|
US5019556A
(en)
*
|
1987-04-14 |
1991-05-28 |
President And Fellows Of Harvard College |
Inhibitors of angiogenin
|
|
CA1340323C
(en)
*
|
1988-09-20 |
1999-01-19 |
Arnold E. Hampel |
Rna catalyst for cleaving specific rna sequences
|
|
US5866701A
(en)
*
|
1988-09-20 |
1999-02-02 |
The Board Of Regents For Northern Illinois University Of Dekalb |
HIV targeted hairpin ribozymes
|
|
US5624824A
(en)
*
|
1989-03-24 |
1997-04-29 |
Yale University |
Targeted cleavage of RNA using eukaryotic ribonuclease P and external guide sequence
|
|
US5168053A
(en)
*
|
1989-03-24 |
1992-12-01 |
Yale University |
Cleavage of targeted RNA by RNAase P
|
|
DE4091533T
(no)
*
|
1989-08-31 |
1992-01-30 |
|
|
|
US5225337A
(en)
*
|
1989-09-25 |
1993-07-06 |
Innovir Laboratories, Inc. |
Ribozyme compositions and methods for use
|
|
US5225347A
(en)
*
|
1989-09-25 |
1993-07-06 |
Innovir Laboratories, Inc. |
Therapeutic ribozyme compositions and expression vectors
|
|
DE3933384A1
(de)
*
|
1989-10-06 |
1991-04-18 |
Hoechst Ag |
Multifunktionelle rna mit selbstprozessierungsaktivitaet, ihre herstellung und ihre verwendung
|
|
DE3935473A1
(de)
*
|
1989-10-25 |
1991-05-02 |
Hoechst Ag |
Rna mit endonuclease- und antisense-aktivitaet, ihre herstellung und ihre verwendung
|
|
WO1991010671A1
(en)
*
|
1990-01-11 |
1991-07-25 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for detecting and modulating rna activity and gene expression
|
|
US5519164A
(en)
*
|
1990-02-01 |
1996-05-21 |
Hoechst Aktiengesellschaft |
Expression of a multigene RNA having self-splicing activity
|
|
DE4002885A1
(de)
*
|
1990-02-01 |
1991-08-08 |
Hoechst Ag |
Expression einer multigen rna mit self-splicing aktivitaet
|
|
US5180818A
(en)
*
|
1990-03-21 |
1993-01-19 |
The University Of Colorado Foundation, Inc. |
Site specific cleavage of single-stranded dna
|
|
AU7152191A
(en)
*
|
1990-06-07 |
1991-12-31 |
City Of Hope |
Ribozyme mediated reversal of transformation by cleavage of the hras oncogene rna
|
|
WO1991018913A1
(en)
*
|
1990-06-07 |
1991-12-12 |
City Of Hope |
Ribozyme mediated reversal of transformation by cleavage of the hras oncogene rna
|
|
US6008343A
(en)
*
|
1990-06-19 |
1999-12-28 |
Gene Shears Pty. Ltd. |
Nucleotide based endonucleases
|
|
EP0535067B1
(en)
*
|
1990-06-19 |
1997-03-26 |
Gene Shears Pty. Ltd. |
Endonucleases
|
|
US5246921A
(en)
*
|
1990-06-26 |
1993-09-21 |
The Wistar Institute Of Anatomy And Biology |
Method for treating leukemias
|
|
CA2086105A1
(en)
*
|
1990-06-26 |
1991-12-27 |
Premkumar Reddy |
Method for treating leukemias
|
|
AU8294291A
(en)
*
|
1990-07-26 |
1992-02-18 |
Foundation For Research And Technology - Hellas (Fo.R.T.H.) Institute Of Molecular Biology & Biotechnology |
Portable ribozyme cassettes, dna sequences containing them, ribozymes encoded by these dna sequences, and compositions containing these ribozymes
|
|
DE69123979T2
(de)
*
|
1990-10-12 |
1997-04-30 |
Max Planck Gesellschaft |
Abgeänderte ribozyme
|
|
NZ241310A
(en)
*
|
1991-01-17 |
1995-03-28 |
Gen Hospital Corp |
Trans-splicing ribozymes
|
|
NZ314630A
(en)
*
|
1991-01-17 |
2000-11-24 |
Harvard College |
Use of trans-splicing ribozymes for genetic modification and cell ablation in a host cell
|
|
FR2675803B1
(fr)
*
|
1991-04-25 |
1996-09-06 |
Genset Sa |
Oligonucleotides fermes, antisens et sens et leurs applications.
|
|
FI913197A0
(fi)
|
1991-07-01 |
1991-07-01 |
Xyrofin Oy |
Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
|
|
EP0623171A4
(en)
*
|
1992-01-13 |
1997-02-12 |
Univ Duke |
ENZYMATIC RNA MOLECULES.
|
|
ATE209683T1
(de)
*
|
1992-04-17 |
2001-12-15 |
Kirin Brewery |
Planze resistent gegen mindestens zwei viren und dessen preparation
|
|
EP0652705B1
(en)
*
|
1992-06-29 |
2005-12-14 |
Gene Shears Pty Limited |
Nucleic acids and methods of use thereof for controlling viral pathogens
|
|
US5631115A
(en)
*
|
1992-07-02 |
1997-05-20 |
Sankyo Company, Limited |
Looped, hairpin ribozyme
|
|
US5409823A
(en)
*
|
1992-09-24 |
1995-04-25 |
Ciba-Geigy Corporation |
Methods for the production of hybrid seed
|
|
US5985620A
(en)
*
|
1992-11-03 |
1999-11-16 |
Gene Shears Pty. Limited |
TNF-α Ribozymes
|
|
US5864028A
(en)
*
|
1992-11-03 |
1999-01-26 |
Gene Shears Pty. Limited |
Degradation resistant mRNA derivatives linked to TNF-α ribozymes
|
|
EP0674707A4
(en)
*
|
1992-12-04 |
1998-01-14 |
Apollon Inc |
COMPOUNDS AND METHODS FOR THE TREATMENT OF LEUCOMA.
|
|
AU679525B2
(en)
*
|
1992-12-04 |
1997-07-03 |
Innovir Laboratories, Inc. |
Regulatable nucleic acid therapeutic and methods of use thereof
|
|
WO1994013833A1
(en)
*
|
1992-12-04 |
1994-06-23 |
Innovir Laboratories, Inc. |
Ribozyme amplified diagnostics
|
|
FR2701960B1
(fr)
*
|
1993-02-26 |
2002-09-13 |
Gene Shears Pty Ltd |
Polyribozyme apte à conférer, aux plantes, une résistance aux virus et plantes résistantes produisant ce polyribozyme.
|
|
US5817635A
(en)
*
|
1993-08-09 |
1998-10-06 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Modified ribozymes
|
|
AU5334294A
(en)
*
|
1993-10-15 |
1995-05-04 |
Dkfz Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts |
Asymmetric hammerhead ribozymes and nucleotide sequences for their construction
|
|
US5869248A
(en)
*
|
1994-03-07 |
1999-02-09 |
Yale University |
Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
|
|
US5998193A
(en)
*
|
1994-06-24 |
1999-12-07 |
Gene Shears Pty., Ltd. |
Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof
|
|
US6350934B1
(en)
|
1994-09-02 |
2002-02-26 |
Ribozyme Pharmaceuticals, Inc. |
Nucleic acid encoding delta-9 desaturase
|
|
US5683873A
(en)
*
|
1995-01-13 |
1997-11-04 |
Innovir Laboratories, Inc. |
EGS-mediated inactivation of target RNA
|
|
US6057153A
(en)
*
|
1995-01-13 |
2000-05-02 |
Yale University |
Stabilized external guide sequences
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
NZ308970A
(en)
*
|
1995-06-07 |
1999-10-28 |
Commw Scient Ind Res Org |
Optimized minizymes and miniribozymes and uses thereof
|
|
US6010904A
(en)
*
|
1995-06-07 |
2000-01-04 |
The General Hospital Corporation |
Cell ablation using trans-splicing ribozymes
|
|
US6004806A
(en)
*
|
1995-06-07 |
1999-12-21 |
Commonwealth Scientific And Industrial Research Organization |
Optimized minizymes and miniribozymes and uses thereof
|
|
WO1997010328A2
(en)
*
|
1995-07-13 |
1997-03-20 |
Ribozyme Pharmaceuticals, Inc. |
Compositions and method for modulation of gene expression in plants
|
|
US5824519A
(en)
*
|
1995-11-08 |
1998-10-20 |
Medical University Of South Carolina |
Tissue-specific and target RNA-specific ribozymes
|
|
US5877162A
(en)
*
|
1996-03-14 |
1999-03-02 |
Innovir Laboratories, Inc. |
Short external guide sequences
|
|
US6620805B1
(en)
|
1996-03-14 |
2003-09-16 |
Yale University |
Delivery of nucleic acids by porphyrins
|
|
US6610478B1
(en)
|
1996-08-16 |
2003-08-26 |
Yale University |
Phenotypic conversion of cells mediated by external guide sequences
|
|
US5976874A
(en)
*
|
1996-08-16 |
1999-11-02 |
Yale University |
Phenotypic conversion of drug-resistant bacteria to drug-sensitivity
|
|
US6884430B1
(en)
|
1997-02-10 |
2005-04-26 |
Aventis Pharma S.A. |
Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
|
|
US7083786B2
(en)
|
1997-04-03 |
2006-08-01 |
Jensenius Jens Chr |
MASP-2, a complement-fixing enzyme, and uses for it
|
|
PL194095B1
(pl)
|
1997-04-15 |
2007-04-30 |
Commw Scient Ind Res Org |
Wyizolowana cząsteczka kwasu nukleinowego, konstrukt genetyczny, sposób dokonywania zmian poziomu epoksykwasów tłuszczowych, sposób wytwarzania rekombinantowego polipeptydu monooksygenazy w komórce, sposób wytwarzania rekombinantowego polipeptydu monooksygenazy w roślinie transgenicznej, polipeptydrekombinantowy, sposób wytwarzania epoksydowanegokwasu tłuszczowego, roślina transformowana i roślina lub pochodząca z niej komórka
|
|
US7589253B2
(en)
|
1997-04-15 |
2009-09-15 |
Commonwealth Scientific And Industrial Research Organisation |
Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism
|
|
JP2002507985A
(ja)
|
1997-06-30 |
2002-03-12 |
ローヌ−プーラン・ロレ・エス・アー |
横紋筋に核酸を導入する改良法およびその組合せ
|
|
EP1015590A2
(en)
|
1997-09-16 |
2000-07-05 |
CropDesign N.V. |
Cyclin-dependent kinase inhibitors and uses thereof
|
|
DE19741375C2
(de)
*
|
1997-09-19 |
1999-10-21 |
Max Planck Gesellschaft |
Transgene Pflanzen, deren oberirdische Teile früher reifen und vollständig absterben
|
|
WO1999017798A1
(en)
|
1997-10-02 |
1999-04-15 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Methods for the modulation of neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections
|
|
WO1999025815A2
(en)
|
1997-11-18 |
1999-05-27 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Nucleic acids involved in the responder phenotype and applications thereof
|
|
US6013447A
(en)
*
|
1997-11-21 |
2000-01-11 |
Innovir Laboratories, Inc. |
Random intracellular method for obtaining optimally active nucleic acid molecules
|
|
ATE526405T1
(de)
|
1998-03-20 |
2011-10-15 |
Commw Scient Ind Res Org |
Synthetische gene und genetische zusammensetzungen diesen enthaltend
|
|
AUPP249298A0
(en)
|
1998-03-20 |
1998-04-23 |
Ag-Gene Australia Limited |
Synthetic genes and genetic constructs comprising same I
|
|
US6248525B1
(en)
|
1998-03-30 |
2001-06-19 |
Yale University |
Method for identifying essential or functional genes
|
|
CA2331782A1
(en)
|
1998-06-24 |
1999-12-29 |
Musc Foundation For Research Development |
Tissue-specific and target rna-specific ribozymes
|
|
DE19836098A1
(de)
|
1998-07-31 |
2000-02-03 |
Hoechst Schering Agrevo Gmbh |
Pflanzen, die eine modifizierte Stärke synthetisieren, Verfahren zur Herstellung der Pflanzen, ihre Verwendung sowie die modifizierte Stärke
|
|
EP1121437B1
(en)
|
1998-10-15 |
2008-02-20 |
Novartis Vaccines and Diagnostics, Inc. |
Metastatic breast and colon cancer regulated genes
|
|
WO2000028052A2
(en)
|
1998-11-09 |
2000-05-18 |
Planttec Biotechnologie Gmbh |
Nucleic acid molecules from rice encoding an r1 protein and their use for the production of modified starch
|
|
AU1505700A
(en)
|
1998-11-12 |
2000-06-05 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Chimeric promoters capable of mediating gene expression in plants upon pathogen infection and uses thereof
|
|
AU2367600A
(en)
|
1998-12-16 |
2000-07-03 |
Chiron Corporation |
Human cyclin-dependent kinase ((hpnqalre))
|
|
EP1169480A4
(en)
|
1999-04-14 |
2005-02-02 |
Musc Found For Res Dev |
TOXIC AGENTS AND RIBOZYMES SPECIFIC TO TISSUE AND SPECIFIC PATHOGENS
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
AUPQ005299A0
(en)
|
1999-04-29 |
1999-05-27 |
Commonwealth Scientific And Industrial Research Organisation |
Novel genes encoding wheat starch synthases and uses therefor
|
|
AU778695B2
(en)
|
1999-07-20 |
2004-12-16 |
Ges. Fur Erwerb Und Verwertung Von Schutzrechten-Gvs Mbh |
Novel method for the generation and selection of transgenic linseed/flax plants
|
|
US6423885B1
(en)
|
1999-08-13 |
2002-07-23 |
Commonwealth Scientific And Industrial Research Organization (Csiro) |
Methods for obtaining modified phenotypes in plant cells
|
|
AU8466501A
(en)
|
2000-07-21 |
2002-02-05 |
Essentia Biosystems Inc |
Multi-component biological transport systems
|
|
EP1331845B1
(en)
|
2000-11-09 |
2012-01-04 |
Commonwealth Scientific And Industrial Research Organisation |
Barley with reduced ssii activity and starch containing products with a reduced amylopectin content
|
|
ITMI20011364A1
(it)
*
|
2001-06-28 |
2002-12-28 |
Metapontum Agrobios S C R L |
Robozima hammerhead specifico per la stearoyl-acp desaturesi di piante oleaginose differenti
|
|
CA2453531A1
(en)
|
2001-07-10 |
2003-01-23 |
Johnson & Johnson Research Pty Limited |
Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells
|
|
ES2358187T3
(es)
|
2001-07-10 |
2011-05-06 |
JOHNSON & JOHNSON RESEARCH PTY LIMITED |
Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas.
|
|
US8022272B2
(en)
|
2001-07-13 |
2011-09-20 |
Sungene Gmbh & Co. Kgaa |
Expression cassettes for transgenic expression of nucleic acids
|
|
FR2829136B1
(fr)
|
2001-08-29 |
2006-11-17 |
Aventis Pharma Sa |
Derives lipidiques d'aminoglycosides
|
|
US7456335B2
(en)
|
2001-09-03 |
2008-11-25 |
Basf Plant Science Gmbh |
Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
|
|
ATE509120T1
(de)
|
2001-09-18 |
2011-05-15 |
Carnegie Inst Of Washington |
Fusionsproteine zur detektion von analyten
|
|
AU2002359761A1
(en)
|
2001-12-18 |
2003-06-30 |
Invenux, Inc. |
Antibiotic compounds
|
|
EP1481268A4
(en)
|
2002-02-07 |
2005-06-29 |
Covalent Partners Llc |
NANOFILM AND MEMBRANE COMPOSITIONS
|
|
US20040005546A1
(en)
|
2002-02-28 |
2004-01-08 |
Oncolytics Biotech Inc. |
Use of ribozymes in the detection of adventitious agents
|
|
DE10212892A1
(de)
|
2002-03-20 |
2003-10-09 |
Basf Plant Science Gmbh |
Konstrukte und Verfahren zur Regulation der Genexpression
|
|
EP1900827A3
(en)
|
2002-05-21 |
2008-04-16 |
Bayer HealthCare AG |
Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia
|
|
WO2004003150A2
(en)
|
2002-06-26 |
2004-01-08 |
Yale University |
Modulators and modulation of the interacton between rgm and neogenin
|
|
ATE546539T1
(de)
|
2002-07-26 |
2012-03-15 |
Basf Plant Science Gmbh |
Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren
|
|
EP2258724A1
(en)
|
2002-11-21 |
2010-12-08 |
Celltech R & D, Inc. |
Modulating immune responses using multimerized anti-CD83 antibodies
|
|
ATE405653T1
(de)
|
2002-12-19 |
2008-09-15 |
Bayer Cropscience Ag |
Pflanzenzellen und pflanzen, die eine stärke mit erhöhter endviskosität synthetisieren
|
|
WO2006032707A2
(en)
|
2004-09-24 |
2006-03-30 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance to environmental stress
|
|
SI2374819T1
(sl)
|
2003-05-12 |
2017-09-29 |
Helion Biotech Aps |
Protitelesa proteina MASP-2
|
|
JP4923171B2
(ja)
|
2003-06-30 |
2012-04-25 |
コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション |
分枝酵素の活性を改変した小麦、ならびにそれから得たデンプンおよびデンプン含有品
|
|
EP1892306A3
(en)
|
2003-10-06 |
2008-06-11 |
Bayer HealthCare AG |
Methods and kits for investigating cancer
|
|
EP1602926A1
(en)
|
2004-06-04 |
2005-12-07 |
University of Geneva |
Novel means and methods for the treatment of hearing loss and phantom hearing
|
|
US7604947B2
(en)
|
2004-06-09 |
2009-10-20 |
Cornell Research Foundation, Inc. |
Detection and modulation of cancer stem cells
|
|
US8840893B2
(en)
|
2004-06-10 |
2014-09-23 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
|
US7919094B2
(en)
|
2004-06-10 |
2011-04-05 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
|
DK1753456T3
(en)
|
2004-06-10 |
2016-11-28 |
Omeros Corp |
METHODS OF TREATING CONDITIONS CONNECTED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION
|
|
DK1763582T3
(en)
|
2004-07-08 |
2015-01-12 |
Dlf Trifolium As |
Means and method of controlling the flowering of plants
|
|
EP2163635B1
(en)
|
2004-08-02 |
2013-05-22 |
BASF Plant Science GmbH |
Method for isolation of transcription termination sequences
|
|
EP1833291B1
(en)
|
2004-12-30 |
2016-10-05 |
Commonwealth Scientific and Industrial Research Organisation |
Method and means for improving bowel health
|
|
EP1707632A1
(de)
|
2005-04-01 |
2006-10-04 |
Bayer CropScience GmbH |
Phosphorylierte waxy-Kartoffelstärke
|
|
WO2007039256A2
(de)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
|
CA2628505A1
(en)
|
2005-11-08 |
2007-05-18 |
Basf Plant Science Gmbh |
Use of armadillo repeat (arm1) polynucleotides for obtaining resistance to pathogens in plants
|
|
WO2007080143A1
(en)
|
2006-01-12 |
2007-07-19 |
Basf Plant Science Gmbh |
Use of stomatin (stm1) polynucleotides for achieving a pathogen resistance in plants
|
|
AU2007299219A1
(en)
|
2006-04-05 |
2008-03-27 |
Metanomics Gmbh |
Process for the production of a fine chemical
|
|
EP2030021B1
(en)
|
2006-05-18 |
2012-11-21 |
Andreas Reichert |
Method for diagnosing mitochondrial dysfunction
|
|
US8383597B2
(en)
|
2006-05-25 |
2013-02-26 |
Cornell Research Foundation, Inc. |
G proteins in tumor growth and angiogenesis
|
|
BRPI0718137B1
(pt)
|
2006-10-06 |
2016-05-10 |
Johnson & Johnson Res Pty Ltd |
comutadores moleculares e métodos para seu uso
|
|
AU2008206975B2
(en)
|
2007-01-15 |
2013-05-02 |
Basf Plant Science Gmbh |
Use of subtilisin (RNR9) polynucleotides for achieving a pathogen resistance in plants
|
|
CN101631868B
(zh)
|
2007-02-16 |
2016-02-10 |
巴斯福植物科学有限公司 |
用于在单子叶植物中调节胚特异性表达的核酸序列
|
|
CN101917992A
(zh)
|
2007-03-27 |
2010-12-15 |
奥默罗斯公司 |
用于治疗运动障碍的pde7抑制剂的用途
|
|
AU2008252998A1
(en)
|
2007-05-22 |
2008-11-27 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-KO
|
|
CL2008002775A1
(es)
|
2007-09-17 |
2008-11-07 |
Amgen Inc |
Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
|
|
EP2040075A1
(en)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Compounds and markers for surface-enhanced raman scattering
|
|
EP2628486A3
(en)
|
2007-12-14 |
2013-10-30 |
Amgen, Inc. |
Method for treating bone fracture with anti-sclerostin antibodies
|
|
AR069894A1
(es)
|
2007-12-21 |
2010-02-24 |
Basf Plant Science Gmbh |
Plantas con mayor rendimiento produciendo un knock out (silenciamiento) en genes relacionados con la eficiencia en el uso de nitrogeno (ko nue)"
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
EP2100962A1
(en)
|
2008-03-12 |
2009-09-16 |
Biogemma |
Plants having improved resistance to pathogens
|
|
US10517839B2
(en)
|
2008-06-09 |
2019-12-31 |
Cornell University |
Mast cell inhibition in diseases of the retina and vitreous
|
|
US8790664B2
(en)
|
2008-09-05 |
2014-07-29 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Multimodular assembly useful for intracellular delivery
|
|
EP2184351A1
(en)
|
2008-10-30 |
2010-05-12 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Polynucleotides encoding caryophyllene synthase and uses thereof
|
|
ES2363358B1
(es)
|
2009-04-03 |
2012-06-21 |
FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al |
Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
|
|
UA109110C2
(ru)
|
2009-04-22 |
2015-07-27 |
Басф Плант Саєнс Компані Гмбх |
Полинуклеотид, который обеспечивает возможность специфической экспрессии в целых семенах однодольного растения
|
|
EP2475367A1
(en)
|
2009-09-10 |
2012-07-18 |
Centre National De La Recherche Scientifique |
NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES
|
|
EP2305285A1
(en)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Means and methods for treating ischemic conditions
|
|
CN106390117A
(zh)
|
2009-10-16 |
2017-02-15 |
奥默罗斯公司 |
通过抑制masp‑2依赖性补体活化治疗弥散性血管内凝血的方法
|
|
US8962627B2
(en)
|
2009-10-30 |
2015-02-24 |
Prestwick Chemical, Inc. |
Oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors
|
|
EP2322149A1
(en)
|
2009-11-03 |
2011-05-18 |
Universidad del Pais Vasco |
Methods and compositions for the treatment of ischemia
|
|
BR112012013734A2
(pt)
|
2009-12-08 |
2017-01-10 |
Abbott Gmbh & Co Kg |
anticorpos monoclonais contra a proteína rgm a para uso no tratamento da degeneração da camada de fibras nervosas da retina.
|
|
EP2338492A1
(en)
|
2009-12-24 |
2011-06-29 |
Universidad del Pais Vasco |
Methods and compositions for the treatment of alzheimer
|
|
US8476485B2
(en)
|
2010-06-24 |
2013-07-02 |
Academia Sinica |
Non-human animal model for amyotrophic lateral sclerosis (ALS) with loss-of-TDP-43 function
|
|
US9220715B2
(en)
|
2010-11-08 |
2015-12-29 |
Omeros Corporation |
Treatment of addiction and impulse-control disorders using PDE7 inhibitors
|
|
EP4275752A3
(en)
|
2010-11-08 |
2024-02-21 |
Omeros Corporation |
Treatment of addiction and impulse-control disorders using pde7 inhibitors
|
|
US9644035B2
(en)
|
2011-04-08 |
2017-05-09 |
Omeros Corporation |
Methods for treating conditions associated with MASP-2 dependent complement activation
|
|
KR101870915B1
(ko)
|
2011-04-08 |
2018-06-25 |
유니버시티 오브 레스터 |
Masp-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법
|
|
EP2734621B1
(en)
|
2011-07-22 |
2019-09-04 |
President and Fellows of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
WO2013025936A1
(en)
|
2011-08-18 |
2013-02-21 |
Cornell University |
Detection and treatment of metastatic disease
|
|
WO2013039880A1
(en)
|
2011-09-12 |
2013-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Biomarkers and therapeutic targets of hepatocellular cancer
|
|
CA2859564C
(en)
|
2011-12-16 |
2020-04-14 |
Board Of Trustees Of Michigan State University |
P-coumaroyl-coa:monolignol transferase
|
|
SG11201404263TA
(en)
|
2012-01-27 |
2014-08-28 |
Abbvie Deutschland |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
WO2013138463A1
(en)
|
2012-03-14 |
2013-09-19 |
University Of Central Florida Research Foundation, Inc. |
Neurofibromatoses therapeutic agents and screening for same
|
|
EP2666775A1
(en)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
WO2014127835A1
(en)
|
2013-02-22 |
2014-08-28 |
Christian-Albrechts-Universität Zu Kiel |
Plant-derived resistance gene
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
|
NZ719476A
(en)
|
2013-10-17 |
2022-07-29 |
Omeros Corp |
Methods for treating conditions associated with masp-2 dependent complement activation
|
|
US9840699B2
(en)
|
2013-12-12 |
2017-12-12 |
President And Fellows Of Harvard College |
Methods for nucleic acid editing
|
|
WO2015089587A1
(en)
|
2013-12-18 |
2015-06-25 |
Commonwealth Scientific And Industrial Research Organisation |
Lipid comprising long chain polyunsaturated fatty acids
|
|
PH12016502586B1
(en)
|
2014-06-27 |
2023-07-19 |
Commw Scient Ind Res Org |
Lipid comprising docosapentaenoic acid
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
EP3000814A1
(en)
|
2014-09-26 |
2016-03-30 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
IL258821B
(en)
|
2015-10-23 |
2022-07-01 |
Harvard College |
Nucleobase editors and their uses
|
|
IL259225B
(en)
|
2015-11-09 |
2022-09-01 |
Omeros Corp |
Compositions comprising masp-2 inhibitory antibodies and antigen-binding fragments thereof for use in treating tma assoiated with hematopoietic stem cell transplantation
|
|
CN114306593A
(zh)
|
2016-01-05 |
2022-04-12 |
莱斯特大学 |
用于抑制有需要的受试者的纤维化的方法
|
|
CN109152834A
(zh)
|
2016-03-31 |
2019-01-04 |
奥默罗斯公司 |
抑制有需要的受试者的血管发生的方法
|
|
CN109476715B
(zh)
|
2016-05-26 |
2023-06-27 |
纽海姆有限公司 |
产无籽果实的植物
|
|
KR20250103795A
(ko)
|
2016-08-03 |
2025-07-07 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
CA3033327A1
(en)
|
2016-08-09 |
2018-02-15 |
President And Fellows Of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
ES2949801T3
(es)
|
2017-01-09 |
2023-10-03 |
Whitehead Inst Biomedical Res |
Métodos para alterar la expresión génica mediante la perturbación de multímeros de factores de transcripción que estructuran bucles reguladores
|
|
WO2018165504A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
CN110662556A
(zh)
|
2017-03-09 |
2020-01-07 |
哈佛大学的校长及成员们 |
癌症疫苗
|
|
JP2020510439A
(ja)
|
2017-03-10 |
2020-04-09 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
シトシンからグアニンへの塩基編集因子
|
|
US10883089B2
(en)
|
2017-04-04 |
2021-01-05 |
Wisconsin Alumni Research Foundation |
Feruloyl-CoA:monolignol transferases
|
|
US10883090B2
(en)
|
2017-04-18 |
2021-01-05 |
Wisconsin Alumni Research Foundation |
P-coumaroyl-CoA:monolignol transferases
|
|
JP7598137B2
(ja)
|
2017-07-17 |
2024-12-11 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト |
放射線または放射線療法によって引き起こされた放射線誘発性バイスタンダ効果を防止および治療するための組成物および方法
|
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
|
TW202529812A
(zh)
|
2017-08-15 |
2025-08-01 |
美商歐米諾斯公司 |
用於治療和/或預防與造血幹細胞移植有關的移植物抗宿主病和/或瀰漫性肺泡出血和/或靜脈閉塞性病的方法
|
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
|
KR20250107288A
(ko)
|
2017-10-16 |
2025-07-11 |
더 브로드 인스티튜트, 인코퍼레이티드 |
아데노신 염기 편집제의 용도
|
|
WO2019118949A1
(en)
|
2017-12-15 |
2019-06-20 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
WO2019226953A1
(en)
|
2018-05-23 |
2019-11-28 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
JP7536655B2
(ja)
|
2018-05-29 |
2024-08-20 |
オメロス コーポレーション |
Masp-2阻害剤および使用方法
|
|
US11584714B2
(en)
|
2018-05-29 |
2023-02-21 |
Omeros Corporation |
MASP-2 inhibitors and methods of use
|
|
EP3806619A1
(en)
|
2018-06-15 |
2021-04-21 |
Nunhems B.V. |
Seedless watermelon plants comprising modifications in an abc transporter gene
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
CA3119066A1
(en)
|
2018-11-09 |
2020-05-14 |
Wisconsin Alumni Research Foundation |
Bahd acyltransferases
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
EP3942042A1
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
EP3956349A1
(en)
|
2019-04-17 |
2022-02-23 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
IL293550A
(en)
|
2019-12-04 |
2022-08-01 |
Omeros Corp |
2-masp inhibitor compounds, preparations containing them and their uses
|
|
BR112022010890A2
(pt)
|
2019-12-04 |
2022-08-16 |
Omeros Corp |
Composto, composição farmacêutica, e, método para tratar uma doença ou distúrbio associado a serina protease-2 associada à lectina de ligação ao manan
|
|
WO2021113698A1
(en)
|
2019-12-04 |
2021-06-10 |
Omeros Corporation |
Masp-2 inhibitors and methods of use
|
|
TWI834025B
(zh)
|
2020-03-06 |
2024-03-01 |
美商奥默羅斯公司 |
用於治療和/或預防冠狀病毒誘導的急性呼吸窘迫症候群的抑制masp-2的方法
|
|
WO2021226558A1
(en)
|
2020-05-08 |
2021-11-11 |
The Broad Institute, Inc. |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
|
WO2022034474A1
(en)
|
2020-08-10 |
2022-02-17 |
Novartis Ag |
Treatments for retinal degenerative diseases
|
|
CN119768172A
(zh)
|
2022-08-18 |
2025-04-04 |
米托迪治愈有限责任公司 |
具有磷酸二酯酶-7抑制活性的治疗剂在治疗和预防与慢性疲劳、衰竭和/或劳累不耐受有关的疾病中的用途
|
|
WO2024042160A1
(en)
|
2022-08-26 |
2024-02-29 |
Mitodicure Gmbh |
Use of a therapeutic agent with sodium-hydrogen antiporter 1 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance
|