamine antiossidanti
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
GB9509764D0 (en) * 1995-05-15 1995-07-05 Tillotts Pharma Ag Treatment of inflammatory bowel disease using oral dosage forms of omega-3 polyunsaturated acids
GB9519661D0 (en) * 1995-09-27 1995-11-29 Scotia Holdings Plc Fatty acid treatment
JP3552810B2 (ja) 1995-09-27 2004-08-11 松下電器産業株式会社 部品供給部の部品一括交換方法と装置
WO1997039759A2 (fr) * 1996-04-24 1997-10-30 Brigham And Women's Hospital Acides gras omega 3 et phosphatidylcholine omega 3 utilises dans le traitement de troubles bipolaires
US5861399A (en) * 1996-07-17 1999-01-19 Heart Care Partners Methods and compositions for the rapid and enduring relief of inadequate myocardial function
US20020055539A1 (en) * 1996-10-02 2002-05-09 Bockow Barry I. Compositions and methods for treating cardiovascular conditions
DK0956013T3 (da) * 1996-10-11 2003-08-04 Scarista Ltd Farmaceutisk præparat indeholdende eicosapentaensyre og/eller stearidonsyre
DE69825173T2 (de) * 1997-10-30 2005-08-25 Morishita Jintan Co. Ltd. Doppelschichtige kapsel von ungesättigten fettsäuren oder deren derivate und verfahren zu deren herstellung
CA2313024C (fr) * 1997-12-10 2008-06-03 Severson, Mary L. Compositions pharmaceutiques contenant une huile d'acide gras omega-3
GB9901809D0 (en) * 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
US20030104048A1 (en) * 1999-02-26 2003-06-05 Lipocine, Inc. Pharmaceutical dosage forms for highly hydrophilic materials
US6193999B1 (en) * 1999-03-01 2001-02-27 Banner Pharmacaps, Inc. Gum acacia substituted soft gelatin capsules
ATE394941T1 (de) * 1999-07-28 2008-05-15 Swiss Caps Rechte & Lizenzen Präparat zur verwendung als medikament und/oder nahrungsmittelergänzung
EP1211955A1 (fr) 1999-08-30 2002-06-12 Ocean Nutrition Canada Ltd. Supplement nutritionnel destine a abaisser le taux de cholesterol et de triglycerides seriques
EP1157692B1 (fr) 2000-05-22 2005-10-05 Pro Aparts - Investimentos E Consultoria Lda Composition pharmaceutique d'acides gras, contenant au moins 80% en poids de EPA et DHA
GB0016045D0 (en) 2000-06-29 2000-08-23 Laxdale Limited Therapeutic combinations of fatty acids
ITMI20010129A1 (it) 2001-01-25 2002-07-25 Pharmacia & Upjohn Spa Acidi grassi essenziali nella terapia di insufficienza cardiaca e scompenso cardiaco
GB0111282D0 (en) 2001-05-09 2001-06-27 Laxdale Ltd Potentiation of therapeutic effects of fatty acids
CZ299784B6 (cs) 2001-05-30 2008-11-26 Laxdale Limited Lécivo obsahující EPA a ubichinon pro lécení non-Hodgkinova lymfomu, psychiatrických a neurologických chorob
ITMI20012384A1 (it) * 2001-11-12 2003-05-12 Quatex Nv Uso di acidi grassi poliinsaturi per la prevenzione primaria di eventi cardiovascolari maggiori
ITMI20020269A1 (it) 2002-02-12 2003-08-12 Victorix Assets Ltd Uso di steri etilici di acidi poliinsaturi omega-3 in pazienti con insufficienza cardiaca
US20030166614A1 (en) * 2002-03-01 2003-09-04 Harrison Stanley F. Method for reducing cholesterol and triglycerides
US20070087137A9 (en) * 2003-06-26 2007-04-19 Elwakil Hamdy A Decorative laminated safety glass
KR100956404B1 (ko) * 2002-08-20 2010-05-06 교와 가부시키가이샤 연질캡슐제
KR100539027B1 (ko) 2002-10-18 2005-12-26 현대모비스 주식회사 차량의 조향각 검출 장치
EP1571195A4 (fr) * 2002-11-22 2009-08-26 Nippon Suisan Kaisha Ltd Composition d'application externe contenant un acide gras fortement insature ou son sel ou ester
JP2006519244A (ja) 2003-03-05 2006-08-24 ゾルファイ　ファーマスーティカルズ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 糖尿病患者の治療におけるω−３−脂肪酸の使用
EP1711173A2 (fr) * 2003-12-31 2006-10-18 Igennus Limited Formulation contenant de l'acide eicosapentaenoique ou un ester de celui-ci et d'un triterpene ou un ester de celui-ci
US20070191467A1 (en) * 2004-12-06 2007-08-16 Reliant Pharmaceutical, Inc. Statin and omega-3 fatty acids for lipid therapy
JP2008522970A (ja) * 2004-12-06 2008-07-03 レリアント ファーマスーティカルズ インコーポレイテッド 脂質療法用のオメガ−３脂肪酸類及び異常脂質血症薬剤
US20060135610A1 (en) * 2004-12-22 2006-06-22 Bortz Jonathan D Cardiovascular compositions
GB2421909A (en) * 2004-12-23 2006-07-12 Laxdale Ltd Pharmaceutical compositions comprising EPA and methods of use
US7628027B2 (en) 2005-07-19 2009-12-08 Hussmann Corporation Refrigeration system with mechanical subcooling
ITMI20051560A1 (it) 2005-08-10 2007-02-11 Tiberio Bruzzese Composizione di acidi grassi n-3 con elevata concentrazione di epa e-o dha e contenente acidi grassi n-6
US20070104779A1 (en) * 2005-11-07 2007-05-10 Rongen Roelof M Treatment with omega-3 fatty acids and products thereof
EP1968567B1 (fr) * 2005-12-20 2014-06-18 Cenestra, Llc Preparations a base d'acide gras omega 3
CA2571462C (fr) * 2006-02-07 2013-08-13 Mochida Pharmaceutical Co., Ltd. Composition pour la prevention de la recurrence d'un accident vasculaire cerebral
WO2008012329A2 (fr) * 2006-07-28 2008-01-31 V. Mane Fils Gélules sans soudure contenant de grandes quantités d'acides gras polyinsaturés et un composant aromatisant
ES2426132T3 (es) * 2009-02-10 2013-10-21 Amarin Pharmaceuticals Ireland Limited Uso del éster etílico del ácido eicosapentaenoico para tratar la hipertrigliceridemia
NZ597193A (en) * 2009-06-15 2014-01-31 Amarin Pharmaceuticals Ie Ltd Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
WO2013192109A1 (fr) * 2012-06-17 2013-12-27 Matinas Biopharma, Inc. Compositions d'acide pentanoïque oméga-3 et leurs procédés d'utilisation

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US8188146B2 (en) 2012-05-29
EE200100387A (et) 2003-02-17
US6689812B2 (en) 2004-02-10
HK1039564B (en) 2005-12-09
HU226713B1 (en) 2009-07-28
JP2002535355A (ja) 2002-10-22
NO20013546D0 (no) 2001-07-17
DK1148873T3 (da) 2005-11-28
RU2260423C2 (ru) 2005-09-20
KR20010108131A (ko) 2001-12-07
TR200102170T2 (tr) 2001-12-21
PL199778B1 (pl) 2008-10-31
EP1148873A2 (fr) 2001-10-31
YU54201A (sh) 2004-07-15
US20020077361A1 (en) 2002-06-20
US6384077B1 (en) 2002-05-07
BR0007743A (pt) 2001-11-27
KR100760038B1 (ko) 2007-10-04
MXPA01007662A (es) 2003-06-24
ATE300296T1 (de) 2005-08-15
US7119118B2 (en) 2006-10-10
MY136927A (en) 2008-11-28
UA76405C2 (en) 2006-08-15
US20040162348A1 (en) 2004-08-19
EP1417963A1 (fr) 2004-05-12
IL144502A0 (en) 2002-05-23
CN100423718C (zh) 2008-10-08
US20080200547A1 (en) 2008-08-21
US20020193439A1 (en) 2002-12-19
JP4959055B2 (ja) 2012-06-20
ZA200106105B (en) 2003-04-30
IL144502A (en) 2006-12-31
US20110065793A1 (en) 2011-03-17
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TR200504156T2 (tr) 2006-07-21

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