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NO156052C - Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav. - Google Patents

Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav.

Info

Publication number
NO156052C
NO156052C NO83831730A NO831730A NO156052C NO 156052 C NO156052 C NO 156052C NO 83831730 A NO83831730 A NO 83831730A NO 831730 A NO831730 A NO 831730A NO 156052 C NO156052 C NO 156052C
Authority
NO
Norway
Prior art keywords
insulan
esters
procedure
manufacturing human
human
Prior art date
Application number
NO83831730A
Other languages
English (en)
Other versions
NO831730L (no
NO156052B (no
Inventor
Finn Hede Andresen
Per Balschmidt
Kim Ry Hejnaes
Hans Kofod
Original Assignee
Nordisk Insulinlab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab
Publication of NO831730L publication Critical patent/NO831730L/no
Publication of NO156052B publication Critical patent/NO156052B/no
Publication of NO156052C publication Critical patent/NO156052C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
NO83831730A 1982-06-07 1983-05-13 Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav. NO156052C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK254682 1982-06-07
DK254582 1982-06-07
PCT/DK1982/000082 WO1983001074A1 (en) 1981-09-15 1982-09-14 Enzymatic preparation of human insulin or b-30 esters thereof

Publications (3)

Publication Number Publication Date
NO831730L NO831730L (no) 1983-05-13
NO156052B NO156052B (no) 1987-04-06
NO156052C true NO156052C (no) 1987-07-15

Family

ID=26066590

Family Applications (1)

Application Number Title Priority Date Filing Date
NO83831730A NO156052C (no) 1982-06-07 1983-05-13 Fremgangsmaate ved fremstilling av menneskeinsulin eller b-30 estere derav.

Country Status (11)

Country Link
US (1) US4601979A (no)
EP (1) EP0088117B1 (no)
JP (1) JPS58501455A (no)
AU (1) AU551174B2 (no)
CA (1) CA1174623A (no)
DK (1) DK149457C (no)
ES (1) ES8400772A1 (no)
FI (1) FI78119C (no)
IT (1) IT1189353B (no)
NO (1) NO156052C (no)
WO (1) WO1983001074A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3381980D1 (de) * 1982-04-23 1990-12-13 Wako Pure Chem Ind Ltd Verfahren zur halbsynthese von menschlichem insulin und dazu zu verwendende alkalische protease.
EP0294851A3 (de) * 1987-06-12 1990-05-09 Berlin-Chemie Ag Verfahren zur Herstellung von Humaninsulin und seinen Derivaten
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
EP1039920A4 (en) 1997-10-24 2003-05-28 Lilly Co Eli INSULIN ANALOGS ACYLATED BY FATTY ACID
US6531448B1 (en) * 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
US7396903B2 (en) * 2001-11-19 2008-07-08 Novo Nordisk A/S Process for preparing insulin compounds
HU228934B1 (hu) 2001-11-19 2013-06-28 Novo Nordisk As Eljárás inzulinvegyületek elõállítására
US7589233B2 (en) * 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
US8173840B2 (en) * 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
US10611813B2 (en) * 2013-12-23 2020-04-07 Biocon Research Limited Method of production of human insulin methyl ester

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS6339237B2 (no) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
JPS55138392A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DK146482C (da) * 1979-04-13 1986-10-06 Shionogi & Co Fremgangsmaade til fremstilling af et b30-threonin-insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
FI78119B (fi) 1989-02-28
EP0088117B1 (en) 1986-09-24
US4601979A (en) 1986-07-22
FI78119C (fi) 1989-06-12
JPH0526469B2 (no) 1993-04-16
DK149457C (da) 1991-11-25
FI831157L (fi) 1983-04-06
NO831730L (no) 1983-05-13
CA1174623A (en) 1984-09-18
AU551174B2 (en) 1986-04-17
DK213983D0 (da) 1983-05-13
IT8249114A1 (it) 1984-03-14
DK213983A (da) 1983-05-13
ES515713A0 (es) 1983-11-01
IT1189353B (it) 1988-02-04
EP0088117A1 (en) 1983-09-14
DK149457B (da) 1986-06-16
AU8953982A (en) 1983-04-08
NO156052B (no) 1987-04-06
WO1983001074A1 (en) 1983-03-31
JPS58501455A (ja) 1983-09-01
ES8400772A1 (es) 1983-11-01
FI831157A0 (fi) 1983-04-06
IT8249114A0 (it) 1982-09-14

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