NO20003315L - Indol-derivater anvendelige bl a for behandling av osteoporose - Google Patents
Indol-derivater anvendelige bl a for behandling av osteoporoseInfo
- Publication number
- NO20003315L NO20003315L NO20003315A NO20003315A NO20003315L NO 20003315 L NO20003315 L NO 20003315L NO 20003315 A NO20003315 A NO 20003315A NO 20003315 A NO20003315 A NO 20003315A NO 20003315 L NO20003315 L NO 20003315L
- Authority
- NO
- Norway
- Prior art keywords
- osteoporosis
- treatment
- inter alia
- indole derivatives
- derivatives useful
- Prior art date
Links
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97403154 | 1997-12-24 | ||
| PCT/EP1998/008561 WO1999033822A1 (en) | 1997-12-24 | 1998-12-17 | Indole derivatives useful a.o. for the treatment of osteoporosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20003315D0 NO20003315D0 (no) | 2000-06-23 |
| NO20003315L true NO20003315L (no) | 2000-06-23 |
| NO320272B1 NO320272B1 (no) | 2005-11-14 |
Family
ID=8229937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003315A NO320272B1 (no) | 1997-12-24 | 2000-06-23 | Indolderivater, deres fremstilling og formulering i farmasoytiske preparater anvendbare for behandling av osteoporose og beslektede sykdommer |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1042316B1 (no) |
| JP (1) | JP4627881B2 (no) |
| KR (1) | KR20010033528A (no) |
| CN (1) | CN1208333C (no) |
| AR (1) | AR018032A1 (no) |
| AT (1) | ATE288909T1 (no) |
| AU (1) | AU749319B2 (no) |
| BR (1) | BR9814403A (no) |
| CA (1) | CA2315723A1 (no) |
| CO (1) | CO4970811A1 (no) |
| DE (1) | DE69828998T2 (no) |
| ES (1) | ES2236971T3 (no) |
| HU (1) | HUP0100785A3 (no) |
| IL (1) | IL136720A0 (no) |
| NO (1) | NO320272B1 (no) |
| NZ (1) | NZ505060A (no) |
| PL (1) | PL191633B1 (no) |
| SA (1) | SA99200109B1 (no) |
| SI (1) | SI1042316T1 (no) |
| TR (1) | TR200001992T2 (no) |
| WO (1) | WO1999033822A1 (no) |
| ZA (1) | ZA9811758B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9914371D0 (en) * | 1999-06-18 | 1999-08-18 | Smithkline Beecham Plc | Novel compounds |
| GB9914825D0 (en) | 1999-06-24 | 1999-08-25 | Smithkline Beecham Spa | Novel compounds |
| ATE430730T1 (de) * | 2000-03-31 | 2009-05-15 | Ortho Mcneil Pharm Inc | Phenyl-substituierte indole als h3 histaminrezeptorantagonisten |
| US6908929B2 (en) | 2000-03-31 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Phenyl-substituted imidazopyridines |
| US6872834B2 (en) | 2000-03-31 | 2005-03-29 | Ortho-Mcneil Pharmaceutical, Inc. | Phenyl-substituted indoles and indazoles |
| ITMI20040875A1 (it) * | 2004-04-30 | 2004-07-30 | Ist Naz Stud Cura Dei Tumori | Derivati indolici utili per il trattamento della resistenza agli agenti antitumorali |
| US20090142832A1 (en) | 2007-11-29 | 2009-06-04 | James Dalton | Indoles, Derivatives, and Analogs Thereof and Uses Therefor |
| AR072297A1 (es) | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
| SI3209655T1 (sl) * | 2014-10-24 | 2020-11-30 | Landos Biopharma, Inc. | Terapevtiki na osnovi C-podobne lantionin sintetaze 2 |
| EA202091325A1 (ru) | 2017-11-30 | 2020-08-28 | Лэндос Байофарма, Инк. | Способы лечения с помощью лигандов лантионин c-подобного белка 2 и подготовленных с их помощью клеток |
| WO2021127472A1 (en) | 2019-12-20 | 2021-06-24 | Landos Biopharma, Inc. | Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3542827B2 (ja) * | 1994-07-15 | 2004-07-14 | 帝国臓器製薬株式会社 | 新規な5−置換イソキサゾール−3−カルボン酸アミド誘導体 |
| SK93297A3 (en) * | 1995-01-10 | 1998-02-04 | Smithkline Beecham Spa | Indole derivatives, method for their producing, pharmaceutical comosition containing the same, and their use |
| US6172084B1 (en) * | 1997-06-19 | 2001-01-09 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| US6207679B1 (en) * | 1997-06-19 | 2001-03-27 | Sepracor, Inc. | Antimicrobial agents uses and compositions related thereto |
-
1998
- 1998-12-17 AT AT98966951T patent/ATE288909T1/de not_active IP Right Cessation
- 1998-12-17 HU HU0100785A patent/HUP0100785A3/hu unknown
- 1998-12-17 KR KR1020007007030A patent/KR20010033528A/ko not_active Ceased
- 1998-12-17 CA CA002315723A patent/CA2315723A1/en not_active Abandoned
- 1998-12-17 WO PCT/EP1998/008561 patent/WO1999033822A1/en not_active Ceased
- 1998-12-17 IL IL13672098A patent/IL136720A0/xx unknown
- 1998-12-17 TR TR2000/01992T patent/TR200001992T2/xx unknown
- 1998-12-17 SI SI9830765T patent/SI1042316T1/xx unknown
- 1998-12-17 NZ NZ505060A patent/NZ505060A/xx unknown
- 1998-12-17 AU AU27154/99A patent/AU749319B2/en not_active Ceased
- 1998-12-17 BR BR9814403-0A patent/BR9814403A/pt not_active Application Discontinuation
- 1998-12-17 PL PL341318A patent/PL191633B1/pl not_active IP Right Cessation
- 1998-12-17 EP EP98966951A patent/EP1042316B1/en not_active Expired - Lifetime
- 1998-12-17 JP JP2000526504A patent/JP4627881B2/ja not_active Expired - Fee Related
- 1998-12-17 DE DE69828998T patent/DE69828998T2/de not_active Expired - Fee Related
- 1998-12-17 CN CNB988137917A patent/CN1208333C/zh not_active Expired - Fee Related
- 1998-12-17 ES ES98966951T patent/ES2236971T3/es not_active Expired - Lifetime
- 1998-12-22 ZA ZA9811758A patent/ZA9811758B/xx unknown
- 1998-12-22 AR ARP980106609A patent/AR018032A1/es unknown
- 1998-12-23 CO CO98076414A patent/CO4970811A1/es unknown
-
1999
- 1999-05-11 SA SA99200109A patent/SA99200109B1/ar unknown
-
2000
- 2000-06-23 NO NO20003315A patent/NO320272B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA9811758B (en) | 2000-06-22 |
| WO1999033822A1 (en) | 1999-07-08 |
| NO20003315D0 (no) | 2000-06-23 |
| HUP0100785A3 (en) | 2001-09-28 |
| JP2003532616A (ja) | 2003-11-05 |
| JP4627881B2 (ja) | 2011-02-09 |
| NO320272B1 (no) | 2005-11-14 |
| SA99200109B1 (ar) | 2006-09-13 |
| BR9814403A (pt) | 2000-10-10 |
| AU749319B2 (en) | 2002-06-20 |
| IL136720A0 (en) | 2001-06-14 |
| KR20010033528A (ko) | 2001-04-25 |
| CN1208333C (zh) | 2005-06-29 |
| DE69828998T2 (de) | 2006-05-04 |
| HUP0100785A2 (hu) | 2001-08-28 |
| DE69828998D1 (de) | 2005-03-17 |
| CA2315723A1 (en) | 1999-07-08 |
| EP1042316B1 (en) | 2005-02-09 |
| PL191633B1 (pl) | 2006-06-30 |
| TR200001992T2 (tr) | 2001-01-22 |
| CO4970811A1 (es) | 2000-11-07 |
| ES2236971T3 (es) | 2005-07-16 |
| HK1032953A1 (en) | 2001-08-10 |
| SI1042316T1 (no) | 2005-08-31 |
| CN1299357A (zh) | 2001-06-13 |
| PL341318A1 (en) | 2001-04-09 |
| NZ505060A (en) | 2002-09-27 |
| AU2715499A (en) | 1999-07-19 |
| EP1042316A1 (en) | 2000-10-11 |
| AR018032A1 (es) | 2001-10-31 |
| ATE288909T1 (de) | 2005-02-15 |
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