[go: up one dir, main page]

MX9100675A - 2-amino-1,2,3,4-tetrahidronaftalenos,3-aminocromanos y 3-aminotiocromanos substituidos en el anillo,procedimiento para su preparacion y composiciones farmaceuticas que los contienen - Google Patents

2-amino-1,2,3,4-tetrahidronaftalenos,3-aminocromanos y 3-aminotiocromanos substituidos en el anillo,procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Info

Publication number
MX9100675A
MX9100675A MX9100675A MX9100675A MX9100675A MX 9100675 A MX9100675 A MX 9100675A MX 9100675 A MX9100675 A MX 9100675A MX 9100675 A MX9100675 A MX 9100675A MX 9100675 A MX9100675 A MX 9100675A
Authority
MX
Mexico
Prior art keywords
alkyl
substituted
hydrogen
aryl
cycloalkyl
Prior art date
Application number
MX9100675A
Other languages
English (en)
Inventor
Craig Steven Hoechstetter
Diane Lynn Huser
Charles Johnson Paget Jr
John Mehnert Schaus
Robert Daniel Titus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX9100675A publication Critical patent/MX9100675A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Saccharide Compounds (AREA)
MX9100675A 1990-08-15 1991-08-15 2-amino-1,2,3,4-tetrahidronaftalenos,3-aminocromanos y 3-aminotiocromanos substituidos en el anillo,procedimiento para su preparacion y composiciones farmaceuticas que los contienen MX9100675A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56798590A 1990-08-15 1990-08-15

Publications (1)

Publication Number Publication Date
MX9100675A true MX9100675A (es) 1992-04-01

Family

ID=24269428

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9100675A MX9100675A (es) 1990-08-15 1991-08-15 2-amino-1,2,3,4-tetrahidronaftalenos,3-aminocromanos y 3-aminotiocromanos substituidos en el anillo,procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Country Status (25)

Country Link
US (5) US5286753A (es)
EP (1) EP0471515B1 (es)
JP (1) JPH04244050A (es)
KR (1) KR920004331A (es)
CN (1) CN1039967C (es)
AT (1) ATE149480T1 (es)
AU (1) AU652569B2 (es)
CA (1) CA2048846A1 (es)
CZ (1) CZ281137B6 (es)
DE (1) DE69124868T2 (es)
DK (1) DK0471515T3 (es)
ES (1) ES2100211T3 (es)
FI (1) FI913833A7 (es)
GR (1) GR3023409T3 (es)
HU (1) HU218668B (es)
IE (1) IE912880A1 (es)
IL (1) IL99175A (es)
MX (1) MX9100675A (es)
MY (1) MY110619A (es)
NO (1) NO176094C (es)
NZ (1) NZ239371A (es)
PT (1) PT98641B (es)
RU (1) RU2060245C1 (es)
YU (1) YU48695B (es)
ZA (1) ZA916425B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE121740T1 (de) * 1989-03-22 1995-05-15 Ciba Geigy Ag Neue benzothiopyranylamine.
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5340838A (en) * 1990-05-04 1994-08-23 Eli Lilly And Company Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
ATE151419T1 (de) * 1991-02-08 1997-04-15 Lilly Co Eli Ringsubstituierte 2-amino-1,2,3,4- tetrahydronaphthaline
AU654573B2 (en) * 1991-08-21 1994-11-10 Eli Lilly And Company Benzo(f)quinolinones
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
EP0697894A4 (en) * 1993-03-31 1996-05-01 Univ Pennsylvania DOPAMINE D-3 AND SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US5482942A (en) * 1994-06-28 1996-01-09 American Home Products Corporation (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
KR100571060B1 (ko) * 1996-09-26 2006-04-14 츄가이 세이야꾸 가부시키가이샤 인간의 부갑상선 호르몬 관련 펩티드에 대한 항체
WO1998048786A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company AMINOTETRALINS AS 5-HT1Dα AGONISTS
US6355674B1 (en) 1997-04-30 2002-03-12 Eli Lilly And Company Aminotetralins as 5-HT1D α Agonists
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
US5962488A (en) 1998-04-08 1999-10-05 Roberts Laboratories, Inc. Stable pharmaceutical formulations for treating internal bowel syndrome containing isoxazole derivatives
FR2792529B1 (fr) * 1999-04-26 2001-09-28 Sod Conseils Rech Applic Nouvelles compositions pharmaceutiques comprenant des derives de 2-isoxazole-8-aminotetralines
US7060847B2 (en) * 2003-07-18 2006-06-13 Roche Diagnostics Operations, Inc. Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
EP0026848B1 (de) * 1979-09-14 1983-05-04 Sandoz Ag Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
JPS5970653A (ja) * 1982-10-15 1984-04-21 Takeda Chem Ind Ltd 眼圧低下剤
US4520030A (en) * 1983-12-12 1985-05-28 Synthelabo Anti-ulcer agents
US4975461A (en) * 1986-06-19 1990-12-04 E. R. Squibb & Sons, Inc. P-aminophenols, derivatives thereof and method of use
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
CA1335591C (en) * 1988-05-23 1995-05-16 James Arthur Nixon Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
US4873265A (en) * 1988-07-14 1989-10-10 Thomes Pharmacal Co., Inc. Anti-infective methods and compositions
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
ZA901277B (en) * 1989-02-27 1991-10-30 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
DE69005625T2 (de) * 1989-04-27 1994-05-11 Upjohn Co Substituierte 3-amino-chromane.
US5306830A (en) * 1989-04-27 1994-04-26 The Upjohn Company Substituted 3-amino chromans
BE1004067A6 (fr) * 1989-05-23 1992-09-15 Cockerill Sambre Sa Dispositif d'arret d'urgence pour installation industrielle.
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
KR100195656B1 (ko) * 1989-05-31 1999-06-15 로버트 에이.아미테이지 치료학적으로 유용한 2-아미노테트랄린 유도체
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
ATE151419T1 (de) * 1991-02-08 1997-04-15 Lilly Co Eli Ringsubstituierte 2-amino-1,2,3,4- tetrahydronaphthaline
FR2689509B1 (fr) * 1992-04-01 1994-06-03 Adir Nouveaux derives spiraniques du 3-amino chromane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
US5470977A (en) 1995-11-28
NZ239371A (en) 1993-01-27
DE69124868T2 (de) 1997-07-10
CZ281137B6 (cs) 1996-06-12
CA2048846A1 (en) 1992-02-16
US5466709A (en) 1995-11-14
NO913175D0 (no) 1991-08-14
CN1059903A (zh) 1992-04-01
MY110619A (en) 1998-09-30
ES2100211T3 (es) 1997-06-16
DE69124868D1 (de) 1997-04-10
ZA916425B (en) 1993-04-28
HU912708D0 (en) 1992-01-28
IE912880A1 (en) 1992-02-26
CS249391A3 (en) 1992-03-18
US5426229A (en) 1995-06-20
NO176094C (no) 1995-02-01
NO913175L (no) 1992-02-17
GR3023409T3 (en) 1997-08-29
HUT61965A (en) 1993-03-29
EP0471515B1 (en) 1997-03-05
ATE149480T1 (de) 1997-03-15
DK0471515T3 (da) 1997-07-21
FI913833A0 (fi) 1991-08-13
EP0471515A1 (en) 1992-02-19
IL99175A0 (en) 1992-07-15
IL99175A (en) 1998-06-15
AU652569B2 (en) 1994-09-01
US5552444A (en) 1996-09-03
AU8240391A (en) 1992-02-20
YU140291A (sh) 1994-01-20
HU218668B (hu) 2000-10-28
PT98641A (pt) 1992-06-30
KR920004331A (ko) 1992-03-27
PT98641B (pt) 1999-01-29
US5286753A (en) 1994-02-15
FI913833L (fi) 1992-02-16
CN1039967C (zh) 1998-09-30
FI913833A7 (fi) 1992-02-16
NO176094B (no) 1994-10-24
YU48695B (sh) 1999-07-28
JPH04244050A (ja) 1992-09-01
RU2060245C1 (ru) 1996-05-20

Similar Documents

Publication Publication Date Title
MX9100675A (es) 2-amino-1,2,3,4-tetrahidronaftalenos,3-aminocromanos y 3-aminotiocromanos substituidos en el anillo,procedimiento para su preparacion y composiciones farmaceuticas que los contienen
ES2080919T3 (es) Nuevos derivados de bencimidazol y de azabencimidazol, antagonistas de los receptores al tromboxano, sus procedimientos de preparacion, intermediarios de sintesis, composiciones que los contienen.
BR1101017A (pt) Distamicina a análoga; processo para a apresentação de um composto; composição farmacêutica contendo um composto; e uso de um composto
FI950016A0 (fi) Heterosykliset yhdisteet lääkeaineena
ES2623982T3 (es) Compuestos heterocíclicos de unión a receptor de quimiocina con eficacia potenciada
MX9204622A (es) Nuevos derivados de 3,5-di-tert-butil-4-hidroxifenilo, procedimiento para su preparacion y composicion farmaceutica que los contiene.
RU95114528A (ru) Аминопроизводные, способ получения, фармацевтическая композиция способ лечения
ATE10804T1 (de) Ein diphenylhydantoin-derivat enthaltende pharmazeutische zusammensetzung, verwendete derivate und ihre herstellung.
MX19637A (es) 2-amino-1,2,3,4-tetrahidronaftalenos y 3-aminocromanos substituidos en el anillo y procedimiento para su preparacion.
EE200000059A (et) Tetrahüdro-gamma-karboliinid
PT97991A (pt) Processo para a preparacao de derivados de 2-(aminoalquil)-5-(arilalquil)-1,3-dioxanos e de composicoes farmaceuticas que os contem
MX11866A (es) Nuevas cicloalquilamidas y procedimiento para su preparacion.
MX9201279A (es) Derivados de 1-fenil-3-aza bi ciclo alquil-imidazolidin-2-onas, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
ES2118343T3 (es) Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ES2074343T3 (es) Nuevas feniletanolamino- y feniletanolaminometil-tetralinas, procedimiento para su preparacion, intermediarios en este procedimiento y composiciones farmaceuticas que los contienen.
DE3373097D1 (en) Benzothiopyranopyridinones and their salts, their preparation and use as medicaments, and compositions containing them
AR018675A1 (es) Derivados de 3-(2-oxo-[1,3¿i¿]bipirrolidinil-3-ilidenometil)-cefem, una composicion farmaceutica y el uso de los mismos para la manufactura de un medicamento.
ES2060095T3 (es) Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen.
KR940014411A (ko) 신규 세팔로스포린계 항생제(v)
DE69011235D1 (de) Derivate von N-(Vincristinyl-23) und N-(Noranhydro-5-vinblastinyl-23) von Amino-1-methylphosphonsäure, ihre Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.
AR003409A1 (es) Compuestos agonistas de receptores beta-adrenergicos, composicion que los comprende e intermediarios para prepararlos.
KR940014408A (ko) 신규 세팔로스포린계 항생제(ii)

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees