[go: up one dir, main page]

SE8004002L - Terapeutiskt anvendbara tetralinderivat - Google Patents

Terapeutiskt anvendbara tetralinderivat

Info

Publication number
SE8004002L
SE8004002L SE8004002A SE8004002A SE8004002L SE 8004002 L SE8004002 L SE 8004002L SE 8004002 A SE8004002 A SE 8004002A SE 8004002 A SE8004002 A SE 8004002A SE 8004002 L SE8004002 L SE 8004002L
Authority
SE
Sweden
Prior art keywords
carbon atoms
compounds
alkyl group
group
therapeutically applicable
Prior art date
Application number
SE8004002A
Other languages
English (en)
Inventor
Folke Lars-Erik Arvidsson
Per Arvid Emil Carlsson
Uli Alf Hacksell
John Stephan Mikael Hjort
Per Lennart Lindberg
John Lars Gunnar Nilsson
Domingo Sanchez
Hakan Vilhelm Wikstrom
Original Assignee
Arvidsson Folke Lars Erik
Per Arvid Emil Carlsson
Hacksell Uli A
John Stephan Mikael Hjort
Per Lennart Lindberg
John Lars Gunnar Nilsson
Domingo Sanchez
Hakan Vilhelm Wikstrom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arvidsson Folke Lars Erik, Per Arvid Emil Carlsson, Hacksell Uli A, John Stephan Mikael Hjort, Per Lennart Lindberg, John Lars Gunnar Nilsson, Domingo Sanchez, Hakan Vilhelm Wikstrom filed Critical Arvidsson Folke Lars Erik
Priority to SE8004002A priority Critical patent/SE8004002L/sv
Priority to AU71797/81A priority patent/AU7179781A/en
Priority to PCT/SE1981/000155 priority patent/WO1981003491A1/en
Priority to JP56501683A priority patent/JPS57500694A/ja
Priority to FI822226A priority patent/FI822226A7/sv
Priority to EP81850092A priority patent/EP0041488A1/en
Priority to ES502565A priority patent/ES502565A0/es
Publication of SE8004002L publication Critical patent/SE8004002L/sv
Priority to DK32982A priority patent/DK32982A/da
Priority to NO820255A priority patent/NO820255L/no
Priority to ES512401A priority patent/ES512401A0/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8004002A 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat SE8004002L (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat
AU71797/81A AU7179781A (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
PCT/SE1981/000155 WO1981003491A1 (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
JP56501683A JPS57500694A (sv) 1980-05-29 1981-05-26
FI822226A FI822226A7 (sv) 1980-05-29 1981-05-26 Terapeutiskt användbara tetralinderivat.
EP81850092A EP0041488A1 (en) 1980-05-29 1981-05-26 Therapeutically useful tetralin derivatives
ES502565A ES502565A0 (es) 1980-05-29 1981-05-28 Un procedimiento para preparar derivados de tetralina
DK32982A DK32982A (da) 1980-05-29 1982-01-26 Terapeutisk nyttige tetralinderivater
NO820255A NO820255L (no) 1980-05-29 1982-01-28 Terapeutisk nyttige tetralin-derivater.
ES512401A ES512401A0 (es) 1980-05-29 1982-05-20 "un procedimiento para preparar derivados de tetralina".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat

Publications (1)

Publication Number Publication Date
SE8004002L true SE8004002L (sv) 1981-11-30

Family

ID=20341076

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8004002A SE8004002L (sv) 1980-05-29 1980-05-29 Terapeutiskt anvendbara tetralinderivat

Country Status (7)

Country Link
EP (1) EP0041488A1 (sv)
JP (1) JPS57500694A (sv)
DK (1) DK32982A (sv)
ES (2) ES502565A0 (sv)
NO (1) NO820255L (sv)
SE (1) SE8004002L (sv)
WO (1) WO1981003491A1 (sv)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US5153225A (en) * 1986-12-10 1992-10-06 Bayer Aktiengesellschaft Substituted basic 2-aminotetralin in pharmaceuticals
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
US4845221A (en) * 1988-04-15 1989-07-04 American Home Products Corporation Serotonergic substituted piperazinyl tetralins
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
US5026707A (en) * 1988-05-23 1991-06-25 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
DE3832571A1 (de) * 1988-09-24 1990-05-31 Boehringer Ingelheim Kg Verwendung von 2,7-diamino-1,2,3,4-tetrahydronaphthalinen als arzneimittel, neue 2,7-diamino-1,2,3,4-tetrahydronaphthaline sowie verfahren zu ihrer herstellung
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
CA2026775C (en) * 1989-01-09 1998-04-07 Per Arvid Emil Carlsson Halo substituted aminotetralins
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
ZA901277B (en) * 1989-02-27 1991-10-30 Lilly Co Eli Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes
GB8907865D0 (en) * 1989-04-07 1989-05-24 Wyeth John & Brother Ltd Tetrahydroquinoline derivatives
US5234945A (en) * 1989-05-09 1993-08-10 Whitby Research, Inc. Method of producing body weight and food intake using a dopamine D2 receptor agonist
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
KR100195656B1 (ko) * 1989-05-31 1999-06-15 로버트 에이.아미테이지 치료학적으로 유용한 2-아미노테트랄린 유도체
DE3919624A1 (de) * 1989-06-15 1990-12-20 Boehringer Ingelheim Kg Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
SE8904127D0 (sv) * 1989-12-07 1989-12-07 Astra Ab New biocyclic amino-substituted compounds
EP0450238A1 (en) * 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Novel compounds for the treatment of migraine
US5194439A (en) * 1990-04-06 1993-03-16 John Wyeth & Brother Limited N-(2,3-dihydro-1,4-benzodioxinyl)-N-substituted aminopyrido-fused cycloalkanes
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
KR100207876B1 (ko) * 1990-10-12 1999-07-15 로버트 에이. 아미테이지 치료학적으로 유용한 2-아미노테트랄린 유도체
ATE151419T1 (de) * 1991-02-08 1997-04-15 Lilly Co Eli Ringsubstituierte 2-amino-1,2,3,4- tetrahydronaphthaline
CA2111957A1 (en) * 1991-06-27 1993-01-07 Richard A. Glennon Sigma receptor ligands and the use thereof
US5824680A (en) * 1991-08-31 1998-10-20 Bayer Aktiengesellschaft Ipsapirone for the treatment of alzheimer's disease by improving memory
TW239127B (sv) * 1991-12-20 1995-01-21 Hoffmann La Roche
AU7177694A (en) * 1993-06-23 1995-01-17 Cambridge Neuroscience, Inc. Sigma receptor ligands and the use thereof
FR2707636B1 (fr) * 1993-06-29 1995-09-15 Inst Francais Du Petrole Composition sulfo-uréique résultant de l'action de l'urée sur une boue sulfurique d'origine pétrolière, procédé de préparation et utilisation comme source de matière fertilisante.
US7829587B2 (en) 2008-01-09 2010-11-09 Allergan, Inc. Substituted 2-aminotetralin derivatives as selective alpha 2B agonist
WO2009121872A2 (en) 2008-04-01 2009-10-08 Abbott Gmbh & Co. Kg Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy
BRPI0920645A2 (pt) * 2008-10-13 2016-01-12 Interquim Sa processo para a preparação de compostos de (s)-(-)-2-(n-propilamino_-5- metoxitetralma e (s)-(-)-2-(n-propilamino)-5-hidroxitetralina opticamente ativos
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
EP2338873A1 (en) * 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
JP2014521682A (ja) 2011-08-05 2014-08-28 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー アミノクロマン、アミノチオクロマンおよびアミノ−１，２，３，４−テトラヒドロキノリン誘導体、これらを含有する医薬組成物、ならびに治療におけるこれらの使用
CN104011028A (zh) 2011-11-18 2014-08-27 艾伯维德国有限责任两合公司 N-取代的氨基苯并环庚烯、氨基四氢化萘、氨基茚满和苯烷基胺衍生物、包含所述衍生物的药物组合物及其在治疗中的用途
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
JP6324956B2 (ja) 2012-07-20 2018-05-16 バイエル・ファルマ・アクティエンゲゼルシャフト 置換アミノインダン−およびアミノテトラリンカルボン酸ならびにその使用
CA2879369C (en) 2012-07-20 2020-09-22 Bayer Pharma Aktiengesellschaft Novel 5-aminotetrahydroquinoline-2-carboxylic acids and use thereof
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
MX2016004934A (es) 2013-10-17 2016-12-20 Abbvie Deutschland Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia.
CN105992764A (zh) 2013-10-17 2016-10-05 艾伯维德国有限责任两合公司 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物，包含其的药物组合物及其在治疗中的用途
TW202342012A (zh) 2021-12-29 2023-11-01 德商拜耳廠股份有限公司 製備用作醫藥活性化合物的（５ｓ）－｛［２－（４－羧基苯基）乙基］［２－（２－｛［３－氯－４＇－（三氟甲基）聯苯－４－基］甲氧基｝苯基）乙基］胺基｝－５，６，７，８－四氫喹啉－２－羧酸及其結晶形式之方法
TW202342034A (zh) 2021-12-29 2023-11-01 德商拜耳廠股份有限公司 心肺病症之治療

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440440A (en) * 1972-10-06 1976-06-23 Manuf Prod Pharma Tetrahydronaphthalene derivatives
US3969468A (en) * 1972-10-31 1976-07-13 Kyowa Hakko Kogyo Co., Ltd. 2-Amino-1,2,3,4-tetrahydronaphthalene derivatives
JPS50135063A (sv) * 1974-03-28 1975-10-25
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE2816122A1 (de) * 1978-04-14 1979-10-25 Bayer Ag 1,8-diamino-1,2,3,4-tetrahydronaphthalin
JPS639500B2 (sv) * 1978-07-14 1988-02-29 Amerikan Hosupitaru Sapurai Corp
EP0026848B1 (de) * 1979-09-14 1983-05-04 Sandoz Ag Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten
US4556676A (en) * 1979-11-01 1985-12-03 Pfizer Inc. Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine

Also Published As

Publication number Publication date
ES8401443A1 (es) 1983-12-01
WO1981003491A1 (en) 1981-12-10
JPS57500694A (sv) 1982-04-22
DK32982A (da) 1982-01-26
ES8400730A1 (es) 1983-11-01
ES512401A0 (es) 1983-12-01
EP0041488A1 (en) 1981-12-09
ES502565A0 (es) 1983-11-01
NO820255L (no) 1982-01-28

Similar Documents

Publication Publication Date Title
SE8004002L (sv) Terapeutiskt anvendbara tetralinderivat
DE3260529D1 (en) Therapeutically useful 1-alkyl-2-aminotetralin derivatives
GB2124077B (en) Immunomodulating agent
HUT39443A (en) Process for producing new triptamine derivatives and pharmaceutical compositions containing them
MX21088A (es) N-heteroanil-purin-6-aminas, y un proceso para su preparacion y su uso como medicamentos.
DE69030665D1 (de) (1,2n) und (3,2n)-karbozyklische-2-amino-tetralinderivate
DE3666223D1 (en) Anticonvulsant agents
ZA86173B (en) Octahydroindolizine compounds useful as analgesics
DE3368609D1 (en) Carbacyclines, process for their preparation and their use as medicines
SE8901060D0 (sv) New compounds
ES8301963A1 (es) Un procedimiento para preparacion de nuevas piperidinoquinazolinas.
SE8305362D0 (sv) Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8004002-5