NL2000715A1 - Penem-prodrugs. - Google Patents

Penem-prodrugs.

Info

Publication number: NL2000715A1
Authority: NL; Netherlands
Prior art keywords: penem; prodrugs; penem prodrugs
Prior art date: 2006-06-28

Application number

NL2000715A

Other languages

English (en)

Other versions

NL2000715C2 (nl

Inventor

Katherine Elizabeth Brighty

Anthony Marfat

Dale Gordon Mcleod

John Paul O'donnell

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-28

Filing date

2007-06-19

Publication date

2008-01-02

2007-06-19 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2008-01-02 Publication of NL2000715A1 publication Critical patent/NL2000715A1/nl

2008-03-11 Application granted granted Critical

2008-03-11 Publication of NL2000715C2 publication Critical patent/NL2000715C2/nl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/887—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero atom or a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

NL2000715A 2006-06-28 2007-06-19 Penem-prodrugs. NL2000715C2 (nl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US80600006P	2006-06-28	2006-06-28
US80600006		2006-06-28
US91158707P	2007-04-13	2007-04-13
US91158707		2007-04-13

Publications (2)

Publication Number	Publication Date
NL2000715A1 true NL2000715A1 (nl)	2008-01-02
NL2000715C2 NL2000715C2 (nl)	2008-03-11

Family

ID=38463109

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL2000715A NL2000715C2 (nl)	2006-06-28	2007-06-19	Penem-prodrugs.

Country Status (28)

Country	Link
US (2)	US7795243B2 (nl)
EP (1)	EP2044085B1 (nl)
JP (2)	JP4397435B2 (nl)
KR (1)	KR101060448B1 (nl)
AP (1)	AP2008004705A0 (nl)
AR (1)	AR061646A1 (nl)
AT (1)	ATE493419T1 (nl)
AU (1)	AU2007263519B2 (nl)
BR (1)	BRPI0712740A2 (nl)
CA (1)	CA2655485C (nl)
CL (1)	CL2007001910A1 (nl)
CR (1)	CR10467A (nl)
DE (1)	DE602007011622D1 (nl)
DK (1)	DK2044085T3 (nl)
EA (1)	EA200870584A1 (nl)
EC (1)	ECSP088947A (nl)
GT (1)	GT200700050A (nl)
IL (1)	IL195383A0 (nl)
MA (1)	MA30568B1 (nl)
MX (1)	MX2009000116A (nl)
NL (1)	NL2000715C2 (nl)
NO (1)	NO20090392L (nl)
PE (1)	PE20080940A1 (nl)
SV (1)	SV2008003139A (nl)
TN (1)	TNSN08537A1 (nl)
TW (1)	TW200816999A (nl)
UY (1)	UY30439A1 (nl)
WO (1)	WO2008001212A2 (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PE20080940A1 (es) *	2006-06-28	2008-07-09	Pfizer Prod Inc	Profarmacos de penem
US20080125408A1 (en) *	2006-11-14	2008-05-29	Pfizer Inc	Penem prodrug
WO2009108704A1 (en) *	2008-02-25	2009-09-03	Semafore Pharmaceuticals, Inc.	O-alkylated pi-3 kinase inhibitor prodrug combination
KR100916052B1 (ko)	2009-02-24	2009-09-08	코오롱건설주식회사	진공이송 쓰레기 수거시스템의 쓰레기 배출밸브
CN102471248B (zh) *	2009-08-10	2015-01-07	Bhi有限合伙公司	用于递送1,3-丙二磺酸的方法、化合物和组合物
US11554112B2 (en)	2018-06-07	2023-01-17	Herum Therapeutics International Limited	Combinations of β-lactam compounds and probenecid and uses thereof
CA3129337A1 (en) *	2019-02-13	2020-08-20	Iterum Therapeutics International Limited	Combinations of beta-lactam compounds and probenecid and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4619924A (en) *	1984-05-18	1986-10-28	Pfizer Inc.	2-alkylthiopenem derivatives
US4870170A (en) *	1985-10-17	1989-09-26	Pfizer Inc.	Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
WO1988008845A1 (en) *	1987-05-11	1988-11-17	Pfizer Inc.	Diastereomeric 5r,6s-6-(1r-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids
GB8713515D0 (en)	1987-06-10	1987-07-15	Erba Farmitalia	Methoxymethyl compounds
US4874877A (en) *	1988-04-19	1989-10-17	Pfizer Inc.	Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
AU8333991A (en)	1990-08-20	1992-03-17	Suntory Limited	Penem compounds
DE69130363T2 (de)	1990-08-20	1999-04-22	Suntory Limited, Osaka	Antibakterielle penemverbindungen
WO2004067532A1 (ja)	2003-01-31	2004-08-12	Meiji Seika Kaisha, Ltd.	新規カルバペネム誘導体
PE20080940A1 (es) *	2006-06-28	2008-07-09	Pfizer Prod Inc	Profarmacos de penem
WO2008008845A2 (en) *	2006-07-11	2008-01-17	Microchips, Inc.	Multi-reservoir pump device for dialysis, biosensing, or delivery of substances
US20080125408A1 (en) *	2006-11-14	2008-05-29	Pfizer Inc	Penem prodrug

2007
- 2007-06-14 PE PE2007000755A patent/PE20080940A1/es not_active Application Discontinuation
- 2007-06-18 CA CA2655485A patent/CA2655485C/en not_active Expired - Fee Related
- 2007-06-18 AP AP2008004705A patent/AP2008004705A0/xx unknown
- 2007-06-18 JP JP2009517474A patent/JP4397435B2/ja not_active Expired - Fee Related
- 2007-06-18 EP EP07734929A patent/EP2044085B1/en active Active
- 2007-06-18 KR KR1020087031533A patent/KR101060448B1/ko not_active Expired - Fee Related
- 2007-06-18 BR BRPI0712740-5A patent/BRPI0712740A2/pt not_active IP Right Cessation
- 2007-06-18 MX MX2009000116A patent/MX2009000116A/es active IP Right Grant
- 2007-06-18 AT AT07734929T patent/ATE493419T1/de not_active IP Right Cessation
- 2007-06-18 AU AU2007263519A patent/AU2007263519B2/en not_active Ceased
- 2007-06-18 WO PCT/IB2007/001843 patent/WO2008001212A2/en not_active Ceased
- 2007-06-18 EA EA200870584A patent/EA200870584A1/ru unknown
- 2007-06-18 DE DE602007011622T patent/DE602007011622D1/de active Active
- 2007-06-18 DK DK07734929.8T patent/DK2044085T3/da active
- 2007-06-19 NL NL2000715A patent/NL2000715C2/nl not_active IP Right Cessation
- 2007-06-25 GT GT200700050A patent/GT200700050A/es unknown
- 2007-06-26 UY UY30439A patent/UY30439A1/es not_active Application Discontinuation
- 2007-06-26 AR ARP070102825A patent/AR061646A1/es not_active Application Discontinuation
- 2007-06-27 TW TW096123288A patent/TW200816999A/zh unknown
- 2007-06-28 CL CL2007001910A patent/CL2007001910A1/es unknown
- 2007-06-28 US US11/769,849 patent/US7795243B2/en active Active
2008
- 2008-06-30 US US12/164,818 patent/US7795244B2/en active Active
- 2008-11-19 IL IL195383A patent/IL195383A0/en unknown
- 2008-11-27 CR CR10467A patent/CR10467A/es not_active Application Discontinuation
- 2008-12-08 EC EC2008008947A patent/ECSP088947A/es unknown
- 2008-12-23 SV SV2008003139A patent/SV2008003139A/es not_active Application Discontinuation
- 2008-12-26 MA MA31512A patent/MA30568B1/fr unknown
- 2008-12-26 TN TNP2008000537A patent/TNSN08537A1/fr unknown
2009
- 2009-01-27 NO NO20090392A patent/NO20090392L/no not_active Application Discontinuation
- 2009-09-04 JP JP2009204301A patent/JP5152527B2/ja active Active

Also Published As

Publication number	Publication date
BRPI0712740A2 (pt)	2012-06-05
ECSP088947A (es)	2009-01-30
EA200870584A1 (ru)	2009-06-30
NL2000715C2 (nl)	2008-03-11
AP2008004705A0 (en)	2008-12-31
CA2655485C (en)	2011-08-02
EP2044085B1 (en)	2010-12-29
US7795243B2 (en)	2010-09-14
CR10467A (es)	2009-01-19
TW200816999A (en)	2008-04-16
JP2009542616A (ja)	2009-12-03
AR061646A1 (es)	2008-09-10
GT200700050A (es)	2008-02-01
CL2007001910A1 (es)	2008-01-11
MA30568B1 (fr)	2009-07-01
US20090042853A1 (en)	2009-02-12
IL195383A0 (en)	2009-08-03
DE602007011622D1 (en)	2011-02-10
JP4397435B2 (ja)	2010-01-13
CA2655485A1 (en)	2008-01-03
PE20080940A1 (es)	2008-07-09
KR20090015147A (ko)	2009-02-11
TNSN08537A1 (fr)	2010-04-14
EP2044085A2 (en)	2009-04-08
ATE493419T1 (de)	2011-01-15
AU2007263519A1 (en)	2008-01-03
WO2008001212A3 (en)	2008-03-20
WO2008001212A2 (en)	2008-01-03
US20080009474A1 (en)	2008-01-10
JP2010013468A (ja)	2010-01-21
JP5152527B2 (ja)	2013-02-27
KR101060448B1 (ko)	2011-08-29
US7795244B2 (en)	2010-09-14
MX2009000116A (es)	2009-01-23
NO20090392L (no)	2009-01-27
UY30439A1 (es)	2008-01-31
HK1134928A1 (en)	2010-05-20
AU2007263519B2 (en)	2011-05-19
SV2008003139A (es)	2010-01-12
DK2044085T3 (da)	2011-03-07

Publication	Publication Date	Title
FR2909857B1 (fr)	2009-03-06	Endovalve.
DE602006019782D1 (de)	2011-03-03	Kapselperforationsmodul
DE602007008423D1 (de)	2010-09-23	Flüssigkeitshärtung
DE602007000258D1 (de)	2009-01-02	Kassetteneinspannmechanismus
DE602007009337D1 (de)	2010-11-04	Tastfeedbackvorrichtung
EP2077271A4 (en)	2010-09-15	Macrolide derivative
DE502007004205D1 (de)	2010-08-05	Tt
DE502007001629D1 (de)	2009-11-12	Rfahren
ATE546437T1 (de)	2012-03-15	Aminomethyl-4-imidazole
ATE534010T1 (de)	2011-12-15	Zielfernrohr
FI20065107A0 (fi)	2006-02-13	Impulssijärjestely
FI20061014A0 (fi)	2006-11-17	Diffuusiopinnoitusmenetelmä
NL2000715A1 (nl)	2008-01-02	Penem-prodrugs.
FR2909834B1 (fr)	2011-04-01	Andaineuse transversale.
FR2903669B3 (fr)	2008-06-20	02isse demontable.
ITCE20060002A1 (it)	2007-09-11	Patok.
ES1062074Y (es)	2006-08-01	Autorefrigerante solar-ecologico.
ES1061980Y (es)	2006-08-01	Contenedor-palet.
ITRA20060010A1 (it)	2007-08-11	Espositore.
ITPI20060037A1 (it)	2006-07-04	Carsy.
ITPA20060014A1 (it)	2007-10-06	Rubino - macrotex.
ITSS20060011A1 (it)	2008-04-30	Posablocchi.
ITPA20060005A1 (it)	2007-08-15	Calciocards.
ITAV20060001A1 (it)	2006-05-04	Generafiume.
ITPA20060004U1 (it)	2007-08-02	Contenitore-dispencer-raccoglitore.

Legal Events

Date	Code	Title	Description
2008-03-03	AD1A	A request for search or an international type search has been filed
2008-03-03	RD2N	Patents in respect of which a decision has been taken or a report has been made (novelty report)	Effective date: 20080110
2008-05-01	PD2B	A search report has been drawn up
2011-01-12	V1	Lapsed because of non-payment of the annual fee	Effective date: 20110101